GlyCosmos Portal

Bos taurus (domestic cattle)

Summary

Taxonomy ID: 9913
PubChem Taxonomy: 9913

Genes (2200) Glycans (1011) Glycoproteins (1220) Lectins (76) Pathways (548)

Displaying entries **201 - 225** of **548** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P19754	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAL
Digestion of dietary lipid	Carboxylic ester hydrolase Colipase Lipase Pancreatic lipase-related protein 2 Triacylglycerol lipase Triacylglycerol lipase	A0JNQ7 A5PK46 E1BJQ9 F1MC21 F1MES3 Q58DG4	CEL CLPS LIPF PNLIP PNLIPRP2 PNLIPRP3
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor	A0A452DI80 F1MCK3 F1N5C5 P41985	CHRM1 CHRM2 CHRM3 CHRM5
Vasopressin-like receptors	Arginine vasopressin Oxytocin receptor Oxytocin-neurophysin 1 Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin V2 receptor	A0A3Q1LXY0 F1ME85 F6PV87 P01175 P48044 P56449	AVP AVPR1A AVPR1B AVPR2 OXT OXTR
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	F1N6X2 F1N7B7 G3N354 P11023 P19120 P32850 P48018 P61763 P63026 Q0IIL7 Q0VCA1 Q17QQ3 Q29455	CPLX1 DNAJC5 GAD1 GAD2 HSC70 HSPA8 RAB3A RIMS1 SLC32A1 SNAP25 STX1A STXBP1 SYB2 SYT1 UNC18A VAMP2
PI3K Cascade	FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LQK4 A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M864 A0A3Q1MPT9 A0A3Q1NAV6 A0MTF4 A2VE24 A5H631 A6QLU3 A6QLW1 D8KXU9 E1B7I9 E1BAI2 E1BFP8 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MJE0 F1MN51 F1MRU0 F1MYE0 F1MYM3 F1N339 F1N4S9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P23726 P23727 P32871 Q3T0F9	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 Fgf4 GAB1 GAB2 GRB2 HBGF-1 IRS1 IRS2 KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9
Sialic acid metabolism	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Carboxypeptidase Gal-NAc6S Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acetylneuraminic acid phosphatase N-acylneuraminate cytidylyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Sialidase-1 Solute carrier family 17 member 5 Solute carrier family 35 (CMP-sialic acid transporter), member A1 Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A3Q1LM08 A0A3Q1LRX1 A0A3Q1LUC6 A0A3Q1LZS9 A0A3Q1MGH3 A0A3Q1N8K2 A0A3Q1NDQ7 A0A452DJ87 A0A452DJH9 A5D7T4 A5D960 A6BMK7 A7YWM8 E1B7R3 E1BMN0 F1MIL9 F1MRJ3 F1MVI9 F1MXN8 F1N2J4 F1N6V7 F1N7G6 G3N3B2 G5E5Q1 Q1RMX7 Q29RY9 Q3SZM5 Q3SZP1 Q6H8M7 Q6H8M9	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SIAT10 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 siat4B
COPI-dependent Golgi-to-ER retrograde traffic	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 ADP-ribosylation factor BCL2 interacting protein 1 Beta-soluble NSF attachment protein Centromere protein E Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-2 Coatomer subunit gamma Coatomer subunit zeta-1 Coatomer subunit zeta ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor Gamma-soluble NSF attachment protein Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Kinesin family member 11 Kinesin family member 13B Kinesin family member 15 Kinesin family member 16B Kinesin family member 1B Kinesin family member 1C Kinesin family member 20B Kinesin family member 21A Kinesin family member 21B Kinesin family member 26B Kinesin family member 5A Kinesin light chain Kinesin light chain Kinesin light chain Kinesin light chain Kinesin-like protein KIF20A Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein NBAS subunit of NRZ tethering complex NSF attachment protein alpha RAD50 interactor 1 Rac GTPase activating protein 1 Ras-related protein Rab-1A Surfeit locus protein 4 Syntaxin-18 TMED7 protein Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 9 Transmembrane p24 trafficking protein 3 Vesicle transport protein USE1 Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b ZW10, kinetochore associated, homolog (Drosophila) small monomeric GTPase	A0A140T856 A0A140T886 A0A3Q1LPC5 A0A3Q1LSE5 A0A3Q1LWK0 A0A3Q1LX75 A0A3Q1LXI8 A0A3Q1LYE2 A0A3Q1M0P4 A0A3Q1M5V0 A0A3Q1M736 A0A3Q1MF39 A0A3Q1MG61 A0A3Q1MIL7 A0A3Q1MMA1 A0A3Q1MN62 A0A3Q1MPX6 A0A3Q1MR65 A0A3Q1MWA3 A0A3Q1MWH8 A0A3Q1MXL6 A0A3Q1N141 A0A3Q1N147 A0JN39 A2VE21 A4IFP7 A4IFT6 A5PJR7 A6H7H2 A7YY49 E1BAT8 E1BC41 E1BC46 E1BF29 E1BG49 E1BGB0 E1BJK5 E1BJP2 E1BKE3 E1BMB8 E1BMC4 F1MI54 F1MJ53 F1MNK8 F1MWR7 F1N0Y3 F6Q334 F6QDZ3 F6RPS1 P33946 P35604 P35605 P53619 P81126 P84080 Q08DH4 Q0P5L6 Q17R07 Q28104 Q29RT6 Q2KJ37 Q3SZF2 Q3T133 Q5E971 Q5E9I6	ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 BNIP1 CENPE COPA COPB1 COPB2 COPD COPE COPE1 COPG1 COPG2 COPZ COPZ1 COPZ2 GBF1 KDELR KDELR1 KDELR2 KDELR3 KIF11 KIF12 KIF13B KIF15 KIF16B KIF18B KIF1B KIF1C KIF20A KIF20B KIF21A KIF21B KIF22 KIF23 KIF25 KIF26B KIF28 KIF2B KIF3A KIF5A KIF5B KLC1 KLC2 KLC3 KLC4 NAPA NAPB NAPG NBAS NSF RAB1A RAB1B RACGAP1 RINT1 SEC22B SNAPB STX18 SURF4 TMED10 TMED3 TMED7 TMED9 TMP21 USE1 ZW10
COPI-mediated anterograde transport	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 1 ADP-ribosylation factor 3 ADP-ribosylation factor 4 ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 ADP-ribosylation factor Actin-related protein 10 Alpha-centractin BET1-like protein Bet1 golgi vesicular membrane trafficking protein Beta-soluble NSF attachment protein CD55 molecule CD59 glycoprotein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma-2 Coatomer subunit gamma Coatomer subunit zeta-1 Coatomer subunit zeta Conserved oligomeric Golgi complex subunit 1 Conserved oligomeric Golgi complex subunit 2 Conserved oligomeric Golgi complex subunit 3 Conserved oligomeric Golgi complex subunit 4 Conserved oligomeric Golgi complex subunit 5 Conserved oligomeric Golgi complex subunit 6 Conserved oligomeric Golgi complex subunit 7 Conserved oligomeric Golgi complex subunit 8 Cytoplasmic dynein 1 intermediate chain 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein heavy chain, cytosolic Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain ER lumen protein-retaining receptor 1 ER lumen protein-retaining receptor 2 ER lumen protein-retaining receptor F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Folate receptor-like domain-containing protein Gamma-soluble NSF attachment protein General vesicular transport factor p115 Golgi SNAP receptor complex member 1 Golgi SNAP receptor complex member 2 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Golgi reassembly stacking protein 1 Golgin A2 Golgin B1 Insulin NSF attachment protein alpha Ras-related protein Rab-1A Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta chain Synaptobrevin homolog YKT6 Syntaxin-5 TMED7 protein Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 9 Transmembrane p24 trafficking protein 3 Transmembrane protein 115 Vesicle-fusing ATPase small monomeric GTPase	A0A140T856 A0A140T886 A0A3Q1LNC8 A0A3Q1LQX2 A0A3Q1LSE5 A0A3Q1LTM9 A0A3Q1LWK0 A0A3Q1LXI8 A0A3Q1LYE2 A0A3Q1M072 A0A3Q1M3Y3 A0A3Q1M5V0 A0A3Q1M762 A0A3Q1MJE3 A0A3Q1MUW5 A0A3Q1MWA3 A0A3Q1N147 A0A3Q1NDZ1 A0A3Q1NEU9 A0A452DKB6 A0JN39 A2VE21 A4FUA8 A4FUB8 A4IFP7 A4IFT6 A5PJB2 E1BBI8 E1BGA6 E1BJK5 E1BK29 E1BKZ5 E1BLT3 E1BMC4 E1BMN5 F1MBQ0 F1MI54 F1MKE9 F1MLE3 F1MMQ8 F1MQ89 F1N5R4 F2Z4F0 F6Q334 G3N173 P33946 P35604 P35605 P41541 P53619 P61285 P81126 P84080 Q08DB5 Q0P5A1 Q148G7 Q17R07 Q28104 Q29RQ3 Q2KII9 Q2KJ37 Q2TBU3 Q32KS3 Q32PA1 Q3MHG0 Q3MHP8 Q3MHR3 Q3SZF2 Q3T000 Q3T133 Q3ZBD2 Q3ZCF0 Q5E971 Q5E997 Q5E9I6	ACTR10 ACTR1A ARCN1 ARF1 ARF3 ARF4 ARF5 ARFGAP1 ARFGAP2 ARFGAP3 ARP10 BET1 BET1L CAPZA1 CAPZA2 CAPZA3 CD55 CD59 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 COPA COPB1 COPB2 COPD COPE COPE1 COPG1 COPG2 COPZ COPZ1 COPZ2 DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DNCL1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 FOLR3 GBF1 GOLGA2 GOLGB1 GORASP1 GOSR1 GOSR2 INS KDELR KDELR1 KDELR2 KDELR3 NAPA NAPB NAPG NSF RAB1A RAB1B SNAPB SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 STX5 TMED10 TMED3 TMED7 TMED9 TMEM115 TMP21 USO1 VDP YKT6
Digestion	Guanylate cyclase activator 2B Guanylate cyclase Guanylin PIR protein alkaline phosphatase	A6QQH1 E1BIM0 E1BIM1 E1BJE3 F1N5B2	GUCA2A GUCA2B GUCY2C LOC516378 PIR
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2
FRS-mediated FGFR1 signaling	FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 Klotho SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 A5D7R9 A6H792 D8KXU9 E1B7I9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BMX0 E1BP37 F1N339 F1N6G8 F1N7C3 G3MXR4 G3XGD3 P03968 P03969 Q3T0F9	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 FRS2 FRS3 Fgf4 GRB2 HBGF-1 KL KRAS NRAS PTPN11 SOS1
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides Growth factor receptor-bound protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Proto-oncogene vav SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LKV0 A0A3Q1M535 A0A3Q1M739 A0A3Q1M839 A0A3Q1MFU0 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1N7P8 A0A3Q1NI55 A0A3Q1NIZ6 A0A3S5ZPA3 E1BE66 E1BKE7 F1MMQ7 F1MX21 F1N586 F1N7C3 G5E513 P23727 P40293 Q08DN7 Q08DV4 Q1LZB2 Q3T0F9 Q3ZC95	BLNK BTK CD19 CD22 CD79A CD79B DAPP1 GRB2 IGA ITPR1 ITPR2 ITPR3 MB-1 NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1
Transcriptional regulation by RUNX2	Core-binding factor subunit beta Cyclin-dependent kinase 1 Cyclin-dependent kinase 4 G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Protein phosphatase, Mg2+/Mn2+ dependent 1D Runt-related transcription factor SRY-box transcription factor 9	A0A3Q1MKY5 A0A3Q1MN22 A0A452DIV3 E1B9S8 E1BD03 P48734 Q1LZG6 Q32KY4	CBFB CCNB1 CCND1 CDC2 CDK1 CDK4 CDKN1 PPM1D RUNX2 SOX9
Thyroxine biosynthesis	Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 NAD(P)H oxidase (H2O2-forming) NAD(P)H oxidase (H2O2-forming) Solute carrier family 5 member 5 Thyroid peroxidase Thyrotropin subunit beta	A0A3Q1M790 A0A3S5ZPC4 E1BMK1 E1BMS3 F1MT46 P01217 P01223	CGA DUOX1 DUOX2 IYD SLC5A5 TPO TSHB
RHOH GTPase cycle	Anion exchange protein BRWD2 protein Caveolin-1 Endoplasmic reticulum protein 27 Family with sequence similarity 91 member A1 Glioblastoma amplified sequence Junction plakoglobin Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Oxysterol-binding protein P21 (RAC1) activated kinase 6 Ragulator complex protein LAMTOR1 Ral GTPase activating protein catalytic subunit alpha 1 Ras homolog family member H Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 3 Rho-associated protein kinase 2 Rho-associated protein kinase STOM protein Serine/threonine-protein kinase PAK 1 Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tyrosine-protein kinase CSK Tyrosine-protein kinase Tyrosine-protein kinase Vang-like protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4	A0A3Q1LSV4 A0A3Q1M0G8 A0A3Q1M346 A0A3Q1MW77 A0A452DIS6 A0A452DJ82 A6QLS8 A8E4P3 E1BA03 E1BIG6 E1BJC1 E1BMP9 E1BNR7 F1MF50 F1MQF4 F1MY55 F1N7X6 G3MWI1 G3X757 P11181 P79132 Q08E52 Q0II80 Q0VBZ0 Q17QZ0 Q3SWX4 Q3SZC4 Q3T0D8 Q3T0Q2 Q3ZCM0 Q8SPJ1 Q95JC7	ARHGDIA ARHGDIB ARHGDIG ASCT2 BRWD2 CAV1 CSK DBT ERP27 FAM91A1 GBAS JUP LAMTOR1 LCK MTR NIPSNAP2 NSFL1C OSBPL11 PAK1 PAK2 PAK4 PAK5 PAK6 RALGAPA1 RHOH ROCK1 ROCK2 SLC1A5 SLC4A7 STOM TFRC TMEM59 VANGL1 VCP WDR11 ZAP70
Fc epsilon receptor (FCERI) signaling	FCER1A protein High affinity immunoglobulin epsilon receptor subunit gamma Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Linker for activation of T cells Membrane spanning 4-domains A2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LKV0 A0A3Q1MHG9 A6QQQ4 E1BNU1 F1MZ60 F1N261 G3N342 Q9BDR7	FCER1A FCER1G LAT LYN MS4A2 SYK
SUMOylation of intracellular receptors	Androgen receptor Estrogen receptor Glucocorticoid receptor Histone deacetylase Mineralocorticoid receptor NR1I2 protein Nuclear receptor subfamily 1 group H member 4 Nuclear receptor subfamily 5 group A member 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta PIAS3 protein PIAS4 protein Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT 1 Protein inhibitor of activated STAT 2 Retinoic acid receptor RXR Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Small ubiquitin-related modifier Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A3Q1LPE8 A0A3Q1LUL4 A0A3Q1M2W5 A0A3Q1M5G9 A0A3Q1ML58 A0A3Q1N5N2 A0A3Q1N8R7 A2VDU4 A4FV15 A6QQU9 F1MN19 F1MTT1 F1MWQ3 F1MX52 F1MYR0 F1N2B6 F1N712 G3MZL6 G3X7C1 G5E5J5 P49884 P61955 Q04752 Q17QV3 Q5BIS6 Q5E9B6 Q5EA13	AD4BP AR ESR ESR1 FTZF1 HDAC4 LOC101906855 LXRA LXRB NR1H2 NR1H3 NR1H4 NR1I2 NR3A1 NR3C1 NR3C2 NR5A1 NR5A2 PGR PIAS1 PIAS2 PIAS3 PIAS4 PPARA RARA RXRA SMT3B SUMO2 SUMO3 THRA THRB VDR
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C Rho/Rac guanine nucleotide exchange factor 18 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M590 A0A3Q1MSP9 A0A3Q1N449 E1B9G8 F1MLS5 F1MYN2 F6RHP0 G3MZV8 O46680 P0CG53 P0CH28 P61585 P62992 P63048 Q9XT56	ARHA ARHGEF18 CGN F11R JAM1 PARD3 PARD6A PRKCZ RHO12 RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Hedgehog 'on' state	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division cycle 73 Cullin 3 DAZ interacting zinc finger protein 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase EvC ciliary complex subunit 1 EvC ciliary complex subunit 2 G protein-coupled receptor 161 GLI family zinc finger 1 GLI family zinc finger 2 GLI family zinc finger 3 Kinesin family member 7 Patched 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta Proteasome subunit beta Protein numb homolog Protein smoothened SUFU negative regulator of hedgehog signaling Serine/threonine-protein kinase ULK3 Speckle type BTB/POZ protein like Speckle-type POZ protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LJ39 A0A3Q1LM07 A0A3Q1M267 A0A3Q1MDV1 A0A3Q1MSE5 A1L5A6 A6H727 A7MBA2 E1B8G1 E1BE57 E1BES3 E1BIN5 E1BPQ8 F1MBI1 F1MCY1 F1MGQ5 F1MLS5 F1MLV1 F1MQQ1 F1MWE0 F1MXE4 F1MYH8 F1N215 F1N332 G3N1D5 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q0VCW1 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2YDE4 Q2YDN1 Q32KL2 Q3MHN0 Q3T030 Q3T0X5 Q3T0Y5 Q3T108 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9K0	ADRM1 CDC73 CUL3 DZIP1 EVC EVC2 GLI1 GLI2 GLI3 GPR161 ITCH KIF7 NUMB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTCH1 RPS27A SMO SMURF1 SMURF2 SPOP SPOPL SUFU SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ULK3
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Cholinergic receptor nicotinic alpha 6 subunit Cholinergic receptor nicotinic alpha 9 subunit Cholinergic receptor nicotinic beta 2 subunit Cholinergic receptor nicotinic beta 3 subunit Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit beta-4	A0A3Q1MJN8 A6QPI7 E1BHK0 F1MC93 F1MDD1 F1MF30 F1MQ06 F1MYI7 F1N4T3 P02709 Q8SPU7	CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB2 CHRNB3 CHRNB4
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 DERPC proline and glycine rich nuclear protein Hyaluronan synthase 2 hyaluronan synthase	A0A3Q1LP80 E1BKX1 F1MY60 F1MZD4 F1N1R2	ABCC5 CEMIP DERPC HAS1 HAS2	G35674CY
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LN00 A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1B7I9 E1B8P9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1N339 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P0CG53 P0CH28 P46196 P62992 P63048 Q3T0F9	AFGF CBL ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 FRS2 Fgf4 GRB2 HBGF-1 MAPK1 MAPK3 PRKM1 PTPN11 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Nuclear signaling by ERBB4	Estrogen receptor Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Receptor protein-tyrosine kinase Signal transducer and activator of transcription 5A Tyrosine-protein kinase WW domain-containing oxidoreductase Yes1 associated transcriptional regulator	A0A3Q1LNM1 A0A3Q1LVN4 A0A3Q1MBH7 A0A3Q1MDC6 A0A3Q1MKB4 E1BIM8 F1MK73 P49884 Q5G235 Q95115 Q9XT96 Q9XT97	APH1A APH1B ERBB4 ESR ESR1 MGF NCSTN NR3A1 PEN2 PSEN1 PSEN2 PSENEN SRC STAT5A WWOX YAP1
IL-6-type cytokine receptor ligand interactions	Cardiotrophin 1 Cardiotrophin like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Interleukin 6 cytokine family signal transducer LIF receptor subunit alpha Leukemia inhibitory factor Oncostatin M Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	E1BAT3 E1BCP6 E1BD36 E1BD91 E1BFH9 F1MCX4 F1MLR4 F1N0D6 F1N366 G3MXT9 Q27956	CLCF1 CNTF CNTFR CTF1 IL6ST JAK1 JAK2 LIF LIFR OSM TYK2

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