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Matrix metalloproteinase-9

Summary

UniProt ID

P50282

Gene Symbol

Mmp9

Gene ID

81687

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P50282
Re-Glyco: P50282

Annotation

Keyword

Calcium
Collagen degradation
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Repeat
Signal
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
extracellular space
protein-containing complex
postsynaptic density, intracellular component
Schaffer collateral - CA1 synapse
extracellular matrix of synaptic cleft
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 53 in total

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GO Term
response to oxidative stress
heart development
response to nutrient
skeletal system development
ossification
response to hypoxia
positive regulation of leukocyte migration
proteolysis
apoptotic process
parturition

Displaying **all 9** entries
GO Term
serine-type endopeptidase activity
zinc ion binding
endopeptidase activity
metalloendopeptidase activity
peptidase activity
metallopeptidase activity
identical protein binding
protein-containing complex binding
fibronectin binding

Annotation information from UniProt.

Sequence

MSPWQPLLLVLLALGYSFAAPHQRQPTYVVFPRDLKTSNLTDTQLAEDYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSETLKAIRSPRCGVPDVGKFQTFDGDLKWHHHNITYWIQSYTEDLPRDVIDDSFARAFAVWSAVTPLTFTRVYGLEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGAVVPTYFGNANGAPCHFPFTFEGRSYLSCTTDGRNDGKPWCGTTADYDTDRKYGFCPSENLYTEHGNGDGKPCVFPFIFEGHSYSACTTKGRSDGYRWCATTANYDQDKADGFCPTRADVTVTGGNSAGEMCVFPFVFLGKQYSTCTSEGRSDGRLWCATTSNFDADKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYHYHEDSPLHEDDIKGIHHLYGRGSKPDPRPPATTAAEPQPTAPPTMCSTAPPMAYPTGGPTVAPTGAPSPGPTGPPTAGPSEAPTESSTPDDNPCNVDVFDAIADIQGALHFFKDGRYWKFSNHGGNQLQGPFLIARTWPAFPSKLNSAFEDPQPKKIFFFLWAQMWVYTGQSVLGPRSLDKLGLGSEVTLVTGLLPRRGGKALLISRERIWKFDLKSQKVDPQSVTRLDNEFSGVPWNSHNVFQYQDKAYFCHDKYFWRVSFHNRVNQVDHVAYVTYDLLQCP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
39	N-linked (GlcNAc...) asparagine			UniProt
121	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Activation of Matrix Metalloproteinases	Rattus norvegicus
Assembly of collagen fibrils and other multimeric structures	Rattus norvegicus
Collagen degradation	Rattus norvegicus
Degradation of the extracellular matrix	Rattus norvegicus
EPH-ephrin mediated repulsion of cells	Rattus norvegicus
Extra-nuclear estrogen signaling	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
Signaling by SCF-KIT	Rattus norvegicus

Disease

Displaying entries **11 - 12** of 12 in total

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DO ID	Disease Name	Source
DOID:850	lung disease	Alliance of Genome Resources
DOID:9477	pulmonary embolism	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements