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MIRAGE
Matrix metalloproteinase-9

Summary
UniProt ID
P50282
Gene Symbol
  • Mmp9
Gene ID
81687
Organism
Rattus norvegicus (Norway rat)
PubChem
P50282
Re-Glyco
P50282
Annotation
Keyword
  • Calcium
  • Collagen degradation
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Gene Ontology (GO)
Displaying all 6 entries
GO Term
extracellular space
protein-containing complex
postsynaptic density, intracellular component
Schaffer collateral - CA1 synapse
extracellular matrix of synaptic cleft
glutamatergic synapse
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MSPWQPLLLVLLALGYSFAAPHQRQPTYVVFPRDLKTSNLTDTQLAEDYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFAVWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDRKYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKADGFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRGSKPDPRPPATTAAEPQPTAPPTMCSTAPPMAYPTGGPTVAPTGAPSPGPTGPPTAGPSEAPTESSTPDDNPCNVDVFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDPQPKKIFFFLWAQMWVYTGQSVLGPRSLDKLGLGSEVTLVTGLLPRRGGKALLISRERIWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQDKAYFCHDKYFWRVSFHNRVNQVDHVAYVTYDLLQCP
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
39 N-linked (GlcNAc...) asparagine
121 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Activation of Matrix Metalloproteinases Rattus norvegicus
Assembly of collagen fibrils and other multimeric structures Rattus norvegicus
Collagen degradation Rattus norvegicus
Degradation of the extracellular matrix Rattus norvegicus
EPH-ephrin mediated repulsion of cells Rattus norvegicus
Extra-nuclear estrogen signaling Rattus norvegicus
Neutrophil degranulation Rattus norvegicus
Signaling by SCF-KIT Rattus norvegicus
Disease
Displaying entries 1 - 10 of 12 in total
DO ID Disease Name Source
DOID:0050851 glomerulosclerosis
DOID:1073 renal hypertension
DOID:10941 intracranial aneurysm
DOID:224 transient cerebral ischemia
DOID:2316 brain ischemia
DOID:2349 arteriosclerosis
DOID:5844 myocardial infarction
DOID:6000 congestive heart failure
DOID:6432 pulmonary hypertension
DOID:7693 abdominal aortic aneurysm
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025