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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
HLA class I histocompatibility antigen, C alpha chain
Summary
- UniProt ID
- P10321
- Gene Symbol
-
- HLA-C
- HLAC
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Host-virus interaction
- Innate immunity
- MHC I
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| secretory granule membrane |
| external side of plasma membrane |
| cell surface |
| ER to Golgi transport vesicle membrane |
| MHC class I protein complex |
| lumenal side of endoplasmic reticulum membrane |
| GO Term |
|---|
| TAP binding |
| peptide antigen binding |
| signaling receptor binding |
Sequence
MRVMAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | Homo sapiens |
| DAP12 interactions | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| Endosomal/Vacuolar pathway | Homo sapiens |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Interferon alpha/beta signaling | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
