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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cyclin-dependent kinase inhibitor 2A
Summary
- UniProt ID
- P42771
- Gene Symbol
-
- CDKN2A
- CDKN2
- MTS1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Acetylation
- Alternative splicing
- Cell cycle
- Cytoplasm
- Disease variant
- Li-Fraumeni syndrome
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Tumor suppressor
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| senescence-associated heterochromatin focus |
| nucleus |
| cytoplasm |
| GO Term |
|---|
| cyclin-dependent protein serine/threonine kinase inhibitor activity |
| RNA binding |
| protein kinase binding |
| NF-kappaB binding |
Sequence
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cyclin D associated events in G1 | Homo sapiens |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | Homo sapiens |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | Homo sapiens |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | Homo sapiens |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | Homo sapiens |
| Oncogene Induced Senescence | Homo sapiens |
| Oxidative Stress Induced Senescence | Homo sapiens |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | Homo sapiens |
| Senescence-Associated Secretory Phenotype (SASP) | Homo sapiens |
| Transcriptional Regulation by VENTX | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
