Histone-lysine N-methyltransferase EZH2

Summary
UniProt ID
Q61188
Gene Symbol
  • Ezh2
  • Enx1h
Organism
Mus musculus (house mouse)
GlyGen
Q61188
PubChem
Q61188
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Biological rhythms
  • Chromatin regulator
  • Chromosome
  • Glycoprotein
  • Isopeptide bond
  • Methyltransferase
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Repressor
  • S-adenosyl-L-methionine
  • Transcription regulation
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKTMFSSNRQKILERTETLNQEWKQRRIQPVHIMTSVSSLRGTRECSVTSDLDFPAQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPDEREEKQKDLEDNRDDKETCPPRKFPADKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTISVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPVPTEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
75 O-linked (GlcNAc) serine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Oxidative Stress Induced Senescence Mus musculus
PKMTs methylate histone lysines Mus musculus
PRC2 methylates histones and DNA Mus musculus
Transcriptional Regulation by E2F6 Mus musculus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024