GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **557** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Prednisone ADME	11-beta-hydroxysteroid dehydrogenase type 2 AKR1C4 protein ATP binding cassette subfamily B member 1 Albumin Corticosteroid-binding globulin Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostaglandin F synthase 2 UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A140T897 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1LZ03 A0A3Q1M423 A0A3Q1MB23 A0A3Q1MIN6 E1BBB3 E1BF81 E1BG58 E1BJU8 E1BP71 F1MFF6 F1MNC0 F1MT58 F1N3U0 G3X6I4 M0QW04 M0QW14 M0QW25 P52897 P52898 Q29RV2 Q3T047 Q3ZBG2	ABCB1 AKR1C4 ALB CBG CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 HSD11B2 LOC100138004 LOC100138908 LOC100296421 LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 SERPINA6 UGT1A6 UGT2B10	Bos taurus (cattle)
Post-translational protein phosphorylation	APOL3 protein APOL3 protein Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antiproteinase Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid-beta A4 protein Anoctamin Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3-like Apolipoprotein L3 Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Complement component 4A Cystatin-C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20A golgi associated secretory pathway pseudokinase FAM20C golgi associated secretory pathway kinase Fibrillin-1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein ITIH2 protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Interleukin-6 Kinectin 1 Kininogen 1 LOC510193 protein Latent transforming growth factor beta binding protein 1 MBTPS1 protein MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Menin Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 NTR domain-containing protein Nucleobindin-1 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein shisa-5 Reticulocalbin 1 SERPINA10 protein SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family D member 1 Stanniocalcin-2 Syndecan-2 Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein ferroxidase von Willebrand factor A domain-containing protein 1	A0A140T881 A0A140T885 A0A140T897 A0A140T8C8 A0A140T8D3 A0A3Q1LIS3 A0A3Q1LMK4 A0A3Q1LRR3 A0A3Q1LUG2 A0A3Q1LVS2 A0A3Q1LZU0 A0A3Q1M2R2 A0A3Q1M616 A0A3Q1MB94 A0A3Q1MEX5 A0A3Q1MJT5 A0A3Q1N3Y2 A0A3Q1N5X6 A0A3Q1NAS1 A0A3Q1NC75 A0A3Q1NIX0 A0A452DHZ5 A0A452DII7 A0A452DJ03 A0A5H1ZRH6 A4FUZ9 A5D7R6 A5PJ69 A6QLI2 A6QP86 A6QPR4 A6QQR3 E1B8P3 E1BF93 E1BG25 E1BG36 E1BH06 E1BHJ7 E1BJF8 E1BJU2 E1BLA8 E1BNR0 F1MAZ4 F1MD94 F1ME65 F1MEA1 F1MI67 F1MJM1 F1MJW4 F1MKR5 F1MPP2 F1MRZ6 F1MVK1 F1MXX6 F1MY12 F1MZ40 F1N036 F1N076 F1N0I3 F1N444 F1N5H2 F2Z4E0 F6Q9Q9 F6QH94 F6QND5 F6QSG5 F6R4P6 F6RJ01 G3N2L2 G3N2W6 G3N348 G3X6N3 G3X724 G5E5A9 G5E5T0 O77836 P01035 P01211 P02817 P11116 P12763 P15497 P20616 P20959 P24591 P26892 P34955 P81282 P81644 P98133 Q05716 Q05717 Q08E55 Q0P5I0 Q10741 Q1LZE9 Q27967 Q28034 Q2KJH1 Q2UVX4 Q3SZ57 Q3T0A9 Q3ZBZ6 Q58D84 Q58DD4 Q6PX77 Q95M18	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APOA1 APOA2 APOA5 APOB APOE APOL3 APP BMP15 BMP4 BPIFB2 C3 C4A CALU CCN1 CDH2 CHGB CHGC CHRDL1 CKAP4 CP CSF1 CSPG2 CST3 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FETUA FGA FGF23 FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGFBP1 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC107131209 LOC112442231 LOC112446726 LOC510193 LOC515697 LOC518495 LOC521214 LOC524576 LOC531557 LOC786352 LOC788334 LTBP1 MADM MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MGAT4A MIA3 MXRA8 NUCB1 P4HB PDIA6 PENK PI PNPLA2 PRKCSH PROC PRSS23 RCN1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPIND1 SHISA5 SPARCL1 SPP1 SPP2 SPP24 STC2 TF TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1	Bos taurus (cattle)
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase, tissue-nonspecific isozyme Alkaline phosphatase Alkaline phosphatase Alkaline phosphatase CAMPATH-1 antigen CPM protein Carcinoembryonic antigen related cell adhesion molecule 1 Carcinoembryonic antigen related cell adhesion molecule 1 Contactin 3 Contactin 4 Contactin-5 Doppel protein Folate receptor 2 (Fetal) Glycoprotein 2 Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 2 LY6/PLAUR domain containing 4 LY6/PLAUR domain containing 5 LY6/PLAUR domain containing 8 Low affinity immunoglobulin gamma Fc region receptor III-A Lymphocyte antigen 6 complex locus protein G6c Lymphocyte antigen 6 complex, locus E Lymphocyte antigen 6 family member H Lymphocyte antigen 6D MAM domain containing glycosylphosphatidylinositol anchor 1 MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein MHC class I-like antigen recognition-like domain-containing protein Melanotransferrin NAD(P)(+)--arginine ADP-ribosyltransferase NAD(P)(+)--arginine ADP-ribosyltransferase Neuritin Neuronal growth regulator 1 Neurotrimin Opioid-binding protein/cell adhesion molecule Otoancorin Pantetheinase Phosphatidylinositol-glycan-specific phospholipase D Placenta-expressed transcript 1 protein Prostate stem cell antigen Reticulon 4 receptor like 2 Reversion inducing cysteine rich protein with kazal motifs Serine protease 21 Shadow of prion protein Sperm acrosome membrane-associated protein 4 TEX101 protein Tectorin alpha Tectorin beta Thy-1 cell surface antigen UL16 binding protein 21 UL16-binding protein 17 ULBP13 Vanin 2 X-prolyl aminopeptidase 2 alkaline phosphatase alkaline phosphatase	A0A140T891 A0A3Q1LX90 A0A3Q1M3B5 A0A3Q1M7Z2 A0A3Q1MCB1 A0A3Q1MKY1 A0A3Q1MPP4 A0A3Q1MQ27 A0A3Q1MYV4 A0A452DIP5 A0A452DIY1 A0A452DJA6 A0JNL5 A0RZB4 A6QP04 A6QPE3 A6QQ36 A7MBD9 A7U7N6 E1B735 E1B7U4 E1B8I3 E1BCI6 E1BE12 E1BG25 E1BGM5 E1BI14 E1BJE3 F1MDR2 F1MHX8 F1MLP3 F1MNM2 F1MPH8 F1MQX6 F1MRK8 F1MTV3 F1MUR6 F1MZE6 F1N2M5 F1N3U5 F1N6T5 F1N726 F6RUZ4 G3MZX4 G3N030 G3N0F4 G3N2K2 G3X7K3 G5E5F5 G5E5L3 G5E5X5 P09487 P11834 P79107 Q09YM2 Q09YM5 Q0VCN9 Q148C3 Q1RMM2 Q29RK7 Q2KIC6 Q32PB3 Q3SX33 Q56JW8 Q58DA5	ALPI ALPL ART3 ART4 BST1 C15H11orf34 CD52 CEACAM1 CNTN3 CNTN4 CNTN5 CPM FCGR3 FCGR3A FCGRIII FOLR2 GP2 GPIHBP1 GPLD1 LOC100336941 LOC100850276 LOC516378 LOC528262 LOC783508 LSAMP LY6D LY6E LY6G6C LY6H LYPD1 LYPD2 LYPD4 LYPD5 LYPD8 MDGA1 MELTF NEGR1 NRN1 NT NTM OBCAM OCAM OPCML OTOA PRND PRSS21 PSCA RECK RTN4RL2 SPACA4 SPRN TECTA TECTB TEX101 THY1 ULBP13 ULBP17 ULBP21 VNN1 VNN2 XPNPEP2	Bos taurus (cattle)
Platelet homeostasis	P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase 2, cytoplasmic	E1B742 E1BIH1 E1BIP1 F1MUF3 F1MVZ6 F1N7A9 P79106 Q5E9U1	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Bos taurus (cattle)
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin, cytoplasmic 2 Albumin Alpha-1-acid glycoprotein Alpha-1-antiproteinase Alpha-1B-glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-4 Amyloid-beta A4 protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 C-X-C motif chemokine C-type lectin domain family 3 member B CD63 antigen CD9 antigen CYFIP-related Rac1 interactor B Calmodulin-like Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor VIII Coagulation factor XIII A chain Complement factor D EF-hand domain-containing protein ENDOD1 protein FIGF protein Fermitin family homolog 3 Fibronectin Filamin A Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine-rich repeat protein Insulin-like growth factor I Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Left-right determination factor Lymphocyte antigen 6 complex locus G6F Lysosomal associated membrane protein 2 MAGE family member D2 MICOS complex subunit MIC27 Mesencephalic astrocyte-derived neurotrophic factor Multimerin 1 NADH-cytochrome b5 reductase 1 NHL repeat-containing protein 2 NTR domain-containing protein Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Prosaposin Protein FAM3C Proteoglycan 1-like Protocadherin 7 Ras-related protein Rab-27B Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selenoprotein P Serotransferrin Serpin family G member 1 Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 Talin 1 Thrombospondin 1 Thymosin beta Torsin family 4 member A Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Transgelin-2 Tubulin alpha-4A chain Vascular endothelial growth factor A Vascular endothelial growth factor B Vascular endothelial growth factor C Vinculin Vitamin K-dependent protein S WD repeat domain 1 p-selectin protein disulfide-isomerase von Willebrand factor	A0A140T843 A0A140T897 A0A140T8C6 A0A140T8C8 A0A1L6ZA12 A0A3Q1LMG1 A0A3Q1LN74 A0A3Q1LTE4 A0A3Q1LUG2 A0A3Q1M2H1 A0A3Q1MHJ9 A0A3Q1MLQ7 A0A3Q1MQV3 A0A3Q1MR28 A0A3Q1N449 A0A3Q1N8P4 A0A452DIJ9 A0A452DIU4 A0A452DIX0 A4FV53 A4IF69 A4IFA6 A5D7D1 A5PK28 A5PKI3 A6H754 A6QL97 A6QLI2 A6QP91 A6QPF9 A7E3W2 A7MBB6 A7YY77 B1H0W5 E1B726 E1B8Z0 E1BBY0 E1BCK4 E1BH14 E1BMJ0 F1MD83 F1MGZ4 F1MHC2 F1MK25 F1MKS5 F1MLH6 F1MNQ4 F1MRZ8 F1MTN1 F1MTP5 F1MUC1 F1MW44 F1MX05 F1MY12 F1MZ40 F1MZD6 F1N0I3 F1N0R5 F1N169 F1N789 F6QVC9 F6RT22 G3X6N3 G3X7J5 G5E5A9 G5E5W1 G8JKY5 P00442 P07224 P07455 P07456 P12763 P13213 P15497 P15691 P17697 P21214 P26201 P28800 P30932 P34955 P49907 P56652 P63258 P80513 P81948 Q17QL4 Q27967 Q29RS5 Q2HJ33 Q2KJ15 Q2KJF1 Q2KJI3 Q32LP0 Q3B7N2 Q3MHW9 Q3SZ27 Q3T0A3 Q3ZC55 Q56K11 Q5E9F5 Q5EAB4 Q5GN72 Q8HZJ5 Q9XS49 Q9XS50 Q9XSK2	A1BG ACTG ACTG1 ACTN1 ACTN2 ACTN4 AGP AHSG ALB ALDOA ANXA5 APOA1 APOH APOL APP ARMET ARP BRPF3 CALM CD36 CD63 CD9 CDC37L1 CFD CHID1 CLEC3B CLU CTSW CYB5R1 CYRIB ENDOD1 F13A1 F5 F8 FAM121A FAM3C FAM49B FERMT3 FETUA FIGF FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 ILEI ISLR ITGA2B ITGB3 ITIH3 KIND3 KNG1 LAMP2 LEFTY2 LGALS3BP LHFPL2 LOC112442231 LOC515333 MAGED2 MANF MIC27 MMRN1 NHLRC2 OLA1 ORM1 PAS4 PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PI PLEK PLG PLI PPBP PROS PROS1 PSAP RAB27B RARRES2 SCCPDH SCG3 SELENOP SELP SERPINA1 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SPP24 SRGN STXBP2 SYTL4 TAGLN2 TF TGFB1 TGFB2 TGFB3 THBS1 TLN1 TMSB4X TMX3 TOR4A TUBA1 TUBA4A URP2 VCL VEGF VEGFA VEGFB VEGFC VEGFD VRF VWF WDR1 agp ly6g6f	Bos taurus (cattle)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	A0A452DI66 E1B863 E1BG29 F1N0R5 F1N1G4	F2 GP1BB GP5 GP9 VWF	Bos taurus (cattle)
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2	Bos taurus (cattle)
Phosphorylation of CD3 and TCR zeta chains	BOLA-DQA1 protein BoLA-DR-alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase CSK Tyrosine-protein kinase peptidylprolyl isomerase protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A3Q1M088 A0A3Q1M3D2 A0A3Q1M6K1 A0A3Q1MT21 A6H6Y1 A6QQE7 E1BLZ1 F1MJK4 F1MJS9 F1MJU5 F1ML60 F1MQC1 F1N0X9 F1N6L3 G3MWT2 G8JL01 Q0VBZ0 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD3D CD3E CD3G CD4 CSK DYB HLA-DRA LCK LOC100848815 PAG1 PTPN22 PTPRC PTPRJ TRAV29-1	Bos taurus (cattle)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1MPT9 A0MTF4 D8KXU9 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 Fgf4 HBGF-1 PLCG1	Bos taurus (cattle)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 HBGF-1 PLCG1	Bos taurus (cattle)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho	A0A3Q1LUE0 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BAI2 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MYF9 F1N6G8 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF17 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF5 FGF5C FGF6 FGF7B FGF8 FGF9 FGFA FGFR1 Fgf4 HBGF-1 KL PLCG1	Bos taurus (cattle)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase Alpha/beta hydrolase fold-3 domain-containing protein Amine oxidase [copper-containing] 3 Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like CYB5B protein Carbonyl reductase (NADPH) Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily B member 6 Epoxide hydrolase Mitochondrial amidoxime reducing component 1 Mitochondrial amidoxime reducing component 2 NAD(P)H dehydrogenase, quinone 2 NADH-cytochrome b5 reductase 3 Primary amine oxidase, liver isozyme	A0A3Q1LGS8 A0A3Q1LKX3 A0A3Q1LZ03 A0A3Q1M7J3 A0A3Q1MQJ1 A0A3Q1MU42 A0A452DHX8 E1BC09 F1MFG7 F1MI11 F1ML85 F1MU22 F1MYL2 F1N015 G3X6I4 G3X6X4 G5E6I5 P07514 Q0P5F6 Q0VC97 Q1LZH1 Q29437 Q29RV2 Q3MHQ1 Q3SZT2 Q3T047 Q3ZCJ6 Q9TTK6	AADAC ABP1 AHR ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5R3 CYP2B6 CYP3A28 CYP3A4 CYP3A5 CYP3A74 CYP3A76 DIA1 EPHX1 LOC100138645 MARC2 MOSC2 MTARC1 MTARC2 NQO2	Bos taurus (cattle)
Phase 4 - resting membrane potential	ATP-sensitive inward rectifier potassium channel 12 Inward rectifier potassium channel 2 Potassium channel subfamily K member 1 Potassium channel subfamily K member 9 Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member Potassium inwardly rectifying channel subfamily J member 14 Potassium inwardly rectifying channel subfamily J member 4 Potassium two pore domain channel subfamily K member 10 Potassium two pore domain channel subfamily K member 12 Potassium two pore domain channel subfamily K member 13 Potassium two pore domain channel subfamily K member 15 Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 18 Potassium two pore domain channel subfamily K member 2 Potassium two pore domain channel subfamily K member 4 Potassium two pore domain channel subfamily K member 5	A0A3Q1LQ50 A0A3Q1M4V6 A0A3Q1MT89 E1B9M4 E1BCI4 E1BEH1 E1BEH3 E1BGH7 E1BIA3 E1BNW6 F1MLI5 F1MW24 G3N1D1 G3N1Q6 O19182 Q0P5A0 Q4TZY1 Q8HZT2	IRK1 KCNJ12 KCNJ14 KCNJ2 KCNJ4 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK18 KCNK2 KCNK3 KCNK4 KCNK5 KCNK7 KCNK9	Bos taurus (cattle)
Phase 2 - plateau phase	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 KCNE1-like MinK-related peptide 3 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily KQT member 1 Uncharacterized protein Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A3Q1LKG2 A0A3Q1MT75 A2VDV8 E1BGG9 E1BIG3 E1BLK4 F1MV40 F1MX37 F1N5T3 Q0IIF1 Q2KHV0 Q2NKS7 Q9MZL5 Q9MZL7	CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8 KCNE1 KCNE1L KCNE2 KCNE3 KCNE4 KCNE5 KCNQ1	Bos taurus (cattle)
Phase 1 - inactivation of fast Na+ channels	Kv channel-interacting protein 4 Potassium voltage-gated channel interacting protein 1 Potassium voltage-gated channel interacting protein 2 Potassium voltage-gated channel interacting protein 3 Potassium voltage-gated channel subfamily D member 1 Potassium voltage-gated channel subfamily D member 2 Potassium voltage-gated channel subfamily D member 3	A0A3Q1LV43 A0A3Q1M5I5 A0A3Q1M784 F1MVI5 F1MY95 Q2KI69 Q52PG9	KCND1 KCND2 KCND3 KCNIP1 KCNIP2 KCNIP3 KCNIP4	Bos taurus (cattle)
Phase 0 - rapid depolarisation	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like EF-hand domain-containing protein Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor RAN guanine nucleotide release factor Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel protein Sodium channel regulatory subunit beta-3 Sodium channel subunit beta-1 Sodium channel subunit beta-4 Sodium voltage-gated channel beta subunit 2 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit calcium/calmodulin-dependent protein kinase	A0A3Q1LKG2 A0A3Q1LLX7 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1NE86 E1B757 E1B9G2 E1BHM6 E1BIG3 E1BLK4 E1BLM4 F1MHP0 F1MLH6 F1MV40 F1MW14 F1MX37 F1N5T3 F6QLW0 M0QVY7 M0QW12 Q08E08 Q17QN4 Q2HJF7 Q2KI11 Q3MHJ9 Q9MZL5 Q9MZL7	CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8 CALM CAMK2A CAMK2B CAMK2D FGF12 FGF13 FGF14 RANGRF SCN11A SCN1A SCN1B SCN2B SCN3A SCN3B SCN4B SCN5A SCN8A SCN9A	Bos taurus (cattle)
Peptide ligand-binding receptors	APLNR protein Adrenocorticotropic hormone receptor Angiotensinogen Apelin Atypical chemokine receptor 1 B1 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5L2 C5a anaphylatoxin chemotactic receptor 1 Cholecystokinin Coagulation factor II (Thrombin) receptor-like 2 Complement C3 Complement C5 Cortistatin Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 Endothelin-converting enzyme 2 F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 G protein-coupled receptor 37 like 1 G protein-coupled receptor 37 GALR2 protein Galanin peptides Galanin receptor 1 Galanin receptor 3 Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Interleukin-8 KISS1 receptor Kappa-type opioid receptor KiSS-1 metastasis suppressor Kininogen 1 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanocortin receptor 4 Melanocortin receptor 5 Melanocortin-3-receptor Melanocyte-stimulating hormone receptor Motilin receptor Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin B receptor Neuromedin S Neuromedin U receptor 1 Neuromedin U receptor 2 Neuropeptide B Neuropeptide S receptor 1 Neuropeptide S Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptides B and W receptor 1 Neuropeptides B/W receptor type 2 Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Nociceptin receptor Opioid receptor delta 1 Pancreatic polypeptide receptor 1 Pancreatic polypeptide Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin 1 Prokineticin 2 Prokineticin receptor 2 Prolactin-releasing peptide receptor Promotilin Prosaposin Proteinase-activated receptor 1 Prothrombin Somatostatin receptor 1 Somatostatin receptor type 2 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor	A0A140T858 A0A140T8C6 A0A140T8C8 A0A3Q1LWC2 A0A3Q1MCT6 A0A3Q1MSN3 A0A3Q1MXN7 A0A3Q1MXY0 A0A452DI66 A0A452DII4 A0A452DIK5 A0A452DJT3 A0A452DKE4 A1Z2Z3 A4IFB7 A4IFF5 A6QL98 A6QLK3 A6QLQ7 A6QM11 A6QQX6 B1H0W3 C3W8S1 E1B8V8 E1B9Q7 E1BCM7 E1BCZ7 E1BFS5 E1BFV6 E1BKZ6 E1BL07 E1BMI3 E1BMN4 F1MCC4 F1MEN6 F1MJD1 F1MJZ0 F1MKB6 F1MMX1 F1MN36 F1MPG4 F1MPN9 F1MV99 F1MWG2 F1MY53 F1MY85 F1N018 F1N083 F1N145 F1N476 F1N4J9 F1N4Y7 F1N5B6 G3N364 G3X795 G5E5J0 G5E6F7 O46639 O62647 P01017 P01156 P01190 P01211 P11242 P17322 P21450 P25104 P28088 P34974 P41520 P42891 P47798 P51694 P56451 P79255 Q08DZ7 Q0VD43 Q1RMU8 Q2KIP6 Q2UVX4 Q4EW11 Q673L2 Q6RUW3 Q863C3 Q867A9 Q8MJV2 Q8MJV4 Q8SPN1 Q9GLJ8	ACKR1 AGT AGTR1 AGTR2 APLN APLNR BDKRB2 BRS3 C3 C3AR1 C5 C5AR1 C5AR2 C5L2 CCK CCKBR CORT CXCL8 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 GAL GALN GALR1 GALR2 GALR3 GPR10 GPR37 GPR37L1 GPR73L1 GPR77 GPR8 GRP GRPR IL8 KISS1 KISS1R KNG1 LOC112445811 MC1R MC2R MC3R MC4R MC5R MCHR1 MCHR2 MLN MLNR MSHR NLN NMBR NMS NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPS NPSR1 NPY NPY1R NPY2R NPY4R NPY5R NTS NTSR1 NTSR2 OPRD1 OPRK1 OPRL1 OPRM1 PDYN PENK PKR2 PMCH PNOC POMC PPY PPYR1 PRLHR PROK1 PROK2 PROKR2 PSAP PYY SERPINA8 SST SSTR1 SSTR2 SSTR5 TRH TRHR mln	Bos taurus (cattle)
Peptide hormone biosynthesis	Neuroendocrine convertase 1 Pro-opiomelanocortin	F1MFR6 P01190	PCSK1 POMC	Bos taurus (cattle)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Deoxyribose-phosphate aldolase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase ribose-5-phosphate isomerase	A0A3Q1MM55 A0A3S5ZPM3 A0A3S5ZPP1 A5D7P1 A7Z014 E1BJH7 F1MM83 F6QEU6 G5E534 G5E5C8 Q3T0V9	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Bos taurus (cattle)	G31080DL
Passive transport by Aquaporins	Aquaporin 10 Aquaporin 5 Aquaporin 7 Aquaporin 8 Aquaporin 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin Aquaporin Lens fiber major intrinsic protein	A0A3Q1LWN9 A0A3S5ZPM1 E1BDW5 F1MNJ1 F1N1C3 F1N3R5 F1N7X5 O77750 P06624 P47865 P79099 Q08DE6	AQP1 AQP10 AQP11 AQP12 AQP2 AQP3 AQP4 AQP5 AQP6 AQP7 AQP8 AQP9 MIP	Bos taurus (cattle)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha	E1BA29 F1MSD7 F1N2V3 P10894 P38408 P38409	GNA11 GNA14 GNA15 GNAQ PLCB1 PLCB4	Bos taurus (cattle)
PKMTs methylate histone lysines	ASH1 like histone lysine methyltransferase ASH2 like, histone lysine methyltransferase complex subunit Activating transcription factor 7 interacting protein Euchromatic histone lysine methyltransferase 1 Histone H3.1 Histone H3.2 Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase SETD7 Histone-lysine N-methyltransferase SETDB2 Histone-lysine N-methyltransferase, H3 lysine-79 specific Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase Histone-lysine N-methyltransferase N-lysine methyltransferase KMT5A N-lysine methyltransferase SMYD2 NF-kappaB transcription factor p65 subunit NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear receptor binding SET domain protein 1 Nuclear receptor binding SET domain protein 2 Nuclear receptor binding SET domain protein 3 PR/SET domain 16 PR/SET domain 9 PR/SET domain 9 Polycomb protein EED RBBP5 protein SET domain bifurcated histone lysine methyltransferase 1 SET domain containing 1A, histone lysine methyltransferase SET domain containing 1B, histone lysine methyltransferase SET domain containing 6, protein lysine methyltransferase SUZ12 polycomb repressive complex 2 subunit WD repeat domain 5 Zinc finger protein AEBP2 [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-methyltransferase [histone H3]-lysine(4) N-trimethyltransferase [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B protein-histidine N-methyltransferase	A0A3Q1LX03 A0A3Q1M6A7 A0A3Q1M792 A0A3Q1M7L9 A0A3Q1MID6 A0A3Q1MJ82 A0A3Q1MSK4 A0A452DJ38 A1XG22 A4FUE3 A4FV57 A7MBB7 E1BEP4 E1BGA4 E1BKH5 E1BKN0 E1BLX2 E1BM66 E1BNH7 F1MHA1 F1MKW9 F1MMY4 F1MTF1 F1MUT0 F1MXG0 F1MYZ3 F1N093 F1N6Y5 F6R2J7 G3N3E5 G3X6G5 G3X6T4 G3X834 P62803 P68432 P84227 Q0P585 Q0P5C5 Q2YDJ8 Q3MHL3 Q3SWX8 Q3SZ25	AEBP2 ASH1L ASH2L ATF7IP DOT1L EED EHMT1 EZH2 KMT2A KMT2B KMT2C KMT5A KMT5B KMT5C NFKB1 NFKB2 NSD1 NSD2 NSD3 PRDM16 PRDM7 RBBP4 RBBP5 RBBP7 RELA SETD1A SETD1B SETD3 SETD6 SETD7 SETD8 SETDB1 SETDB2 SMYD2 SMYD3 SUV39H1 SUV39H2 SUZ12 WDR5	Bos taurus (cattle)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Calmodulin-like EF-hand domain-containing protein Protein kinase cAMP-dependent type I regulatory subunit beta adenylate cyclase cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A3Q1MA58 A0A3Q1MCI6 A0A3Q1MR28 A0A452DJE2 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MLH6 F1MPC9 P00514 P00515 P00517 P19754	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 CALM PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A	Bos taurus (cattle)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Alpha isoform of regulatory subunit A, protein phosphatase 2 Amphiregulin Betacellulin CD19 molecule CD80 molecule CD86 molecule Epiregulin Epithelial mitogen Estrogen receptor beta Estrogen receptor FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Immediate early response 3 Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 PIP5K1A protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-4-phosphate 5-kinase type 1 beta Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Phosphatidylinositol-5-phosphate 4-kinase type 2 beta Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein phosphatase 2 scaffold subunit Abeta Proto-oncogene vav Ras homolog family member G Ras-related C3 botulinum toxin substrate 2 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M535 A0A3Q1M7J4 A0A3Q1M864 A0A3Q1MBL1 A0A3Q1MCW9 A0A3Q1ME99 A0A3Q1MGW7 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MLL9 A0A3Q1MPT9 A0A3Q1N3Z8 A0A3Q1NAV6 A0A3Q1ND77 A0A3S5ZP81 A0A452DHW6 A0A452DHX3 A0JNB0 A0MTF4 A2VDZ0 A2VE24 A2VE27 A4FV68 A5D973 A5PJB2 A6QLC5 A6QLU3 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BDM2 E1BE66 E1BFL8 E1BFP8 E1BGY3 E1BHC1 E1BIM8 E1BIN8 E1BJU2 E1BP37 F1MCQ7 F1MDQ5 F1MEV4 F1MHC6 F1MHR4 F1MHT2 F1MJE0 F1MN51 F1MPD0 F1MQN0 F1MRU0 F1MRU1 F1MS28 F1MV64 F1MYE0 F1MYM3 F1MZD6 F1N1S8 F1N339 F1N4S9 F1N586 F1N6G8 F1N7M1 F2Z4J0 G3MXR4 G3N104 G3XGD3 P03968 P03969 P23726 P23727 P32871 P46196 P49884 P67774 Q08DN7 Q08DP7 Q08DU3 Q0P594 Q0P5F7 Q0P5G7 Q1RMI2 Q1RMT8 Q28132 Q2KJ15 Q2LGB3 Q3T0F9 Q3ZCC3 Q3ZCM0 Q58DF9 Q9TU25 Q9XSB5 Z4YHD9	AFGF AREG BTC CD19 CD28 CD80 CD86 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HBGF-1 HGF ICOS IER3 IL1RL1 IL33 INS INSR IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MAPK1 MAPK3 MET MYD88 NR3A1 NR3A2 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5D PPP2R5E PRKM1 PTPN11 RAC2 RHOG SCF SRC STRN TGFA TRAF6 TRAT1 VAV1	Bos taurus (cattle)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Amphiregulin Betacellulin CD19 molecule CD80 molecule CD86 molecule Epiregulin Epithelial mitogen Estrogen receptor beta Estrogen receptor FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene vav Ras homolog family member G Ras-related C3 botulinum toxin substrate 2 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M535 A0A3Q1M7J4 A0A3Q1M864 A0A3Q1MCW9 A0A3Q1ME99 A0A3Q1MGW7 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MLL9 A0A3Q1MPT9 A0A3Q1N3Z8 A0A3Q1NAV6 A0A3Q1ND77 A0A3S5ZP81 A0A452DHW6 A0A452DHX3 A0JNB0 A0MTF4 A2VE24 A2VE27 A6QLU3 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1BAI2 E1BBE2 E1BDM2 E1BE66 E1BFL8 E1BFP8 E1BGY3 E1BHC1 E1BIM8 E1BIN8 E1BJU2 E1BP37 F1MCQ7 F1MDQ5 F1MEV4 F1MHC6 F1MJE0 F1MN51 F1MPD0 F1MQJ7 F1MRU0 F1MRU1 F1MS28 F1MYE0 F1MYM3 F1MZD6 F1N339 F1N4S9 F1N586 F1N6G8 F2Z4J0 G3MXR4 G3N104 G3XGD3 P03968 P03969 P23726 P23727 P32871 P49884 Q08DN7 Q08DU3 Q1RMI2 Q1RMT8 Q28132 Q2KJ15 Q2LGB3 Q3T0F9 Q3ZCC3 Q3ZCM0 Q58DF9 Q9TU25 Q9XSB5 Z4YHD9	AFGF AREG BTC CD19 CD28 CD80 CD86 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HBGF-1 HGF ICOS IL1RL1 IL33 IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MET MYD88 NR3A1 NR3A2 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTPN11 RAC2 RHOG SCF SRC STRN TGFA TRAF6 TRAT1 VAV1	Bos taurus (cattle)

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