GlyCosmos Portal

Xenopus tropicalis (tropical clawed frog)

Summary

Taxonomy ID: 8364
PubChem Taxonomy: 8364

Genes (459) Glycans (10) Glycoproteins (269) Lectins (10) Pathways (156)

Displaying entries **1 - 25** of **156** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Metal ion SLC transporters	Copper transport protein Natural resistance-associated macrophage protein 1 Natural resistance-associated macrophage protein 2 isoform X1 Solute carrier family 30 member 10 Solute carrier family 40 member Solute carrier family 41 member ferroxidase ferroxidase	A0A6I8Q1B1 A0A6I8QQZ6 A0A6I8QTJ5 A0A803KEV8 A0A803KGX9 B4F6L7 F7E7W6 Q6NVQ3	IREG1 Xctr1 copt1 cp ctr1 dct-1 dct1 dmt1 fpn1 hctr1 hephl1 mtp1 nramp2 slc11a1 slc11a2 slc11a3 slc30a10 slc31a1 slc39a1 slc40a1 slc41a1-l1 slc41a2
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Igf2 protein Insulin like growth factor 1 Insulin like growth factor 2 Tyrosine-protein kinase receptor	A0A6I8RT94 A0A803K087 A9JSC3 F6U172 F6V1C3	IGF-II cilp igf-2 igf1 igf1r igf2 igf2-a igf2-b insigf pp9974
Signal transduction by L1	Fibroblast growth factor receptor Integrin alpha-5 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V isoform X1 Integrin beta Integrin beta Neural cell adhesion molecule 2 Neuropilin Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase non-specific serine/threonine protein kinase	A0A6I8Q5U0 A0A6I8QC93 A0A6I8QUX8 A0A6I8S833 A0A6I8ST12 A0A6I8T2M0 A4III3 F6T2D3 F6U9K9 F6UFM4 Q28J96 Q6GL60	Rac1 X1FGFR XFGFR-1 Xrac bfgfr cd29 cd304 cd331 cd51 cek egfr fgfbr fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 fnrb gpiia hbgfr itga2b.1 itga2b.2 itga5 itga9 itgav itgav-a itgav-b itgb1 itgb1-a itgb1-b itgb3 kal2 mdf2 mig5 msk12 msk8 n-sam ncam2 ncam21 neuropilin np-1 npn-1 nrp nrp-1 nrp1 ogd p21-rac1 pNPG152 pak1 rac rac1 tc-25 vegf165r vla-beta vlab vnra xfgfr1
Role of phospholipids in phagocytosis	5'-3' exonuclease PLD3 LOC100158576 protein Phospholipase Phospholipase Phospholipid phosphatase 4 Protein kinase C delta type phospholipase A2	A0A6I8QZC1 A0A6I8RHC7 A0A6I8SIW5 B2GUF2 F7AE83 F7DKY7 Q640B3	LOC100158576 pla2g6 pld1 pld2 pld3 plpp4 plpp5 ppapdc1b prkcd
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 Alpha-2-macroglobulin-like 1 pseudogene Alpha-2-macroglobulin Alpha-2-macroglobulin Basigin Brevican core protein Calpain 14 Calpain 7 Calpain 8 gene 5 Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-13 Calpain-2 catalytic subunit Calpain-3 Calpain-5 Calpain-6 Calpain-9 Cathepsin G Cathepsin S Collagenase 3-like Collagenase 3 Collagenase 3 MGC89057 protein Matrix metallopeptidase 11 Matrix metallopeptidase 14 (Membrane-inserted) Matrix metallopeptidase 19 Matrix metallopeptidase 1 Matrix metallopeptidase 20 Matrix metallopeptidase 3 precursor Matrix metalloproteinase-18 Matrix metalloproteinase-9 Opticin Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1 interstitial collagenase	A0A6I8PU05 A0A6I8PVU9 A0A6I8PY14 A0A6I8QBM5 A0A6I8QT93 A0A6I8QUP1 A0A6I8R102 A0A6I8RC49 A0A6I8RND2 A0A6I8RP28 A0A6I8S643 A0A6I8SPW3 A0A803JT32 A0A803K4H8 A0A803KC39 A9UMJ1 B2GUG2 F6SRT1 F6TCS3 F6TCT8 F6TVV1 F6Y400 F6YLX6 F7B862 F7DI46 Q28FK8 Q28HP1 Q28IS0 Q28J86 Q4QQQ9 Q5BL52 Q5FVW8 Q66IH0 Q66JI2 Q6DF35 Q6DIP0	CAPN1 CD147 LOC100135369 LOC100158582 LOC100489060 LOC100489108 LOC100491214 LOC100491547 LOC100495980 LOC101731595 LOC101731804 LOC116408897 MGC89057 MMP-14 MMP-18 MMP7 MMP8 MT-MMP-1 Xmmp2 a2m adamts4 adamts5 bcan bsg calpb canp canpl1 capn1 capn11 capn13 capn14 capn3 capn5 capn6 capn7 capn8.5 capn9 capns1 capns2 chds6 clg clg3 clg4 clg4a clgn col3 col4 ctsg ctss ctss-a ctss-b ctss.1 htra3 mandp1 matrilysin mgc108008 mmp-3 mmp-7 mmp-ii mmp-x1 mmp1 mmp10 mmp11 mmp13 mmp13l mmp14 mmp18 mmp19 mmp2 mmp20 mmp3 mmp7 mmp8 mmp9.1 mmp9.2 mona mt1-mmp mtmmp1 mucanp mucl ncl-3 optc ovos2 pump-1 pzp scube1 sl-1 stmy stmy1 str1 tbe-1 xcol4
Glycosphingolipid catabolism	Arylsulfatase A Arylsulfatase D Arylsulfatase G Arylsulfatase I Arylsulfatase J Arylsulfatase K Beta-galactosidase-1-like protein precursor Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Cation-dependent mannose-6-phosphate receptor isoform X1 Ectonucleotidase enpp7 GM2 ganglioside activator protein Neutral ceramidase Sphingomyelin phosphodiesterase Steroid sulfatase Sulfatase-modifying factor 1 exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase	A0A1B8XW41 A0A6I8PLI9 A0A6I8QCM2 A0A6I8QNF3 A0A6I8RIF4 A0A7D9N0G1 A0A7D9N0J1 B1H351 B3DM04 B7ZUC6 F6ZR01 F7BUA3 F7EJM6 K0PUS8 K0PUT3 Q28E48 Q28H18 Q5FW01 Q5XHB8 Q66IJ9	LOC100145556 LOC100170585 LOC548706 MGC107931 MGC89423 arsa.1 arsd arsg arsi arsj arsk asah2 enc-1as enpp7 fge glb1 glb1l glb1l2 gm2a hexb m6pr neu3 neu3.1 neu4 sial3 smpd1 smpd3 sts sumf1	G09546QO G27025MB
Activated NOTCH1 Transmits Signal to the Nucleus	E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Neurogenic locus notch homolog protein 1 Novel protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A6I8SBZ2 A0JM32 A2RUV0 F6TZH9 F7CWT1 Q28FM7 Q6AZL4 Q6GL58	LOC100216108 LOC548926 MGC89679 RPS27A aif4 aip4 cep52 dtx1 dtx2 dtx4 hmg20 hubcep52 itch itchy napp1 notch1 rpl40 rps27a uba52 ubc ubi-p63e
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor (Fragment) Inositol 1,4,5-trisphosphate receptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	A0A6I8RGU0 A0A6I8RW96 A0A6I8SDW5 A0A6I8SK99 A0A803JVP3 A4ZYX8 F6V4A4	itpr2 itpr3 p2rx1 p2rx4 p2rx5 trpc3 trpc6
Collagen chain trimerization	Collagen alpha-1(I) chain precursor Collagen alpha-1(II) chain Collagen alpha-1(III) chain precursor Collagen alpha-1(IX) chain isoform X1 Collagen alpha-1(V) chain isoform X2 Collagen alpha-1(VII) chain isoform X1 Collagen alpha-1(XII) chain isoform X1 Collagen alpha-1(XIX) chain isoform X1 Collagen alpha-1(XVII) chain isoform X1 Collagen alpha-1(XX) chain isoform X1 Collagen alpha-1(XXVII) chain isoform X1 Collagen alpha-2(I) chain precursor Collagen alpha-2(IX) chain precursor Collagen alpha-2(V) chain Collagen alpha-3(IX) chain precursor Collagen alpha-3(V) chain isoform X1	A0A6I8SFH9 A0A6I8SQF8 A0A6I8SQU0 A0A6I8T0Y5 A0A803J8Y6 A0A803JG94 A0A803K045 A0A803KF91 A0JM00 A0JP88 B1H3F6 B5DES3 F6QGI3 F7AU67 Q640B2 Q6P4Z2	LOC100036633 LOC100145619 LOC100497990 LOC496414 col12a1 col17a1 col19a1 col1a1 col1a2 col20a1 col27a1 col2a1 col3a1 col5a1 col5a2 col7a1 col9a1 col9a2 col9a3 oi4 otol1
NOTCH3 Activation and Transmission of Signal to the Nucleus	E3 ubiquitin-protein ligase Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 LOC100127663 protein Neurogenic locus notch homolog protein 1 Nicastrin Novel protein Presenilin Presenilin Receptor protein-tyrosine kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A6I8PML7 A0A803K579 A0A803KJM5 A2RUV0 A8KBG4 F6UFM4 F6VJY6 F7C949 Q28FM7 Q28GF7 Q6AZL4 Q6GL58	LOC100127663 LOC100216108 LOC548926 MGC89679 RPS27A X-PS-alpha X-PS-beta X-ps-a X-ps-b ad3 ad3l ad4 aip2 aph-1a aph1a cep52 cgi-78 egf egfr fad hmg20 hubcep52 mds033 mstp064 ncstn notch1 pen-2 pen2 ps-a ps-alpha ps-b ps-beta ps1 ps2 psen1 psen2 psenen rgd1312037 rpl40 rps27a s182 stm2 uba52 ubc ubi-p63e wwp2 wwp2-like xegf
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A6I8PM12 A0A6I8SJT2 A0A803K518 Q28J96	X1FGFR XFGFR-1 bfgfr cd331 cek fgf23 fgf23.1 fgf23.2 fgfbr fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 hbgfr kal2 kl n-sam ogd xfgfr1
Acyl chain remodelling of PC	Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophosphatidylcholine acyltransferase 1 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase LPCAT4 Phospholipase A and acyltransferase 3 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor lysoplasmalogenase lysoplasmalogenase phospholipase A2 phospholipase A2	A0A6I8PMU8 A0A803K0T6 A0A803K1C6 A0A803KFH5 A4IIH1 A9UMH3 B0BMQ4 B1H311 B1WAZ6 F6PVH0 F6S3K0 F6TFZ5 F6VH26 F7AE83 Q28C60 Q28GM9	LOC100135356 LOC100145092 LOC100145529 LOC116407767 agpat7 aytl3 cpla2 lpcat1 lpcat4 mboat1 mboat2 oact2 pla2 pla2a pla2g12a pla2g1b pla2g1bl pla2g2d pla2g3 pla2g4 pla2g4a pla2g4f pla2g6 pla2r1 plaat4 ppla2 tmem86a tmem86b
Keratan sulfate degradation	Beta-galactosidase-1-like protein precursor Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Fibromodulin Lumican N-acetylglucosamine-6-sulfatase Osteomodulin Prelp protein	A0A6I8PLI9 A0A6I8SFJ2 A4IIL0 A9JRM2 B1H351 F6RIJ3 Q28E48 Q5XHB8 Q640B1	LOC100135105 LOC100145556 enc-1as fmod glb1 glb1l glb1l2 gns hexb ldc lum omd prelp slrr2d	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Frizzled class receptor 3 Frizzled class receptor 5 Frizzled-2 Frizzled-4 Guanine nucleotide binding protein (G protein), beta polypeptide 4 Guanine nucleotide binding protein, beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Mitogen-activated protein kinase kinase kinase 7 Mitogen-activated protein kinase Phosphodiesterase Phosphodiesterase Protein Wnt-11 Protein Wnt calcium/calmodulin-dependent protein kinase	A0A6I8PNV7 A0A6I8QRN7 A0A6I8QTD1 A0A6I8R459 A0A6I8RCH1 A0A6I8SDL6 A0A6I8SFN9 A0A6I8SIM1 A0A6I8T213 A0A803K619 A0A803KBZ4 A0A803KFL6 A4IGZ2 A4IIB5 A4QNP4 B0JZD9 B2GUT4 B3DLW1 F6VSL4 F7AZL7 F7EBE7 Q05B33 Q0VFL5 Q28G20 Q28H40 Q5XGD8 Q66KA3 Q6DF33	Fz-2 Fz-3 Go LOC100038286 LOC100124978 LOC733883 MAPKKK MGC145965 XGB1 XGalpha01 XGbeta1 Xfz2 Xfz3 Xnlk camk2 camk2a camkII camka frizzled-2 frizzled-3 frizzled2 frizzled3 frz-3 frz3 fz2 fz3 fzd2 fzd3 fzd4 fzd5 g-alpha-o g0a g0alpha ga0 gao gnao gnao1 gnb1 gnb2 gnb3 gnb4 gnb5 gng10 gng12 gng2 gng3 gng4 gng7 gng7-a gng7-b gngt1 gngt2.1 hfz3 map3k7 nlk nlk1 pde6a pde6b pi-plc plc-154 plc-i plc154 plcb1 plcb2 plcb3 tak1 wnt11 wnt11r wnt5a xTAK1
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	26S protease regulatory subunit 4 Autocrine motility factor receptor Derlin Novel protein Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Transitional endoplasmic reticulum ATPase UBX domain-containing protein 1 UV excision repair protein RAD23 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A6I8Q741 A0A7D9NLE4 F7A2H2 Q28BX4 Q28FM7 Q28GC0 Q28J46 Q6AZL4 Q6GL04 Q6GL58 Q6GL77	LOC100216108 LOC548926 MGC89679 RPS27A amfr cep52 derl1 engase gp78 hmg20 hubcep52 ngly1 p26s4 p56 pros26.4 psmc1 rad23b rnf45 rpl40 rps27a saks1 uba52 ubc ubi-p63e ubxn1 vcp	G03934XO G25577BM G28233ME G51034LA G86419OL
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Klotho Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1	A0A6I8PM12 A0A6I8QQS1 A0A6I8SJT2 A0A803J293 A0A803K518 A0A803KIA6 B7U3X7 B7U3X8 B7UC02 B7ZSQ9 F6XSB5 F6ZB49 Q28DZ3 Q28J96 Q66IF7 Q66II3	FGF-8 HBGF-1 HBGF-2 HBGF-4 INT-2 X1FGFR XEFGF XFGFR-1 Xfgf-4 Xfgf-8 Xfgf4 Xfgf8 aFGF aigf bfgf bfgfr cd331 cek ecgf ecgf-beta ecgfa ecgfb efgf fgf-1 fgf-10 fgf-2 fgf-3 fgf-4 fgf-6 fgf-8b fgf-alpha fgf1 fgf10 fgf2 fgf22 fgf23 fgf23.1 fgf23.2 fgf3 fgf4 fgf4-a fgf4-b fgf5 fgf6 fgf8 fgf8a fgf8b fgf9 fgfa fgfb fgfbr fgfe fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 glio703 grb2 hbgf-3 hbgf-6 hbgf-8 hbgf1 hbgfr hbgh-2 hst hst-1 hst2 hstf1 int2 k-fgf kal2 kfgf kl n-sam ogd sos1 xfgf2 xfgf3 xfgfr1
Integrin cell surface interactions	Basigin Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain isoform X1 Collagen alpha-1(XXVII) chain isoform X1 Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain precursor Collagen alpha-3(IX) chain precursor Fibronectin Integrin alpha-10 Integrin alpha-11 Integrin alpha-1 Integrin alpha-2 Integrin alpha-3 Integrin alpha-4 Integrin alpha-5 Integrin alpha-6 isoform X1 Integrin alpha-8 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V isoform X1 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Junctional adhesion molecule 2 Junctional adhesion molecule 3 Lumican Mucosal addressin cell adhesion molecule 1 Tenascin C Thrombospondin-1 Vitronectin precursor (Fragment)	A0A6I8PVE3 A0A6I8PVU9 A0A6I8PZ36 A0A6I8Q579 A0A6I8Q5U0 A0A6I8Q7J4 A0A6I8Q8C8 A0A6I8QC93 A0A6I8QRY8 A0A6I8QUX8 A0A6I8R917 A0A6I8RQ44 A0A6I8RXA9 A0A6I8S833 A0A6I8SH64 A0A6I8SQA4 A0A6I8ST12 A0A6I8T0K9 A0A6I8T0Y5 A0A803JXA8 A0A803K8M1 A0A803KF91 A0JP88 A4IGI8 A4IHE8 B1H3F6 B5DEV6 F6Q166 F6TF09 F6U9K9 F7B2H7 Q0VFK4 Q501R6 Q640B1	CD147 FN LOC100036633 LOC100037861 LOC100145619 bsg cd29 cd322 cd51 cig col27a1 col4a1 col4a2 col9a1 col9a2 col9a3 comp fibronectin finc fn1 fnrb gpiia itga1 itga10 itga11 itga2 itga2b.1 itga2b.2 itga3 itga4 itga5 itga6 itga8 itga9 itgav itgav-a itgav-b itgb1 itgb1-a itgb1-b itgb3 itgb5 itgb6 itgb7 itgb8 jam-b jam2 jam3 jamb ldc lets lum madcam1 mdf2 msf msk12 msk8 pro245 slrr2d thbs1 tnc ve-jam vejam vla-beta vlab vnra vtn xbx6
Gluconeogenesis	Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphate exchanger SLC37A1 Glucose-6-phosphate exchanger SLC37A2 Glucose-6-phosphate exchanger SLC37A4 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate mutase Phosphoglycerate mutase Triosephosphate isomerase phosphopyruvate hydratase	A0A803JVX2 A0A803KGI3 B0BM04 B0BM20 B0BM40 F6VZ50 F6ZHL4 F6ZRC3 F7BX58 Q28DY9 Q28HJ8 Q4VA70 Q501L0 Q5M7K3 Q6GL64 Q6NVQ9 Q6P7Y9 Q6P8F7	LOC100125173 LOC100144939 LOC733907 MGC69434 MGC75708 MGC76327 aldb aldo2 aldoa aldob aldoc amf eno1 eno1-a eno1-b eno1l1 eno3 eno4 fbp1 fbp2 g3pd g6pc g6pc.1 g6pc1 g6pc1.1 g6pc2 g6pt1 g6pt2 g6pt3 gapd gapdh gnpi gpi gsd13 gsd1b gsd1c gsd1d igrp mbp-1 mgc108013 mgc108129 mpb1 mse nlk nne pck1 pepck-c pepck1 pepckc pgam1 pgam2 pgi phi pph pro0685 sa-36 slc37a1 slc37a2 slc37a4 tpi tpi1 trg19 xaldb	G58161NS
Hedgehog 'on' state	26S protease regulatory subunit 10B 26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division cycle 73 Cullin-3 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Ellis van Creveld syndrome 2 Ellis-van Creveld syndrome protein G-protein coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Novel protein Numb homolog (Drosophila) Patched 1 Proteasomal ubiquitin receptor ADRM1 Proteasome 26S non-ATPase subunit 12 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Protein smoothened Speckle-type POZ protein-like Speckle-type POZ protein Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein cullin-RING-type E3 NEDD8 transferase	A0A1B8Y9B4 A0A6I8PYJ0 A0A6I8QGB6 A0A6I8RCT3 A0A6I8RDQ3 A0A6I8RRT2 A0A6I8S8I3 A0A6I8SVL3 A0A803JPT9 A0A803JRJ1 A0A803KJS7 A0JM32 A4IH32 A4IHP4 A4IHT1 B3DLW7 B3DM66 F6V904 F6VJR0 F6VLC5 F6WGT0 F6XBL2 F6ZSY4 F7DZP4 Q07FY6 Q28BX4 Q28FM7 Q28GV0 Q5BKG2 Q5EB37 Q5PPP6 Q5XH87 Q642N1 Q66JJ6 Q66JK8 Q6AZL4 Q6DIE6 Q6GL58 Q6P2Y7 Q6P307 Q6P380 Q6P7K3 Q6P7Z3 Q6P877 Q6P8B3 Q6P8E4 Q6P8E6	LOC100124849 LOC100216108 LOC496467 LOC548926 LOC549136 MGC75584 MGC76296 MGC76321 MGC89679 MGC90008 MGC97603 Psmc2 Psmc4 Psmd7 RPS27A TBP10 XC3 XSUG1 XTBP10 Xsufu adrm1 aif4 aip4 cadp44 cdc73 cep52 cul3 dwf-1 evc evc2 evcl gli1 gli2 gli3 gpr161 hip6 hmg20 hrpt2 hspc hubcep52 hypf itch itchy napp1 nin1p numb p26s4 p44s10 p56 pro1280 pros26.4 pros30 psma1 psma2 psma3 psma4 psma5 psma6 psma7 psma7-a psma7-b psmb1 psmb2 psmc1 psmc2 psmc3 psmc4 psmc5 psmc6 psmd1 psmd11 psmd12 psmd13 psmd14 psmd2 psmd3 psmd6 psmd7 psmd8 psmd8-a psmd8-b ptch1 rbx1 rc6-1 rpl40 rpn12 rpn5 rpn7 rps27a rpt3 s10 s171 smo smurf1 smurf2 spop spopl sufu sufuh sufuxl sug-1 sug1 sug2 tbp10 uba52 ubc ubi-p63e xapc7
Lysosphingolipid and LPA receptors	LOC100124893 protein LOC100145312 protein LOC100145694 protein LPA2 protein Lysophosphatidic acid receptor 3 Phospholipid phosphatase-related 4 Phospholipid phosphatase-related protein type 1 Sphingosine 1-phosphate receptor 1 Sphingosine 1-phosphate receptor 2 Sphingosine 1-phosphate receptor 3 Sphingosine 1-phosphate receptor 4	A0A803J364 A0A803J812 A0A803J917 A0A803JDI8 A0A803K6E2 A4IHT5 A4II83 B1H174 B1WAQ2 F6Y7C0 Q68PF6	EDG4 LOC100124893 LOC100145312 LOC100145694 LPA2 MGC147427 edg-2 edg-8 edg2 edg8 gpr26 lpa1 lpa1r lpa1r1 lpa2 lpar1 lpar1-a lpar1-b lpar2 lpar3 lppr1 lppr3 lpr3 plppr1 plppr3 plppr4 prg-2 prg2 s1p1 s1p5 s1pr1 s1pr2 s1pr3 s1pr4 s1pr5 sppr-1 sppr-2 vzg-1 vzg1 xts1p1 xts1p5
Platelet degranulation	Actin, cytoplasmic 1 Actinin alpha 2 Albumin precursor Alpha-2-HS-glycoprotein Alpha-2-macroglobulin-like 1 pseudogene Alpha-2-macroglobulin Alpha-2-macroglobulin Alpha-actinin-4 Amyloid-beta A4 protein Annexin Arginine-rich, mutated in early stage tumors Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 CD109 antigen CYFIP related Rac1 interactor B Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor XIII A chain Endonuclease domain containing 1 Extracellular matrix protein 1 FERM domain-containing kindlin 3 Fibronectin Filamin-A Fructose-bisphosphate aldolase GTP-binding protein 2 Gas6 protein Hepatocyte growth factor Histidine-rich glycoprotein Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan-binding protein 4 Igf2 protein Insulin like growth factor 1 Insulin like growth factor 2 Integrin alpha-IIb Integrin beta Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen-1 LHFPL tetraspan subfamily member 2 LOC100127663 protein Left-right determination factor MICOS complex subunit Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 Multimerin-1 NHL repeat containing 2 NSE3 homolog, SMC5-SMC6 complex component Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet glycoprotein 4 Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Protein FAM3C Protocadherin 7 Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secretogranin-3 Serine (Or cysteine) peptidase inhibitor, clade A, member 3M precursor Serine (Or cysteine) proteinase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 1 Serine protease ami Serotransferrin Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Synaptotagmin-like 4 Syntaxin-binding protein 2 Talin 1 Tetraspanin Tetraspanin Thrombospondin-1 Thymosin beta Torsin-4A Transforming growth factor beta Transforming growth factor beta Transgelin Tubulin alpha chain Tubulin alpha chain Vascular endothelial growth factor A precursor Vascular endothelial growth factor B Vascular endothelial growth factor D Vesicle transport through interaction with t-SNAREs homolog 1B Vitamin K-dependent protein S WD repeat-containing protein 1 von Willebrand factor	A0A1B8Y3D5 A0A1B8Y922 A0A6I8PMF1 A0A6I8PW60 A0A6I8PY35 A0A6I8Q175 A0A6I8Q5U0 A0A6I8QA50 A0A6I8QAK5 A0A6I8QG67 A0A6I8QHB5 A0A6I8QSC0 A0A6I8QU02 A0A6I8QUX8 A0A6I8R415 A0A6I8R680 A0A6I8RDQ6 A0A6I8RHF2 A0A6I8RJ91 A0A6I8RQ44 A0A6I8S0H0 A0A6I8S1X2 A0A6I8S7R2 A0A6I8SG02 A0A6I8SKR5 A0A7D9NLR4 A0A803J4P1 A0A803J8P5 A0A803JQP9 A0A803JRQ1 A0A803K087 A0A803K8T7 A0A803KGC2 A0A803KLS9 A0JLZ2 A8KBG4 A9JSC3 A9JSD8 B0BLS9 B0BMQ3 B1H1E3 B2GUS2 B3DLA0 B5DDZ6 B7ZTI5 F6QTY9 F6RAJ4 F6RNU6 F6TCS3 F6TCT8 F6U272 F6V1C3 F6YXP5 F7A485 F7AK89 F7DI46 F7E728 Q0IIW3 Q28E66 Q28EH0 Q28EW7 Q28F45 Q28GI4 Q28H14 Q28HY7 Q28IX8 Q501K5 Q501R6 Q504L9 Q5BKJ7 Q5BL93 Q5CZZ1 Q5M8J9 Q5M8K2 Q640T3 Q66IL0 Q66JG0 Q6DF05 Q6DIF4 Q6DIX4 Q6DJA6 Q6DJB6 Q6GL64 Q6GLH1 Q6NVA9 Q6P2X6 Q6P326 Q6P376	3e46 FN IGF-II LOC100127663 LOC100135142 LOC100170470 LOC100489060 LOC101730484 LOC549743 LOC733468 LOC733989 LOC779492 MGC69493 MGC75598 MGC89158 MGC89163 TIMP1 XATV Xlefty a2hs a2m aaa abeta abpp actb actn2 actn4 ad1 ahs ahsg aip1 alb alb-a alb-b aldoa ami antivin anx5 anxa5 apoh apool app appi armet arp atp6v0b-prov atv axllg axsf bh-pcdh bhpcdh brpf3 c-sis cd109 cd36 cd63 cd9 cdc37l1 chid1 cig clu ctfgamma ctsw cvap cyrib ecm1 egf endod1 enx2 f13a1 f8vwf fam3c fam49b fat fermt3 fetua fibronectin finc flna fn1 fsgs fsgs1 gas6 gp3b gp4 gpiv gtpbp2 habp4 hca4 hgf hrg hsga igf-2 igf1 igf2 igf2-a igf2-b ihabp4 insigf itga2b.1 itga2b.2 itgb3 itih4 ki-1/57 kind3 kindlin3 kng1 leftb lefty lefty-1 lefty-a lefty-b lefty1 leftyb lets lhfpl2 magee1 mageg1 magel3 manf mgc69493 mmcm7 mmrn1 msf ndnl2 nfpc nhlrc2 nse3 nsmce3 ociad2 ola1 ovos2 p47 pasiv pcdh7 pcyox1l pdgf2 pdgfb phactr2 plek plg pn2 pp9974 pros1 ptmb4 pzp qsox1 rarres2 scarb3 sccpdh scg3 serbp1l serpina1 serpina3 serpina3m serpine1 sis sm22-a sm22-alpha sod1 sparc spi-2l spi2 spi2.4 stxbp1 stxbp2 sytl4 tagln2 tf tgfb1 tgfb2 thbs1 timp-1 timp1 timp3 tln1 tmsb4 tmsb4x tor4a tuba tuba1 tuba4 tuba4a tuba4b vefg vegf vegf-a vegfa vegfa-a vegfa-b vegfb vegfd vpf vti1b vwd vwf wdr1 xclu xegf
Negative regulation of FGFR1 signaling	Anosmin 1 Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Klotho Mitogen-activated protein kinase Multifunctional fusion protein Novel protein Tyrosine-protein phosphatase non-receptor type Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A6I8PM12 A0A6I8SAV8 A0A6I8SJT2 A0A803J293 A0A803K518 A0A803KIA6 A9JRI8 B5DE89 B7U3X7 B7U3X8 B7UC02 B7ZSQ9 F6XSB5 F6ZB49 Q28DZ3 Q28FM7 Q28H11 Q28J96 Q66IF7 Q66II3 Q6AZL4 Q6GL58	FGF-8 HBGF-1 HBGF-2 HBGF-4 INT-2 LOC100216108 LOC548926 MGC89679 RPS27A X1FGFR XEFGF XFGFR-1 XSNT Xfgf-4 Xfgf-8 Xfgf4 Xfgf8 aFGF admlx aigf anos1 bfgf bfgfr cd331 cek cep52 ecgf ecgf-beta ecgfa ecgfb efgf erk erk2 ert1 fgf-1 fgf-10 fgf-2 fgf-3 fgf-4 fgf-6 fgf-8b fgf-alpha fgf1 fgf10 fgf2 fgf22 fgf23 fgf23.1 fgf23.2 fgf3 fgf4 fgf4-a fgf4-b fgf5 fgf6 fgf8 fgf8a fgf8b fgf9 fgfa fgfb fgfbr fgfe fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 frs2 frs2a frs2alpha glio703 grb2 hbgf-3 hbgf-6 hbgf-8 hbgf1 hbgfr hbgh-2 hha hmg20 hst hst-1 hst2 hstf1 hubcep52 int2 k-fgf kal kal1 kal2 kalig-1 kfgf kl kms mapk mapk1 mapk1-a mapk1-b mapk2 mpk1 n-sam ogd p38 p40 p41 p41mapk p42mapk prkm1 prkm2 ptpn11 rpl40 rps27a snt snt-1 snt1 uba52 ubc ubi-p63e xfgf2 xfgf3 xfgfr1 xfrs2 xp42 xsrf2
Collagen biosynthesis and modifying enzymes	A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1 A disintegrin and metalloproteinase with thrombospondin motifs 3 Collagen alpha-1(I) chain precursor Collagen alpha-1(II) chain Collagen alpha-1(III) chain precursor Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain isoform X1 Collagen alpha-1(V) chain isoform X2 Collagen alpha-1(VII) chain isoform X1 Collagen alpha-1(XII) chain isoform X1 Collagen alpha-1(XIX) chain isoform X1 Collagen alpha-1(XVII) chain isoform X1 Collagen alpha-1(XX) chain isoform X1 Collagen alpha-1(XXVII) chain isoform X1 Collagen alpha-1(XXVIII) chain Collagen alpha-1(XXVIII) chain Collagen alpha-2(I) chain precursor Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain precursor Collagen alpha-2(V) chain Collagen alpha-2(XI) chain isoform X2 Collagen alpha-3(IX) chain precursor Collagen alpha-3(V) chain isoform X1 Collagen alpha-3(VI) chain isoform X1 Collagen alpha-6(IV) chain isoform X1 Collagen beta(1-O)galactosyltransferase 2 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Prolyl 4-hydroxylase subunit alpha-1 Protein disulfide-isomerase procollagen galactosyltransferase procollagen-lysine 5-dioxygenase procollagen-lysine 5-dioxygenase procollagen-proline 3-dioxygenase procollagen-proline 4-dioxygenase procollagen-proline 4-dioxygenase	A0A6I8Q7J4 A0A6I8RHS2 A0A6I8RI28 A0A6I8S2R5 A0A6I8S8F1 A0A6I8SFH9 A0A6I8SGR0 A0A6I8SHU8 A0A6I8SPS1 A0A6I8SQ16 A0A6I8SQF8 A0A6I8SQU0 A0A6I8T0Y5 A0A803J251 A0A803J8Y6 A0A803JG94 A0A803JI90 A0A803JRW2 A0A803JXF0 A0A803K045 A0A803KF91 A0JM00 A0JP88 B1H3F6 B5DES3 F6QGI3 F6TF09 F6TWH3 F6ZQT7 F7AU67 Q0V9R5 Q28BS2 Q28EC8 Q640B2 Q6P4Z2	LOC100036633 LOC100145619 LOC100490088 LOC100492280 LOC100497990 LOC496414 adamts14 adamts3 col11a2 col11a2p1 col12a1 col17a1 col19a1 col1a1 col1a2 col20a1 col27a1 col28a1 col2a1 col3a1 col4a1 col4a2 col4a6 col5a1 col5a2 col6a3 col7a1 col9a1 col9a2 col9a3 colgalt1 colgalt2 dsi erba2l git oi4 otol1 p3h2 p4ha1 p4ha2 p4ha3 p4hb pdi pdia1 plod1 plod2 plod3 po4db po4hb prohb
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	Q5M8L5 Q5XGB0	akr1b1 akr1b7 sord	G58161NS
FGFR1c ligand binding and activation	Anosmin 1 Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family, member 1 Multifunctional fusion protein Transforming growth factor beta receptor III	A0A6I8PM12 A0A803J293 A0A803K518 A0A803KIA6 A9JRI8 B7U3X7 B7U3X8 F6XSB5 F6ZB49 F7DRT5 Q28DZ3 Q28J96 Q5M7S8	FGF-8 GIPC GIPC1 HBGF-1 HBGF-2 HBGF-4 Kermit X1FGFR XEFGF XFGFR-1 XGIPC Xfgf-4 Xfgf-8 Xfgf4 Xfgf8 aFGF admlx aigf anos1 bfgf bfgfr cd331 cek ecgf ecgf-beta ecgfa ecgfb efgf fgf-1 fgf-2 fgf-4 fgf-6 fgf-8b fgf-alpha fgf1 fgf2 fgf23 fgf23.1 fgf23.2 fgf4 fgf4-a fgf4-b fgf5 fgf6 fgf8 fgf8a fgf8b fgf9 fgfa fgfb fgfbr fgfe fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 gipc1 gipc3 glio703 glut1cbp hbgf-6 hbgf-8 hbgf1 hbgfr hbgh-2 hha hst hst-1 hst2 hstf1 iip-1 k-fgf kal kal1 kal2 kalig-1 kfgf kms n-sam ogd rgs19ip1 semcap synectiin tgfbr3 xfgf2 xfgfr1

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