Inactivation of CSF3 (G-CSF) signaling
|
|
|
- CSF3
- CSF3R
- CUL5
- ELOC
- GCSF
- JAK1
- JAK2
- LYN
- RNF7
- RPS27A
- SOCS1
- SOCS3
- SRC
- SYK
- TCEB1
- TCEB2
- TYK2
- UBA52
- UBA80
- UBB
- UBC
- UBC4
- UBCEP1
- UBCEP2
- UBCH4
- UBCH5B
- UBE2D1
- UBE2D2
- UBE2D3
|
|
Toll Like Receptor 10 (TLR10) Cascade
|
|
|
|
|
Lysosomal oligosaccharide catabolism
|
|
|
- LOC528518
- MAN2B1
- MAN2C1
- MANB
- MANBA
|
|
P2Y receptors
|
|
|
- GPR17
- LPAR4
- LPAR6
- P2RY1
- P2RY10
- P2RY11
- P2RY12
- P2RY14
- P2RY2
- P2RY4
- P2RY5
- P2RY6
|
|
Interleukin-35 Signalling
|
|
|
- CANX
- EBI3
- IL12A
- IL12RB2
- IL27RA
- IL6ST
- JAK1
- JAK2
- STAT1
- STAT3
- STAT4
- TYK2
- canx
|
|
Keratinization
|
- DSC1 protein
- Desmocollin 2
- Desmocollin 3
- Desmoglein 1
- Desmoglein 2
- Desmoglein 3
- Desmoglein 4
- Desmoplakin
- IF rod domain-containing protein
- IF rod domain-containing protein
- IF rod domain-containing protein
- IF rod domain-containing protein
- IF rod domain-containing protein
- IF rod domain-containing protein
- Junction plakoglobin
- KRT15 protein
- KRT32 protein
- KRT4 protein
- KRT82 protein
- KRTAP1-1 protein
- KRTAP4-7 protein
- Keratin 14
- Keratin 16
- Keratin 18
- Keratin 23
- Keratin 24
- Keratin 2
- Keratin 31
- Keratin 31
- Keratin 33A
- Keratin 36
- Keratin 37
- Keratin 39
- Keratin 3
- Keratin 77
- Keratin 79
- Keratin 83
- Keratin 84
- Keratin 85
- Keratin 86
- Keratin 9
- Keratin associated protein 19-5
- Keratin associated protein 3-1
- Keratin associated protein 8-1
- Keratin, type I cytoskeletal 10
- Keratin, type I cytoskeletal 17
- Keratin, type I cytoskeletal 19
- Keratin, type I cytoskeletal 20
- Keratin, type I cytoskeletal 25
- Keratin, type I cytoskeletal 26
- Keratin, type I cytoskeletal 27
- Keratin, type I cytoskeletal 28
- Keratin, type I cytoskeletal 40
- Keratin, type II cuticular Hb1
- Keratin, type II cytoskeletal 1
- Keratin, type II cytoskeletal 5
- Keratin, type II cytoskeletal 72
- Keratin, type II cytoskeletal 73
- Keratin, type II cytoskeletal 74
- Keratin, type II cytoskeletal 75
- Keratin, type II cytoskeletal 78
- Keratin, type II cytoskeletal 7
- Keratin, type II cytoskeletal 80
- Keratin, type II cytoskeletal 8
- Keratin-associated protein 10-8
- Keratin-associated protein 12-1-like
- Keratin-associated protein 12-1-like
- Keratin-associated protein 12-2
- Keratin-associated protein 3-3
- Keratin-associated protein 3-3
- Keratin-associated protein
- Keratin-associated protein
- Keratin-associated protein
- Keratin-associated protein
- LOC618938 protein
- LOC787225 protein
- Plakophilin 1
- Plakophilin 4
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
|
|
- DSC1
- DSC2
- DSC3
- DSG1
- DSG2
- DSG3
- DSG4
- DSP
- JUP
- KRT1
- KRT10
- KRT13
- KRT14
- KRT15
- KRT16
- KRT17
- KRT18
- KRT19
- KRT2
- KRT20
- KRT23
- KRT24
- KRT25
- KRT26
- KRT27
- KRT28
- KRT3
- KRT31
- KRT32
- KRT33A
- KRT36
- KRT37
- KRT39
- KRT4
- KRT40
- KRT5
- KRT6B
- KRT7
- KRT72
- KRT73
- KRT74
- KRT75
- KRT77
- KRT78
- KRT79
- KRT8
- KRT80
- KRT81
- KRT82
- KRT83
- KRT84
- KRT85
- KRT86
- KRT9
- KRTAP1-1
- KRTAP10-8
- KRTAP11-1
- KRTAP12-2
- KRTAP19-5
- KRTAP24-1
- KRTAP27-1
- KRTAP3-1
- KRTAP3-3
- KRTAP4-7
- KRTAP8-1
- LOC100294937
- LOC100300014
- LOC101902114
- LOC112442669
- LOC112446984
- LOC112448008
- LOC132346256
- LOC507184
- LOC616413
- LOC618359
- LOC618938
- LOC787051
- LOC787225
- LOC787600
- PKP1
- PKP4
|
|
Degradation of DVL
|
|
|
- ADRM1
- CUL3
- DACT1
- DVL1
- DVL2
- DVL3
- HECW1
- KLHL12
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- SUG1
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
G-protein activation
|
|
|
- GNA11
- GNA14
- GNA15
- GNAQ
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
- OPRM1
- PDYN
- POMC
|
|
UCH proteinases
|
|
|
- ACTB
- ACTL6A
- ACTR5
- ACTR8
- ADRM1
- ARP8
- ASXL1
- ASXL2
- BAP1
- BARD1
- CCDC95
- FOXK1
- FOXK2
- H2AC10
- H2AC18
- H2AC21
- H2AC25
- H2AC6
- H2AW
- HCFC1
- HIST3H2A
- INO80
- INO80B
- INO80C
- INO80D
- INO80E
- KDM1B
- LOC614881
- MBD5
- MBD6
- MCRS1
- NEDD8
- NFRKB
- OGT
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMB1
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB6
- PSMB7
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD6
- PSMD7
- PSMD8
- RPS27A
- RUVBL1
- SENP8
- SUG1
- TFPT
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UCH37
- UCHL1
- UCHL3
- UCHL5
- YY1
|
|
Macroautophagy
|
|
|
- AMBRA1
- APG4B
- ATG101
- ATG12
- ATG13
- ATG14
- ATG16L1
- ATG3
- ATG4A
- ATG4B
- ATG4C
- ATG4D
- ATG5
- ATG7
- ATG9
- ATG9A
- ATG9B
- AUT2B
- BECN1
- CHMP2A
- CHMP2B
- CHMP3
- CHMP4A
- CHMP4B
- CHMP4C
- CHMP6
- CHMP7
- DNCL1
- DYNLL1
- DYNLL2
- GABARAP
- GABARAPL1
- GABARAPL2
- GBL
- GEF2
- LAMTOR1
- LAMTOR2
- LAMTOR3
- LAMTOR4
- LAMTOR5
- LST8
- MAP1ALC3
- MAP1LC3
- MAP1LC3A
- MAP1LC3B
- MAP1LC3C
- MGC138057
- MLST8
- MTMR14
- MTOR
- PIK3C3
- PIK3R4
- PRKAA1
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- RB1CC1
- RHEB
- RPTOR
- RRAGA
- RRAGB
- RRAGC
- RRAGD
- SLC38A9
- TSC1
- ULK1
- UVRAG
- VPS24
- WDR45
- WDR45B
- WIPI1
- WIPI2
|
|
G alpha (q) signalling events
|
|
|
- ADRA1A
- ADRA1B
- ADRA1D
- ADRBK1
- AGT
- AGTR1
- ANXA1
- APP
- ARHGEF25
- AVP
- AVPR1A
- AVPR1B
- BDKRB2
- BRS3
- BTK
- CASR
- CCK
- CCKBR
- CHRM1
- CHRM3
- CHRM5
- CYSLTR1
- CYSLTR2
- EDN1
- EDN2
- EDN3
- EDNRA
- EDNRB
- F2
- F2R
- F2RL1
- F2RL2
- F2RL3
- FFAR2
- FFAR3
- FFAR4
- GAS
- GAST
- GCG
- GCGR
- GHRL
- GHSR
- GNA11
- GNA14
- GNA15
- GNAQ
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNGT1
- GNGT12
- GNGT2
- GNGT3
- GNGT5
- GNGT7
- GNGT8
- GNRH1
- GNRH2
- GNRHR
- GPR120
- GPR132
- GPR143
- GPR17
- GPR39
- GPR4
- GPR41
- GPR43
- GPR65
- GPR68
- GPR73L1
- GPR92
- GPRC2A
- GRK2
- GRM1
- GRM5
- GRP
- GRPR
- HCRTR1
- HCRTR2
- HTR2A
- HTR2B
- KISS1
- KISS1R
- KNG1
- LOC508666
- LPAR1
- LPAR2
- LPAR3
- LPAR4
- LPAR5
- LPAR6
- LTB4R
- LTB4R2
- MCHR1
- MCHR2
- MLNR
- NKA
- NKNA
- NKNB
- NMBR
- NMS
- NMUR1
- NMUR2
- NPFF
- NPFFR1
- NPFFR2
- NPS
- NPSR1
- NTS
- NTSR1
- NTSR2
- OPN4
- OXT
- OXTR
- P2RY1
- P2RY10
- P2RY11
- P2RY2
- P2RY5
- P2RY6
- PAFR
- PCAR1
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PKR2
- PLCB1
- PLCB4
- PMCH
- PROK1
- PROK2
- PROKR2
- PTAFR
- PTGER1
- PTGFR
- QRFP
- QRFPR
- RGS1
- RGS13
- RGS16
- RGS17
- RGS18
- RGS19
- RGS2
- RGS21
- RGS3
- RGS4
- RGS5
- RGSL1
- SERPINA8
- TAC1
- TAC2
- TAC2R
- TAC3
- TACR1
- TACR2
- TACR3
- TBXA2R
- TRH
- TRHR
- TRIO
- UTS2
- UTS2B
- XCL1
- XCL2
- XCR1
- mln
|
|
RHOBTB2 GTPase cycle
|
|
|
- ACTG
- ACTG1
- ACTN1
- BAT1
- CCT2
- CCT6A
- CCT7
- CDC37
- CUL3
- DDX39B
- HNRPC
- HSP90A
- HSP90AA1
- HSP90AB1
- HSPC3
- HSPCA
- HSPCB
- MYO6
- PHIP
- RBMX
- RHOBTB2
- SFRS10
- SRRM1
- STK38
- TMOD3
- TRA2B
- TWF1
- TXNL1
- UAP56
|
|
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
|
|
|
- CTNNB1
- HDAC1
- HINT1
- LEF1
- SIN3A
- TCF7
- TCF7L1
- TCF7L2
|
|
RAC2 GTPase cycle
|
|
|
- ABI1
- ABI2
- ABR
- ANKLE2
- ARHGAP1
- ARHGAP17
- ARHGAP26
- ARHGAP32
- ARHGAP35
- ARHGAP39
- ARHGAP42
- ARHGDIA
- ARMCX3
- BAIAP2L1
- BCR
- BORG5
- C22H3ORF10
- CAV1
- CDC42
- CDC42EP1
- CDC42EP4
- CYBA
- CYBB
- CYFIP1
- DEPDC1B
- DIAPH3
- DOCK1
- DOCK10
- DOCK2
- DOCK3
- DOCK4
- DSG2
- EMD
- EPHA2
- FAM62A
- GARRE1
- GIT1
- GIT2
- HSPC321
- IQGAP1
- ITGB1
- LAMTOR1
- LBR
- LMAN1
- MCAM
- MPP7
- MTX1
- NCF1
- NCF2
- NCF4
- NCKAP1L
- NHS
- OPHN1
- PAK1
- PAK2
- PAK4
- PGRMC2
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PLD2
- PREX1
- RAC2
- RACGAP1
- RBM39
- SAMM50
- SLITRK5
- STBD1
- SWAP70
- SYDE1
- TAOK3
- TFRC
- TRIO
- VANGL1
- VAPB
- VAV1
- VAV2
- VAV3
- VRK2
- WASF2
|
|
Phospholipase C-mediated cascade; FGFR2
|
|
|
- AFGF
- FGF1
- FGF10
- FGF16
- FGF17
- FGF18
- FGF2
- FGF20
- FGF23
- FGF3
- FGF4
- FGF4A
- FGF4C
- FGF5
- FGF5B
- FGF5C
- FGF6
- FGF6A
- FGF7
- FGF7B
- FGF8
- FGF9
- FGFA
- FGFR2
- Fgf4
- HBGF-1
- PLCG1
|
|
Organic anion transporters
|
|
|
- GC1
- SLC17A1
- SLC17A5
- SLC17A6
- SLC17A7
- SLC17A8
- SLC20A4
- SLC25A1
- SLC25A10
- SLC25A11
- SLC25A22
- SLC5A5
- SLC5A8
- SMCT1
- VGLUT1
- VGLUT2
|
|
Signaling by Activin
|
|
|
- ACTRII
- ACVR1B
- ACVR1C
- ACVR2
- ACVR2A
- ACVR2B
- ERK2
- INHA
- INHBA
- INHBB
- MAPK1
- MAPK3
- PRKM1
- SMAD2
- SMAD3
- SMAD4
- TGFBR3
|
|
MHC class II antigen presentation
|
- ADP-ribosylation factor 1
- AP complex subunit sigma
- AP-1 complex subunit beta-1
- AP-1 complex subunit gamma
- AP-1 complex subunit mu-1
- AP-1 complex subunit mu-2
- AP-1 complex subunit sigma-1A
- AP-1 complex subunit sigma-2
- AP-2 complex subunit alpha-2
- AP-2 complex subunit alpha
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- Actin-related protein 10
- Adaptor related protein complex 1 subunit beta 1
- Alpha-centractin
- BOLA-DQA1 protein
- Beta-centractin
- BoLA-DR-alpha
- CD74 molecule
- Calnexin
- Carboxypeptidase
- Cathepsin B
- Cathepsin D
- Cathepsin F
- Cathepsin K
- Cathepsin O
- Cathepsin S
- Centromere protein E
- Clathrin heavy chain 1
- Clathrin light chain A
- Cytoplasmic dynein 1 intermediate chain 1
- Dipeptidyl peptidase 1
- Dynactin subunit 1
- Dynactin subunit 2
- Dynactin subunit 3
- Dynactin subunit 4
- Dynactin subunit 5
- Dynactin subunit 6
- Dynamin-1
- Dynein heavy chain, cytosolic
- Dynein light chain 1, cytoplasmic
- Dynein light chain 2, cytoplasmic
- Dynein light intermediate chain
- Dynein light intermediate chain
- F-actin-capping protein subunit alpha-1
- F-actin-capping protein subunit alpha-2
- F-actin-capping protein subunit alpha
- Gamma-interferon-inducible lysosomal thiol reductase
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Ig-like domain-containing protein
- Kinesin family member 11
- Kinesin family member 15
- Kinesin family member 5A
- Kinesin light chain
- Kinesin light chain
- Kinesin light chain
- Kinesin light chain
- Kinesin-like protein KIF20A
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Kinesin-like protein
- Legumain
- Lymphocyte activating 3
- MHC class II DO-beta chain
- MHC class II antigen
- MHC class II antigen
- Major histocompatibility complex, class II, DM alpha
- Major histocompatibility complex, class II, DO alpha
- Major histocompatibility complex, class II, DY alpha
- Oxysterol-binding protein
- Pro-cathepsin H
- Procathepsin L
- Protein SEC13 homolog
- Protein transport protein SEC23
- Protein transport protein Sec24A
- Protein transport protein Sec31A
- Rab interacting lysosomal protein
- Rac GTPase activating protein 1
- SEC24 homolog B, COPII coat complex component
- SEC24 homolog C, COPII coat complex component
- SEC24 homolog D, COPII coat complex component
- SH3 domain containing GRB2 like 2, endophilin A1
- Small COPII coat GTPase SAR1B
- Spectrin beta chain
- dynamin GTPase
|
|
- ACTR10
- ACTR1A
- ACTR1B
- AP1B1
- AP1G1
- AP1M1
- AP1M2
- AP1S1
- AP1S2
- AP1S3
- AP2A1
- AP2A2
- AP2B1
- AP2M1
- AP2S1
- ARF1
- ARP10
- BLA-DQB
- BOLA-DMB
- BOLA-DQA1
- BOLA-DQA2
- BOLA-DQA5
- BOLA-DRA
- BOLA-DRB2
- BOLA-DRB3
- BOLA-DYA
- BoLA-DIB
- BoLA-DOB
- BoLA-DRA
- BoLA-DYB
- CANX
- CAPZA1
- CAPZA2
- CAPZA3
- CD74
- CENPE
- CLTA
- CLTC
- CTSA
- CTSB
- CTSC
- CTSD
- CTSF
- CTSH
- CTSK
- CTSL
- CTSL1
- CTSO
- CTSS
- DCTN1
- DCTN2
- DCTN3
- DCTN4
- DCTN5
- DCTN6
- DMB
- DNCL1
- DNM1
- DNM3
- DYB
- DYNC1H1
- DYNC1I1
- DYNC1LI1
- DYNC1LI2
- DYNLL1
- DYNLL2
- HLA-DMA
- HLA-DMB
- HLA-DOA
- HLA-DRA
- IFI30
- KIF11
- KIF15
- KIF20A
- KIF22
- KIF23
- KIF2B
- KIF3A
- KIF5A
- KIF5B
- KLC1
- KLC2
- KLC3
- KLC4
- LAG3
- LGMN
- LOC100848815
- OSBPL1A
- RACGAP1
- RILP
- SAR1B
- SEC13
- SEC13L1
- SEC23A
- SEC24A
- SEC24B
- SEC24C
- SEC24D
- SEC31A
- SH3GL2
- SPTBN2
- canx
|
|
ATF6 (ATF6-alpha) activates chaperones
|
|
|
|
|
The activation of arylsulfatases
|
|
|
- ARSA
- ARSB
- ARSE
- ARSG
- ARSH
- ARSI
- ARSK
- STS
- SUMF1
- SUMF2
|
|
TNFs bind their physiological receptors
|
|
|
- APRIL
- CD27
- CD70
- EDA
- EDAR
- EDARADD
- LOC768081
- LTA
- TNFB
- TNFRSF11B
- TNFRSF13B
- TNFRSF17
- TNFRSF1A
- TNFRSF1B
- TNFRSF25
- TNFRSF4
- TNFRSF6B
- TNFRSF8
- TNFRSF9
- TNFSF1
- TNFSF11
- TNFSF13
- TNFSF13B
- TNFSF14
- TNFSF15
- TNFSF4
- TNFSF8
- TNFSF9
- TNLG1B
- TNLG1D
- TNLG7A
- TNLG8A
|
|
VEGFR2 mediated cell proliferation
|
|
|
- KDR
- KRAS
- NRAS
- PDPK1
- PLCG1
- PRKCB
- PRKCB1
- PRKCD
- PRKCZ
- RASA1
- SPHK1
- SRC
- VEGF
- VEGFA
|
|
Sphingolipid de novo biosynthesis
|
|
|
- ABCC1
- ABCG2
- ADMP
- CERS1
- CERS2
- CERS3
- CERS4
- CERS5
- CERS6
- CERT
- CERT1
- COL4A3BP
- CSNK1G2
- CYB5B
- DEGS1
- DEGS2
- DES1
- FA2H
- LASS1
- LASS2
- LASS3
- LASS4
- MFSD2B
- MRP1
- ORMDL1
- ORMDL2
- ORMDL3
- OSBP
- PPM1L
- PRKD1
- PRKD2
- PRKD3
- SAMD8
- SGMS1
- SGMS2
- SPHK1
- SPHK2
- SPTLC1
- SPTLC2
- SPTSSA
- SPTSSB
- SSSPTA
- SSSPTB
- STARD11
- VAPA
- VAPB
|
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Multifunctional anion exchangers
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- SLC26A1
- SLC26A11
- SLC26A2
- SLC26A3
- SLC26A4
- SLC26A6
- SLC26A7
- SLC26A9
- SLC5A12
- SMCT2
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EPHB-mediated forward signaling
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- ACTB
- ACTG
- ACTG1
- ACTR2
- ACTR3
- ARHA
- ARHGEF28
- ARP2
- ARP3
- ARPC1A
- ARPC1B
- ARPC2
- ARPC3
- ARPC4
- ARPC5
- CDC42
- ITSN1
- PAK1
- PTK2
- RASA1
- RHO12
- RHOA
- ROCK1
- ROCK2
- SDC2
- WASL
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