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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibrinogen alpha chain
Summary
- UniProt ID
- P02671
- Gene Symbol
-
- FGA
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011303
- GlyConnect
- GlyGen
- P02671
- PubChem
- P02671
- The Human Metabolome Database
- HMDBP13512
- RaftProt
- P02671
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Amyloid
- Amyloidosis
- Blood coagulation
- Calcium
- Coiled coil
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydroxylation
- Innate immunity
- Isopeptide bond
- Metal-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
| GO Term |
|---|
| endoplasmic reticulum lumen |
| external side of plasma membrane |
| cell surface |
| blood microparticle |
| GO Term |
|---|
| signaling receptor binding |
| metal ion binding |
| structural molecule activity |
| extracellular matrix structural constituent |
Sequence
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amyloid fiber formation | Homo sapiens |
| Common Pathway of Fibrin Clot Formation | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Homo sapiens |
| IRAK4 deficiency (TLR2/4) | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Integrin signaling | Homo sapiens |
| MAP2K and MAPK activation | Homo sapiens |
| MyD88 deficiency (TLR2/4) | Homo sapiens |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | Homo sapiens |
