GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase protein-serine/threonine phosphatase protein-serine/threonine phosphatase	A0A3Q1MLC5 A6QLS1 E1B8P9 E1BAA9 F1MEZ2 F1MI99 F1MM08 F1MQM7 P46196 Q0IID7 Q0VCY8 Q2KJ36	DUSP1 DUSP10 DUSP16 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK2 MAPK1 MAPK3 PEA15 PRKM1	Bos taurus (cattle)
Glycosphingolipid catabolism	ARSB protein ARSE protein Acid ceramidase Alpha-galactosidase Arylsulfatase A Arylsulfatase G Arylsulfatase K Arylsulfatase family member H Arylsulfatase family member I Beta-galactosidase Beta-galactosidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase Carboxypeptidase Cation-dependent mannose-6-phosphate receptor Ectonucleotide pyrophosphatase/phosphodiesterase 7 Formylglycine-generating enzyme Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 Glucosylceramidase Inactive C-alpha-formylglycine-generating enzyme 2 Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase 4 Sphingomyelin phosphodiesterase Steroid sulfatase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase	A0A140T8C6 A0A3Q1LZ44 A0A3Q1NDQ7 A0A452DJ87 A5D7J7 A6BMK7 A6QLZ3 E1B725 E1B7K0 E1BCP9 E1BFH4 E1BI28 E1BIN3 E1BJU5 E1BMN0 F1MBU2 F1MND2 F1MNT6 F1MRJ3 F1MY73 F1N1D5 F1N1R7 F1N665 G3N2T7 G5E5Q1 H7BWW2 P11456 Q08DD1 Q0P5L5 Q0V8R6 Q0VD19 Q148F3 Q17QB3 Q58CP2	ARSA ARSB ARSE ARSG ARSH ARSI ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA1 GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GM2A HEXA HEXB M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD3 SMPD4 STS SUMF1 SUMF2	Bos taurus (cattle)	G09546QO G27025MB G58161NS
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand CD40 ligand LTBR protein Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 14 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5	A0A3Q1LHY0 A0A3Q1MKD6 A0A452DIT3 A6QQ46 B0LKN7 E1B9D9 E1BBH2 E1BIP0 E1BK50 E1BL08 F1MJD0 F1MTC1 F1MX43 F1N0K4 G3X822 Q06600 Q28203 Q3SYW8	BIRC2 BIRC3 CD40 CD40LG LTA LTB LTBR MAP3K14 NCR3 TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNLG1D TNLG7A TRAF2 TRAF3	Bos taurus (cattle)
Regulation of NF-kappa B signaling	Caspase 8 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor of nuclear factor kappa-B kinase-interacting protein Leucine-rich repeat-containing protein 14 NEDD4-binding protein 1 NF-kappa-B essential modulator NLR family CARD domain containing 5 NLR family member X1 Polyubiquitin-B Polyubiquitin-C TNF receptor-associated factor 6 TNF receptor-associated factor Ubiquitin carboxyl-terminal hydrolase 14 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1ME40 A2VE53 A5PJJ5 E1B9D9 E1B9F2 F1MUU5 P0CG53 P0CH28 P62992 P63048 Q0IIF7 Q2LGB8 Q3ZCC3 Q95KU9 Q95KV0 Q95KV1	CASP8 CHUK IKBIP IKBKB IKBKG IKIP IKKA LRRC14 N4BP1 NEMO NLRC5 NLRX1 RPS27A TRAF2 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP14	Bos taurus (cattle)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 6 Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 7	A0A3Q1LTG6 A0A3Q1M4W2 A0A3Q1N7P8 E1B742 E1BIH1 E1BIP1 E1BKE7 F1MUF3 F1MVZ6 F1MX21 F1N7A9 Q5E9U1 Q9MYW0	ITPR1 ITPR2 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRP6 TRPC3 TRPC6 TRPC7	Bos taurus (cattle)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C Rho/Rac guanine nucleotide exchange factor 18 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M590 A0A3Q1MSP9 A0A3Q1N449 E1B9G8 F1MLS5 F1MYN2 F6RHP0 G3MZV8 O46680 P0CG53 P0CH28 P61585 P62992 P63048 Q9XT56	ARHA ARHGEF18 CGN F11R JAM1 PARD3 PARD6A PRKCZ RHO12 RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 4 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(t) subunit alpha-3 Leptin Pro-glucagon	A0A3Q1NGS8 E1B8Q3 E1BKC0 G5E5H9 G8BLB4 P01272 P0C7Q4 P62871 P81425 Q863C3	CD26 DPP4 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GPR120 GRP LEP ob	Bos taurus (cattle)	G58161NS
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Adenosine 5'-monophosphoramidase HINT1 Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Eukaryotic translation elongation factor 1 epsilon 1 Exportin 1 Glutamine--tRNA ligase Glutamyl-prolyl-tRNA synthetase 1 Glycogen synthase kinase-3 beta Kit ligand Lysine--tRNA ligase Mast/stem cell growth factor receptor Melanocyte inducing transcription factor Methionine--tRNA ligase, cytoplasmic Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Protein Wnt Ribosomal protein S6 kinase histone acetyltransferase isoleucine--tRNA ligase leucine--tRNA ligase	A0A3Q1LLF2 A0A3Q1LTW2 A0A3Q1LXT8 A0A3Q1MKP6 A0A3Q1MKR2 A0A3Q1MLN6 A0A3Q1MQJ9 A0A3Q1NC15 A0A3S5ZPT9 A0A452DHX3 A0A452DIE9 A7MBC5 A7YW98 E1B8P9 E1BE98 F1MD32 F1MIC3 F1MMK8 P46196 Q0II26 Q28132 Q3MHH4 Q3SZ15	AIMP2 CREBBP DARS1 EEF1E1 EPRS1 ERK2 GSK3B HINT1 IARS IARS1 JTV1 KARS1 KIT KITLG LARS1 MAPK1 MAPK3 MARS1 MITF PRKM1 QARS QARS1 RARS RARS1 RPS6KA1 SCF WNT3A XPO1	Bos taurus (cattle)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Amphiregulin Betacellulin CD19 molecule CD80 molecule CD86 molecule Epiregulin Epithelial mitogen Estrogen receptor beta Estrogen receptor FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene vav Ras homolog family member G Ras-related C3 botulinum toxin substrate 2 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M535 A0A3Q1M7J4 A0A3Q1M864 A0A3Q1MCW9 A0A3Q1ME99 A0A3Q1MGW7 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MLL9 A0A3Q1MPT9 A0A3Q1N3Z8 A0A3Q1NAV6 A0A3Q1ND77 A0A3S5ZP81 A0A452DHW6 A0A452DHX3 A0JNB0 A0MTF4 A2VE24 A2VE27 A6QLU3 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1BAI2 E1BBE2 E1BDM2 E1BE66 E1BFL8 E1BFP8 E1BGY3 E1BHC1 E1BIM8 E1BIN8 E1BJU2 E1BP37 F1MCQ7 F1MDQ5 F1MEV4 F1MHC6 F1MJE0 F1MN51 F1MPD0 F1MQJ7 F1MRU0 F1MRU1 F1MS28 F1MYE0 F1MYM3 F1MZD6 F1N339 F1N4S9 F1N586 F1N6G8 F2Z4J0 G3MXR4 G3N104 G3XGD3 P03968 P03969 P23726 P23727 P32871 P49884 Q08DN7 Q08DU3 Q1RMI2 Q1RMT8 Q28132 Q2KJ15 Q2LGB3 Q3T0F9 Q3ZCC3 Q3ZCM0 Q58DF9 Q9TU25 Q9XSB5 Z4YHD9	AFGF AREG BTC CD19 CD28 CD80 CD86 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HBGF-1 HGF ICOS IL1RL1 IL33 IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MET MYD88 NR3A1 NR3A2 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTPN11 RAC2 RHOG SCF SRC STRN TGFA TRAF6 TRAT1 VAV1	Bos taurus (cattle)
Chromatin modifying enzymes	Bromodomain and WD repeat domain containing 1 Histone H3.1 Histone H3.2 Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Protein-arginine deiminase Transcription activator BRG1	A6QLC1 A7Z019 E1BCN3 E1BD46 F1MTQ0 F1N048 F1N404 P68432 P84227	BAF190A BRG1 BRWD1 PADI1 PADI2 PADI3 PADI4 PADI6 SMARCA4 SNF2B SNF2L4	Bos taurus (cattle)
Events associated with phagocytolytic activity of PMN cells	Lactoperoxidase MPO protein	A6QPT4 P80025	LPO MPO	Bos taurus (cattle)
Amine ligand-binding receptors	G protein-coupled receptor 143 G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Trace amine associated receptor 2 Trace amine associated receptor 5 Trace amine associated receptor 9 Trace amine-associated receptor 1	A0A3Q1ML96 F1MJF8 F1MTC9 F1MX10 F1N0G5 G3MZW8 G3X880 G5E581	GPR143 LOC511136 LOC516101 TAAR1 TAAR2 TAAR3 TAAR5 TAAR9	Bos taurus (cattle)
Nuclear signaling by ERBB4	Estrogen receptor Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Gamma-secretase subunit PEN-2 Nicastrin Presenilin-1 Presenilin-2 Receptor protein-tyrosine kinase Signal transducer and activator of transcription 5A Tyrosine-protein kinase WW domain-containing oxidoreductase Yes1 associated transcriptional regulator	A0A3Q1LNM1 A0A3Q1LVN4 A0A3Q1MBH7 A0A3Q1MDC6 A0A3Q1MKB4 E1BIM8 F1MK73 P49884 Q5G235 Q95115 Q9XT96 Q9XT97	APH1A APH1B ERBB4 ESR ESR1 MGF NCSTN NR3A1 PEN2 PSEN1 PSEN2 PSENEN SRC STAT5A WWOX YAP1	Bos taurus (cattle)
EPHB-mediated forward signaling	Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Focal adhesion kinase 1 Intersectin 1 RAS p21 protein activator 1 Rho guanine nucleotide exchange factor 28 Rho-associated protein kinase Serine/threonine-protein kinase PAK 1 Syndecan-2 Transforming protein RhoA non-specific serine/threonine protein kinase	A0A3Q1LKT3 A0A3Q1MW77 A0A3Q1N508 A7MB62 E1BKY4 F1MF50 F1N7N8 G3MXC8 P60712 P61157 P61585 P63258 Q08E52 Q148J6 Q1JP79 Q2KJ93 Q3MHR7 Q3T035 Q58CQ2 Q58DD4 Q95107	ACTB ACTG ACTG1 ACTR2 ACTR3 ARHA ARHGEF28 ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CDC42 ITSN1 PAK1 PTK2 RASA1 RHO12 RHOA ROCK1 ROCK2 SDC2 WASL	Bos taurus (cattle)
VEGF binds to VEGFR leading to receptor dimerization	FIGF protein Placenta growth factor Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3 receptor protein-tyrosine kinase	A7MBB6 F1MDD9 F1MHP5 F1MWF1 P15691 Q9XS47 Q9XS49 Q9XS50	FIGF FLT1 FLT4 KDR PGF PLGF VEGF VEGFA VEGFB VEGFC VEGFD VRF	Bos taurus (cattle)
Separation of Sister Chromatids	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 AT-hook containing transcription factor 1 Alpha isoform of regulatory subunit A, protein phosphatase 2 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Aurora kinase B9 domain-containing protein 2 BUB1 mitotic checkpoint serine/threonine kinase B BUB1 protein Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain containing linker protein 1 CENPI protein CENPP protein Cell division cycle 16 Cell division cycle 20 Cell division cycle associated 5 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein E Centromere protein F Centromere protein H Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein Q Centromere protein S Centromere protein T Cohesin subunit SA Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic linker associated protein 1 Cytoplasmic linker associated protein 2 Cytoskeleton associated protein 5 DNA excision repair protein ERCC-6-like DSN1 component of MIS12 kinetochore complex Double-strand-break repair protein rad21 homolog Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain E2 ubiquitin-conjugating enzyme Exportin 1 Histone H3-like centromeric protein A Histone deacetylase 8 Inner centromere protein Integrin subunit beta 3 binding protein Kinesin-like protein Kinetochore associated 1 Kinetochore protein NDC80 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Microtubule-associated protein RP/EB family member 1 Mitotic arrest deficient 1 like 1 Mitotic arrest deficient 2 like 1 Mitotic checkpoint protein BUB3 NDE1 protein NSL1 protein NUF2 component of NDC80 kinetochore complex NUP43 protein Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nuclear pore complex protein Nucleoporin 133 Nucleoporin 160 Nucleoporin 37 Nucleoporin SEH1 PDS5 cohesin associated factor A PDS5 cohesin associated factor B Platelet-activating factor acetylhydrolase IB subunit alpha Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein MIS12 homolog Protein SEC13 homolog Protein Spindly Protein phosphatase 2 scaffold subunit Abeta Protein zwilch homolog RAN binding protein 2 RCC2 protein Ran GTPase activating protein 1 STAG1 cohesin complex component Serine/threonine-protein kinase PLK1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WAPL cohesin release factor ZW10 interacting kinetochore protein ZW10, kinetochore associated, homolog (Drosophila) non-specific serine/threonine protein kinase separase	A0A3Q1LLS4 A0A3Q1LQI2 A0A3Q1LTH6 A0A3Q1M302 A0A3Q1M6A8 A0A3Q1M862 A0A3Q1MAP0 A0A3Q1MAR8 A0A3Q1MDJ2 A0A3Q1MMV9 A0A3Q1MQQ6 A0A3Q1MWV1 A0A3Q1NEK5 A0A3Q1NEU9 A0A452DI44 A0A452DIY4 A1A4R8 A2VDZ0 A3KMW1 A4FV68 A4IFM5 A5D7P3 A5D973 A6H7B3 A6QL85 A6QLS4 A6QLW0 A6QM04 A6QPS5 A6QQ16 A6QQ81 A6QQR4 A7MBA2 A7YWP8 A7YY75 A7Z061 A7Z065 E1B7K5 E1B945 E1BAB6 E1BAK5 E1BBQ0 E1BCV4 E1BD42 E1BD83 E1BDU0 E1BE98 E1BF82 E1BG49 E1BGC3 E1BJ19 E1BK11 E1BKG4 E1BLA0 E1BM34 E1BPM5 E1BQ15 F1MBI1 F1MBQ0 F1MC39 F1MFD5 F1MGX8 F1MLG9 F1MLV1 F1MM55 F1MNP7 F1MQN0 F1MR95 F1MRW5 F1MT24 F1MUQ7 F1MW01 F1MWE0 F1MWP1 F1MWW9 F1MXE4 F1MYH8 F1MZR0 F1N0Y3 F1N1F8 F1N1S8 F1N6Z0 F1N7G8 F1N7G9 F2Z4G9 G3MX31 G3MXW4 G3N1P6 G3N2Y5 G3X6R3 G5E589 G5E613 O97593 P0CG53 P0CH28 P33672 P56701 P61285 P61287 P62194 P62992 P63048 P67774 Q08DN4 Q08DP7 Q08DW5 Q0P594 Q0P5L6 Q17QG2 Q17QP9 Q1JQB2 Q1RML1 Q29RQ3 Q2KHT7 Q2KI42 Q2KII9 Q2KJ25 Q2KJ46 Q2KJE7 Q2T9N4 Q2TA10 Q2TA25 Q2TBH1 Q2TBR7 Q2YDE4 Q32KL2 Q32PA5 Q3MHN0 Q3MHR3 Q3SWX9 Q3SX30 Q3SZ19 Q3SZ31 Q3SZC2 Q3SZT7 Q3T030 Q3T0L1 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBD9 Q3ZBG0 Q3ZBK3 Q3ZBK8 Q3ZC98 Q3ZCC9 Q3ZCF6 Q3ZCK9 Q58DR0 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q5EA18 Q5EA49 Q6J1J1	AHCTF1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 APITD1 AURKB B9D2 BIRC5 BUB1 BUB1B BUB3 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA5 CDCA8 CENPC CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPO CENPP CENPQ CENPS CENPT CKAP5 CLASP1 CLASP2 CLIP1 DNCL1 DSN1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ERCC6L ESPL1 FAAP16 HDAC8 INCENP ITGB3BP KIF2B KNL1 KNTC1 LIS1 MAD1L1 MAD2L1 MAPRE1 MCM21R MHF1 MIS12 NDC80 NDE1 NDEL1 NSL1 NUDC NUF2 NUP107 NUP133 NUP160 NUP37 NUP43 NUP85 NUP98 PAFAH1B1 PDS5A PDS5B PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5D PPP2R5E PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RAD21 RANBP2 RANGAP1 RCC2 RPS27 RPS27A SCC1 SEC13 SEC13L1 SEH1L SGO1 SGO2 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SPBC25 SPC24 SPC25 SPDL1 STAG1 STAG2 SUG1 TAOK1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S WAPL XPO1 ZW10 ZWILCH ZWINT	Bos taurus (cattle)
Androgen biosynthesis	17beta-estradiol 17-dehydrogenase 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-oxo-5-alpha-steroid 4-dehydrogenase 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glycoprotein hormones alpha chain Lutropin subunit beta Polyprenol reductase Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Very-long-chain 3-oxoacyl-CoA reductase	A5PJS2 A6H7H3 E1BCQ0 E1BJY8 F6RUH3 P01190 P01217 P04651 P05185 P14893	CGA CYP17 CYP17A1 HSD17B12 HSD17B3 HSD3B LHB LOC789567 POMC SRD5A1 SRD5A2 SRD5A3	Bos taurus (cattle)
FCERI mediated NF-kB activation	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell CLL/lymphoma 10 Caspase recruitment domain family member 11 Cell division cycle 34, ubiqiutin conjugating enzyme Cullin 1 F-box and WD repeat domain containing 11 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein kinase C S-phase kinase-associated protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor 6 Tyrosine-protein kinase Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LKV0 A0A3Q1LT51 A0A3Q1M118 A0A3Q1M7T8 A0A3S5ZPB2 A0A452DI44 A0A452DIY4 A1XG22 A2VDU3 A7MBA2 E1B7Z0 E1BD83 E1BMG4 F1MBI1 F1MBS7 F1MKW9 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N261 F1N4D3 F1N6Z0 G3N342 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QJ6 Q17QP9 Q1RMX2 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA10 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCC3 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	BCL10 CARD11 CDC34 CHUK CUL1 FBXW11 IKBKB IKBKG IKKA LYN MALT1 MAP3K7 NEMO NFKB1 NFKBIA PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RELA RPS27A SKP1 SKP1A SUG1 TAB1 TAB2 TAB3 TRAF6 TRAP2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 bIkBa	Bos taurus (cattle)
Detoxification of Reactive Oxygen Species	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Glutathione S-transferase Glutathione S-transferase Glutathione peroxidase 1 Glutathione peroxidase 3 Glutathione peroxidase 7 Glutathione peroxidase Glutathione peroxidase Glutathione reductase NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Superoxide dismutase copper chaperone Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	A0A3Q1LMV5 A0A3Q1M7E3 A0A3Q1MKI4 A0A3Q1MTW8 A0A452DHY1 A0A452DHY4 A5PJN2 A6QLY2 E1BE86 E1BHL1 E1BKZ1 F1MCF5 F1MNQ4 F1MQX5 F6PZE4 F6Q9Q9 F6R4N7 O46521 O46522 O62768 O77834 O97680 P00432 P00435 P00442 P35705 P37141 P62894 Q29RJ1 Q2NL01 Q5E947 Q95108 Q9BGI1 Q9BGI3 Q9N2I8	AOP1 AOP2 CAT CCS CYBA CYBB CYC CYCS ERO1A ERO1L GPX GPX1 GPX3 GPX5 GPX7 GPX8 GSR GSTP1 NCF1 NCF2 NCF4 NOX4 NOX5 NUDT2 P4HB PHGPX PRDX1 PRDX2 PRDX3 PRDX5 PRDX6 SOD1 SOD2 SOD3 TRXR2 TXN TXN2 TXNRD1 TXNRD2	Bos taurus (cattle)
G alpha (12/13) signalling events	A-kinase anchoring protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor FGD1 family, member 3 FGD1 protein FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 4 G protein subunit alpha 12 G protein subunit alpha 13 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Intersectin 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G5 Plexin B1 Proto-oncogene vav Rac/Cdc42 guanine nucleotide exchange factor 6 Ras protein specific guanine nucleotide releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rho/Rac guanine nucleotide exchange factor 18 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 2 Thromboxane A2 receptor Transforming protein RhoA Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A3Q1LFQ5 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUW4 A0A3Q1LXW7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA22 A0A3Q1MA88 A0A3Q1MA97 A0A3Q1MAT2 A0A3Q1MD11 A0A3Q1MIT6 A0A3Q1MN47 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N5H1 A0A3Q1N6F4 A0A3Q1NGS8 A0A3S5ZPL0 A4IFL6 A5D7I5 A5PKD6 A6QNS3 E1B7F6 E1B7M1 E1B7W0 E1B8Q3 E1B9G8 E1BBD2 E1BDY4 E1BH05 E1BIL1 E1BIM5 E1BKY4 E1BP14 E1BQ24 F1MBM9 F1MF50 F1MGA6 F1MJ96 F1MLS2 F1MM93 F1MPJ6 F1MSU8 F1MYW8 F1N0Q1 F1N1J9 F1N1Q7 F1N2G5 F1N7C3 G5E6P3 P02698 P11017 P30671 P50154 P61585 P62871 P63212 P63214 P63217 Q08DA6 Q08DN7 Q0P5E3 Q1RMJ6 Q28024 Q3SZ98 Q3ZC95 Q58CS5 Q5E9F0 Q95125	ABR ADRA1A ADRA1B ADRA1D AKAP13 ARHA ARHC ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BTK FGD1 FGD2 FGD3 FGD4 GNA12 GNA13 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 ITSN1 L2HGDH MCF2L NET1 NGEF PLEKHG2 PLEKHG5 PLXNB1 PREX1 RASGRF2 RHO12 RHOA RHOC ROCK1 ROCK2 SOS1 SOS2 TBXA2R TIAM2 TRIO VAV1 VAV2 VAV3	Bos taurus (cattle)
Glycerophospholipid catabolism	Glycerophosphocholine choline phosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	E1BMJ5 F1N5C8 Q3T0T0	ENPP6 GDE1 MIR16 PNPLA6	Bos taurus (cattle)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	F1MGG8 F1MJE0 F1MYE0 G1K218 P07455 P07456	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Bos taurus (cattle)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 FAD synthase Riboflavin transporter Solute carrier family 52, riboflavin transporter, member 3 Tartrate-resistant acid phosphatase type 5 riboflavin kinase	A0A3Q1MPJ2 A0A3Q1N6I5 E1B8A0 F1MNS5 F6R223 Q5E9R1	ACP5 ENPP1 FLAD1 RFK RFT2 SLC52A2 SLC52A3	Bos taurus (cattle)
Rhesus glycoproteins mediate ammonium transport.	Ammonium transporter Rh type A Ammonium transporter Rh type B Ammonium transporter Rh type C	A0A3Q1M0T1 F1MKX8 Q95M77	RHAG RHBG RHCG	Bos taurus (cattle)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 A7MBH9 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P0C7Q4 P19754 P63097 Q3ZCA7	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAI1 GNAI2 GNAI3 GNAL GNAT3	Bos taurus (cattle)

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