GlyCosmos Portal

Canis familiaris (dog)

Summary

Taxonomy ID: 9615
PubChem Taxonomy: 9615

Genes (1435) Glycans (57) Glycoproteins (513) Lectins (17) Pathways (270)

Displaying entries **226 - 250** of **270** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensin-converting enzyme Angiotensinogen Carboxylesterase 5A Carboxypeptidase B1 Carboxypeptidase B2 Cathepsin D Cathepsin G Chymase Neprilysin Renin receptor Renin cathepsin X	A0A8I3NK04 A0A8I3NT46 A0A8I3P176 A0A8I3PJS4 A0A8I3PTV1 A0A8I3QCM1 A0A8I3RP60 A0A8I3RR88 A0A8I3RUJ7 A0A8I3S392 F5C3N2 P21842 Q4LAL9 Q6DYE7	ACE ACE2 AGT ATP6AP2 CES5A CMA1 CPA3 CPB2 CTSD CTSG CTSZ ENPEP MME REN
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A8I3N3U3 A0A8I3NGY1 A0A8I3NUU1 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3QSS9 A0A8I3S3D9 Q867B7	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1
Galactose catabolism	Galactokinase 1 Galactokinase Galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase	A0A8I3P3X5 A0A8I3PNL4 A0A8I3PT77 Q9GKK4	GALE GALK1 GALT H3-3B	G93924TT
Lysosomal oligosaccharide catabolism	Alpha-mannosidase alpha-mannosidase beta-mannosidase	A0A8I3P3N3 A0A8I3PHW0 A0A8I3PSC3	MAN2B1 MAN2C1 MANBA	G00027MO G25577BM G28233ME G70323CJ G90333CG
Sphingolipid de novo biosynthesis	3-dehydrosphinganine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 heme-binding domain-containing protein Delta 4-desaturase, sphingolipid 2 Fatty acid 2-hydroxylase Major facilitator superfamily domain containing 2B Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 ORM1-like protein ORM1-like protein ORM1-like protein SPNS lysolipid transporter 2, sphingosine-1-phosphate Serine palmitoyltransferase 1 Serine palmitoyltransferase long chain base subunit 2 Serine palmitoyltransferase long chain base subunit 3 Sphingolipid delta(4)-desaturase DES1 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Uncharacterized protein Uncharacterized protein	A0A8I3MDB1 A0A8I3MDX2 A0A8I3MH69 A0A8I3MTG4 A0A8I3MVV0 A0A8I3MZT5 A0A8I3N0C8 A0A8I3N1I8 A0A8I3N6A8 A0A8I3N8H8 A0A8I3NCL9 A0A8I3NE51 A0A8I3NF48 A0A8I3P1Y0 A0A8I3P1Z6 A0A8I3P4B7 A0A8I3PAM7 A0A8I3PG24 A0A8I3PM33 A0A8I3PMG7 A0A8I3PQ53 A0A8I3Q2P7 A0A8I3S0D0 A0A8I3S194 A0A8I3S6X3 A0A8I3S790 B3RFJ1 Q6UR05	ABCC1 ABCG2 Abcg2 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CYB5B DEGS1 DEGS2 FA2H KDSR MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPNS2 SPTLC1 SPTLC2 SPTLC3 SPTSSA
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin 4	A0A8I3MMP8 A0A8I3N5C8 A0A8I3NGY1 A0A8I3NIW4 Q867B7	HGF ITGB1 MET TNS3 TNS4
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ADRM1 26S proteasome ubiquitin receptor ATP binding cassette subfamily A member 4 ATP binding cassette subfamily A member 8 ATP binding cassette subfamily B member 1 ATP binding cassette subfamily B member 4 ATP binding cassette subfamily B member 5 ATP binding cassette subfamily B member 9 ATP binding cassette subfamily C member 10 ATP binding cassette subfamily C member 11 ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 ATP binding cassette subfamily C member 9 ATP binding cassette subfamily F member 1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Derlin Derlin Derlin E3 ubiquitin-protein ligase RNF Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein protein-synthesizing GTPase	A0A8I3MFR7 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MR89 A0A8I3MV19 A0A8I3N0P1 A0A8I3N153 A0A8I3N165 A0A8I3N1B7 A0A8I3N1I8 A0A8I3N222 A0A8I3N2I4 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N6K4 A0A8I3N6T3 A0A8I3N6X7 A0A8I3N7G8 A0A8I3N9B0 A0A8I3N9G3 A0A8I3NB03 A0A8I3NFB9 A0A8I3NH42 A0A8I3NKE8 A0A8I3NN65 A0A8I3NND5 A0A8I3NNJ9 A0A8I3NNW7 A0A8I3NP66 A0A8I3NPX1 A0A8I3NUC6 A0A8I3NV30 A0A8I3NVA4 A0A8I3NW81 A0A8I3NXK9 A0A8I3NXV6 A0A8I3NZK9 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PGC3 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PM01 A0A8I3PME6 A0A8I3PVZ3 A0A8I3PZT2 A0A8I3Q3Z7 A0A8I3Q7I5 A0A8I3QV78 A0A8I3QYD0 A0A8I3RRR7 A0A8I3RT39 A0A8I3RU74 A0A8I3RV68 A0A8I3RXV3 A0A8I3RZD9 A0A8I3S0X8 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3SCV5 B8K1W7 P63050 Q5U820 Q6UR05	ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 ADRM1 Abcc4 CFTR DERL1 DERL2 DERL3 EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 KCNJ11 LOC100686569 LOC100687259 MRP1 OS9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMB1 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RNF5 RPS27A SEL1L UBA52 UBB UBC UBCEP2 VCP
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Vav guanine nucleotide exchange factor 1 cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3N974 A0A8I3NA65 A0A8I3NBM3 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PBB4 A0A8I3PMT9 A0A8I3PRW9 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q4Y8 A0A8I3Q525 A0A8I3RVE7 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3N2 P48749 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB IL3 IL5 IL5RA JAK2 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ
Phase 4 - resting membrane potential	Inward rectifier potassium channel 2 Inward rectifier potassium channel Potassium channel domain-containing protein Potassium channel subfamily K member 9 Potassium channel subfamily K member Potassium inwardly rectifying channel subfamily J member 14 Potassium two pore domain channel subfamily K member 10 Potassium two pore domain channel subfamily K member 12 Potassium two pore domain channel subfamily K member 13 Potassium two pore domain channel subfamily K member 15 Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 17 Potassium two pore domain channel subfamily K member 18 Potassium two pore domain channel subfamily K member 4 Potassium two pore domain channel subfamily K member 5 Potassium two pore domain channel subfamily K member 6 Potassium two pore domain channel subfamily K member 7	A0A8I3MR75 A0A8I3MTD8 A0A8I3MV05 A0A8I3N317 A0A8I3NAZ8 A0A8I3NNF9 A0A8I3NSP8 A0A8I3NUT1 A0A8I3NUY1 A0A8I3P863 A0A8I3Q3Z0 A0A8I3Q644 A0A8I3RRG3 A0A8I3S0J2 A0A8I3S6X0 F6KIF6 Q9MYY9	IRK1 KCNJ12 KCNJ14 KCNJ2 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK18 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4
Synthesis of bile acids and bile salts	Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Retinoic acid receptor RXR	A0A8I3N2S7 A0A8I3NA48 A0A8I3NIH7 A0A8I3NPK5 A0A8I3NS93 A0A8I3P033 A0A8I3P4G5 A0A8I3PNT4 A0A8I3PRC4 A0A8I3PYI4 A0A8I3S236 A0A8I3S5H8 A0A8I3SAZ3	CYP7A1 CYP7B1 NCOA1 NCOA2 NR1H4 OSBP OSBPL1A OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RXRA
Tie2 Signaling	Angiopoietin 4 Angiopoietin-1 Angiopoietin-2 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 14 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N971 A0A8I3NC50 A0A8I3NID0 A0A8I3NM36 A0A8I3NUU1 A0A8I3NZA4 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1A9 A0A8I3Q1I3 A0A8I3S0B4 A0A8I3S3D9 A0A8I3S3N2 A0A8J8	ANGPT1 ANGPT2 ANGPT4 DOK2 GRB14 GRB2 GRB7 HRAS KRAS NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PTPN11 SHC1 SOS1 TEK
Na+/Cl- dependent neurotransmitter transporters	Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent glycine transporter 1 Solute carrier family 18 member A1 Solute carrier family 18 member A2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 6 member 13 Solute carrier family 6 member 6 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A8I3MBP6 A0A8I3MM56 A0A8I3MNK2 A0A8I3N6A1 A0A8I3N7M6 A0A8I3NCF6 A0A8I3NLL1 A0A8I3P2T9 A0A8I3PHP5 A0A8I3PME4 A0A8I3PQT8 A0A8I3PSN6 A0A8I3PV06 A0A8I3Q066 A0A8I3QQP1 A0A8I3QS48 A0A8I3RV00 A0A8I3S5V8 P27799	SLC18A1 SLC18A2 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 FLVCR heme transporter 1 Ferritin heavy chain Ferritin light chain Ferritin Ferritin Ferritin Ferroportin Heme oxygenase 1 Iron-responsive element-binding protein 2 Lipocalin 2 NEDD8 Plasma membrane ascorbate-dependent reductase CYBRD1 Proton-coupled folate transporter S-phase kinase-associated protein 1 Solute carrier family 11 member 2 Solute carrier family 22 member 17 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ferroxidase ferroxidase heme oxygenase (biliverdin-producing)	A0A8I3ME81 A0A8I3MH42 A0A8I3MHS3 A0A8I3MKF8 A0A8I3MMN5 A0A8I3N1L5 A0A8I3N2C0 A0A8I3N2D2 A0A8I3N4B0 A0A8I3N8Y0 A0A8I3NAI4 A0A8I3NFB9 A0A8I3NP41 A0A8I3NPT2 A0A8I3NT24 A0A8I3NZI4 A0A8I3PMF7 A0A8I3Q213 A0A8I3Q9B0 A0A8I3QDX8 A0A8I3QYD0 A0A8I3RZ10 A0A8I3S0Z7 B3RFJ1 E2RFJ3 P63050 Q53VB8 Q95MP7	ABCG2 ACO1 Abcg2 CAND1 CP CUL1 CYBRD1 FBXL5 FLVCR1 FTH FTH1 FTL HEPH HMOX1 HMOX2 IREB2 LCN2 LOC119865338 LOC119878918 LOC608550 NEDD8 RPS27A SKP1 SLC11A2 SLC22A17 SLC40A1 SLC46A1 UBA52 UBB UBC UBCEP2
Uptake of dietary cobalamins into enterocytes	ATP binding cassette subfamily D member 4 Chymotrypsinogen 2 Cobalamin binding intrinsic factor Lysosomal cobalamin transport escort protein LMBD1 Transcobalamin-like C-terminal domain-containing protein trypsin	A0A8I3N584 A0A8I3P9U6 A0A8I3PD99 A0A8I3S4Z0 P04813 Q5XWD5	CBLIF CTRB CTRB1 GIF LMBRD1 LOC119869278 PRSS2 TCN1
PI-3K cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3N971 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 GAB1 GRB2 PIK3CA PIK3R1 PTPN11
Glycosaminoglycan metabolism	UDP-glucuronate decarboxylase 1	A0A8I3NBE0	UXS1
Glycolysis	ADP dependent glucokinase ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase Beta-enolase Enolase 4 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucosamine-6-phosphate isomerase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Hexokinase-1 Hexokinase-2 Phosphoglucomutase 2 like 1 Phosphoglycerate kinase Phosphoglycerate kinase Phosphoglycerate mutase Phosphoglycerate mutase Phosphoglycerate mutase Phosphotransferase Pyruvate kinase PKLR Triosephosphate isomerase hexokinase hexokinase phosphopyruvate hydratase phosphopyruvate hydratase	A0A8I3MJP4 A0A8I3MK58 A0A8I3MKD5 A0A8I3MKW3 A0A8I3MLI6 A0A8I3MVF3 A0A8I3MYU3 A0A8I3N1E7 A0A8I3N4J1 A0A8I3N504 A0A8I3N9R0 A0A8I3NII5 A0A8I3NIY6 A0A8I3NMJ6 A0A8I3NTY8 A0A8I3P147 A0A8I3P1K1 A0A8I3P2U1 A0A8I3P7P5 A0A8I3P9Y9 A0A8I3PRM7 A0A8I3PU48 A0A8I3PVY7 A0A8I3PZE8 A0A8I3Q5N9 A0A8I3Q5Z0 A0A8I3RRW0 A0A8I3RWL6 A0A8I3S3G1 A0A8I3SC19 Q29536	ADPGK ALDOA ALDOB ALDOC BPGM ENO2 ENO3 ENO4 GAPDH GAPDHS GCK GNPDA1 GNPDA2 GPI HK1 HK2 HK3 HKDC1 LOC106558132 PFKL PFKM PFKP PGAM1 PGAM2 PGK1 PGK2 PGM2L1 PKLR TPI1	G58161NS
SHC-mediated cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GRB2 HRAS KRAS NRAS SHC1 SOS1
Translocation of ZAP-70 to Immunological synapse	Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein protein-tyrosine-phosphatase	A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MKK6 A0A8I3MV98 A0A8I3MZ69 A0A8I3NAC6 A0A8I3NTK0 A0A8I3P4A1 A0A8I3P564 A0A8I3P8U2 A0A8I3PAB8 A0A8I3PC26 A0A8I3S023 A0A8I3S2N1 A0A8I3S3J5 P27597 P33705	CD247 CD3D CD3E CD3G CD4 DLA-DQA1 DLA-DRA HLA-DQB2 LCK PTPN22 TRAV29DV5 ZAP70
COPII-mediated vesicle transport	Alpha 1 antitrypsin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Casein kinase I isoform delta Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein NSF attachment protein alpha NSF attachment protein beta Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 2 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22 homolog A, vesicle trafficking protein SEC22 homolog B, vesicle trafficking protein SEC22 homolog C, vesicle trafficking protein SEC23 interacting protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SEC31 homolog B, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Small COPII coat GTPase SAR1B Syntaxin 17 Syntaxin 5 TBC1 domain family member 20 Trafficking from ER to golgi regulator Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Trafficking protein particle complex subunit Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Vesicle-fusing ATPase Vesicular integral-membrane protein VIP36 YKT6 v-SNARE homolog cathepsin X small monomeric GTPase	A0A8I3MAV2 A0A8I3MJ74 A0A8I3MLH1 A0A8I3MLQ0 A0A8I3MT73 A0A8I3MT80 A0A8I3MUS5 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3MZY0 A0A8I3N2I9 A0A8I3N5A8 A0A8I3N5C1 A0A8I3N796 A0A8I3N7P4 A0A8I3N9C4 A0A8I3N9V0 A0A8I3NBA1 A0A8I3NCZ9 A0A8I3NFJ9 A0A8I3NKE3 A0A8I3NPG4 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NX57 A0A8I3NYM5 A0A8I3NZH7 A0A8I3NZS8 A0A8I3P0W8 A0A8I3P2X8 A0A8I3P4I1 A0A8I3PAS9 A0A8I3PEN5 A0A8I3PNK8 A0A8I3PQR9 A0A8I3PTJ0 A0A8I3PTW0 A0A8I3PU34 A0A8I3PV59 A0A8I3PVF9 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q4E7 A0A8I3Q5G1 A0A8I3Q7H2 A0A8I3QC45 A0A8I3QS42 A0A8I3RR85 A0A8I3RRF7 A0A8I3RSX1 A0A8I3RU45 A0A8I3RUA0 A0A8I3RVH6 A0A8I3RWZ7 A0A8I3RZB2 A0A8I3S3N8 A0A8I3S444 A0A8I3S449 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 E2QV03 P49256 P62822	ANKRD28 AREG BET1 CD59 CNIH1 CNIH2 CNIH3 CSNK1D CTSC CTSZ F5 GOLGA2 GORASP1 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 NAPA NAPB NAPG NSF PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A SCFD1 SEC13 SEC16A SEC16B SEC22A SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SEC31B SERPINA1 STX17 STX5 TBC1D20 TFG TGFA TMED10 TMED2 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 USO1 YKT6
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein Choline transporter-like protein Choline transporter-like protein Choline transporter-like protein Choline transporter-like protein Multidrug and toxin extrusion protein Multidrug and toxin extrusion protein Solute carrier family 10 member 6 Solute carrier family 5 member 7 Urea transporter 1 Urea transporter 2	A0A8I3MMY0 A0A8I3MSY0 A0A8I3MT90 A0A8I3N5A5 A0A8I3NGN2 A0A8I3NPI6 A0A8I3NVU1 A0A8I3P335 A0A8I3PJ18 A0A8I3PWN4 A0A8I3RY71	SLC10A6 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 SLC47A1 SLC47A2 SLC5A7
Relaxin receptors	Insulin-like 3 Relaxin 2 Relaxin family peptide receptor 1 Relaxin family peptide receptor 3 Relaxin receptor 2 Relaxin-3	A0A8I3NLX3 A0A8I3PPP9 A0A8I3RPW6 A0A8I3RZ39 Q5XM32 Q6X7V3	INSL3 LGR8 RLF RLN2 RLN3 RXFP1 RXFP2 RXFP3
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 B7-1 protein Brain-derived neurotrophic factor CD19 molecule CD86 molecule EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor accessory protein Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Kit Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Neurotrophin-3 Neurotrophin-4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proline rich 5 RPTOR independent companion of MTOR complex 2 Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tyrosine-protein kinase receptor Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MAV6 A0A8I3MIK8 A0A8I3MJG3 A0A8I3MM61 A0A8I3MN72 A0A8I3MP09 A0A8I3MPF4 A0A8I3MQS1 A0A8I3MQX7 A0A8I3MRL6 A0A8I3MT80 A0A8I3MVE7 A0A8I3MX71 A0A8I3MZ71 A0A8I3MZG1 A0A8I3N0H9 A0A8I3N488 A0A8I3N5M3 A0A8I3N8T5 A0A8I3N971 A0A8I3N9M7 A0A8I3NA65 A0A8I3NAC6 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NFQ7 A0A8I3NGY1 A0A8I3NH46 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NIT3 A0A8I3NKX5 A0A8I3NLT7 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NU74 A0A8I3NV07 A0A8I3NVK5 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NWK3 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P2V4 A0A8I3P3M1 A0A8I3P3X1 A0A8I3P4L9 A0A8I3P519 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PKX6 A0A8I3PMT9 A0A8I3PN81 A0A8I3PR42 A0A8I3PT69 A0A8I3PV99 A0A8I3PWT3 A0A8I3Q059 A0A8I3Q1C3 A0A8I3Q209 A0A8I3Q314 A0A8I3Q525 A0A8I3Q5L9 A0A8I3QXQ5 A0A8I3RPS3 A0A8I3RR99 A0A8I3RRT3 A0A8I3RSF1 A0A8I3RTN7 A0A8I3RYJ5 A0A8I3S0I1 A0A8I3S0T0 A0A8I3S333 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 A0A8I3SBF9 E2REX2 J9P0B3 J9P3I7 J9P8K0 O97799 O97863 P62999 P79150 Q06220 Q20FD0 Q6Q7I7 Q7YR73 Q867B7 Q9TQX1	AILIM AREG BDNF BTC CD19 CD28 CD80 CD86 EGF EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GRB2 HBEGF HGF ICOS IL1RAP IL33 IRAK1 IRAK4 IRS1 IRS2 KGF KIT KITLG KL KLB LCK LOC100856339 MAPKAP1 MET MGF MLST8 MTOR MYD88 NRG1 NRG2 NRG3 NTF3 NTF4 NTRK2 NTRK3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRR5 PTPN11 RAC1 RAC2 RHOG RICTOR SGK1 SRC STRN TGFA TRAF6 TRAT1 VAV1
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Beta-2-microglobulin C-type lectin domain-containing protein C-type lectin domain-containing protein GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Immunoglobulin subtype domain-containing protein Lymphocyte cytosolic protein 2 NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 TYRO protein tyrosine kinase-binding protein Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3MDD5 A0A8I3MGV8 A0A8I3MMK3 A0A8I3N971 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NUU1 A0A8I3NVH5 A0A8I3NZG2 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P6Q8 A0A8I3P7Z3 A0A8I3PNL2 A0A8I3PNS2 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PWV8 A0A8I3PXH7 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3S3N2 A0A8I3SCI7 P62999 Q38HS3	B2M BTK CD94 FYN GRAP2 GRB2 HRAS KLRD1 KLRK1 KRAS LAT LCK LCP2 LOC119863908 LOC119866326 NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PLCG2 RAC1 SHC1 SOS1 SYK TYROBP VAV2 VAV3

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