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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Beta-2-microglobulin
Summary
- UniProt ID
- P61769
- Gene Symbol
-
- B2M
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Amyloid
- Amyloidosis
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycation
- Immunoglobulin domain
- MHC I
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| protein refolding |
| cellular response to iron(III) ion |
| cellular response to nicotine |
| positive regulation of ferrous iron binding |
| positive regulation of transferrin receptor binding |
| amyloid fibril formation |
| GO Term |
|---|
| focal adhesion |
| external side of plasma membrane |
| ER to Golgi transport vesicle membrane |
| specific granule lumen |
| MHC class I protein complex |
| GO Term |
|---|
| MHC class II protein complex binding |
| identical protein binding |
| protein homodimerization activity |
| structural molecule activity |
| peptide antigen binding |
Sequence
MSRSVALAVLALLSLSGLEAIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 | N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis |
|
||
| 39 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 61 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 68 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 72 |
|
|||
| 75 |
|
|||
| 77 |
|
|||
| 78 | N-linked (Glc) (glycation) lysine; in vitro |
|
||
| 102 |
|
|||
| 106 |
|
G49108TO
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amyloid fiber formation | Homo sapiens |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | Homo sapiens |
| DAP12 interactions | Homo sapiens |
| DAP12 signaling | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| Endosomal/Vacuolar pathway | Homo sapiens |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Modulation by Mtb of host immune system | Homo sapiens |
| Nef mediated downregulation of MHC class I complex cell surface expression | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
