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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 16088272 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid(2-O-methyl-α-Neu5Gc (Neu5Gc2Me)) | Monosaccharides | Binding | 17306299 | ||
| Rotavirus | VP8 (galectin) | Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me)) | Monosaccharides | Binding | 17306299 | ||
| Borrelia burgdorferi | "OspA, OspB, OspC" | Gangliosides | Sialoglycosphingolipids | Binding | 16299269 | ||
| Rotavirus | TLP (Triple-layered virus particles) | Gangliosides | Sialoglycosphingolipids | Binding | 10659372 | ||
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Acid glycosphingolipids | Acidic Glycosphingolipids | Not Binding | 12704182 | ||
| Streptococcus pneumoniae | PsaA (Lary family) | N-acetylhexosamine-galactose | Disaccharides | Binding | 12640357 | ||
| Helicobacter pylori | Unknown | Epithelial type of glycolipid containing 2-hydroxy fatty acid | Glycolipids | Binding | 8574698 | ||
| Helicobacter pylori | Unknown | Monohexyl ceramides (MHCer) | Glycolipids | Binding | 16088272 | ||
| Escherichia coli | (class III) | GL-III glycolipid | Glycolipids | Not Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-III glycolipid | Glycolipids | Binding | 7721812 | ||
| Escherichia coli | (class I/II) | GL-IV glycolipid | Glycolipids | Binding | 7721812 | ||
| Helicobacter pylori | Unknown | Mucin | Glycoproteins | Binding | 16088272 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | C3 and complement factor H | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Staphylococcus aureus | FnbB | Fibronectin | Glycoproteins | Binding | 10341176 | ||
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Fetuin | Glycoproteins | Binding | 1729677 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Staphylococcus aureus | FnbA | Fibronectin | Glycoproteins | Binding | 12640357 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 89,000 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Fusobacterium nucleatum | Lectin-like proteins (adhesin) | Mr 36,900 PRG (Proline-Rich Glycoprotein) | Glycoproteins | Binding | 1894623 | ||
| Streptococcus gordonii | CshA | Fibronectin | Glycoproteins | Binding | 10341176 |
