GlyCosmos Portal

Bos taurus (cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (1341) Glycans (1011) Glycoproteins (1221) Lectins (76) Pathways (557)

Displaying entries **376 - 400** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	A0A452DI66 E1B863 E1BG29 F1N0R5 F1N1G4	F2 GP1BB GP5 GP9 VWF
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin, cytoplasmic 2 Albumin Alpha-1-acid glycoprotein Alpha-1-antiproteinase Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-4 Amyloid-beta A4 protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 C-X-C motif chemokine C-type lectin domain family 3 member B CD63 antigen CD9 antigen CYFIP-related Rac1 interactor B Calmodulin-like Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor VIII Coagulation factor XIII A chain Complement factor D EF-hand domain-containing protein ENDOD1 protein FIGF protein Fermitin family homolog 3 Fibronectin Filamin A Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine-rich repeat protein Insulin-like growth factor I Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Left-right determination factor Lymphocyte antigen 6 complex locus G6F Lysosomal associated membrane protein 2 MAGE family member D2 MICOS complex subunit MIC27 Mesencephalic astrocyte-derived neurotrophic factor Multimerin 1 NADH-cytochrome b5 reductase 1 NHL repeat-containing protein 2 NTR domain-containing protein Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Prosaposin Protein FAM3C Proteoglycan 1-like Protocadherin 7 Ras-related protein Rab-27B Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selenoprotein P Serotransferrin Serpin family G member 1 Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 Talin 1 Thrombospondin 1 Thymosin beta Torsin family 4 member A Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Transgelin-2 Tubulin alpha-4A chain Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vinculin Vitamin K-dependent protein S WD repeat domain 1 p-selectin protein disulfide-isomerase von Willebrand factor	A0A140T843 A0A140T897 A0A140T8C6 A0A140T8C8 A0A1L6ZA12 A0A3Q1LMG1 A0A3Q1LN74 A0A3Q1LTE4 A0A3Q1LUG2 A0A3Q1M2H1 A0A3Q1MHJ9 A0A3Q1MLQ7 A0A3Q1MQV3 A0A3Q1MR28 A0A3Q1N449 A0A3Q1N8P4 A0A452DIJ9 A0A452DIU4 A0A452DIX0 A4FV53 A4IF69 A4IFA6 A5D7D1 A5PK28 A5PKI3 A6H754 A6QL97 A6QLI2 A6QP91 A6QPF9 A7E3W2 A7MBB6 A7YY77 B1H0W5 E1B726 E1B8Z0 E1BBY0 E1BCK4 E1BH14 E1BMJ0 F1MD83 F1MGZ4 F1MHC2 F1MK25 F1MKS5 F1MLH6 F1MNQ4 F1MRZ8 F1MTN1 F1MTP5 F1MUC1 F1MW44 F1MX05 F1MY12 F1MZ40 F1MZD6 F1N0I3 F1N0R5 F1N169 F1N789 F6QVC9 F6RT22 G3X6N3 G3X7J5 G5E5A9 G5E5W1 G8JKY5 P00442 P07224 P07455 P07456 P12763 P13213 P15497 P15691 P17697 P21214 P26201 P28800 P30932 P34955 P49907 P56652 P63258 P80513 P81948 Q17QL4 Q27967 Q29RS5 Q2HJ33 Q2KJ15 Q2KJF1 Q2KJI3 Q32LP0 Q3B7N2 Q3MHW9 Q3SZ27 Q3T0A3 Q3ZC55 Q56K11 Q5E9F5 Q5EAB4 Q5GN72 Q8HZJ5 Q9XS49 Q9XS50 Q9XSK2	A1BG ACTG ACTG1 ACTN1 ACTN2 ACTN4 AGP AHSG ALB ALDOA ANXA5 APOA1 APOH APOL APP ARMET ARP BRPF3 CALM CD36 CD63 CD9 CDC37L1 CFD CHID1 CLEC3B CLU CTSW CYB5R1 CYRIB ENDOD1 F13A1 F5 F8 FAM121A FAM3C FAM49B FERMT3 FETUA FIGF FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 ILEI ISLR ITGA2B ITGB3 ITIH3 KIND3 KNG1 LAMP2 LEFTY2 LGALS3BP LHFPL2 LOC112442231 LOC515333 MAGED2 MANF MIC27 MMRN1 NHLRC2 OLA1 ORM1 PAS4 PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PI PLEK PLG PLI PPBP PROS PROS1 PSAP RAB27B RARRES2 SCCPDH SCG3 SELENOP SELP SERPINA1 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SPP24 SRGN STXBP2 SYTL4 TAGLN2 TF TGFB1 TGFB2 TGFB3 THBS1 TLN1 TMSB4X TMX3 TOR4A TUBA1 TUBA4A URP2 VCL VEGF VEGFA VEGFB VEGFC VEGFD VRF VWF WDR1 agp ly6g6f
Platelet homeostasis	P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase 2, cytoplasmic	E1B742 E1BIH1 E1BIP1 F1MUF3 F1MVZ6 F1N7A9 P79106 Q5E9U1	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase, tissue-nonspecific isozyme Alkaline phosphatase Alkaline phosphatase Alkaline phosphatase CAMPATH-1 antigen CPM protein Carcinoembryonic antigen related cell adhesion molecule 1 Carcinoembryonic antigen related cell adhesion molecule 1 Contactin 3 Contactin 4 Contactin-5 Doppel protein Folate receptor 2 (Fetal) Glycoprotein 2 Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 2 LY6/PLAUR domain containing 4 LY6/PLAUR domain containing 5 LY6/PLAUR domain containing 8 Low affinity immunoglobulin gamma Fc region receptor III-A Lymphocyte antigen 6 complex locus protein G6c Lymphocyte antigen 6 complex, locus E Lymphocyte antigen 6 family member H Lymphocyte antigen 6D MAM domain containing glycosylphosphatidylinositol anchor 1 MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein Melanotransferrin NAD(P)(+)--arginine ADP-ribosyltransferase NAD(P)(+)--arginine ADP-ribosyltransferase Neuritin Neuronal growth regulator 1 Neurotrimin Opioid-binding protein/cell adhesion molecule Otoancorin Pantetheinase Phosphatidylinositol-glycan-specific phospholipase D Placenta-expressed transcript 1 protein Prostate stem cell antigen Reticulon 4 receptor like 2 Reversion inducing cysteine rich protein with kazal motifs Serine protease 21 Shadow of prion protein Sperm acrosome membrane-associated protein 4 TEX101 protein Tectorin alpha Tectorin beta Thy-1 cell surface antigen UL16 binding protein 21 UL16-binding protein 17 ULBP13 Vanin 2 X-prolyl aminopeptidase 2 alkaline phosphatase alkaline phosphatase	A0A140T891 A0A3Q1LX90 A0A3Q1M3B5 A0A3Q1M7Z2 A0A3Q1MCB1 A0A3Q1MKY1 A0A3Q1MPP4 A0A3Q1MQ27 A0A3Q1MYV4 A0A452DIP5 A0A452DIY1 A0A452DJA6 A0JNL5 A0RZB4 A6QP04 A6QPE3 A6QQ36 A7MBD9 A7U7N6 E1B735 E1B7U4 E1B8I3 E1BCI6 E1BE12 E1BG25 E1BGM5 E1BI14 E1BJE3 F1MDR2 F1MHX8 F1MLP3 F1MNM2 F1MPH8 F1MQX6 F1MRK8 F1MTV3 F1MUR6 F1MZE6 F1N2M5 F1N3U5 F1N6T5 F1N726 F6RUZ4 G3MZX4 G3N030 G3N0F4 G3N2K2 G3X7K3 G5E5F5 G5E5L3 G5E5X5 P09487 P11834 P79107 Q09YM2 Q09YM5 Q0VCN9 Q148C3 Q1RMM2 Q29RK7 Q2KIC6 Q32PB3 Q3SX33 Q56JW8 Q58DA5	ALPI ALPL ART3 ART4 BST1 C15H11orf34 CD52 CEACAM1 CNTN3 CNTN4 CNTN5 CPM FCGR3 FCGR3A FCGRIII FOLR2 GP2 GPIHBP1 GPLD1 LOC100336941 LOC100850276 LOC516378 LOC528262 LOC783508 LSAMP LY6D LY6E LY6G6C LY6H LYPD1 LYPD2 LYPD4 LYPD5 LYPD8 MDGA1 MELTF NEGR1 NRN1 NT NTM OBCAM OCAM OPCML OTOA PRND PRSS21 PSCA RECK RTN4RL2 SPACA4 SPRN TECTA TECTB TEX101 THY1 ULBP13 ULBP17 ULBP21 VNN1 VNN2 XPNPEP2
Post-translational protein phosphorylation	APOL3 protein APOL3 protein Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antiproteinase Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid-beta A4 protein Anoctamin Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3 Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Complement component 4A Cystatin-C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20A golgi associated secretory pathway pseudokinase FAM20C golgi associated secretory pathway kinase Fibrillin-1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein ITIH2 protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Interleukin-6 Kinectin 1 Kininogen 1 LOC510193 protein Latent transforming growth factor beta binding protein 1 MBTPS1 protein MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Menin Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 NTR domain-containing protein Nucleobindin-1 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein shisa-5 Reticulocalbin 1 SERPINA10 protein SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family D member 1 Stanniocalcin-2 Syndecan-2 Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein ferroxidase von Willebrand factor A domain-containing protein 1	A0A140T881 A0A140T885 A0A140T897 A0A140T8C8 A0A140T8D3 A0A3Q1LIS3 A0A3Q1LMK4 A0A3Q1LRR3 A0A3Q1LUG2 A0A3Q1LVS2 A0A3Q1LZU0 A0A3Q1M2R2 A0A3Q1M616 A0A3Q1MB94 A0A3Q1MEX5 A0A3Q1MJT5 A0A3Q1N3Y2 A0A3Q1N5X6 A0A3Q1NAS1 A0A3Q1NC75 A0A3Q1NIX0 A0A452DHZ5 A0A452DII7 A0A452DJ03 A0A5H1ZRH6 A4FUZ9 A5D7R6 A5PJ69 A6QLI2 A6QP86 A6QPR4 A6QQR3 E1B8P3 E1BF93 E1BG25 E1BG36 E1BH06 E1BHJ7 E1BJF8 E1BJU2 E1BLA8 E1BNR0 F1MAZ4 F1MD94 F1ME65 F1MEA1 F1MI67 F1MJM1 F1MJW4 F1MKR5 F1MPP2 F1MRZ6 F1MVK1 F1MXX6 F1MY12 F1MZ40 F1N036 F1N076 F1N0I3 F1N444 F1N5H2 F2Z4E0 F6Q9Q9 F6QH94 F6QND5 F6QSG5 F6R4P6 F6RJ01 G3N2L2 G3N2W6 G3N348 G3X6N3 G3X724 G5E5A9 G5E5T0 O77836 P01035 P01211 P02817 P11116 P12763 P15497 P20616 P20959 P24591 P26892 P34955 P81282 P81644 P98133 Q05716 Q05717 Q08E55 Q0P5I0 Q10741 Q1LZE9 Q27967 Q28034 Q2KJH1 Q2UVX4 Q3SZ57 Q3T0A9 Q3ZBZ6 Q58D84 Q58DD4 Q6PX77 Q95M18	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APOA1 APOA2 APOA5 APOB APOE APOL3 APP BMP15 BMP4 BPIFB2 C3 C4A CALU CCN1 CDH2 CHGB CHGC CHRDL1 CKAP4 CP CSF1 CSPG2 CST3 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FETUA FGA FGF23 FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGFBP1 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC107131209 LOC112442231 LOC112446726 LOC510193 LOC515697 LOC518495 LOC521214 LOC524576 LOC531557 LOC786352 LOC788334 LTBP1 MADM MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MGAT4A MIA3 MXRA8 NUCB1 P4HB PDIA6 PENK PI PNPLA2 PRKCSH PROC PRSS23 RCN1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPIND1 SHISA5 SPARCL1 SPP1 SPP2 SPP24 STC2 TF TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase type 2 AKR1C4 protein ATP binding cassette subfamily B member 1 Albumin Corticosteroid-binding globulin Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostaglandin F synthase 2 UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A140T897 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1LZ03 A0A3Q1M423 A0A3Q1MB23 A0A3Q1MIN6 E1BBB3 E1BF81 E1BG58 E1BJU8 E1BP71 F1MFF6 F1MNC0 F1MT58 F1N3U0 G3X6I4 M0QW04 M0QW14 M0QW25 P52897 P52898 Q29RV2 Q3T047 Q3ZBG2	ABCB1 AKR1C4 ALB CBG CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 HSD11B2 LOC100138004 LOC100138908 LOC100296421 LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 SERPINA6 UGT1A6 UGT2B10
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A3Q1MKX0 E1B7B0 E1BNG2	MAN1A1 MAN1A2 MAN1C1	G70323CJ
Prostanoid ligand receptors	Prostaglandin D2 receptor 2 Prostaglandin D2 receptor Prostaglandin E receptor 1 Prostaglandin E receptor 2 Prostaglandin E2 receptor EP3 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Prostaglandin I2 receptor Thromboxane A2 receptor	A0A140T8B9 A0A3Q1N2W9 A0A452DI56 E1BQ27 F1MUY4 F1MZJ8 F1N2L8 P34979 Q95125	PTGDR PTGDR2 PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 CHMP4B protein Caspase 1 Caspase-13 Caspase-3 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 7 Chromatin modifying protein 4C Chromatin modifying protein 6 Cytochrome c Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 Interleukin-1 alpha Interleukin-18 Multifunctional fusion protein	A0A140T838 A0A3Q1MD51 A0A3Q1MFA5 A2VDY3 A6H704 E1BFC3 F1MB04 F1MTF4 G3MWP1 O02703 O75601 P08831 P10103 P62894 Q05KI7 Q08E32 Q148L0 Q2HJ35 Q3SX42 Q3T0U5 Q58CS7 Q9TU73	BAK1 BAX CASP1 CASP13 CASP3 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CYC CYCS ELANE GSDMD GSDME GZMB HMG1 HMGB1 IGIF IL18 IL1A IL1B VPS24
RAC1 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 Alsin Rho guanine nucleotide exchange factor ALS2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain-containing adapter protein 2 BCR activator of RhoGEF and GTPase C22H3ORF10 protein CDC42 effector protein (Rho GTPase binding) 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Chimaerin Chimaerin Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 1 Dedicator of cytokinesis 2 Dedicator of cytokinesis 3 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Dedicator of cytokinesis 9 Delta(14)-sterol reductase LBR Delta-like protein Diaphanous related formin 3 EMD protein Endoplasmic reticulum protein 27 FERM domain containing kindlin 2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 5 Family with sequence similarity 13 member A Family with sequence similarity 13 member B Family with sequence similarity 62 (C2 domain containing), member A G protein subunit alpha 13 GIT ArfGAP 1 GIT ArfGAP 2 GMIP protein Granule associated Rac and RHOG effector 1 HSPC321 protein IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IQGAP3 protein Integrin beta Kinectin 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Neuronal guanine nucleotide exchange factor Neutral amino acid transporter B(0) Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Nischarin Oligophrenin-1 P21 (RAC1) activated kinase 6 Par-6 family cell polarity regulator alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phosphoinositide-3-kinase regulatory subunit 3 Phospholipase Phospholipase Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G6 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase activating protein 1 Rac/Cdc42 guanine nucleotide exchange factor 6 Ragulator complex protein LAMTOR1 RalA binding protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 25 Rho GTPase activating protein 27 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho/Rac guanine nucleotide exchange factor 18 SH3 domain binding protein 1 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 2 SLIT-ROBO Rho GTPase activating protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase TAO3 Spermatogenesis associated 13 Synapse defective Rho GTPase homolog 2 Synaptobrevin homolog YKT6 Synaptosomal-associated protein T-cell activation GTPase activating protein TIAM Rac1 associated GEF 2 Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 protein kinase C receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LPH8 A0A3Q1LQ45 A0A3Q1LSY0 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LWZ4 A0A3Q1LX25 A0A3Q1LXW7 A0A3Q1M0G8 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M6Y9 A0A3Q1M7Q3 A0A3Q1MAP3 A0A3Q1MC59 A0A3Q1MD11 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MPX4 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRG4 A0A3Q1MRV3 A0A3Q1MT43 A0A3Q1MT94 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6F4 A0A3Q1N6J8 A0A3Q1NNR4 A0A452DHY1 A0A452DIS6 A0A452DJ82 A0JN43 A1A4I4 A2VDK6 A4FV18 A4IF90 A6H709 A6H7H0 A6QNS3 A6QQV8 A6QQZ7 A7MB21 A7YY57 A7Z037 A8YXX8 E1B7C4 E1B801 E1B876 E1B9G8 E1BA03 E1BAA4 E1BBA0 E1BBD2 E1BCC1 E1BDL7 E1BDN7 E1BDY4 E1BFF3 E1BGL2 E1BH05 E1BH51 E1BHQ9 E1BI41 E1BI70 E1BIG6 E1BIM5 E1BJ31 E1BJP2 E1BK77 E1BL56 E1BLB3 E1BM23 E1BMN2 E1BN47 E1BNA6 E1BNR7 E1BNV7 E1BPJ7 E1BPY0 E1BQ24 F1MBM9 F1MC48 F1MCL8 F1MDF3 F1MDQ5 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MHI2 F1MIX6 F1MIZ6 F1MJI3 F1MLS2 F1MM72 F1MMB0 F1MQ43 F1MRP8 F1MS60 F1MSF0 F1MSU8 F1MTN6 F1MTR1 F1MUW3 F1MWH1 F1MWH8 F1MWY5 F1MX60 F1MXR0 F1MY55 F1MZM7 F1N1J9 F1N1Q7 F1N2G5 F1N322 F1N348 F1N3L7 F1N657 F1N7C3 F1N7Q8 F6RHP0 F6RWK1 G3N2T3 G3N3C7 G5E580 G5E6P3 G5E6T2 O46521 O46522 P23726 P23727 P32871 P79132 Q08DA6 Q08DB1 Q08DN7 Q08DP6 Q08E52 Q0IIJ3 Q0P5E3 Q0VD41 Q17QW1 Q17QZ0 Q2KJ55 Q2KJ93 Q2T9M8 Q3SX08 Q3T000 Q3T0D8 Q5EAD0 Q95JC7	ABI1 ABI2 ABL2 ABR ALS2 AMIGO2 ARAP1 ARAP2 ARAP3 ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP15 ARHGAP17 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP25 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP9 ARHGDIA ARHGEF10 ARHGEF11 ARHGEF15 ARHGEF18 ARHGEF19 ARHGEF25 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 ASCT2 BAIAP2 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CDC42EP4 CHN1 CHN2 CYBA CYBB CYFIP1 CYFIP2 DEPDC1B DIAPH3 DLC1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EMD EPHA2 ERP27 ESYT1 FAM13A FAM13B FAM62A FARP1 FARP2 FERMT2 FGD5 GARRE1 GIT1 GIT2 GMIP GNA13 HSPC321 IQGAP1 IQGAP2 IQGAP3 ITGB1 JAG1 KTN1 L2HGDH LAMTOR1 LBR MCAM MCF2L MPP7 MYO9B NCF1 NCF2 NCF4 NCKAP1L NGEF NHS NISCH NOX1 NOX3 NOXO1 OPHN1 PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PARD6A PIK3CA PIK3R1 PIK3R2 PIK3R3 PKN PKN1 PKN2 PLD1 PLD2 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RALBP1 RASGRF2 RBM39 SH3BP1 SLC1A5 SNAP23 SOS1 SOS2 SPATA13 SRGAP1 SRGAP2 SRGAP3 SWAP70 SYDE2 TAGAP TAOK3 TFRC TIAM2 TRIO VANGL1 VAV1 VAV2 VAV3 VRK2 WASF1 WASF2 WASF3 YKT6
RAC2 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Ankyrin repeat and LEM domain containing 2 Armadillo repeat containing X-linked 3 BAR/IMD domain containing adaptor protein 2 like 1 BCR activator of RhoGEF and GTPase C22H3ORF10 protein CDC42 effector protein (Rho GTPase binding) 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 1 Dedicator of cytokinesis 2 Dedicator of cytokinesis 3 Dedicator of cytokinesis 4 Delta(14)-sterol reductase LBR Desmoglein 2 Diaphanous related formin 3 EMD protein Family with sequence similarity 62 (C2 domain containing), member A GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 HSPC321 protein IQ motif containing GTPase activating protein 1 Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Metaxin-1 NCK associated protein 1 like NHS actin remodeling regulator Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphoinositide-3-kinase regulatory subunit 3 Phospholipase Progesterone receptor membrane component 2 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase activating protein 1 Ragulator complex protein LAMTOR1 Ras-related C3 botulinum toxin substrate 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase TAO3 Sorting and assembly machinery component 50 homolog Starch binding domain 1 Synapse defective Rho GTPase homolog 1 Transferrin receptor protein 1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LKM4 A0A3Q1LLI7 A0A3Q1LNB6 A0A3Q1LPH8 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LWZ4 A0A3Q1LXL8 A0A3Q1M0G8 A0A3Q1M4M7 A0A3Q1M7Q3 A0A3Q1MFB9 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MPX4 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MT94 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6J8 A0A3Q1NNR4 A0A452DHY1 A0A452DJ82 A0JN43 A2VDK6 A2VDZ9 A6H709 A6QNS3 A6QQV8 A6QQZ7 A8YXX8 E1B7C4 E1B801 E1B876 E1B8X9 E1BAJ4 E1BBD2 E1BE36 E1BGL2 E1BHQ9 E1BI41 E1BIG6 E1BJ31 E1BJP2 E1BLB3 E1BMN2 E1BN47 E1BNR7 F1MC48 F1MDQ5 F1MFC2 F1MIX6 F1MLS2 F1MWH1 F1MXR0 F1MXU4 F1N1Q7 F1N7Q8 F6QJJ8 F6RWK1 O46521 O46522 P23726 P23727 P32871 P79132 Q08DN7 Q08E52 Q17QW1 Q17QZ0 Q2HJ55 Q2KJ93 Q3SX08 Q3T0D8 Q9TU25	ABI1 ABI2 ABR ANKLE2 ARHGAP1 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGDIA ARMCX3 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CDC42EP4 CYBA CYBB CYFIP1 DEPDC1B DIAPH3 DOCK1 DOCK10 DOCK2 DOCK3 DOCK4 DSG2 EMD EPHA2 ESYT1 FAM62A GARRE1 GIT1 GIT2 HSPC321 IQGAP1 ITGB1 LAMTOR1 LBR LMAN1 MCAM MPP7 MTX1 NCF1 NCF2 NCF4 NCKAP1L NHS OPHN1 PAK1 PAK2 PAK4 PGRMC2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PLD2 PREX1 RAC2 RACGAP1 RBM39 SAMM50 SLITRK5 STBD1 SWAP70 SYDE1 TAOK3 TFRC TRIO VANGL1 VAPB VAV1 VAV2 VAV3 VRK2 WASF2
RAC3 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain-containing adapter protein 2 BCR activator of RhoGEF and GTPase C22H3ORF10 protein Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Delta(14)-sterol reductase LBR Delta-like protein Desmoglein 2 Diaphanous related formin 3 EMD protein Endoplasmic reticulum protein 27 FERM domain containing kindlin 2 Family with sequence similarity 62 (C2 domain containing), member A GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 HSPC321 protein Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Neutral amino acid transporter B(0) Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Progesterone receptor membrane component 2 RAC3 protein RNA binding motif protein 39 Rac GTPase activating protein 1 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 3 SLIT and NTRK like family member 5 SLIT-ROBO Rho GTPase activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase TAO3 Starch binding domain 1 Synapse defective Rho GTPase homolog 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 phosphoinositide 5-phosphatase receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LPH8 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1LXN8 A0A3Q1M0G8 A0A3Q1M4M7 A0A3Q1M7Q3 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6J8 A0A452DHY1 A0A452DIS6 A0JN43 A2VDK6 A4IF90 A5PK69 A6H709 A6QNS3 A6QQV8 A6QQZ7 A7MB21 A8YXX8 E1B7C4 E1B801 E1B876 E1B8X9 E1BAA4 E1BAJ4 E1BBA0 E1BDN7 E1BFF3 E1BGL2 E1BHQ9 E1BI41 E1BIG6 E1BJ31 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BN47 E1BNR7 E1BPJ7 F1MBY5 F1MFC2 F1MLS2 F1MTN6 F1MWH1 F1MWH8 F1MXR0 F1MXU4 F1N1Q7 F1N348 F1N513 F1N6V1 F1N7Q8 F6QJJ8 F6RWK1 O46521 O46522 P23726 P23727 P79132 Q08E52 Q0IIJ3 Q17QW1 Q17QZ0 Q2KJ93 Q2T9M8 Q3SX08 Q3T000 Q3T0D8 Q5EAD0 Q95JC7	ABI1 ABI2 ABL2 ABR AMIGO2 ARAP2 ARAP3 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGAP5 ARHGAP6 ASCT2 BAIAP2 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CYBA CYBB CYFIP1 DEPDC1B DIAPH3 DOCK10 DSG2 EMD EPHA2 ERP27 ESYT1 FAM62A FERMT2 GARRE1 GIT1 GIT2 HSPC321 ITGB1 JAG1 LAMTOR1 LBR LMAN1 MCAM MPP7 NCF1 NCF2 NCF4 NCKAP1L NHS NOX1 NOX3 NOXO1 OCRL OPHN1 PAK1 PAK2 PAK4 PGRMC2 PIK3R1 PIK3R2 PREX1 RAC3 RACGAP1 RAPGEF1 RBM39 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 STBD1 SWAP70 SYDE1 TAOK3 TFRC TRIO VANGL1 VAV2 VRK2 WASF1 WASF2 YKT6
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase protein-serine/threonine phosphatase protein-serine/threonine phosphatase	A0A3Q1MLC5 A6QLS1 E1B8P9 E1BAA9 F1MEZ2 F1MI99 F1MM08 F1MQM7 P46196 Q0IID7 Q0VCY8 Q2KJ36	DUSP1 DUSP10 DUSP16 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK2 MAPK1 MAPK3 PEA15 PRKM1
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Betacellulin Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 EF-hand domain-containing protein Epiregulin Epithelial mitogen FLT3LG protein FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Focal adhesion kinase 1 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GTPase NRas Glial cell derived neurotrophic factor Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Kit ligand Klotho beta Klotho Linker for activation of T cells Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret RAS guanyl releasing protein 3 RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 3 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 RasGEF domain family member 1A Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 4 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A3Q1LI10 A0A3Q1LK34 A0A3Q1LNC8 A0A3Q1LRU7 A0A3Q1LSU3 A0A3Q1LUE0 A0A3Q1M0Y1 A0A3Q1M3Q3 A0A3Q1M6Z6 A0A3Q1M7J4 A0A3Q1MBH0 A0A3Q1MD11 A0A3Q1ME99 A0A3Q1MFJ1 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MKC7 A0A3Q1MPB6 A0A3Q1MPT9 A0A3Q1MR28 A0A3Q1N010 A0A3Q1N3Z8 A0A3Q1N508 A0A3Q1N8H3 A0A3Q1NAC7 A0A3Q1NAV6 A0A452DHX3 A0A452DJB1 A0JNB0 A0MTF4 A2VE24 A2VE27 A2VE30 A4IFA9 A5D7R9 A6H792 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BCP6 E1BD76 E1BDM2 E1BEL4 E1BFP8 E1BG59 E1BGY3 E1BHC1 E1BIN8 E1BJC7 E1BJU2 E1BKU1 E1BLT3 E1BM01 E1BMN5 E1BMX0 E1BP37 F1MCQ7 F1MEV4 F1MH16 F1MHC6 F1MJE0 F1MKE9 F1MLH6 F1MM66 F1MMQ8 F1MN51 F1MP52 F1MPD0 F1MRU0 F1MS00 F1MS28 F1MSG6 F1MXH7 F1MYE0 F1MYM3 F1MZ60 F1MZD6 F1N0D6 F1N4S9 F1N5N3 F1N6G8 F1N7C3 F2Z4J0 F6S0Q2 G3MXR4 G3MZM3 G3N104 G3XGD3 O18920 P02548 P03968 P03969 P05016 P11052 P23726 P23727 P32871 P46196 P49875 P52173 Q06807 Q0IIE2 Q0VCY4 Q0VCY8 Q28132 Q2HJF7 Q2KJ15 Q3MHJ9 Q3T0F9 Q3ZC55 Q95118 Z4YHD9	ACTN2 AFGF ANG1 ANGPT1 AREG ARTN BTC CALM CAMK2A CAMK2B CAMK2D CSF2 CSF2RB DLG1 DLG3 DLG4 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FRS3 FYN Fgf4 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 HBEGF HBGF-1 HGF IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KIT KITLG KL KLB KRAS LAT MAPK1 MAPK3 MET NEFL NRAPGEP NRAS NRG1 NRG2 NRG3 NRTN ODAD3 PDGFA PDGFB PDGFRA PDGFRB PDZGEF1 PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PTK2 PTPRA RALGDS RANBP9 RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP3 RASGRP4 RET RGL1 RGL2 RGL3 SCF SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 TEK TGFA TIE-2 TIE2
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin DOK4 protein Docking protein 1 Docking protein 2 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LNN8 A0A3Q1M0Y1 A0A3Q1M864 A0A3Q1MTG9 A0A3Q1N8H3 A0A452DJE2 A4IFA9 A4IFJ7 A5PKJ4 A6QLU3 A7MBB8 E1B7I9 E1BD76 E1BE66 E1BIM8 E1BKU1 F1MDQ5 F1MJE0 F1MP52 F1MRT5 F1MS00 F1MYF9 F1MYM3 F1N339 F1N7C3 F6S0Q2 G3MZM3 G3N3X9 G3X7B4 P00517 P23726 P23727 P32871 Q0IIE2 Q0VCR5 Q1RMW5 Q3SX40 Q3T0F9	ARTN DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB10 GRB2 GRB7 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PRKACA PRKACB PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein S100-A8 Protein S100-A9 Protein kinase C beta type Protein kinase C delta type Protein kinase C Ras-related C3 botulinum toxin substrate 2 mitogen-activated protein kinase non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1LTT9 A0A3Q1MKI4 A0A3Q1MRR6 A0A3Q1MSP9 A0A3Q1MTW8 A0A452DHY1 A6QLW1 E1B8P9 E1BAA4 E1BFF3 E1BPJ7 F1MHS5 G3X793 O46521 O46522 P05126 P28782 P46196 Q5BIN5 Q9TU25	CYBA CYBB ERK2 MAPK1 MAPK11 MAPK14 MAPK3 NCF1 NCF2 NCF4 NOX1 NOX3 NOXO1 PIK3C3 PIK3R4 PIN1 PRKCB PRKCB1 PRKCD PRKCZ PRKM1 RAC2 S100A8 S100A9
RHO GTPases activate IQGAPs	CAP-Gly domain containing linker protein 1 Cadherin-1 Calmodulin-like Catenin alpha 1 Catenin beta-1 Cell division control protein 42 homolog EF-hand domain-containing protein IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IQGAP3 protein Menin	A0A3Q1M9M0 A0A3Q1MQQ6 A0A3Q1MR28 A0A3Q1MSS6 A6H7H0 F1MC48 F1MLH6 F1MTR1 Q0P5I0 Q0VCX4 Q2KJ93	CALM CDC42 CDH1 CLIP1 CTNNA1 CTNNB1 IQGAP1 IQGAP2 IQGAP3 MEN1
RHOA GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Aladin WD repeat nucleoporin Anillin, actin binding protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 B-cell receptor-associated protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain-containing protein 115 Complement component 1 Q subcomponent-binding protein, mitochondrial DDRGK domain-containing protein 1 DEP domain containing 1B Dedicator of cytokinesis 2 Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 ER membrane protein complex subunit 3 Endoplasmic reticulum protein 27 FAS-associated factor 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 13 member A Flotillin-1 Flotillin-2 Formin like 3 GMIP protein IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Kinectin 1 Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G5 Pleckstrin homology and RhoGEF domain containing G6 Progesterone receptor membrane component 2 Proto-oncogene vav Protocadherin 7 Rac GTPase activating protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 19 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 28 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase activating protein 8 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho-GAP domain-containing protein Rho-associated protein kinase Rho/Rac guanine nucleotide exchange factor 18 Rhophilin-2 Rhotekin SLIT-ROBO Rho GTPase activating protein 1 STOM protein Sec1 family domain containing 1 Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 StAR related lipid transfer domain containing 8 Starch binding domain 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Syntaxin-5 T-cell activation GTPase activating protein TMEM87A protein Testis expressed 2 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA V-type proton ATPase subunit S1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B heme oxygenase (biliverdin-producing) non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LGT5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LX25 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA88 A0A3Q1MAP3 A0A3Q1MD11 A0A3Q1MEH9 A0A3Q1MFP5 A0A3Q1MN47 A0A3Q1MPX1 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DIS6 A0A452DJ82 A1A4I4 A2VDZ9 A4FUC9 A4FV18 A4FV22 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7YY57 A7Z038 A8E4P3 E1B718 E1B801 E1B9G8 E1BAJ4 E1BBA0 E1BBD2 E1BCC1 E1BCK4 E1BDL7 E1BDY4 E1BG76 E1BH05 E1BH51 E1BHQ9 E1BI70 E1BIG6 E1BIM3 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 E1BQ24 F1MBM9 F1MBT6 F1MC48 F1MCL8 F1MCN4 F1MEK6 F1MF50 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MGB9 F1MHI2 F1MIZ6 F1MJA6 F1MJH8 F1MK36 F1MLS2 F1MM72 F1MPJ6 F1MS34 F1MTN6 F1MTY9 F1MWY5 F1MYQ4 F1N1Q7 F1N2G5 F1N6V1 F1N7Q8 F6QCG0 F6QJJ8 F6RWK1 G3N2T3 G3X696 G5E6T2 P23726 P23727 P40682 P61585 P79132 Q08DA6 Q08DB1 Q08DB5 Q08DN7 Q08DN8 Q08DP6 Q2HJD0 Q2T9M8 Q3SZB5 Q3T000 Q3T0B6 Q3ZC07 Q3ZCB8 Q5E9F1 Q8SPJ1	AAAS ABCD3 ABR ACBD5 ACTC ACTC1 AKAP13 ANLN ARAP1 ARAP2 ARAP3 ARHA ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP18 ARHGAP19 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP26 ARHGAP28 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP6 ARHGAP8 ARHGAP9 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 ARHGEF7 ATP6AP1 ATP6IP1 ATP6S1 BCAP31 BCR C1QBP CAV1 CAVIN1 CCDC115 DAAM1 DDRGK1 DEPDC1B DIAPH1 DIAPH3 DLC1 DOCK2 EMC3 ERP27 FAF2 FAM13A FARP1 FLOT1 FLOT2 FMNL3 GMIP HMOX2 IQGAP1 IQGAP3 JUP KTN1 LBR LMAN1 MCAM MCF2L MYO9B NET1 NGEF OPHN1 PCDH7 PGRMC2 PIK3R1 PIK3R2 PKN PKN1 PKN2 PKN3 PLD1 PLEKHG3 PLEKHG5 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RASGRF2 RHO12 RHOA RHPN2 ROCK1 ROCK2 RTKN SCFD1 SLK SNAP23 SRGAP1 STARD13 STARD8 STBD1 STOM STX5 TAGAP TEX2 TFRC TJP2 TMEM111 TMEM87A TRIO UBXD8 VANGL1 VAPB VAV1 VAV2 VAV3 YKT6
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specific factor 7 Cullin 3 E3 ubiquitin-protein ligase BRE1A G protein pathway suppressor 1 Heterogeneous nuclear ribonucleoprotein C (C1/C2) RB binding protein 6, ubiquitin ligase RNA binding motif protein X-linked Rho related BTB domain containing 1 Rho-associated protein kinase Serine and arginine repetitive matrix 1 Serine/threonine-protein kinase 38 T-complex protein 1 subunit beta T-complex protein 1 subunit eta Thioredoxin like 1 Transformer-2 protein homolog beta Unconventional myosin-VI Vimentin cGMP-specific 3',5'-cyclic phosphodiesterase non-specific serine/threonine protein kinase	A0A3Q1ME43 A0A3Q1ME81 A0A3Q1MP80 A0A3Q1MW77 A0A498UZ20 A2VDP1 A2VDV2 D3JUI8 E1BCZ2 E1BIN5 F1MF50 F1MIH7 F1MU62 G3X736 P48616 Q28156 Q2NKZ1 Q3SX47 Q3SZA0 Q3ZBH0 Q3ZBT6	BRE1A CCT2 CCT7 COPS2 COPS4 CPSF7 CUL3 GPS1 HNRPC LOC782101 MYO6 PDE5 PDE5A RBBP6 RBMX RHOBTB1 RNF20 ROCK1 ROCK2 SFRS10 SRRM1 STK38 TRA2B TXNL1 VIM
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin 3 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoprotein C (C1/C2) Hsp90 co-chaperone Cdc37 Pleckstrin homology domain interacting protein RNA binding motif protein X-linked Rho-related BTB domain containing 2 Serine and arginine repetitive matrix 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin like 1 Transformer-2 protein homolog beta Tropomodulin 3 Twinfilin-1 Unconventional myosin-VI	A0A3Q1LL62 A0A3Q1ME81 A0A3Q1MP80 A0A3Q1NES9 A0A498UZ20 A2VDV2 D3JUI8 E1BIN5 F1MPF7 F1MZJ4 P63258 Q2NKZ1 Q3B7N2 Q3MHL7 Q3SX47 Q3T147 Q3ZBH0 Q3ZBT6 Q5EAC6 Q76LV1 Q76LV2	ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6A CCT7 CDC37 CUL3 DDX39B HNRPC HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB MYO6 PHIP RBMX RHOBTB2 SFRS10 SRRM1 STK38 TMOD3 TRA2B TWF1 TXNL1 UAP56
RHOC GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin, actin binding protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain containing 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Flotillin-1 Flotillin-2 Formin like 3 Formin-like protein 2 IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Rac GTPase activating protein 1 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rhotekin STOM protein Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 Syntaxin-5 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LSX9 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LWV5 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1MEH9 A0A3Q1MN47 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MW77 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DJ82 A1A4I4 A2VDZ9 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7Z038 A8E4P3 E1B718 E1B801 E1BH05 E1BHQ9 E1BIG6 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 F1MBT6 F1MC48 F1MCN4 F1MDL7 F1MEK6 F1MF50 F1MFK1 F1MIZ6 F1MJH8 F1MS34 F1N1Q7 F1N2G5 F1N7Q8 F6RWK1 G3X696 P23727 P61585 P79132 Q08DB5 Q08DN8 Q1RMJ6 Q3T0B6 Q8SPJ1	ABCD3 ABR ACBD5 AKAP13 ANLN ARHA ARHC ARHGAP1 ARHGAP18 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF5 BCR C1QBP CAV1 CAVIN1 DAAM1 DEPDC1B DIAPH1 DIAPH3 DLC1 FLOT1 FLOT2 FMNL2 FMNL3 IQGAP1 IQGAP3 JUP LBR LMAN1 LOC787891 MCAM MCF2L MYO9B OPHN1 PIK3R1 PKN PKN1 PKN2 PKN3 PREX1 PRK1 PRKCL1 RACGAP1 RHO12 RHOA RHOC ROCK1 ROCK2 RTKN SLK STARD13 STOM STX5 TFRC TJP2 VANGL1 VAPB VAV2
RHOD GTPase cycle	A-kinase anchoring protein 12 Adducin 3 Adenosine 5'-monophosphoramidase HINT2 Alpha-actinin-1 Anion exchange protein Ankyrin repeat and FYVE domain containing 1 CPNE8 protein Caveolin-1 DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 EF-hand domain-containing protein D2 EMD protein Family with sequence similarity 62 (C2 domain containing), member A Filamin A interacting protein 1 Golgin A2 Lamin B1 Lectin, mannose binding 1 Melanoma cell adhesion molecule Motile sperm domain containing 2 P21 (RAC1) activated kinase 6 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin A1 Plexin B1 Progesterone receptor membrane component 2 RNA binding motif protein 39 Rac GTPase activating protein 1 Ras homolog family member D Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 STEAP3 metalloreductase Starch binding domain 1 Torsin-1A-interacting protein 1 Vang-like protein Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A3Q1LLI7 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LTM9 A0A3Q1LUD9 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1M0A2 A0A3Q1M6Y9 A0A3Q1MD15 A0A3Q1MRR8 A0A3Q1MSA1 A0A3Q1MSB2 A0A3Q1MZP2 A0A3Q1N078 A0A3Q1NDE1 A0JN43 A2VDZ9 A5D784 A5D7A0 A6QQV8 E1B7F6 E1B801 E1BA03 E1BAJ4 E1BFR4 E1BHQ9 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNR7 F1MY55 F1N4E5 F1N7C7 F1N7Q8 F6QJJ8 F6RWK1 G3MWI1 P23726 P23727 P79132 Q3B7N2 Q3SX08 Q8SQ21	ACTN1 ADD3 AKAP12 ANKFY1 ARHGAP1 ARHGAP12 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 CAV1 CPNE8 DEPDC1B DIAPH1 DIAPH2 DIAPH3 EFHD2 EMD ESYT1 FAM62A FILIP1 GOLGA2 HINT2 LBR LMAN1 LMNB1 MCAM MOSPD2 PAK5 PAK6 PGRMC2 PIK3R1 PIK3R2 PLXNA1 PLXNB1 RACGAP1 RBM39 RHOD SLC4A7 STBD1 STEAP3 SWS1 TOR1AIP1 VANGL1 VAPB VRK2
RHOF GTPase cycle	A-kinase anchoring protein 12 Actin, cytoplasmic 1 Actin, cytoplasmic 2 Adducin 3 Alpha-actinin-1 Anion exchange protein BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain containing adaptor protein 2 like 2 Brain acid soluble protein 1 Caveolin-1 DEP domain containing 1B Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 169 member A Family with sequence similarity 62 (C2 domain containing), member A Lamin B1 Melanoma cell adhesion molecule Myosin IXB Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Rho GTPase activating protein 12 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase activating protein 2 STEAP3 metalloreductase SUMO specific peptidase 1 Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Torsin-1A-interacting protein 1 Vang-like protein	A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LUD9 A0A3Q1M6Y9 A0A3Q1MFX1 A0A3Q1MRR8 A0A3Q1MSB2 A0A3Q1NDE1 A0A452DIN5 A0JN43 E1BFE6 E1BHQ9 E1BLB3 E1BM23 E1BMN2 E1BNR7 E1BNV7 F1MFC6 F1MXR0 F1MXU4 F1N4E5 F1N5F9 F1N7Q8 F6RWK1 G3MWI1 P23726 P23727 P60712 P63258 P79132 P80724 Q2T9M8 Q3B7N2 Q3SZA1	ACTB ACTG ACTG1 ACTN1 ADD3 AKAP12 ARHGAP1 ARHGAP12 ARHGAP32 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 CAV1 DEPDC1B DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FAM62A FARP1 LMNB1 MCAM MTMR1 MYO9B NAP22 PIK3R1 PIK3R2 RHOF SENP1 SLC4A7 SNAP23 SRGAP2 STEAP3 SYDE1 TOR1AIP1 VANGL1
RHOH GTPase cycle	Anion exchange protein BRWD2 protein Caveolin-1 Endoplasmic reticulum protein 27 Family with sequence similarity 91 member A1 Glioblastoma amplified sequence Junction plakoglobin Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Oxysterol-binding protein P21 (RAC1) activated kinase 6 Ragulator complex protein LAMTOR1 Ral GTPase activating protein catalytic subunit alpha 1 Ras homolog family member H Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 3 Rho-associated protein kinase STOM protein Serine/threonine-protein kinase PAK 1 Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tyrosine-protein kinase CSK Tyrosine-protein kinase Tyrosine-protein kinase Vang-like protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4	A0A3Q1LSV4 A0A3Q1M0G8 A0A3Q1M346 A0A3Q1MW77 A0A452DIS6 A0A452DJ82 A6QLS8 A8E4P3 E1BA03 E1BIG6 E1BJC1 E1BMP9 E1BNR7 F1MF50 F1MQF4 F1MY55 F1N7X6 G3MWI1 G3X757 P11181 P79132 Q08E52 Q0II80 Q0VBZ0 Q17QZ0 Q3SWX4 Q3SZC4 Q3T0D8 Q3T0Q2 Q3ZCM0 Q8SPJ1 Q95JC7	ARHGDIA ARHGDIG ASCT2 BRWD2 CAV1 CSK DBT ERP27 FAM91A1 GBAS JUP LAMTOR1 LCK MTR NIPSNAP2 NSFL1C OSBPL11 PAK1 PAK2 PAK4 PAK5 PAK6 RALGAPA1 RHOH ROCK1 ROCK2 SLC1A5 SLC4A7 STOM TFRC TMEM59 VANGL1 VCP WDR11 ZAP70

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