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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Vascular cell adhesion protein 1
Summary
- UniProt ID
- P19320
- Gene Symbol
-
- VCAM1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011586
- GlyConnect
- GlyGen
- P19320
- PubChem
- P19320
- The Human Metabolome Database
- HMDBP02667
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cellular response to amyloid-beta |
| chronic inflammatory response |
| inflammatory response |
| cell adhesion |
| leukocyte cell-cell adhesion |
| amine metabolic process |
| B cell differentiation |
| GO Term |
|---|
| extracellular space |
| Golgi apparatus |
| plasma membrane |
| microvillus |
| alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex |
| extracellular exosome |
| filopodium |
| sarcolemma |
| apical part of cell |
| podosome |
| GO Term |
|---|
| cell adhesion molecule binding |
| cell adhesion mediator activity |
| primary amine oxidase activity |
| integrin binding |
Sequence
MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWRTQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPEIHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEVTFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGGSVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKNRKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVRSEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSSVTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKALVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFPAPKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTPKDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQLKDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFARKANMKGSYSLVEAQKSKV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 81 |
|
|||
| 225 |
|
|||
| 273 | N-linked (GlcNAc...) asparagine | |||
| 365 | N-linked (GlcNAc...) asparagine | |||
| 369 |
|
|||
| 417 | N-linked (GlcNAc...) asparagine | |||
| 463 | N-linked (GlcNAc...) asparagine |
|
||
| 504 |
|
|||
| 531 | N-linked (GlcNAc...) asparagine |
|
||
| 561 | N-linked (GlcNAc...) asparagine |
|
G43417UB
G37881RL
G52527GH
G56784JY
G48414YA
G06356OH
G77669RF
G72747WU
G80075MS
G45395BF
G20706XG
G08918WF
G00912UN
G27058EU
G82830MN
G09831WQ
G94665LC
G30221QT
G81637OR
G65414LI
G50856PC
G01160VV
G39471UU
G05962QB
G70232NH
G55132BD
G69521XL
G35541EV
G93718GY
G75568BH
G57776ZS
G86880BF
G28622IK
G90382BL
G80479JV
G87123QX
G79666IR
G92135MA
G98611JV
G40834TG
G59324HL
G07246CJ
G14972EH
G43223CG
G00273SJ
G70441OD
G87661QW
G83646BJ
G83460ZZ
G41071NU
G80920RR
G42124LM
G62765YT
G31852PQ
G41247ZX
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0040085 | bacterial sepsis | |
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0050167 | autoimmune polyendocrine syndrome type 1 | |
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050773 | paraganglioma | |
| DOID:0050782 | Zollinger-Ellison syndrome | |
| DOID:0050819 | obsolete Matthew-Wood syndrome |
