Tie2 Signaling
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- ANGPT1
- ANGPT2
- ANGPT4
- DOK2
- GRB14
- GRB2
- GRB7
- HRAS
- KRAS
- NRAS
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PTPN11
- SHC1
- SOS1
- TEK
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MET activates PI3K/AKT signaling
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- GAB1
- GRB2
- HGF
- MET
- PIK3CA
- PIK3R1
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IRS-mediated signalling
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- IRS1
- IRS2
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
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Costimulation by the CD28 family
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- AILIM
- BTLA
- GRB2
- ICOS
- ICOSLG
- LOC100856339
- PIK3CA
- PIK3R1
- PIK3R2
- PTPN11
- PTPN6
- TNFRSF14
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Keratinization
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- DSC1
- DSC3
- DSG1
- DSG2
- DSG3
- DSG4
- DSP
- JUP
- KER10
- KRT10
- KRT12
- KRT15
- KRT18
- KRT20
- KRT23
- KRT24
- KRT25
- KRT26
- KRT27
- KRT28
- KRT3
- KRT31
- KRT32
- KRT33B
- KRT34
- KRT35
- KRT36
- KRT37
- KRT38
- KRT39
- KRT40
- KRT41
- KRT72
- KRT73
- KRT74
- KRT75
- KRT76
- KRT77
- KRT78
- KRT80
- KRT81
- KRT82
- KRT83
- KRT84
- KRT85
- KRT9
- KRTAP11-1
- KRTAP24-1
- KRTAP3-1
- KRTAP8-1
- LOC100685322
- LOC100685403
- LOC100686265
- LOC100686358
- LOC102151268
- LOC102151404
- LOC102151604
- LOC102151831
- LOC102157302
- LOC119873184
- LOC610887
- PKP1
- PKP2
- PKP3
- PKP4
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Antimicrobial peptides
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- BPI
- BPIFA1
- BPIFA2
- BPIFB1
- BPIFB2
- BPIFB4
- BPIFB6
- CAMP
- CHGA
- CTSG
- ELA2
- ELANE
- GNLY
- LEAP2
- LOC100687463
- PGLYRP1
- PGLYRP2
- PI3
- PRSS2
- REG3A
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Post-translational modification: synthesis of GPI-anchored proteins
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- ALPI
- ALPL
- ART3
- ART4
- BST1
- CD109
- CD52
- CDW52
- CE5
- CEACAM1
- CEACAM20
- CNTN5
- CPM
- FCGR3A
- GLIPR2
- GP2
- GPIHBP1
- GPLD1
- HMCN2
- IZUMO1R
- LOC100683099
- LOC119875695
- LOC476816
- LOC478984
- LSAMP
- LY6D
- LY6E
- LY6G6C
- LY6G6D
- LY6H
- LYPD1
- LYPD3
- LYPD4
- LYPD5
- LYPD6B
- LYPD8
- MELTF
- NEGR1
- NRN1
- NRN1L
- NTM
- OPCML
- OTOA
- PLET1
- PRND
- PSCA
- RTN4RL1
- RTN4RL2
- SPACA4
- SPRN
- TECTA
- TECTB
- TEX101
- THY1
- VNN1
- XPNPEP2
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Activation of Matrix Metalloproteinases
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- CMA1
- COL18A1
- CTRB
- CTRB1
- CTSG
- CTSL
- CTSL1
- ELA2
- ELANE
- FURIN
- KLK1
- KLK2
- KLKB1
- MMP1
- MMP11
- MMP13
- MMP14
- MMP15
- MMP16
- MMP17
- MMP2
- MMP24
- MMP25
- MMP3
- MMP7
- MMP8
- MMP9
- PLG
- PRSS2
- SPOCK3
- TIMP1
- TIMP2
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Signaling by BMP
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- ACVR2A
- ACVR2B
- ACVRL1
- BMP10
- BMP2
- BMPR1A
- BMPR1B
- BMPR2
- CER1
- CHRDL1
- FSTL1
- GDF2
- GREM2
- INHA
- INHBA
- NOG
- SKI
- SMAD1
- SMAD4
- SMAD5
- SMAD6
- SMAD7
- SMAD9
- SMURF1
- SMURF2
- TGFBR3
- UBE2D1
- UBE2D3
- ZFYVE16
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Ub-specific processing proteases
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- ABCC7
- ADRB2
- ADRM1
- AR
- ARRB1
- ARRB2
- ATXN7
- AXIN1
- AXIN2
- BECN1
- BIRC2
- BIRC3
- CCNA1
- CCNA2
- CCP110
- CDC20
- CDC25A
- CDK16
- CFTR
- CLSPN
- CYLD
- FKBP8
- FOXO4
- GATA3
- H2AC1
- H2AC13
- H2AC14
- H2AC16
- H2AC19
- H2AC21
- H2AC25
- H2AC4
- H2AC6
- H2BC10
- H2BC15
- H2BC2
- H2BC21
- H2BC26
- H2BC3
- HGS
- HIF1A
- IDE
- IFIH1
- IKBKG
- IL33
- KAT2A
- KEAP1
- LOC100686569
- LOC100687259
- LOC100688437
- LOC119867694
- LOC119867696
- LOC119867718
- LOC119868881
- LOC119869165
- LOC119869175
- LOC119869178
- LOC119869187
- LOC119869258
- LOC119874734
- LOC482940
- MAP3K7
- MAT2B
- MDM2
- MDM4
- MMAC1
- MUL1
- MYC
- Madh3
- NFKBIA
- OTUB1
- POLB
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB5
- PSMB6
- PSMB7
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- PTEN
- PTRH2
- RCE1
- RHOT1
- RIPK1
- RNF123
- RNF128
- RNF146
- RPS27A
- RUVBL1
- SIAH2
- SMAD1
- SMAD2
- SMAD3
- SMAD7
- SMURF2
- STAM2
- SUDS3
- TAB1
- TADA2B
- TADA3
- TAF10
- TAF9B
- TGFBR1
- TNKS
- TNKS2
- TOMM20
- TOMM70
- TP53
- TRAF2
- TRAF6
- TRRAP
- UBA52
- UBB
- UBC
- UBCEP2
- USP10
- USP12
- USP13
- USP14
- USP15
- USP16
- USP18
- USP19
- USP2
- USP20
- USP21
- USP22
- USP26
- USP28
- USP3
- USP30
- USP33
- USP34
- USP37
- USP4
- USP42
- USP44
- USP47
- USP48
- USP49
- USP5
- USP7
- USP8
- VDAC1
- VDAC2
- VDAC3
- WDR20
- WDR48
- p53
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Ion homeostasis
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- ABCC9
- AHCYL1
- ASPH
- ATP1A1
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- CLIC2
- FXYD1
- FXYD2
- FXYD3
- FXYD4
- FXYD6
- FXYD7
- ITPR1
- ITPR2
- ITPR3
- KCNJ11
- LOC119880472
- NCX1
- NOS1
- PLN
- PRKACA
- RYR1
- RYR2
- RYR3
- SLC8A1
- SLC8A2
- SLC8A3
- SRI
- STIM1
- TNNI3
- TRDN
- TRPC1
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Stimuli-sensing channels
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- ANO1
- ANO2
- ANO3
- ANO4
- ANO5
- ANO6
- ANO7
- ANO8
- ANO9
- ASIC1
- ASIC2
- ASIC3
- ASIC4
- ASIC5
- ASPH
- BEST1
- BEST2
- BEST3
- BEST4
- BSND
- CALM2
- CLCA1
- CLCA2
- CLCA4
- CLCN1
- CLCN2
- CLCN4
- CLCN5
- CLCN6
- CLCN7
- CLCNK
- CLCNKA
- CLIC2
- LOC119880472
- NALCN
- NEDD4L
- OSTM1
- RAF1
- RPS27A
- RYR1
- RYR2
- RYR3
- SCNN1A
- SCNN1B
- SCNN1D
- SCNN1G
- SGK1
- SGK3
- SLC17A2
- SLC9B1
- SLC9B2
- SLC9C2
- SRI
- STOM
- STOML3
- TPCN1
- TPCN2
- TRDN
- TTYH1
- TTYH2
- TTYH3
- UBA52
- UBB
- UBC
- UBCEP2
- UNC79
- UNC80
- WWP1
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Transcriptional and post-translational regulation of MITF-M expression and activity
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- AIMP1
- AIMP2
- AKT3
- CREBBP
- DARS1
- EEF1E1
- EPRS1
- GSK3B
- IARS1
- KARS1
- KIT
- KITLG
- LARS1
- LOC100684571
- MAPK1
- MAPK3
- MARS1
- MGF
- MITF
- QARS1
- RARS1
- RPS6KA1
- SIRT1
- SOX10
- TBX3
- WNT3A
- XPO1
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Ion transport by P-type ATPases
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- ATP10A
- ATP10B
- ATP10D
- ATP11A
- ATP11B
- ATP11C
- ATP12A
- ATP13A1
- ATP13A2
- ATP13A4
- ATP13A5
- ATP1A1
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- ATP2C1
- ATP2C2
- ATP4A
- ATP4B
- ATP7A
- ATP7B
- ATP8A1
- ATP8A2
- ATP8B1
- ATP8B2
- ATP8B4
- ATP9A
- ATP9B
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- FXYD1
- FXYD2
- FXYD3
- FXYD4
- FXYD6
- FXYD7
- PDZD11
- PLN
- SRI
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Regulation of TNFR1 signaling
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- BIRC2
- BIRC3
- BIRC4
- CASP8
- CASP9
- CHUK
- CLIP3
- CYLD
- IKBKB
- IKBKE
- IKBKG
- IRF9
- MADD
- MIB2
- OPTN
- OTUD1
- OTUD7B
- RACK1
- RBCK1
- RIPK1
- RPS27A
- SPATA2
- SPPL2A
- SPPL2B
- STUB1
- TAX1BP1
- TBK1
- TNF
- TNFA
- TNFAIP3
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF2
- UBA52
- UBB
- UBC
- UBCEP2
- UBE2D1
- UBE2D2
- UBE2D3
- UBE2L3
- ULK1
- USP2
- USP21
- USP4
- XIAP
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TNFR1-induced NF-kappa-B signaling pathway
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- BIRC2
- BIRC3
- BIRC4
- CHUK
- CYLD
- IKBKB
- IKBKG
- IRF9
- MAP3K7
- OPTN
- OTUD1
- OTUD7B
- RACK1
- RBCK1
- RIPK1
- SPATA2
- TAB1
- TAB2
- TAB3
- TNF
- TNFA
- TNFAIP3
- TNFRSF1A
- TNFSF2
- TRADD
- TRAF2
- USP2
- USP21
- USP4
- XIAP
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Neurotransmitter receptors and postsynaptic signal transmission
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- GLRA1
- GLRA2
- GLRA3
- GLRB
- HTR3A
- HTR3B
- HTR3C
- HTR3E
- LOC478649
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Amino acid transport across the plasma membrane
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- SLC16A10
- SLC1A4
- SLC1A5
- SLC25A29
- SLC36A1
- SLC36A3
- SLC36A4
- SLC38A1
- SLC38A2
- SLC38A3
- SLC38A4
- SLC38A5
- SLC3A1
- SLC3A2
- SLC43A1
- SLC43A2
- SLC6A12
- SLC6A14
- SLC6A15
- SLC6A18
- SLC6A19
- SLC6A20
- SLC6A6
- SLC7A1
- SLC7A10
- SLC7A11
- SLC7A2
- SLC7A5
- SLC7A6
- SLC7A8
- SLC7A9
- SNX12
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Recycling of bile acids and salts
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- ABCC3
- ALB
- Abcb11e
- BAAT
- BSEP
- NCOA1
- NCOA2
- NR1H4
- RXRA
- SLC10A1
- SLC10A2
- SLC27A5
- SLC51A
- SLC51B
- SLCO1A2
- SLCO1B2
- SLCO1B3
- STARD5
- slc10a2
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Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
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- ACOT8
- ACOX2
- Abcb11e
- BAAT
- BSEP
- CYP27A1
- CYP7A1
- CYP7B1
- CYP8B1
- HSD17B4
- HSD3B7
- LOC119874618
- NCOA1
- NCOA2
- NR1H4
- RXRA
- SCP2
- SLC27A2
- SLC27A5
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Regulation of Complement cascade
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- C1QA
- C1QB
- C1QC
- C1R
- C1S
- C2
- C3
- C3AR1
- C5
- C5AR1
- C5AR2
- C6
- C7
- C8A
- C8B
- C8G
- C9
- CD19
- CD55
- CD59
- CD81
- CFB
- CFH
- CFHR5
- CFI
- CLU
- CPB2
- CPN1
- CPN2
- ELA2
- ELANE
- F2
- LOC102156626
- LOC481722
- LOC490269
- SEBOX
- SERPING1
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Initial triggering of complement
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- C1QA
- C1QB
- C1QC
- C1R
- C1S
- C2
- COLEC10
- FCN2
- LOC481722
- MASP1
- MASP2
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Apoptotic cleavage of cell adhesion proteins
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- CASP3
- CDH1
- CTNNB1
- DSG1
- DSG2
- DSG3
- DSP
- OCLN
- PKP1
- TJP1
- TJP2
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COPII-mediated vesicle transport
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- Alpha 1 antitrypsin
- Ankyrin repeat domain 28
- Bet1 golgi vesicular membrane trafficking protein
- Casein kinase I isoform delta
- Coagulation factor V
- Cornichon family AMPA receptor auxiliary protein 1
- Cornichon family AMPA receptor auxiliary protein 3
- Dipeptidyl peptidase 1
- EF-hand domain-containing protein
- EGF-like domain-containing protein
- Folate receptor alpha
- Gamma-soluble NSF attachment protein
- General vesicular transport factor p115
- Glutamate receptor
- Golgi SNAP receptor complex member 2
- Lectin, mannose binding 1 like
- Lectin, mannose binding 1
- Lectin, mannose binding 2 like
- MAC-inhibitory protein
- NSF attachment protein alpha
- NSF attachment protein beta
- Prolactin regulatory element-binding protein
- Protein SEC13 homolog
- Protein cornichon homolog 2
- Protein phosphatase 6 regulatory subunit 1
- Protein phosphatase 6 regulatory subunit 3
- Protein transport protein SEC23
- Protein transport protein Sec31A
- Protein transport protein sec16
- Protein transport protein sec16
- Ras-related protein Rab-1A
- SEC22 homolog A, vesicle trafficking protein
- SEC22 homolog B, vesicle trafficking protein
- SEC22 homolog C, vesicle trafficking protein
- SEC23 interacting protein
- SEC24 homolog A, COPII coat complex component
- SEC24 homolog B, COPII coat complex component
- SEC24 homolog C, COPII coat complex component
- SEC24 homolog D, COPII coat complex component
- SEC31 homolog B, COPII coat complex component
- Sec1 family domain containing 1
- Serine/threonine-protein phosphatase
- Small COPII coat GTPase SAR1B
- Syntaxin 17
- Syntaxin 5
- TBC1 domain family member 20
- Trafficking from ER to golgi regulator
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 2-like protein
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 6A
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 9
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Transmembrane emp24 domain-containing protein 10
- Transmembrane p24 trafficking protein 2
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Vesicle-fusing ATPase
- Vesicular integral-membrane protein VIP36
- YKT6 v-SNARE homolog
- cathepsin X
- small monomeric GTPase
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- ANKRD28
- AREG
- BET1
- CD59
- CNIH1
- CNIH2
- CNIH3
- CSNK1D
- CTSC
- CTSZ
- F5
- GOLGA2
- GORASP1
- GOSR2
- GRIA1
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- LOC119876190
- LOC609612
- MCFD2
- NAPA
- NAPB
- NAPG
- NSF
- PPP6C
- PPP6R1
- PPP6R3
- PREB
- RAB1
- RAB1A
- SCFD1
- SEC13
- SEC16A
- SEC16B
- SEC22A
- SEC22C
- SEC23A
- SEC23IP
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SEC31B
- SERPINA1
- STX17
- STX5
- TBC1D20
- TFG
- TGFA
- TMED10
- TMED2
- TRAPPC1
- TRAPPC10
- TRAPPC2
- TRAPPC2L
- TRAPPC3
- TRAPPC4
- TRAPPC6A
- TRAPPC6B
- TRAPPC9
- USO1
- YKT6
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Cargo concentration in the ER
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- AREG
- CD59
- CNIH1
- CNIH2
- CNIH3
- CTSC
- CTSZ
- F5
- GOSR2
- GRIA1
- LMAN1
- LMAN1L
- LMAN2
- LMAN2L
- LOC119876190
- LOC609612
- MCFD2
- MIA2
- PREB
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SERPINA1
- STX5
- TGFA
- TMED10
- TMED2
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