GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **557** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Prostaglandin E synthase 3 Serine/threonine-protein phosphatase peptidylprolyl isomerase peptidylprolyl isomerase	A0A452DIU3 F1MU79 F1N719 G3MXV0 P49884 Q76LV1 Q76LV2 Q9XSB5	ESR ESR1 ESR2 FKBP4 FKBP5 HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB NR3A1 NR3A2 PPP5C PTGES3	Bos taurus (cattle)
CD209 (DC-SIGN) signaling	NF-kappaB transcription factor p65 subunit Nuclear factor NF-kappa-B p105 subunit RELB proto-onco, NF-kB subunit Ribosomal protein S6 kinase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase histone acetyltransferase histone acetyltransferase	A0A452DJE2 A1XG22 E1B8D6 E1BN61 F1MBB0 F1MD32 F1MKW9 P00517	CREBBP EP300 NFKB1 PRKACA PRKACB RELA RELB RPS6KA5	Bos taurus (cattle)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	A0A493UA87 Q58D31	AKR1B1 SORD	Bos taurus (cattle)	G58161NS
Reuptake of GABA	Sodium- and chloride-dependent GABA transporter 2 Transporter Transporter	A0JND1 A5PJX7 E1BPI1	SLC6A1 SLC6A11 SLC6A13	Bos taurus (cattle)
Digestion of dietary lipid	Carboxylic ester hydrolase Colipase Lipase Pancreatic lipase-related protein 2 Triacylglycerol lipase Triacylglycerol lipase	A0JNQ7 A5PK46 E1BJQ9 F1MC21 F1MES3 Q58DG4	CEL CLPS LIPF PNLIP PNLIPRP2 PNLIPRP3	Bos taurus (cattle)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK protein Transcription factor AP-2-alpha	A1A4R9 A5PJQ1	DEK TFAP2A	Bos taurus (cattle)
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glutathione S-transferase omega Glutathione-dependent dehydroascorbate reductase NADH-cytochrome b5 reductase 3 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 23 member 1 Solute carrier family 23 member 2	A2VDL2 E1BED9 E1BI45 E1BJ08 E1BP61 P00171 P07514 P27674	CYB5 CYB5A CYB5R3 DIA1 GLUT1 GSTO2 SLC23A1 SLC23A2 SLC2A1 SLC2A3	Bos taurus (cattle)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A2VE07 Q2KIA5 Q2LGB8 Q5E9F1	BCAP31 CASP8 DNM1L STK24	Bos taurus (cattle)
P2Y receptors	G protein-coupled receptor 17 LPAR4 protein Lysophosphatidic acid receptor 6 P2Y purinoceptor 14 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 4 P2Y receptor family member 10 Purinergic receptor P2Y, G-protein coupled, 12 Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6	A2VEA2 A4IFV1 A6QL49 F1MDI7 F1MDW9 F1MTB2 F1MU50 G3X6Q0 P48042 Q0IIL0 Q3SX17	GPR17 LPAR4 LPAR6 P2RY1 P2RY10 P2RY11 P2RY12 P2RY14 P2RY2 P2RY4 P2RY5 P2RY6	Bos taurus (cattle)
Leukotriene receptors	CYSLTR2 protein Cysteinyl leukotriene receptor 1 G protein-coupled receptor 17 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2	A2VEA2 A5PKG3 A7MBH4 F1MRY8 Q3T181	CYSLTR1 CYSLTR2 GPR17 LTB4R LTB4R2	Bos taurus (cattle)
ATF6B (ATF6-beta) activates chaperones	ATF6B protein MBTPS1 protein Membrane-bound transcription factor site-2 protease	A4FUY2 Q08E55 Q0III2	ATF6B MBTPS1 MBTPS2	Bos taurus (cattle)
Transport of RCbl within the body	ATP binding cassette subfamily D member 4 CD320 antigen LDL receptor related protein 2 LDLRAP1 protein Lysosomal cobalamin transport escort protein LMBD1 Multidrug resistance-associated protein 1 Transcobalamin 1 Transcobalamin-2	A4IFV0 A6QNY1 E1BCU6 F1N364 F1N3B4 F1N6H1 Q8HXQ5 Q9XSC9	ABCC1 ABCD4 CD320 LDLRAP1 LMBRD1 LRP2 MRP1 TCN1 TCN2	Bos taurus (cattle)
Zinc influx into cells by the SLC39 gene family	Metal cation symporter ZIP14 Solute carrier family 39 member 2 Solute carrier family 39 member 8 Zinc transporter SLC39A7 Zinc transporter ZIP1 Zinc transporter ZIP4 Zinc transporter ZIP6	A5D7L5 E1BEU4 E1BQ28 G3MYG6 Q0P5C9 Q1KZG0 Q3SYU3	SLC39A1 SLC39A14 SLC39A2 SLC39A4 SLC39A6 SLC39A7 SLC39A8 ZIP1 ZIP4	Bos taurus (cattle)
Tie2 Signaling	Angiopoietin-1 receptor Angiopoietin-1 Angiopoietin-2 Angiopoietin-like protein 4 Docking protein 2 GTPase NRas Growth factor receptor bound protein 14 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A5D7R9 A7MBB8 B2Z4B2 E1BMX0 F1MBA2 F1MYM3 F1N339 F1N7C3 O18920 O77802 P23726 P23727 P32871 Q06807 Q0IIE2 Q1RMW5 Q3T0F9	ANG1 ANG2 ANGPT1 ANGPT2 ANGPT4 ANGPTL4 DOK2 GRB14 GRB2 GRB7 KRAS NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PTPN11 SHC1 SOS1 TEK TIE-2 TIE2	Bos taurus (cattle)
Sensory perception of salty taste	Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Sodium channel epithelial 1 subunit delta	A5D7U4 F1MJW3 F1MY57 P55270	SCNN1A SCNN1B SCNN1D SCNN1G	Bos taurus (cattle)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A5PJB2 F1MV64	INS INSR	Bos taurus (cattle)
Androgen biosynthesis	17beta-estradiol 17-dehydrogenase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenol reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	A5PJS2 A6H7H3 E1BCQ0 E1BJY8 F6RUH3 P01190 P01217 P04651 P05185 P14893	CGA CYP17 CYP17A1 HSD17B12 HSD17B3 HSD3B LHB LOC789567 POMC SRD5A1 SRD5A2 SRD5A3	Bos taurus (cattle)
p53-Dependent G1 DNA Damage Response	CDKN1A protein Cyclin E1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E2	A5PKM2 A6QLS3 E1B9U2 F1MVR8 G8JKW1 Q5E9K7 Q5E9Y0	CCNA1 CCNA2 CCNE1 CCNE2 CDK2 CDKN1A CDKN1B CDKN2	Bos taurus (cattle)
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen IZUMO family member 2 IZUMO family member 4 Izumo sperm-egg fusion protein 3 Izumo sperm-oocyte fusion 1	A6QL94 E1BC82 E1BDA8 F1MYA6 G5E5C6 P30932	ACR CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4	Bos taurus (cattle)
Chromatin modifying enzymes	Bromodomain and WD repeat domain containing 1 Histone H3.1 Histone H3.2 Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Transcription activator BRG1	A6QLC1 A7Z019 E1BCN3 E1BD46 F1MTQ0 F1N048 F1N404 P68432 P84227	BAF190A BRG1 BRWD1 PADI1 PADI2 PADI3 PADI4 PADI6 SMARCA4 SNF2B SNF2L4	Bos taurus (cattle)
Creatine metabolism	Creatine kinase B-type Creatine kinase M-type Creatine kinase S-type, mitochondrial Creatine kinase U-type, mitochondrial Glycine amidinotransferase, mitochondrial Guanidinoacetate N-methyltransferase Sodium- and chloride-dependent creatine transporter 1 Transporter Transporter	A6QLU4 E1BPI1 F1MJT6 O18875 Q2HJ74 Q2TBQ3 Q5EA61 Q9TTK8 Q9XSC6	CKB CKM CKMT1 CKMT2 GAMT GATM SLC6A11 SLC6A7 SLC6A8	Bos taurus (cattle)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 NAD(+) hydrolase SARM1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A6QNL0 C4T7Z1 E1BIR9 Q2LGB7 Q6WCD5	CD14 LY96 MD-2 SARM1 TICAM2 TLR4 TRAM	Bos taurus (cattle)
Scavenging by Class A Receptors	Apolipoprotein B Collectin-11 Collectin-12 MBL associated serine protease 1	A6QP79 E1BNR0 F1MVS9 Q17QH6	APOB CLP1 COLEC11 COLEC12 MASP1	Bos taurus (cattle)	G27025MB G70323CJ G82576YO
Activation of Matrix Metalloproteinases	72 kDa type IV collagenase Cathepsin K Collagen type XVIII alpha 1 chain Collagenase 3 Elastase, neutrophil expressed Glandular kallikrein Matrix metallopeptidase 11 Matrix metallopeptidase 15 Matrix metallopeptidase 16 Matrix metallopeptidase 17 Matrix metallopeptidase 24 Matrix metallopeptidase 25 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Metalloproteinase inhibitor 2 NTR domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Plasma kallikrein Plasminogen Procathepsin L Stromelysin-1 TPSB1 protein chymotrypsin furin interstitial collagenase trypsin	A6QPI9 A7YWU6 A7YWU9 B0JYR0 E1B726 E1B8U1 E1BAD2 E1BH36 E1BIP7 F1MHG1 F1MKH8 F1MMD4 F1MT97 F1MTK6 F1MTX6 F1MU56 F1MW26 F1MY12 F1N1E3 F1N1F5 F1N430 F1N6W9 F1N797 G3MWP1 G3N0J0 P25975 P52176 Q2KJ63 Q5E968 Q6H320	COL18A1 CTRB1 CTSK CTSL CTSL1 ELANE FURIN KLK1 KLKB1 KLNA1 LOC100139881 LOC112441463 LOC112442231 LOC509956 LOC540321 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 MMP2 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 PLG PRSS2 TIMP2 TPSB1	Bos taurus (cattle)
Events associated with phagocytolytic activity of PMN cells	Lactoperoxidase MPO protein	A6QPT4 P80025	LPO MPO	Bos taurus (cattle)

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