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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Proheparin-binding EGF-like growth factor
Summary
- UniProt ID
- Q99075
- Gene Symbol
-
- HBEGF
- DTR
- DTS
- HEGFL
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- Q99075
- PubChem
- Q99075
- The Human Metabolome Database
- HMDBP02701
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Heparin-binding
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell surface |
| extracellular region |
| extracellular space |
| plasma membrane |
| endocytic vesicle membrane |
| clathrin-coated endocytic vesicle membrane |
Sequence
MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKVRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGMTNSH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 32 |
|
|||
| 37 | O-linked (GalNAc...) threonine | |||
| 38 | O-linked (GalNAc...) serine |
|
||
| 44 | O-linked (GalNAc...) threonine | |||
| 46 |
|
|||
| 47 | O-linked (GalNAc...) threonine | |||
| 74 |
|
|||
| 75 | O-linked (GalNAc...) threonine | |||
| 77 |
|
|||
| 78 |
|
G57321FI
G53434XO
G48584BU
G29931IJ
G43417UB
G50757KG
G81006GJ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PTK6 promotes HIF1A stabilization | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| SHC1 events in EGFR signaling | Homo sapiens |
| SHC1 events in ERBB2 signaling | Homo sapiens |
| SHC1 events in ERBB4 signaling | Homo sapiens |
| Signaling by EGFR | Homo sapiens |
| Signaling by ERBB2 | Homo sapiens |
| Signaling by ERBB2 KD Mutants | Homo sapiens |
| Signaling by ERBB2 TMD/JMD mutants | Homo sapiens |
| Signaling by ERBB4 | Homo sapiens |
