GlyCosmos Portal

Bos taurus (cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (1341) Glycans (1011) Glycoproteins (1221) Lectins (76) Pathways (557)

Displaying entries **351 - 375** of **557** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	GlyTouCan ID
Interleukin-1 processing	Caspase 1 Gasdermin D Interleukin-1 alpha Interleukin-18 Multifunctional fusion protein NF-kappaB transcription factor p65 subunit NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Peptidase S1 domain-containing protein	A0A140T838 A0A3Q1MD51 A0A3Q1MFA5 A1XG22 A7MBB7 E1BAD2 F1MKW9 P08831 Q9TU73	CASP1 GSDMD IGIF IL18 IL1A IL1B LOC509956 NFKB1 NFKB2 RELA
Formation of the cornified envelope	Caspase 14 Corneodesmosin DSC1 protein Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoplakin Envoplakin Junction plakoglobin Kallikrein C Kallikrein related peptidase 12 Kallikrein related peptidase 13 Kallikrein related peptidase 14 Kallikrein related peptidase 8 Lipase family member J Lipase Lipase Lipase Peptidase inhibitor 3, skin-derived (SKALP) Periplakin Plakophilin 1 Plakophilin 4 Protein-glutamine gamma-glutamyltransferase K Repetin Serine peptidase inhibitor Kazal type 5 Serine peptidase inhibitor Kazal type 9 Serine protease inhibitor Kazal-type 6 Trichohyalin pancreatic elastase II	A0A3Q1LV63 A0A3Q1LZM5 A0A3Q1M4I0 A0A3Q1NK79 A1A4Q6 A6QR67 E1B9D7 E1B9N6 E1BA50 E1BE09 E1BGD9 E1BKC5 E1BKT9 E1BM91 E1BNT1 F1MBB7 F1MFC2 F1MGR5 F1MIW8 F1MJ11 F1MJH0 F1MSA3 F1MWJ0 F1MXJ3 F1MXS5 F1MZF2 F1N2K8 G3MVZ9 G3N156 G3X7H1 P01001 Q8SPJ1	CASP14 CDSN CELA2A DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP EVPL JUP KLK12 KLK13 KLK14 KLK5 KLK8 KLNC LIPJ LIPK LIPM LIPN PI3 PKP1 PKP4 PPL RPTN SPINK5 SPINK6 SPINK9 TCHH TGM1
Regulation of NF-kappa B signaling	Caspase 8 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase-interacting protein Leucine-rich repeat-containing protein 14 NEDD4-binding protein 1 NF-kappa-B essential modulator NLR family CARD domain containing 5 NLR family member X1 Polyubiquitin-B Polyubiquitin-C TNF receptor-associated factor 6 TNF receptor-associated factor Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1ME40 A2VE53 A5PJJ5 E1B9D9 E1B9F2 F1MUU5 P0CG53 P0CH28 P62992 P63048 Q0IIF7 Q2LGB8 Q3ZCC3 Q95KU9 Q95KV0 Q95KV1	CASP8 CHUK IKBIP IKBKB IKBKG IKIP IKKA LRRC14 N4BP1 NEMO NLRC5 NLRX1 RPS27A TRAF2 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP14
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	Catenin beta-1 Interferon regulatory factor 3 histone acetyltransferase histone acetyltransferase	E1B8D6 F1MD32 Q0VCX4 Q4JF28	CREBBP CTNNB1 EP300 IRF3
RUNX3 regulates WNT signaling	Catenin beta-1 Lymphoid enhancer binding factor 1 Runt-related transcription factor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7	A0A3Q1MAN6 A0A3Q1MG64 A0A3Q1MYL2 A0A3Q1MZ99 F1MJS2 Q0VCX4	CTNNB1 LEF1 RUNX3 TCF7 TCF7L1 TCF7L2
Trafficking and processing of endosomal TLR	Cathepsin B Cathepsin K Cathepsin S Endoplasmin Legumain Procathepsin L Protein canopy homolog 3 Toll like receptor 3 Toll like receptor 7 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A140T8D4 A0A3Q1MK24 A0A3S5ZPK8 A5H631 E1BBH4 P07688 P25326 P25975 Q0P5N1 Q5E968 Q95M18	CNPY3 CTSB CTSK CTSL CTSL1 CTSS GRP94 HSP90B1 HSPC4 LGMN TLR3 TLR7 TLR9 TRA1 UNC93B1
Insulin receptor recycling	Cathepsin D Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit	A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 A5PJB2 A6QQN2 A7MBJ4 E1BGJ7 E1BMV6 F1MMR6 F1MV64 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q24K02 Q28029 Q2KJB6 Q2TA24 Q32LB7	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CTSD IDE INS INSR LOC101904667 PTPN1 PTPRF TCIRG1 VATC VATF VPATPD
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Procathepsin L Serpin family B member 13	E1BIP8 P25975 Q5E968	CTSK CTSL CTSL1 SERPINB13
Estrogen-dependent gene expression	Cbp/p300-interacting transactivator 1 Core-binding factor subunit beta Cyclin-T1 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Estrogen receptor Forkhead box A1 GATA binding protein 3 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Growth regulating estrogen receptor binding 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone H2A.J Histone H2A.V Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A/H2B/H3 domain-containing protein Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B type 1 Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase Histone acetyltransferase Histone deacetylase 1 Lysine-specific histone demethylase Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 Progesterone receptor Prostaglandin E synthase 3 Ral transcription factor IIA subunit 1 Receptor protein-tyrosine kinase Runt-related transcription factor Sp1 transcription factor TATA-box-binding protein TLE family member 3, transcriptional corepressor Transcription initiation factor IIA subunit 2 Upstream stimulatory factor 1 Upstream transcription factor 2, c-fos interacting YY1 protein Zinc finger protein 217 [histone H3]-trimethyl-L-lysine(9) demethylase histone acetyltransferase histone acetyltransferase peptidylprolyl isomerase type I protein arginine methyltransferase	A0A3Q1LR26 A0A3Q1M5G9 A0A3Q1MBN5 A0A3Q1MF62 A0A3Q1MGB0 A0A3Q1MIR9 A0A3Q1MKB4 A0A3Q1MLT2 A0A3Q1MR38 A0A452DIU3 A0JNC9 A5D7T6 A5PJW8 E1B7Q6 E1B8D6 E1B8G9 E1B8U3 E1B9S8 E1BA41 E1BAD4 E1BH22 E1BHL3 E1BN65 E1BPY4 F1MBS5 F1MD32 F1MII0 F1ML22 F1MNS7 F1MU79 F1MUU9 F1MVD0 F1MZ35 F1N712 F2Z4C9 F2Z4F9 F2Z4H3 F2Z4J1 F2Z4J4 G3MXN4 G3MYB1 G3MZY8 G3N0C2 G3N0M9 G5E6I9 P49884 P62803 P62808 P68432 P84227 Q0VBX4 Q1JQ91 Q2HJ52 Q2KII5 Q2T9L9 Q32L01 Q32LA7 Q32P78 Q32P79 Q32PJ8 Q32S29 Q3T0Q3 Q3ZBC0 Q3ZBX9 Q5E9B8 Q5E9F8 Q5EA53 Q5EAB2 Q6T8E9 Q6XBT4 Q76LV1 Q76LV2 Q9BDI3	CBFB CCNT1 CDK9 CITED1 CREBBP EP300 ERBB4 ESR ESR1 FKBP4 FOXA1 GATA3 GREB1 GTF2A1 GTF2A2 GTF2F1 GTF2F2 H2AC12 H2AC18 H2AC21 H2AC6 H2AJ H2AV H2AZ2 H2B H2BC26 H2BC5 H3-3A H3-3B H3F3A H3F3B HDAC1 HIST1H2BI HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB KAT2B KAT5 KDM1A KDM4B LOC528006 MED1 MSG1 NCOA1 NCOA2 NCOA3 NR3A1 NR5A2 NRIP1 PGR POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2K POLR2L PRMT1 PTGES3 RUNX1 SP1 TBP TLE3 USF1 USF2 YY1 ZNF217
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 18 member A3 Solute carrier family 5 (Choline transporter), member 7 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 E1BIA1 E1BK36 F1MLQ5 F1N7B7 P11023 P32850 P48018 P61763 P63026 Q0IIL7 Q17QQ3 Q2KI26	CHAT CPLX1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC18A3 SLC5A7 SNAP25 STX1A STXBP1 SYB2 SYT1 UNC13B UNC18A VAMP2
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein Choline transporter-like protein Multidrug and toxin extrusion protein Solute carrier family 10 member 6 Solute carrier family 14 member 2 Solute carrier family 5 (Choline transporter), member 7 Urea transporter 1	A0A3Q1MWZ9 A0A452DJI9 A3KMY4 A5D7H3 A5PK40 E1BIP2 E1BP25 F1N5M4 Q2KI26 Q5QF96	CTL2 CTL3 CTL4 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 SLC47A2 SLC5A7 TPPT1 UT-B
Switching of origins to a post-replicative state	Chromatin licensing and DNA replication factor 1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 GMNN protein	A0A3Q1LHC9 A0A3Q1LIW5 A4FUD9 A6H7F8 E1BFZ9 E1BH89 Q3ZBH9 Q56JZ0	CDT1 GMNN MCM2 MCM3 MCM4 MCM5 MCM6 MCM7
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C Rho/Rac guanine nucleotide exchange factor 18 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M590 A0A3Q1MSP9 A0A3Q1N449 E1B9G8 F1MLS5 F1MYN2 F6RHP0 G3MZV8 O46680 P0CG53 P0CH28 P61585 P62992 P63048 Q9XT56	ARHA ARHGEF18 CGN F11R JAM1 PARD3 PARD6A PRKCZ RHO12 RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Organic anion transporters	Citrate transport protein Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial glutamate carrier 1 Sodium-coupled monocarboxylate transporter 1 Solute carrier family 17 member 1 Solute carrier family 17 member 5 Solute carrier family 17 member 8 Solute carrier family 25 member 10 Solute carrier family 5 member 5 Vesicular glutamate transporter 1 Vesicular glutamate transporter 2	A0A3Q1MTZ5 A4FV52 A6QLI1 C8KIL7 E1B7R3 E1BA07 F1MBS4 F1MT46 F1N6Z8 P22292 Q08DK4	GC1 SLC17A1 SLC17A5 SLC17A6 SLC17A7 SLC17A8 SLC20A4 SLC25A1 SLC25A10 SLC25A11 SLC25A22 SLC5A5 SLC5A8 SMCT1 VGLUT1 VGLUT2
Terminal pathway of complement	Clusterin Complement C5 Complement C7 Complement C8 alpha chain Complement component C8 beta chain Complement component C9	A0A3Q1LI40 F1MX87 F1MY85 F1N102 P17697 Q3MHN2	C5 C7 C8A C8B C9 CLU
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest specific 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S furin	A0A3Q1M616 A0A452DI66 A0A452DIP8 A1A4R0 B0JYR0 F1MBC5 F1MZ40 P07224 P22457	BGLAP F10 F2 F7 F9 FURIN GAS6 PROC PROS PROS1
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest specific 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A3Q1M616 A0A452DI66 A0A452DIP8 A1A4R0 F1MBC5 F1MZ40 P07224 P22457	BGLAP F10 F2 F7 F9 GAS6 PROC PROS PROS1
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Osteocalcin Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A3Q1M616 A0A452DI66 A0A452DIP8 A1A4R0 F1MBC5 P07224 P22457 Q07175	BGLAP F10 F2 F7 F9 GC GGCX PROC PROS PROS1
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	A0A3Q1NLA0 A0A452DIP8 F1MBC5 P22457 P30931	F10 F3 F7 F9 TFPI
Intrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VIII Coagulation factor X Coagulation factor XI Coagulation factor XII Complement component 1 Q subcomponent-binding protein, mitochondrial Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Kininogen 1 Plasma kallikrein Prolylcarboxypeptidase Prothrombin Serine protease inhibitor clade E member 2 Serpin family A member 5 Serpin family D member 1 Serpin family G member 1 Vitamin K-dependent protein C Vitamin K-dependent protein S von Willebrand factor	A0A140T8C8 A0A3Q1LT55 A0A3Q1M616 A0A452DHZ3 A0A452DI66 A0A452DIP8 E1B863 E1BG29 E1BMJ0 F1MAU4 F1MBC5 F1MTT3 F1N0R5 F1N1G4 F6R4P6 G5E5W1 P07224 Q2KJ63 Q3T0B6 Q8HZY1	C1QBP F10 F11 F12 F2 F7 F8 F9 GP1BB GP5 GP9 KLKB1 KNG1 PRCP PROC PROS PROS1 SERPINA5 SERPIND1 SERPINE2 SERPING1 VWF
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	Coagulation factor VIII Protein-S-isoprenylcysteine O-methyltransferase Protein-tyrosine sulfotransferase 2 Protein-tyrosine sulfotransferase protein-ribulosamine 3-kinase	G3N1V4 G5E5W1 Q08DH2 Q0P592 Q3SYY2	F8 FN3KRP ICMT TPST1 TPST2
Signaling by PDGF	Collagen alpha-1(IV) chain Collagen type VI alpha 1 chain Collagen type VI alpha 2 chain Collagen type VI alpha 3 chain Collagen type VI alpha 5 chain Collagen type VI alpha 6 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Secreted phosphoprotein 1 Thrombospondin 1 Thrombospondin 2 Thrombospondin 3 Thrombospondin 4 furin protein-tyrosine-phosphatase	A0A3Q1LXW3 A0A3Q1LZU0 A0A3Q1M0B4 A0A3Q1ME99 A0A3Q1MQV3 A0A3Q1MQX0 A0A3Q1N3Z8 A0A452DIF6 A0A452DJ62 A4IFC0 B0JYR0 B1H0W5 E1B726 E1BB91 E1BI98 E1BJY4 F1MD40 F1MKG2 F1N1W3 Q2KJ15 Q7SIB2	COL4A1 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 FURIN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PLAT PLG PTPN12 SPP1 THBS1 THBS2 THBS3 THBS4
Lectin pathway of complement activation	Collectin subfamily member 10 Collectin-11 Ficolin-2 MBL associated serine protease 1 MBL associated serine protease 2 Mannose-binding protein C	A0A3Q1MLF4 E1BJ49 F1MVS9 O02659 Q17QH6 Q5I2E5	COLEC10 COLEC11 FCN2 MASP1 MASP2 MBL	G49108TO G57321FI
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LJT8 A0A3Q1LK34 A0A3Q1M739 A0A3Q1M864 A2VE30 E1BBJ7 E1BCP6 E1BE66 E1BEL4 F1MDQ5 F1MH16 F1MXH7 F1MYM3 F1N0D6 F1N7C3 P05016 P11052 P23726 P23727 P32871 P49875 P52173 Q0IIE2 Q3T0F9 Q95118	CSF2 CSF2RB GAB2 GRB2 IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTPN6 SHC1 SOS1

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