RAF/MAP kinase cascade
|
|
|
- ACTN2
- ANGPT1
- AREG
- BTC
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- CSF2
- CSF2RA
- CSF2RB
- DLG2
- DLG3
- DLG4
- EGF
- EGFR
- EPGN
- ERBB2
- ERBB3
- ERBB4
- EREG
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF19
- FGF20
- FGF22
- FGF23
- FGF3
- FGF3A
- FGF4
- FGF4B
- FGF4C
- FGF5
- FGF6
- FGF7
- FGF7A
- FGF7B
- FGF8
- FGF8B
- FGF9
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- FLT3
- FLT3LG
- FRS2
- FRS3
- FYN
- GDNF
- GFRA1
- GFRA2
- GFRA4
- GRB2
- GRIN1
- GRIN2B
- GRIN2D
- HBEGF
- HGF
- HRAS
- IL2
- IL2RA
- IL2RB
- IL3
- IL5
- IL5RA
- IRS1
- IRS2
- JAK1
- JAK2
- JAK3
- KGF
- KIT
- KITLG
- KL
- KLB
- KRAS
- LAT
- LRRC7
- MAPK1
- MAPK3
- MET
- MGF
- NCAM1
- NEFL
- NMDAR1
- NRAPGEP
- NRAS
- NRG1
- NRG2
- NRG3
- NRTN
- PDGFA
- PDGFB
- PDGFRA
- PDGFRB
- PDZGEF1
- PEA15
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PSPN
- PTK2
- PTPRA
- RALGDS
- RANBP9
- RAPGEF2
- RASGEF1A
- RASGRF1
- RASGRF2
- RASGRP1
- RASGRP3
- RASGRP4
- RET
- RGL1
- RGL2
- RGL3
- SHC1
- SHC2
- SHC3
- SOS1
- SPTA1
- SPTAN1
- SPTB
- SPTBN1
- SPTBN2
- SPTBN5
- TEK
- TGFA
|
|
EPHB-mediated forward signaling
|
|
|
- ACTB
- ACTG1
- ACTR2
- ACTR3
- ARHGEF28
- ARPC1A
- ARPC1B
- ARPC2
- ARPC3
- ARPC4
- ARPC5
- CDC42
- FYN
- GRIN1
- GRIN2B
- HRAS
- KALRN
- LOC119867035
- LYN
- NMDAR1
- PAK1
- PTK2
- RAC1
- RASA1
- RHOA
- ROCK1
- ROCK2
- SRC
- TIAM1
- WASL
- YES1
|
|
Stimuli-sensing channels
|
|
|
- ANO1
- ANO2
- ANO3
- ANO4
- ANO5
- ANO6
- ANO7
- ANO8
- ANO9
- ASIC1
- ASIC2
- ASIC3
- ASIC4
- ASIC5
- ASPH
- BEST1
- BEST2
- BEST3
- BEST4
- BSND
- CALM2
- CLCA1
- CLCA2
- CLCA4
- CLCN1
- CLCN2
- CLCN4
- CLCN5
- CLCN6
- CLCN7
- CLCNK
- CLCNKA
- CLIC2
- LOC119880472
- NALCN
- NEDD4L
- OSTM1
- RAF1
- RPS27A
- RYR1
- RYR2
- RYR3
- SCNN1A
- SCNN1B
- SCNN1D
- SCNN1G
- SGK1
- SGK3
- SLC17A2
- SLC9B1
- SLC9B2
- SLC9C2
- SRI
- STOM
- STOML3
- TPCN1
- TPCN2
- TRDN
- TTYH1
- TTYH2
- TTYH3
- UBA52
- UBB
- UBC
- UBCEP2
- UNC79
- UNC80
- WWP1
|
|
Glycosphingolipid catabolism
|
|
|
- ARSA
- ARSB
- ARSF
- ARSG
- ARSH
- ARSI
- ARSJ
- ARSK
- ARSL
- ASAH1
- ASAH2
- CTSA
- ENPP7
- GALC
- GBA1
- GBA2
- GBA3
- GLA
- GLB1
- GLB1L
- GLB1L2
- GM2A
- HEXA
- HEXB
- M6PR
- NEU1
- NEU2
- NEU3
- NEU4
- PSAP
- SMPD1
- SMPD2
- SMPD3
- SMPD4
- STS
- SUMF1
- SUMF2
- arsb
|
|
Regulation of actin dynamics for phagocytic cup formation
|
|
|
- ABI1
- ABI2
- ABL1
- ACTB
- ACTG1
- ACTR2
- ACTR3
- ARPC1A
- ARPC1B
- ARPC2
- ARPC3
- ARPC4
- ARPC5
- BAIAP2
- BTK
- CD247
- CD3G
- CDC42
- CRK
- CYFIP1
- CYFIP2
- DOCK1
- ELMO1
- ELMO2
- FCGR1A
- FCGR2B
- FCGR3A
- GRB2
- HSP90AA1
- HSP90AB1
- LIMK1
- LOC478984
- MAPK1
- MAPK3
- MYH2
- MYH9
- MYO10
- MYO1C
- MYO5A
- MYO9B
- NCK1
- NCKAP1
- NCKAP1L
- NCKIPSD
- NF2
- PAK1
- PTK2
- RAC1
- SYK
- VAV1
- VAV2
- VAV3
- WASF1
- WASF2
- WASF3
- WASL
- WIPF1
|
|
Ion transport by P-type ATPases
|
|
|
- ATP10A
- ATP10B
- ATP10D
- ATP11A
- ATP11B
- ATP11C
- ATP12A
- ATP13A1
- ATP13A2
- ATP13A4
- ATP13A5
- ATP1A1
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- ATP2C1
- ATP2C2
- ATP4A
- ATP4B
- ATP7A
- ATP7B
- ATP8A1
- ATP8A2
- ATP8B1
- ATP8B2
- ATP8B4
- ATP9A
- ATP9B
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- FXYD1
- FXYD2
- FXYD3
- FXYD4
- FXYD6
- FXYD7
- PDZD11
- PLN
- SRI
|
|
Ion channel transport
|
|
|
- ATP6AP1
- ATP6V0A1
- ATP6V0A2
- ATP6V0A4
- ATP6V0B
- ATP6V0C
- ATP6V0D1
- ATP6V0D2
- ATP6V0E1
- ATP6V1A
- ATP6V1B1
- ATP6V1B2
- ATP6V1C1
- ATP6V1C2
- ATP6V1D
- ATP6V1E1
- ATP6V1E2
- ATP6V1F
- ATP6V1G1
- ATP6V1G3
- ATP6V1H
- TCIRG1
|
|
Insulin receptor recycling
|
|
|
- ATP6AP1
- ATP6V0A1
- ATP6V0A2
- ATP6V0A4
- ATP6V0B
- ATP6V0C
- ATP6V0D1
- ATP6V0D2
- ATP6V0E1
- ATP6V1A
- ATP6V1B1
- ATP6V1B2
- ATP6V1C1
- ATP6V1C2
- ATP6V1D
- ATP6V1E1
- ATP6V1E2
- ATP6V1F
- ATP6V1G1
- ATP6V1G3
- ATP6V1H
- CTSD
- IDE
- INS
- INSR
- PTPN1
- PTPRF
- TCIRG1
|
|
Uptake of dietary cobalamins into enterocytes
|
|
|
- CBLIF
- CTRB
- CTRB1
- GIF
- LMBRD1
- LOC119869278
- PRSS2
- TCN1
|
|
Transport of RCbl within the body
|
|
|
- ABCC1
- CD320
- LDLRAP1
- LMBRD1
- LOC119869278
- LRP2
- MRP1
- TCN1
- TCN2
|
|
Ion homeostasis
|
|
|
- ABCC9
- AHCYL1
- ASPH
- ATP1A1
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- CALM2
- CAMK2A
- CAMK2B
- CAMK2G
- CLIC2
- FXYD1
- FXYD2
- FXYD3
- FXYD4
- FXYD6
- FXYD7
- ITPR1
- ITPR2
- ITPR3
- KCNJ11
- LOC119880472
- NCX1
- NOS1
- PLN
- PRKACA
- RYR1
- RYR2
- RYR3
- SLC8A1
- SLC8A2
- SLC8A3
- SRI
- STIM1
- TNNI3
- TRDN
- TRPC1
|
|
Regulation of insulin secretion
|
|
|
- ABCC8
- CACNA1A
- CACNA1C
- CACNA1D
- CACNA1E
- CACNA2D2
- CACNB2
- CACNB3
- KCNJ11
- PRKACA
- PRKACB
- RAPGEF3
- RAPGEF4
- SLC2A1
- SLC2A2
|
|
Hyaluronan biosynthesis and export
|
|
|
- ABCC5
- CEMIP
- HAS1
- HAS2
- HAS3
|
|
Platelet degranulation
|
|
|
- A1BG
- A2M
- ABCC4
- ACTG1
- ACTN1
- ACTN2
- AHSG
- ALB
- ALDOA
- ANXA5
- APLP2
- APOA1
- APOH
- APOOL
- APP
- Abcc4
- B9D2
- BRPF3
- CALM2
- CANT1
- CD109
- CD36
- CD63
- CD9
- CDC37L1
- CFD
- CHID1
- CLU
- CTSW
- CYB5R1
- CYRIB
- ECM1
- EGF
- ENDOD1
- F13A1
- F5
- F8VWF
- FAM3C
- FERMT3
- FLNA
- FN1
- GAS6
- GTPBP2
- HABP4
- HGF
- HRG
- IGF1
- IGF2
- IGFIA
- ISLR
- ITGA2B
- ITGB3
- ITIH3
- ITIH4
- KNG1
- LAMP2
- LEFTY1
- LGALS7B
- LHFPL2
- LOC100685620
- LOC102152706
- LOC119866770
- LOC490387
- LY6G6F
- MAGED2
- MANF
- NHLRC2
- OLA1
- PCDH7
- PCYOX1L
- PDGFA
- PDGFB
- PECAM1
- PHACTR2
- PLEK
- PLG
- PPBP
- PROS1
- PSAP
- QSOX1
- RARRES2
- SCCPDH
- SCG3
- SELENOP
- SELP
- SERPINA1
- SERPINA3
- SERPINA4
- SERPINE1
- SERPINF2
- SERPING1
- SOD1
- SPARC
- SPP2
- SRGN
- STXBP2
- SYTL4
- TAGLN2
- TEX264
- TGFB2
- TGFB3
- THBS1
- TIMP1
- TIMP3
- TLN1
- TMX3
- TUBA4A
- VCL
- VEGFA
- VEGFB
- VEGFC
- VEGFD
- VWF
- WDR1
|
|
The canonical retinoid cycle in rods (twilight vision)
|
|
|
- ABCA4
- CYP4V2
- DHRS9
- HSD17B6
- LRAT
- MYO7A
- RBP1
- RBP3
- RBP4
- RDH10
- RDH12
- RDH16
- RDH5
- RHO
- RLBP1
- RPE65
- SDR9C7
- STRA6
- TTR
|
|
Surfactant metabolism
|
|
|
- ABCA3
- ADGRF5
- ADORA2A
- ADRA2A
- ADRA2C
- CCDC59
- CKAP4
- CSF2RA
- CSF2RB
- CTSH
- GATA6
- LMCD1
- LOC610540
- NAPSA
- P2RY2
- PGA
- PGNA
- RDC8
- SFTPB
- SFTPC
- SFTPD
- SLC34A1
- SLC34A2
- TTF1
- ZDHHC2
|
|
Apoptotic cleavage of cellular proteins
|
|
|
- ACIN1
- APC
- BCAP31
- BIRC2
- BMX
- CASP3
- CASP6
- CASP7
- CASP8
- CLSPN
- PRKCD
- PRKCQ
- PTK2
- ROCK1
- SATB1
- STK24
- STK26
|
|
Cargo recognition for clathrin-mediated endocytosis
|
|
|
- AAK1
- ABCC7
- ADRB2
- AGFG1
- AGTR1
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- AREG
- ARRB1
- ARRB2
- AVP
- AVPR2
- BTC
- CBL
- CD3D
- CD3G
- CD4
- CFTR
- CHRM2
- CI-MPR/IGF2R
- CLTA
- CLTB
- CLTC
- CLTCL1
- COPS2
- COPS3
- COPS5
- COPS6
- COPS7A
- COPS7B
- COPS8
- DAB2
- DVL2
- EGF
- EGFR
- EPGN
- EPN1
- EPN2
- EPS15
- EPS15L1
- EREG
- FCHO1
- FCHO2
- FZD4
- GPS1
- GRB2
- GRK2
- GRK3
- HBEGF
- HGS
- IGF2R
- IL7R
- ITSN2
- KIAA0319
- LDLR
- LDLRAP1
- LOC102156511
- LOC119867035
- LRP2
- M6PR
- NECAP1
- NECAP2
- NEDD8
- PICALM
- REPS2
- RPS27A
- SCARB2
- SH3GL1
- SH3GL2
- SH3KBP1
- SLC18A3
- SLC2A8
- SNAP91
- STAM
- STAM2
- STON1
- STON2
- SYT1
- SYT11
- SYT2
- SYT8
- TACR1
- TGFA
- TGOLN2
- TOR1A
- TOR1B
- UBA52
- UBB
- UBC
- UBCEP2
- VAMP2
- VAMP3
- VAMP4
- VAMP7
- VAMP8
- WNT5A
|
|
VxPx cargo-targeting to cilium
|
|
|
- ARF4
- ASAP1
- CNGA2
- CNGA4
- CNGB1
- EXOC1
- EXOC2
- EXOC3
- EXOC4
- EXOC5
- EXOC6
- EXOC7
- EXOC8
- GBF1
- MEL
- PKD2
- RAB11
- RAB11A
- RAB11FIP3
- RAB3IP
- RAB8
- RAB8A
- RHO
|
|
MHC class II antigen presentation
|
- ADP-ribosylation factor
- AP complex subunit beta
- AP complex subunit sigma
- AP complex subunit sigma
- AP-1 complex subunit mu-1
- AP-1 complex subunit mu-2
- AP-2 complex subunit alpha
- AP-2 complex subunit alpha
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- Actin related protein 10
- Actin related protein 1B
- Alpha-centractin
- CD74 molecule
- Calnexin
- Carboxypeptidase
- Cathepsin B
- Cathepsin D
- Cathepsin E
- Cathepsin F
- Cathepsin O
- Cathepsin S
- Centromere protein E
- Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain domain-containing protein
- Clathrin heavy chain
- Clathrin light chain
- Cytoplasmic dynein 1 intermediate chain 2
- Dipeptidyl peptidase 1
- Dynactin subunit 1
- Dynactin subunit 2
- Dynactin subunit 3
- Dynactin subunit 4
- Dynactin subunit 5
- Dynactin subunit 6
- Dynein cytoplasmic 1 intermediate chain 1
- Dynein heavy chain, cytosolic
- Dynein light chain
- Dynein light chain
- Dynein light intermediate chain
- Dynein light intermediate chain
- F-actin-capping protein subunit alpha-2
- F-actin-capping protein subunit alpha
- F-actin-capping protein subunit alpha
- F-actin-capping protein subunit beta
- Gamma-interferon-inducible lysosomal thiol reductase
- HLA class II histocompatibility antigen, DO alpha chain-like
- Kinesin associated protein 3
- Kinesin family member 11
- Kinesin family member 26A
- Kinesin family member 4A
- Kinesin family member 5A
- Kinesin light chain
- Kinesin light chain
- Kinesin light chain
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Legumain
- Lymphocyte activating 3
- MHC class II DR alpha chain
- MHC class II antigen DM beta
- Major histocompatibility complex, class II, DM alpha
- Major histocompatibility complex, class II, DQ alpha 1
- Major histocompatibility complex, class II, DQ beta 2
- Oxysterol-binding protein
- Pro-cathepsin H
- Procathepsin L
- Protein SEC13 homolog
- Protein transport protein SEC23
- Protein transport protein Sec31A
- Queuine tRNA-ribosyltransferase catalytic subunit 1
- Rab interacting lysosomal protein
- Rac GTPase activating protein 1
- Ras-related protein Rab-7a
- SEC24 homolog A, COPII coat complex component
- SEC24 homolog B, COPII coat complex component
- SEC24 homolog C, COPII coat complex component
- SEC24 homolog D, COPII coat complex component
- SH3 domain containing GRB2 like 2, endophilin A1
- Small COPII coat GTPase SAR1B
- Spectrin beta chain
- Uncharacterized protein
- Uncharacterized protein
- dynamin GTPase
- dynamin GTPase
|
|
- ACTR10
- ACTR1A
- ACTR1B
- AP1B1
- AP1M1
- AP1M2
- AP1S1
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- ARF1
- CANX
- CAPZA2
- CAPZA3
- CAPZB
- CD74
- CENPE
- CLTA
- CLTC
- CTRN1
- CTSA
- CTSB
- CTSC
- CTSD
- CTSE
- CTSF
- CTSH
- CTSL
- CTSL1
- CTSO
- CTSS
- DCTN1
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DLA-DMA
- DLA-DMB
- DLA-DOA
- DLA-DQA1
- DLA-DRA
- DNM1
- DNM2
- DNM3
- DYNC1H1
- DYNC1I1
- DYNC1I2
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- HLA-DQB2
- IFI30
- KIF11
- KIF18A
- KIF20A
- KIF22
- KIF23
- KIF26A
- KIF2B
- KIF2C
- KIF3A
- KIF3C
- KIF4A
- KIF5A
- KIF5B
- KIFAP3
- KLC1
- KLC3
- KLC4
- LAG3
- LGMN
- LOC100856399
- LOC119868747
- LOC119876190
- LOC612266
- OSBPL1A
- PHLPP2
- QTRT1
- RAB7
- RAB7A
- RACGAP1
- RILP
- SEC13
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SH3GL2
- SPTBN2
|
|
MET receptor recycling
|
|
|
- ARF6
- CRK
- CRKL
- GAB1
- GGA3
- GRB2
- HGF
- MET
- RAB4A
- RAB4B
|
|
Post-translational modification: synthesis of GPI-anchored proteins
|
|
|
- ALPI
- ALPL
- ART3
- ART4
- BST1
- CD109
- CD52
- CDW52
- CE5
- CEACAM1
- CEACAM20
- CNTN5
- CPM
- FCGR3A
- GLIPR2
- GP2
- GPIHBP1
- GPLD1
- HMCN2
- IZUMO1R
- LOC100683099
- LOC119875695
- LOC476816
- LOC478984
- LSAMP
- LY6D
- LY6E
- LY6G6C
- LY6G6D
- LY6H
- LYPD1
- LYPD3
- LYPD4
- LYPD5
- LYPD6B
- LYPD8
- MELTF
- NEGR1
- NRN1
- NRN1L
- NTM
- OPCML
- OTOA
- PLET1
- PRND
- PSCA
- RTN4RL1
- RTN4RL2
- SPACA4
- SPRN
- TECTA
- TECTB
- TEX101
- THY1
- VNN1
- XPNPEP2
|
|
Aggrephagy
|
|
|
- ABCC7
- ARL13B
- CETN1
- CFTR
- DYNC1H1
- DYNC1I1
- DYNC1I2
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- HDAC6
- IFT88
- LOC119881719
- PARK7
- PCNT
- PRKN
- RPS27A
- UBA52
- UBB
- UBC
- UBCEP2
- UBE2N
|
|
RHOQ GTPase cycle
|
|
|
- ABCC7
- ARHGAP1
- ARHGAP17
- ARHGAP21
- ARHGAP26
- ARHGAP32
- ARHGAP33
- ARHGAP35
- ARHGAP5
- ARHGEF7
- ARL13B
- CAV
- CAV1
- CDC42
- CDC42BPA
- CDC42BPB
- CDC42EP1
- CDC42EP2
- CDC42EP3
- CFTR
- CPNE8
- CXNK1
- DEPDC1B
- DIAPH3
- DLC1
- FNBP1
- GFOD1
- GIT1
- GIT2
- GJA1
- GOPC
- GRLF1
- IQGAP3
- JUP
- LAMTOR1
- LOC119867035
- MPP7
- OPHN1
- P190A
- PAK1
- PAK2
- PAK4
- PLEKHG3
- PREX1
- RAB7
- RAB7A
- RHOQ
- SCRIB
- SLC1A5
- SLC4A7
- SNAP23
- SRGAP2
- STEAP3
- STOM
- SYDE1
- TFRC
- TRIP10
- VAMP3
- VANGL1
- WASL
- WWP2
- p190ARHOGAP
|
|
Clathrin-mediated endocytosis
|
|
|
- AAK1
- ABCC7
- ACTR2
- ACTR3
- ADRB2
- AGFG1
- AGTR1
- AMPH
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- APOB
- AREG
- ARF6
- ARFGAP1
- ARPC1A
- ARPC2
- ARPC3
- ARPC4
- ARPC5
- ARRB1
- ARRB2
- AVP
- AVPR2
- BIN1
- BTC
- CBL
- CD3D
- CD3G
- CD4
- CFTR
- CHRM2
- CI-MPR/IGF2R
- CLTA
- CLTB
- CLTC
- CLTCL1
- DAB2
- DNAJC6
- DNM1
- DNM2
- DNM3
- DVL2
- EGF
- EGFR
- EPGN
- EPN1
- EPN2
- EPS15
- EPS15L1
- EREG
- FCHO1
- FCHO2
- FNBP1
- FNBP1L
- FZD4
- GAK
- GAPVD1
- GRB2
- HBEGF
- HGS
- HIP1
- HIP1R
- IGF2R
- IL7R
- ITSN2
- KIAA0319
- LDLR
- LDLRAP1
- LOC102156511
- LOC119867035
- LOC607182
- LRP2
- M6PR
- NECAP1
- NECAP2
- OCRL
- PACSIN1
- PACSIN2
- PACSIN3
- PICALM
- PIK3C2A
- PIP5K1C
- QTRT1
- RAB5A
- RAB5B
- RAB5C
- REPS2
- RPS27A
- SCARB2
- SH3GL1
- SH3GL2
- SH3KBP1
- SLC18A3
- SLC2A8
- SNAP91
- SNX18
- SNX9
- STAM
- STAM2
- STON1
- STON2
- SYNJ1
- SYNJ2
- SYT1
- SYT11
- SYT2
- SYT8
- TACR1
- TGFA
- TGOLN2
- TRIP10
- UBA52
- UBB
- UBC
- UBCEP2
- VAMP2
- VAMP3
- VAMP4
- VAMP7
- VAMP8
- WASL
- WNT5A
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