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Low affinity immunoglobulin gamma Fc region receptor II-b

Summary

UniProt ID

P31994

Gene Symbol

FCGR2B
CD32
FCG2
IGFR2

Organism

Homo sapiens (human)

External Links

GlyGen: P31994
PubChem: P31994

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Chromosomal rearrangement
Disulfide bond
Glycoprotein
Host-virus interaction
IgG-binding protein
Immunoglobulin domain
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Systemic lupus erythematosus
Transmembrane helix

Gene Ontology (GO)

Displaying entries **31 - 40** of 48 in total

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GO Term
negative regulation of B cell receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class II
Fc-gamma receptor signaling pathway
positive regulation of JNK cascade
negative regulation of type I hypersensitivity
negative regulation of acute inflammatory response to antigenic stimulus
receptor-mediated endocytosis
phagocytosis, engulfment
antibody-dependent cellular cytotoxicity
negative regulation of antibody-dependent cellular cytotoxicity

Displaying **all 4** entries
GO Term
external side of plasma membrane
dendritic spine
plasma membrane
cell body

Displaying **all 5** entries
GO Term
protein-containing complex binding
IgG receptor activity
low-affinity IgG receptor activity
IgG binding
amyloid-beta binding

Annotation information from UniProt.

Sequence

MGILSFLPVLATESDWADCKSPQPWGHMLLWTAVLFLAPVAGTPAAPPKAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIVLRCHSWKDKPLVKVTFFQNGKSKKFSRSDPNFSIPQANHSHSGDYHCTGNIGYTLYSSKPVTITVQAPSSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISALPGYPECREMGETLPEKPANPTNPDEADKVGAENTITYSLLMHPDALEEPDDQNRI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	GlyTouCan ID	Source
106	N-linked (GlcNAc...) asparagine		UniProt GlyGen
180	N-linked (GlcNAc...) asparagine		UniProt GlyGen
187	N-linked (GlcNAc...) asparagine		UniProt GlyGen
199			GlyGen
		G62326NX G90093AU G26915XM G17689DH G22310AV G72797UR G63381RX G72667IM G84452RH G96095QD G25520XG G91636VS G93141AZ G70418MS G03382KH G90717TP G23863VK G78059CC G74430RZ G31916IQ G64527OM G23432EQ G72902CL G46687AB G62389NM G82119TF G72291OX G05724UK G29011JC G31936TA G49874UX G80858MF G39188ZX G39213VZ G06110VR G55220VL G60145BJ G96771UL	GlyGen