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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 19285508 | |
| Norovirus | Unknown | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 18599458 | |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Escherichia coli | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Not Binding | 12704182 | ||
| Escherichia coli | SafS | α-sialyl-2-3-β-galactose | Disaccharides | Binding | 12640357 | ||
| Clostridium botulinum | Neurotoxin (type B) | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Clostridium botulinum | Unknown | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Paracoccidioides brasiliensis | Paracoccin | Laminin | Glycoproteins | Binding | 16476564 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus gordonii | CshB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Escherichia coli | FimH | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | FimH | Laminin | Glycoproteins | Binding | 12010488 | ||
| Streptococcus gordonii | CshaB (Antigen I/II) | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 10341176 | ||
| Klebsiella pneumoniae | MrkD-pili | Collagen (type V) | Glycoproteins | Binding | 12640357 | ||
| Escherichia coli | Type 1-pili | Tamm-Horsfall protein (THP) | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Fibronectin | Glycoproteins | Binding | 12010488 | ||
| Escherichia coli | Type 1-pili | Laminin | Glycoproteins | Binding | 12010488 | ||
| Anaplasma phagocytophilum | "P-selectin mimic, MSP2" | Fucosylated PSGL-1 (P-selectin glycoprotein ligand-1) | Glycoproteins | Binding | 16299269 | ||
| Borrelia burgdorferi | BBK32 | Fibronectin | Glycoproteins | Binding | 18833295 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | C3 and complement factor H | Glycoproteins | Binding | 12640357 |
