GlyCosmos Portal

Xenopus tropicalis (tropical clawed frog)

Summary

Taxonomy ID: 8364
PubChem Taxonomy: 8364

Genes (320) Glycans (10) Glycoproteins (267) Lectins (10) Pathways (145)

Displaying entries **26 - 50** of **145** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	GlyTouCan ID
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A6I8PM12 A0A6I8SJT2 A0A803J293 A0A803K518 A0A803KIA6 B7U3X7 B7U3X8 B7UC02 B7ZSQ9 F6XSB5 F6Z8A1 F6ZB49 Q28DZ3 Q28J96 Q66IF7	FGF-8 HBGF-1 HBGF-2 HBGF-4 INT-2 X1FGFR XEFGF XFGFR-1 Xfgf-4 Xfgf-8 Xfgf4 Xfgf8 aFGF aigf bfgf bfgfr cd331 cek ecgf ecgf-beta ecgfa ecgfb efgf fgf-1 fgf-10 fgf-2 fgf-3 fgf-4 fgf-6 fgf-8b fgf-alpha fgf1 fgf10 fgf2 fgf22 fgf23.1 fgf23.2 fgf3 fgf4 fgf4-a fgf4-b fgf5 fgf6 fgf8 fgf8a fgf8b fgf9 fgfa fgfb fgfbr fgfe fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 glio703 hbgf-3 hbgf-6 hbgf-8 hbgf1 hbgfr hbgh-2 hst hst-1 hst2 hstf1 int2 k-fgf kal2 kfgf kl n-sam ogd plcg1 xfgf2 xfgf3 xfgfr1
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A6I8PM12 A0A6I8SJT2 A0A803K518 Q28J96	X1FGFR XFGFR-1 bfgfr cd331 cek fgf23.1 fgf23.2 fgfbr fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 hbgfr kal2 kl n-sam ogd xfgfr1
FGFR1c ligand binding and activation	Anosmin 1 Fibroblast growth factor 23 Fibroblast growth factor 23 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GIPC PDZ domain containing family, member 1 Multifunctional fusion protein Transforming growth factor beta receptor III	A0A6I8PM12 A0A803J293 A0A803K518 A0A803KIA6 A9JRI8 B7U3X7 B7U3X8 F6XSB5 F6ZB49 F7DRT5 Q28DZ3 Q28J96 Q5M7S8	FGF-8 GIPC GIPC1 HBGF-1 HBGF-2 HBGF-4 Kermit X1FGFR XEFGF XFGFR-1 XGIPC Xfgf-4 Xfgf-8 Xfgf4 Xfgf8 aFGF admlx aigf anos1 bfgf bfgfr cd331 cek ecgf ecgf-beta ecgfa ecgfb efgf fgf-1 fgf-2 fgf-4 fgf-6 fgf-8b fgf-alpha fgf1 fgf2 fgf23.1 fgf23.2 fgf4 fgf4-a fgf4-b fgf5 fgf6 fgf8 fgf8a fgf8b fgf9 fgfa fgfb fgfbr fgfe fgfr-1 fgfr1 fgfr1-a fgfr1-b flg flt-2 flt2 gipc1 gipc3 glio703 glut1cbp hbgf-6 hbgf-8 hbgf1 hbgfr hbgh-2 hha hst hst-1 hst2 hstf1 iip-1 k-fgf kal kal1 kal2 kalig-1 kfgf kms n-sam ogd rgs19ip1 semcap synectiin tgfbr3 xfgf2 xfgfr1
NOTCH3 Activation and Transmission of Signal to the Nucleus	E3 ubiquitin-protein ligase Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 LOC100127663 protein Neurogenic locus notch homolog protein 1 Nicastrin Novel protein Presenilin Presenilin Receptor protein-tyrosine kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A6I8PML7 A0A803K579 A0A803KJM5 A2RUV0 A8KBG4 F6UFM4 F6VJY6 F7C949 Q28FM7 Q28GF7 Q6AZL4 Q6GL58	LOC100127663 LOC100216108 LOC548926 MGC89679 RPS27A X-PS-alpha X-PS-beta X-ps-a X-ps-b ad3 ad3l ad4 aip2 aph-1a aph1a cep52 cgi-78 egf egfr fad hmg20 hubcep52 mds033 mstp064 ncstn notch1 pen-2 pen2 ps-a ps-alpha ps-b ps-beta ps1 ps2 psen1 psen2 psenen rgd1312037 rpl40 rps27a s182 stm2 uba52 ubc ubi-p63e wwp2 wwp2-like xegf
Noncanonical activation of NOTCH3	Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 1 Nicastrin Nuclease-sensitive element-binding protein 1 Presenilin Presenilin	A0A6I8PML7 A0A803K579 A0A803KJM5 A2RUV0 F7C949 Q28GF7 Q28IU4	X-PS-alpha X-PS-beta X-ps-a X-ps-b ad3 ad3l ad4 aph-1a aph1a bp-8 cgi-78 csda2 csdb dbpb fad frgy1 mdr-nf1 mds033 mstp064 ncstn notch1 nsep-1 nsep1 pen-2 pen2 ps-a ps-alpha ps-b ps-beta ps1 ps2 psen1 psen2 psenen rgd1312037 s182 stm2 yb-1 yb1 ybx1
Acyl chain remodelling of PE	Abhydrolase domain containing 4 Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophospholipid acyltransferase 1 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase LPCAT4 Phospholipase A and acyltransferase 1 Phospholipase A and acyltransferase 3 Phospholipase A and acyltransferase 3 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor phospholipase A2 phospholipase A2	A0A6I8PMU8 A0A6I8Q603 A0A6I8RYC6 A0A803K0T6 A0A803K1C6 A0A803KFH5 A4IIH1 B1H311 B1WAZ6 F6PVH0 F6TFZ5 F6VH26 F6VWC8 F7AE83 Q28C60 Q28D58 Q28GM9	LOC100145529 LOC116407767 abhd4 abhd5 agpat7 aytl3 cpla2 lpcat4 mboat1 mboat2 oact2 pla2 pla2a pla2g12a pla2g1b pla2g1bl pla2g2d pla2g3 pla2g4 pla2g4a pla2g4f pla2g6 pla2r1 plaat1 plaat3 plaat4 ppla2
Acyl chain remodelling of PS	Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophospholipid acyltransferase 1 Lysophospholipid acyltransferase LPCAT4 Oxysterol-binding protein Phospholipase A and acyltransferase 3 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor	A0A6I8PMU8 A0A6I8QPC8 A0A803K0T6 A0A803K1C6 A0A803KFH5 B1H311 B1WAZ6 F6PVH0 F6TFZ5 F6VWC8 Q28C60 Q28GM9	LOC100145529 LOC116407767 agpat7 aytl3 cpla2 lpcat4 mboat1 osbpl10 pla2 pla2a pla2g12a pla2g1b pla2g1bl pla2g2d pla2g4 pla2g4a pla2g4f pla2r1 plaat4 ppla2
Acyl chain remodelling of PC	Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophosphatidylcholine acyltransferase 1 Lysophospholipid acyltransferase 2 Lysophospholipid acyltransferase LPCAT4 Phospholipase A and acyltransferase 3 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor lysoplasmalogenase lysoplasmalogenase phospholipase A2 phospholipase A2	A0A6I8PMU8 A0A803K0T6 A0A803K1C6 A0A803KFH5 A4IIH1 A9UMH3 B0BMQ4 B1H311 B1WAZ6 F6PVH0 F6S3K0 F6TFZ5 F6VH26 F7AE83 Q28C60 Q28GM9	LOC100135356 LOC100145092 LOC100145529 LOC116407767 agpat7 aytl3 cpla2 lpcat1 lpcat4 mboat1 mboat2 oact2 pla2 pla2a pla2g12a pla2g1b pla2g1bl pla2g2d pla2g3 pla2g4 pla2g4a pla2g4f pla2g6 pla2r1 plaat4 ppla2 tmem86a tmem86b
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Frizzled class receptor 3 Frizzled class receptor 5 Frizzled-2 Frizzled-4 Guanine nucleotide binding protein (G protein), beta polypeptide 4 Guanine nucleotide binding protein, beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Mitogen-activated protein kinase kinase kinase 7 Mitogen-activated protein kinase Phosphodiesterase Phosphodiesterase Protein Wnt-11 Protein Wnt calcium/calmodulin-dependent protein kinase	A0A6I8PNV7 A0A6I8QRN7 A0A6I8QTD1 A0A6I8R459 A0A6I8RCH1 A0A6I8SDL6 A0A6I8SFN9 A0A6I8SIM1 A0A6I8T213 A0A803K619 A0A803KBZ4 A0A803KFL6 A4IGZ2 A4IIB5 A4QNP4 B0JZD9 B2GUT4 B3DLW1 F6VSL4 F7AZL7 F7EBE7 Q05B33 Q0VFL5 Q28G20 Q28H40 Q5XGD8 Q66KA3 Q6DF33	Fz-2 Fz-3 Go LOC100038286 LOC100124978 LOC733883 MAPKKK MGC145965 XGB1 XGalpha01 XGbeta1 Xfz2 Xfz3 Xnlk camk2 camk2a camkII camka frizzled-2 frizzled-3 frizzled2 frizzled3 frz-3 frz3 fz2 fz3 fzd2 fzd3 fzd4 fzd5 g-alpha-o g0a g0alpha ga0 gao gnao gnao1 gnb1 gnb2 gnb3 gnb4 gnb5 gng10 gng12 gng2 gng3 gng4 gng7 gng7-a gng7-b gngt1 gngt2.1 hfz3 map3k7 nlk nlk1 pde6a pde6b pi-plc plc-154 plc-i plc154 plcb1 plcb2 plcb3 tak1 wnt11 wnt11r wnt5a xTAK1
Alternative complement activation	A.superbus venom factor 1 Cathepsin G Complement C3 Complement factor B Serine protease ami	A0A6I8PQY9 A0A6I8Q3I4 A0A6I8S693 A9UMJ1 Q6P326	LOC100135369 LOC100170611 LOC100491968 ami cfb ctsg
Calcitonin-like ligand receptors	Calcitonin gene-related peptide 2 isoform X1 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Islet amyloid polypeptide Receptor activity-modifying protein 1	A0A6I8PR90 A0A803JC56 A0A803K560 Q0IIU7 Q0P4Y4	MGC147096 calca calcr calcrl iapp ramp1
Hedgehog 'off' state	G-protein coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Intraflagellar transport 140 Intraflagellar transport 172 Intraflagellar transport 88 Intraflagellar transport protein 122 homolog Intraflagellar transport protein 52 homolog isoform X1 Intraflagellar transport protein 57 homolog Meckel syndrome type 1 protein isoform X1 Patched 1 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Protein fantom Protein fuzzy homolog Protein inturned Protein kinase, cAMP dependent regulatory, type I beta Protein smoothened Suppressor of fused homolog Tetratricopeptide repeat domain 21B Tubby-related protein 3 WD repeat domain 19 adenylate cyclase adenylate cyclase adenylate cyclase adenylate cyclase adenylate cyclase adenylate cyclase adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit	A0A6I8PRC7 A0A6I8PXX7 A0A6I8PZU0 A0A6I8Q2A9 A0A6I8Q3A2 A0A6I8QBQ5 A0A6I8QGB6 A0A6I8QGP8 A0A6I8QPV8 A0A6I8RCT3 A0A6I8RRT2 A0A6I8SFS5 A0A6I8SXB5 A0A803JHS7 A0A803JRJ1 A0A803K6A2 A2VCZ2 A8WGF4 A8WH07 B1H1K3 B3DLW7 B3DM66 F6U5F9 F6ZYD6 F7DZP4 F7EI83 Q0IHN4 Q0P4Y3 Q28HX4 Q28I36 Q2HZX7 Q5BL84	Adcy3 LOC100127741 Xsufu ac7 adcy1 adcy4 adcy5 adcy6 adcy7 adcy8 c305c8.4 c380f5.1 cgi-53 cnc1 dnajc27 dnajc27-a dnajc27-b fuz fuzzy fy gli1 gli2 gli3 gpr161 gs114 ift122 ift140 ift172 ift52 ift57 ift88 intu mes mks mks1 ngd5 pik3cg pkr1 ppnad1 prkaca prkar1 prkar1a prkar1a.2 prkar1b prkar2a prkar2b pro1280 ptch1 pwdmp rap1 rpgrip1l smo sufu sufuh sufuxl tse1 ttc21b tubl3 tulp3 wdr19 wdtc2
Synthesis of PC	Abhydrolase domain containing 3 Carboxylic ester hydrolase Choline transporter-like protein 5 Choline transporter-like protein Choline transporter-like protein Choline transporter-like protein Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 LOC100145047 protein LOC100158578 protein Lysophosphatidylcholine acyltransferase 1 Phosphatase, orphan 1 Phosphatidylethanolamine N-methyltransferase Sodium-dependent lysophosphatidylcholine symporter 1 choline-phosphate cytidylyltransferase ethanolamine kinase ethanolamine kinase phosphatidate phosphatase phosphatidate phosphatase	A0A6I8PRS6 A0A6I8PZR8 A0A6I8QKB0 A0A6I8R4V8 A0A6I8RU49 A0A6I8STK1 B0BMI7 B0JZD0 B0JZE0 B2GUF4 F6S3K0 F6WD25 F6WFG7 F7A321 F7DAV8 Q0IHM1 Q28H54 Q4VA73 Q5I086	LOC100145047 LOC100145186 LOC100158578 PEMT abhd3 bchel cept1 chka chkb chpt1 ctl5 labh3 lpcat1 lpin1 lpin2 mfsd2 mfsd2a mgc108095 nls1 pap1 pcyt1a pemt phospho1 slc44a1 slc44a2 slc44a4 slc44a5 stard10 stard7
Synthesis of PE	Choline/ethanolaminephosphotransferase 1 Ethanolamine-phosphate phospho-lyase Phosphatase, orphan 1 ethanolamine kinase ethanolamine kinase ethanolamine kinase ethanolamine-phosphate cytidylyltransferase phosphatidate phosphatase phosphatidate phosphatase	A0A6I8PRS6 A0A6I8QKB0 A0A803KDW6 A4IHZ6 B0JZE0 F6WFG7 F7CXF7 Q28H54 Q5I086	LOC100124921 LOC100145186 agxt2l1 cept1 chka chkb etnk1 etnppl lpin1 lpin2 pap1 pcyt2 phospho1
RHOQ GTPase cycle	ADP ribosylation factor-like GTPase 13A Amino acid transporter Arhgap1 protein CDC42 effector protein (Rho GTPase binding) 3 CDC42 effector protein (Rho GTPase binding) 4 CDC42 effector protein 1 Caveolin Cdc42 effector protein 2 Cell division control protein 42 homolog Copine VIII DEP domain-containing protein 1B E3 ubiquitin-protein ligase Erythrocyte band 7 integral membrane protein isoform X1 Gap junction protein Glucose-fructose oxidoreductase domain-containing protein 1 IQ motif-containing GTPase-activating protein 1 IQ motif-containing GTPase-activating protein 3 Junction plakoglobin MAGUK p55 subfamily member 7 Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein RAB7A, member RAS oncogene family Ragulator complex protein LAMTOR1 Ras homolog family member Q Rho GTPase activating protein 32 Rho GTPase activating protein 5 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 7 Synaptosomal-associated protein Vang-like protein 1 Vesicle-associated membrane protein 3 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A6I8PS67 A0A6I8QAF6 A0A6I8QN72 A0A6I8RQF4 A0A6I8S4C5 A0A6I8SQB3 A0A6I8SVR6 A0A7D9N0I0 A0A803JEV9 A0A803JMX2 A0A803JZT1 A0A803K5Z0 A2RUV4 A8KBF6 A9UL74 B2GUH1 B5DFQ4 F6QPU0 F6RLQ1 F6T2D3 F6VJY6 F6WBH7 F6ZFY1 F7C3I3 F7C9K9 F7CV14 Q0P4U1 Q28BZ0 Q28CX6 Q28E65 Q28IP7 Q28IQ8 Q66IH1 Q66JI1 Q6P259 Q6P2W7 Q6P4M5	Cav-1 LOC100135161 LOC100158588 LOC116408733 LOC549726 LOC733993 XCEP2 Xcdc42 aaat aip2 arhgap1 arhgap1-a arhgap1-b arhgap21 arhgap26 arhgap32 arhgap33 arhgap35 arhgap5 arhgef7 arl13a arvd12 asct2 atbo borg2 borg4 brcc3 bscl3 cav cav1 cav1-a cav1-b caveolin-1 cdc42 cdc42ep1 cdc42ep2 cdc42ep3 cdc42ep4 cdc42gap cdc42hs ceb cep3 cep4 cgl3 connexin43 cpne8 ctnng cx43 depdc1b dfnb38 dlc1 dp3 dpiii g25k gfod1 gja1 gjal iqgap1 iqgap3 jup jup-a jup-b kaia1777 lamtor1 m7v1 m7vs1 mpp7 mrx60 mstp085 noma-gap oddd ophn1 opn1 p50rhogap pak-4 pak1 pak4 pdgb pkgb plakoglobin prex1 pro2706 r16 rab7 rab7a rdrc rhogap rhogap1 rhogap68f rhoq slc1a5 snap23 snx26 stom tcgap ub1 vamp-3 vamp3 vip21 wwp2 wwp2-like xtp1
WNT ligand biogenesis and trafficking	Protein Wnt-11 Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein wntless homolog Sorting nexin-3 Transmembrane emp24 domain-containing protein 5 Vacuolar protein sorting-associated protein 26A Vacuolar protein sorting-associated protein 29 Vacuolar protein sorting-associated protein 35	A0A6I8PTQ1 A0A6I8R7P2 A0A6I8RA94 A0A803J6C2 A0A803JA58 A0A803JRJ6 A0A803JYV5 A0A803K040 A0A803K3R1 A0A803K592 A0A803KBZ4 A0JMB0 A4ZGN9 A4ZGP0 A4ZGP2 B0JYX1 B2GUT4 B3DL72 F7A8Q1 F7AZV5 F7D1A1 Q28HT6 Q28HX3 Q6DEU3 Q6DII0	Grd19 Wnt16 Wnt3 Wnt9b Xp24g2 Xp24gamma2 Xwnt-10b Xwnt-3 Xwnt-7B Xwnt-8 Xwnt10b Xwnt3 Xwnt7B Xwnt8 cgi-100 evi gpr177 int4 mem3 mrp sdp3 snx12 snx3 snx3a tmed5 vps26a vps29 vps35 wls wnt-12 wnt-3 wnt-5b wnt-7b wnt-8 wnt-9b wnt1 wnt10a wnt10b wnt11 wnt11r wnt16 wnt2 wnt2b wnt3 wnt3a wnt3l wnt5a wnt5b wnt6 wnt7a wnt7b wnt8 wnt8a wnt8b wnt8d wnt9a wnt9b wntless xwnt5b
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 Alpha-2-macroglobulin-like 1 pseudogene Alpha-2-macroglobulin Alpha-2-macroglobulin Basigin Brevican core protein Calpain 14 Calpain 7 Calpain 8 gene 5 Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-13 Calpain-2 catalytic subunit Calpain-3 Calpain-5 Calpain-6 Calpain-9 Cathepsin G Cathepsin S Collagenase 3-like Collagenase 3 Collagenase 3 MGC89057 protein Matrix metallopeptidase 11 Matrix metallopeptidase 14 (Membrane-inserted) Matrix metallopeptidase 19 Matrix metallopeptidase 1 Matrix metallopeptidase 20 Matrix metallopeptidase 3 precursor Matrix metalloproteinase-18 Matrix metalloproteinase-9 Opticin Signal peptide, CUB and EGF-like domain-containing protein 1 isoform X1 interstitial collagenase	A0A6I8PU05 A0A6I8PVU9 A0A6I8PY14 A0A6I8QBM5 A0A6I8QT93 A0A6I8QUP1 A0A6I8R102 A0A6I8RC49 A0A6I8RND2 A0A6I8RP28 A0A6I8S643 A0A6I8SPW3 A0A803JT32 A0A803K4H8 A0A803KC39 A9UMJ1 B2GUG2 F6SRT1 F6TCS3 F6TCT8 F6TVV1 F6Y400 F6YLX6 F7B862 F7DI46 Q28FK8 Q28HP1 Q28IS0 Q28J86 Q4QQQ9 Q5BL52 Q5FVW8 Q66IH0 Q66JI2 Q6DF35 Q6DIP0	CAPN1 CD147 LOC100135369 LOC100158582 LOC100489060 LOC100489108 LOC100491214 LOC100491547 LOC100495980 LOC101731595 LOC101731804 LOC116408897 MGC89057 MMP-14 MMP-18 MMP7 MMP8 MT-MMP-1 Xmmp2 a2m adamts4 adamts5 bcan bsg calpb canp canpl1 capn1 capn11 capn13 capn14 capn3 capn5 capn6 capn7 capn8.5 capn9 capns1 capns2 chds6 clg clg3 clg4 clg4a clgn col3 col4 ctsg ctss ctss-a ctss-b ctss.1 htra3 mandp1 matrilysin mgc108008 mmp-3 mmp-7 mmp-ii mmp-x1 mmp1 mmp10 mmp11 mmp13 mmp13l mmp14 mmp18 mmp19 mmp2 mmp20 mmp3 mmp7 mmp8 mmp9.1 mmp9.2 mona mt1-mmp mtmmp1 mucanp mucl ncl-3 optc ovos2 pump-1 pzp scube1 sl-1 stmy stmy1 str1 tbe-1 xcol4
Phosphate bond hydrolysis by NTPDase proteins	Ectonucleoside triphosphate diphosphohydrolase 1 Ectonucleoside triphosphate diphosphohydrolase 2 Ectonucleoside triphosphate diphosphohydrolase 3 Ectonucleoside triphosphate diphosphohydrolase 4 Ectonucleoside triphosphate diphosphohydrolase 6 (putative) Ectonucleoside triphosphate diphosphohydrolase 7 Ectonucleoside triphosphate diphosphohydrolase 8	A0A6I8PVI8 A0A6I8QE61 A4IIK2 K9J7Q8 Q28CF8 Q6DFS1 Q6NVI9	LALP70 LOC100125010 NTPDase1 NTPDase2 NTPDase3 NTPDase4 entpd1 entpd2 entpd3 entpd4 entpd6 entpd7 entpd8
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-like hormone Parathyroid hormone/parathyroid hormone-related peptide receptor	A0A6I8PVS6 A0A6I8QCI3 A0A6I8SNF4 A0A6I8SZJ5 A0A6R5A8C8 A0A803KFJ5 F6WB14	LOC100485454 LOC100490939 crhbp crhr1.2 pth1r pth2r pthlh
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 1 precursor A disintegrin and metalloproteinase with thrombospondin motifs 12 isoform X1 A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1 A disintegrin and metalloproteinase with thrombospondin motifs 15 A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 19 isoform X1 A disintegrin and metalloproteinase with thrombospondin motifs 3 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 6 A disintegrin and metalloproteinase with thrombospondin motifs 7 isoform X1 ADAMTS-like 3 ADAMTS-like 4 ADAMTS-like protein 5 isoform X1 Beta 3-glucosyltransferase Complement factor properdin precursor GDP-fucose protein O-fucosyltransferase 2 Somatomedin B and thrombospondin type 1 domain containing Spondin 2, extracellular matrix protein Spondin-1 Thrombospondin type 1 domain containing 4 Thrombospondin type 1 domain-containing 1 Thrombospondin type 1 domain-containing 7B Thrombospondin-1 Thrombospondin-2	A0A6I8PW79 A0A6I8QIW1 A0A6I8R102 A0A6I8R3P0 A0A6I8R5U5 A0A6I8R7I7 A0A6I8RQ44 A0A6I8RWI7 A0A6I8SGR0 A0A6I8SHU8 A0A6I8SQB2 A0A6I8T030 A0A6I8T1W7 A0A7D9NLY6 A0A803K207 A0A803KK82 A1L1E3 B2GUP2 F6RRX5 F7B862 F7B874 F7BL46 F7CZ02 F7DBN5 Q00P39 Q5XGJ3	F-spondin LOC100036727 LOC100487633 XB995277 adamts1 adamts12 adamts14 adamts15 adamts16 adamts18 adamts19 adamts3 adamts4 adamts5 adamts6 adamts7 adamtsl3 adamtsl4 b3galtl b3glct bfd c3-c5 cfp fut13 meth1 pfc pfd pofut2 properdin sbspon spon1 spon2 thbs1 thbs2 thsd1 thsd4 thsd7b xadamts1
Cell surface interactions at the vascular wall	Carcinoembryonic antigen-related cell adhesion molecule 1-like Carcinoembryonic antigen-related cell adhesion molecule 16 isoform X1 Carcinoembryonic antigen-related cell adhesion molecule 16 Carcinoembryonic antigen-related cell adhesion molecule 1 Carcinoembryonic antigen-related cell adhesion molecule 8 E-selectin Epithelial cell adhesion molecule Fibronectin Gas6 protein Glypican-1 Golgi apparatus protein 1 Hemicentin 1 Integrin alpha-4 Integrin alpha-5 Integrin beta Junctional adhesion molecule 2 Junctional adhesion molecule 3 Junctional adhesion molecule A Syndecan Syndecan Tyrosine-protein kinase Tyrosine-protein kinase Vitamin K-dependent protein S receptor protein-tyrosine kinase	A0A6I8PWW5 A0A6I8RSV6 A0A6I8S3G9 A0A6I8S833 A0A6I8SB33 A0A6I8ST12 A0A803JC53 A0A803JF35 A0A803JTZ0 A0A803JV29 A0A803K8M1 B2GUS2 F6Q166 F6RH77 F6ZQ00 L7N3S5 Q0V9W0 Q0VFK4 Q28E66 Q28HM3 Q28IV0 Q501R6 Q5U4Z2 Q66JI5	FN LOC101732140 LOC116412429 LOC733989 MGC79514 axllg axsf cd29 cd321 cd322 cd326 ceacam19lm ceacam8 ceacam8l cig co17-1a egp egp40 ep-cam epcam epcam-a epcam-b f11r fibronectin finc fn1 fnrb fyn ga733-2 gas6 glg1 gpc1 gpiia hegp-2 hmcn1 hspg hspg1 itga4 itga5 itgb1 itgb1-a itgb1-b jam jam-b jam1 jam2 jam3 jama jamb jcam jtk8 kat ksa lets lyn m4s1 mdf2 mertk mic18 mk-1 msf msk12 pam-1 pro245 pros1 sdc1 sdc2 sdc2-a sdc2-b selp synd2 syndecan-2 tacstd1 trop1 ve-jam vejam vla-beta vlab
Stimuli-sensing channels	Acid sensing ion channel subunit family member 4 Acid-sensing ion channel 1 Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma isoform X1 Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Bestrophin homolog Bestrophin homolog Bestrophin homolog Bestrophin homolog Calcium-activated chloride channel regulator 1 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Erythrocyte band 7 integral membrane protein isoform X1 Osteopetrosis-associated transmembrane protein 1 Protein tweety homolog 1 Protein tweety homolog 2 Protein tweety homolog Sodium/hydrogen exchanger 9B2 Stomatin (EPB72)-like 3 Two pore calcium channel protein 2	A0A6I8PWZ4 A0A6I8PYE3 A0A6I8Q0X6 A0A6I8Q706 A0A6I8QME6 A0A6I8R312 A0A6I8RU90 A0A6I8SNU5 A0A803JCJ8 A0A803K5Z0 A0A803KJN0 A4IHB9 B1H141 B3DLV2 C4TNR5 C4TNR6 F6UIB2 F6V0E2 F6VMZ3 F6W3N3 F6ZLF5 F6ZZ82 F7AE39 Q0IHW1 Q0V998 Q0V9V9 Q28C02 Q28C29 Q6P1U2 Q6P362 Q6P851	Best-1 Best-3 ClC-5 ENaCalpha LOC100145074 LOC100170550 LOC101732476 MGC145644 MGC147551 MGC75647 alpha-ENaC ano1 ano10 ano2 ano4 ano5 ano6 ano8 asic1 asic4 besc1 besc2 best-1 best-3 best1 best2 best2-a best2-b best3 best4 beta-ENaC clca2 clcn2 clcn4 clcn5 clcn6 clcn7 dog1 enaca enacb enacbeta nha2 nhedc2 oraov2 ostm1 scnea scneb scnn1 scnn1a scnn1b scnn1b-a scnn1b-b scnn1d scnn1g slc9b2 stom stoml3 taos2 tmem16a tpcn2 ttyh1 ttyh2 ttyh3 vmd2l1 vmd2l2 xTMEM16A
Hedgehog 'on' state	Cell division cycle 73 Cullin-3 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Ellis van Creveld syndrome 2 Ellis-van Creveld syndrome protein G-protein coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Novel protein Numb homolog (Drosophila) Patched 1 Protein smoothened Speckle-type POZ protein-like Speckle-type POZ protein Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A6I8PYJ0 A0A6I8QGB6 A0A6I8RCT3 A0A6I8RRT2 A0A6I8S8I3 A0A6I8SVL3 A0A803JPT9 A0A803JRJ1 A0JM32 A4IH32 A4IHP4 B3DLW7 B3DM66 F6V904 F7DZP4 Q07FY6 Q28FM7 Q5BKG2 Q6AZL4 Q6GL58 Q6P8B3	LOC100216108 LOC548926 MGC89679 RPS27A Xsufu aif4 aip4 cdc73 cep52 cul3 dwf-1 evc evc2 evcl gli1 gli2 gli3 gpr161 hmg20 hrpt2 hubcep52 itch itchy napp1 numb pro1280 ptch1 rbx1 rpl40 rps27a s171 smo smurf1 smurf2 spop spopl sufu sufuh sufuxl uba52 ubc ubi-p63e
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase Alpha-1,4 glucan phosphorylase Glycogen debranching enzyme Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit glycogenin glucosyltransferase glycogenin glucosyltransferase glycogenin glucosyltransferase phosphorylase kinase	A0A6I8PZI8 A0A6I8Q841 A0A6I8SDS9 A0A6I8T1Z9 F6UTW9 F6VIR5 F6WBB6 Q5M7A1 Q6P328	LOC100491051 LOC496877 agl gyg gyg1 gyg2 phka1 phka1p1 phka2 phkb phkg2 pygb pygl	G58161NS
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A6I8Q186 A0A6I8SCF3 A0A803JX40 B0BLW6 F6Z0J4 Q0IHS8	LOC100144924 LOC100498409 PI3-kinase PI3K-alpha irs1 p110-beta pi3-k pi3k pi3k92e pi3kbeta pik3c1 pik3ca pik3cb pik3r1 pik3r2

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