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MIRAGE
Hepatocyte growth factor

Summary
UniProt ID
P14210
Gene Symbol
  • HGF
  • HPTA
Gene ID
3082
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P14210
PubChem
P14210
RaftProt
P14210
Re-Glyco
P14210
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Growth factor
  • Kringle
  • Non-syndromic deafness
  • Pyrrolidone carboxylic acid
  • Reference proteome
  • Repeat
  • Serine protease homolog
  • Signal
Gene Ontology (GO)
Displaying all 4 entries
GO Term
platelet alpha granule lumen
extracellular region
extracellular space
membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQPRPWCYTLDPHTRWEYCAIKTCADNTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSESPWCFTTDPNIRVGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKVPQS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
294
402
476 O-linked (GalNAc...) threonine
566
653
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 11 - 18 of 18 in total
Pathway Name Organism
MET activates STAT3 Homo sapiens
MET interacts with TNS proteins Homo sapiens
MET receptor recycling Homo sapiens
Negative regulation of MET activity Homo sapiens
PI3K/AKT Signaling Homo sapiens
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Homo sapiens
Platelet degranulation Homo sapiens
RAF/MAP kinase cascade Homo sapiens
Disease
Displaying entries 1 - 10 of 16 in total
DO ID Disease Name Source
DOID:0050852 limb ischemia
DOID:0081267 graft-versus-host disease
DOID:0110497 autosomal recessive nonsyndromic deafness 39
DOID:10126 keratoconus
DOID:10763 hypertension
DOID:11446 sciatic neuropathy
DOID:11830 myopia
DOID:12306 vitiligo
DOID:13550 angle-closure glaucoma
DOID:2741 bilirubin metabolic disorder
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025