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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Receptor tyrosine-protein kinase erbB-2
Summary
- UniProt ID
- P04626
- Gene Symbol
-
- ERBB2
- HER2
- MLN19
- NEU
- NGL
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011368
- GlyConnect
- GlyGen
- P04626
- PubChem
- P04626
- The Human Metabolome Database
- HMDBP01473
- RaftProt
- P04626
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Activator
- Alternative initiation
- Alternative splicing
- Cell membrane
- Cell projection
- Chromosomal rearrangement
- Cytoplasm
- Disease variant
- Disulfide bond
- Endosome
- Glycoprotein
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Signal
- Transcription regulation
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| membrane |
| neuromuscular junction |
| myelin sheath |
| receptor complex |
| basolateral plasma membrane |
| apical plasma membrane |
| cytosol |
| semaphorin receptor complex |
Sequence
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Resistance of ERBB2 KD mutants to sapitinib | Homo sapiens |
| Resistance of ERBB2 KD mutants to tesevatinib | Homo sapiens |
| Resistance of ERBB2 KD mutants to trastuzumab | Homo sapiens |
| SHC1 events in ERBB2 signaling | Homo sapiens |
| Sema4D induced cell migration and growth-cone collapse | Homo sapiens |
| Signaling by ERBB2 | Homo sapiens |
| Signaling by ERBB2 ECD mutants | Homo sapiens |
| Signaling by ERBB2 KD Mutants | Homo sapiens |
| Signaling by ERBB2 TMD/JMD mutants | Homo sapiens |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | Homo sapiens |
