GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Beta-1,4-galactosyltransferase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 (Neuroglycan C) Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Hexosyltransferase Neurocan Syndecan-1 Syndecan-2 Syndecan Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	A0A3Q1LG25 A0A3Q1LSF3 A0A3Q1LTY7 A0A3Q1LZ29 E1BKJ2 E1BKS1 F1MCX1 F1MQ31 F1MQ60 F1MVH6 F1MY84 F1MZX8 F1N211 F1N2Y8 F6Q1U8 P21793 P21809 P81282 Q08DZ5 Q0VCM1 Q3ZBZ6 Q58DD4	AGRN B3GALT6 B3GAT1 B3GAT3 B4GALT7 BCAN BGN CSPG2 CSPG4 CSPG5 DCN GPC1 GPC2 GPC3 GPC4 GPC5 NCAN SDC1 SDC2 SDC4 VCAN XYLT1 XYLT2	Bos taurus (cattle)
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily B member 1 ATP binding cassette subfamily B member 4 ATP binding cassette subfamily B member 9 ATP binding cassette subfamily C member 10 ATP binding cassette subfamily C member 11 ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 ATP binding cassette subfamily C member 9 ATP binding cassette subfamily F member 1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Derlin-1 Derlin Derlin E3 ubiquitin-protein ligase RNF E3 ubiquitin-protein ligase RNF Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin-2 Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Multidrug resistance-associated protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Retinal-specific phospholipid-transporting ATPase ABCA4 SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LQI5 A0A3Q1LV78 A0A3Q1LZ87 A0A3Q1MB23 A0A3Q1ME24 A0A3Q1NB13 A0A452DI44 A0A452DIY4 A2VDS4 A4IFC2 A7MBA2 E1BD83 E1BLT5 E1BNL1 F1MBI1 F1MGJ5 F1MGK3 F1MIP7 F1MLV1 F1MN01 F1MS86 F1MUC1 F1MWE0 F1MWM0 F1MX65 F1MXE4 F1MYH8 F1MZD4 F1N3Y6 F1N4I6 F1N6Z0 F6PVF9 G3N0U8 G3X757 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 P68102 Q17QP9 Q1RMU4 Q2KHU8 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q71SS4 Q8HXQ5	ABCA4 ABCB1 ABCB4 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC5 ABCC9 ABCF1 ABCR CFTR DERL1 DERL2 DERL3 EIF2A EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 KCNJ11 LOC515333 MRP1 OS9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RNF185 RNF5 RPS27A SEL1L SPFH2 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP	Bos taurus (cattle)
ABO blood group biosynthesis	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Galactoside alpha-(1,2)-fucosyltransferase 1 L-Fucosyltransferase	A0A3Q1M8N6 F1MUS1 F6Q1T7	ABO FUT1 FUT2	Bos taurus (cattle)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma P2Y purinoceptor 1 Tyrosine-protein kinase mitogen-activated protein kinase	A0A3Q1LTT9 A0A3Q1NGS8 A0A3S5ZPL0 A4IFJ5 A4IFL6 A5PKD6 E1B8Q3 E1BA29 E1BIM8 F1MYW8 F1N2V3 P02698 P11017 P30671 P38408 P38409 P48042 P50154 P62871 P63212 P63214 P63217 Q28024 Q3SZ98 Q5E9F0	CPLA2 GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 MAPK14 P2RY1 PLA2G4 PLA2G4A SRC	Bos taurus (cattle)
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 Arylamine N-acetyltransferase 1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytosolic non-specific dipeptidase Glutathione S-transferase theta-1 Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Glutathione hydrolase 7 Glutathione hydrolase Glutathione hydrolase Multidrug resistance-associated protein 1 N-acyl-aliphatic-L-amino acid amidohydrolase Sulfotransferase 1A1 Sulfotransferase Sulfotransferase Sulfotransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase	A0A3Q1LMV5 A0A3Q1LWZ2 A0A3Q1LYU5 A0A3Q1MIN6 A0A3Q1MP36 A0A452DHY4 A1A4L7 B2D1N9 E1BBB3 E1BJU8 F1MFF6 F1MIP7 F1MR63 F1MUC1 F1MYJ3 F1MZD4 F1N0S6 F1N3Y6 G3N2D8 P50227 Q0V8L2 Q1JPA6 Q2NL00 Q3ZC30 Q3ZC84 Q8HXQ5	ABCC1 ABCC2 ABCC3 ABCC5 ABCG2 ACY1 CNDP2 GGT1 GGT5 GGT7 GGTL3 GSTM4 GSTP1 GSTT1 LOC100138004 LOC100138908 LOC100296421 LOC100300896 LOC515333 MRP1 NAT1 STP SULT1A1 SULT1E1 SULT2A1 UGT2B10	Bos taurus (cattle)
APC/C:Cdc20 mediated degradation of Securin	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 16 Cell division cycle 20 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M862 A0A3Q1MAR8 A0A452DI44 A0A452DIY4 A1A4R8 A7MBA2 A7Z061 E1B945 E1BAB6 E1BD83 E1BK11 E1BM34 E1BPM5 F1MBI1 F1MLV1 F1MRW5 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 F2Z4G9 G3N1P6 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q1RML1 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA10 Q2YDE4 Q32KL2 Q32PA5 Q3MHN0 Q3SX30 Q3SZ19 Q3SZ31 Q3SZC2 Q3SZT7 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF6 Q3ZCK9 Q58DR0 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 CDC16 CDC20 CDC23 CDC26 CDC27 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S	Bos taurus (cattle)
APC/C:Cdc20 mediated degradation of mitotic proteins	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 BUB1 mitotic checkpoint serine/threonine kinase B Cell division cycle 16 Cell division cycle 20 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Mitotic arrest deficient 2 like 1 Mitotic checkpoint protein BUB3 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A3Q1M862 A0A3Q1MAR8 A1A4R8 A7Z061 E1B945 E1BAB6 E1BK11 E1BM34 E1BPM5 F1MRW5 F1MWP1 F2Z4G9 G3MX31 G3N1P6 Q1JQB2 Q1RML1 Q2TA10 Q32PA5 Q3SZ31 Q3SZT7 Q3ZCF6 Q58DR0	ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 BUB1B BUB3 CDC16 CDC20 CDC23 CDC26 CDC27 MAD2L1 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S	Bos taurus (cattle)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase Cell division cycle 16 Cell division cycle 20 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Fizzy/cell division cycle 20 related 1 (Drosophila) Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta RB transcriptional corepressor 1 SKP2 protein Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M862 A0A3Q1MAR8 A0A452DI44 A0A452DIY4 A1A4R8 A7MB09 A7MBA2 A7Z061 E1B945 E1BAB6 E1BD83 E1BK11 E1BM34 E1BPM5 F1MBI1 F1MD46 F1MLV1 F1MRW5 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 F2Z4G9 G3N1P6 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q08DN4 Q17QP9 Q1RML1 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA06 Q2TA10 Q2TA25 Q2YDE4 Q32KL2 Q32L05 Q32PA5 Q3MHN0 Q3SX30 Q3SZ19 Q3SZ31 Q3SZC2 Q3SZT7 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF6 Q3ZCK9 Q58DR0 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	AIK AIRK1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 ARK1 AURA AURKA AURKB AYK1 BTAK CDC16 CDC20 CDC23 CDC26 CDC27 FZR1 IAK1 PLK1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RB1 RPS27A SKP2 STK15 STK6 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S	Bos taurus (cattle)
ATF6 (ATF6-alpha) activates chaperones	Activating transcription factor 6 MBTPS1 protein Membrane-bound transcription factor site-2 protease	F1MDD8 Q08E55 Q0III2	ATF6 MBTPS1 MBTPS2	Bos taurus (cattle)
ATF6B (ATF6-beta) activates chaperones	ATF6B protein MBTPS1 protein Membrane-bound transcription factor site-2 protease	A4FUY2 Q08E55 Q0III2	ATF6B MBTPS1 MBTPS2	Bos taurus (cattle)
AUF1 (hnRNP D0) binds and destabilizes mRNA	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Eukaryotic translation initiation factor 4 gamma 1 Heat shock 70 kDa protein 1A Heat shock cognate 71 kDa protein Heat shock protein beta-1 Heteroous nuclear ribonucleoprotein D Polyadenylate-binding protein 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M8I4 A0A452DI44 A0A452DIY4 A7MBA2 E1BD83 F1MBI1 F1MLV1 F1MWE0 F1MX04 F1MXE4 F1MYH8 F1N6Z0 G5E589 P0CG53 P0CH28 P19120 P33672 P56701 P61286 P62194 P62992 P63048 Q17QP9 Q27975 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3T149 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	EIF4G1 HNRNPD HSC70 HSP27 HSP70-1 HSPA1A HSPA8 HSPB1 PABP1 PABPC1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A7MBE0 E1BHW6 F1MXY3	OCT1 SLC22A1 SLC22A2 SLC22A3	Bos taurus (cattle)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 18 member A3 Solute carrier family 5 (Choline transporter), member 7 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 E1BIA1 E1BK36 F1MLQ5 F1N7B7 P11023 P32850 P48018 P61763 P63026 Q0IIL7 Q17QQ3 Q2KI26	CHAT CPLX1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC18A3 SLC5A7 SNAP25 STX1A STXBP1 SYB2 SYT1 UNC13B UNC18A VAMP2	Bos taurus (cattle)
Acrosome Reaction and Sperm:Oocyte Membrane Binding	Acrosin CD9 antigen IZUMO family member 2 IZUMO family member 4 Izumo sperm-egg fusion protein 3 Izumo sperm-oocyte fusion 1	A6QL94 E1BC82 E1BDA8 F1MYA6 G5E5C6 P30932	ACR CD9 IZUMO1 IZUMO2 IZUMO3 IZUMO4	Bos taurus (cattle)
Activated NTRK3 signals through PI3K	Neurotrophin-3 Tyrosine-protein kinase receptor Tyrosine-protein kinase	E1BIM8 G3N3T6 Q08DT3	NTF3 NTRK3 SRC	Bos taurus (cattle)
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Neurotrophin-3 Tyrosine-protein kinase receptor	F1MYF9 G3N3T6 Q08DT3	NTF3 NTRK3 PLCG1	Bos taurus (cattle)
Activation of C3 and C5	Complement C2 Complement C3 Complement C5 Complement component 4A Complement factor B Uncharacterized protein	E1BH06 F1MVK1 F1MY85 P81187 Q2UVX4 Q3SYW2	BF C2 C3 C4A C5 CFB LOC107131209	Bos taurus (cattle)
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 12 G protein subunit beta 3 G protein subunit gamma 13 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 4 GNB4 protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 2 KCNJ10 protein KCNJ15 protein Potassium inwardly rectifying channel subfamily J member 16 Potassium inwardly rectifying channel subfamily J member 4	A0A3Q1M4V6 A0A3Q1NGS8 A0A3S5ZPL0 A2VDQ4 A4IFL6 A5PJL2 A5PKD6 E1B8Q3 E1BNE9 F1MF15 F1MIZ5 F1MUD1 F1MYR9 F1MYW8 O19182 P02698 P11017 P30671 P50154 P62871 P63212 P63214 P63217 Q0VD28 Q28024 Q3SZ98 Q4TZY1 Q5E9F0	GABBR1 GABBR2 GIRK1 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 IRK1 KCNJ10 KCNJ12 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6	Bos taurus (cattle)
Activation of Matrix Metalloproteinases	72 kDa type IV collagenase Cathepsin K Collagen type XVIII alpha 1 chain Collagenase 3 Elastase, neutrophil expressed Glandular kallikrein Matrix metallopeptidase 11 Matrix metallopeptidase 15 Matrix metallopeptidase 16 Matrix metallopeptidase 17 Matrix metallopeptidase 24 Matrix metallopeptidase 25 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Metalloproteinase inhibitor 2 NTR domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Plasma kallikrein Plasminogen Procathepsin L Stromelysin-1 TPSB1 protein chymotrypsin furin interstitial collagenase trypsin	A6QPI9 A7YWU6 A7YWU9 B0JYR0 E1B726 E1B8U1 E1BAD2 E1BH36 E1BIP7 F1MHG1 F1MKH8 F1MMD4 F1MT97 F1MTK6 F1MTX6 F1MU56 F1MW26 F1MY12 F1N1E3 F1N1F5 F1N430 F1N6W9 F1N797 G3MWP1 G3N0J0 P25975 P52176 Q2KJ63 Q5E968 Q6H320	COL18A1 CTRB1 CTSK CTSL CTSL1 ELANE FURIN KLK1 KLKB1 KLNA1 LOC100139881 LOC112441463 LOC112442231 LOC509956 LOC540321 MMP11 MMP13 MMP14 MMP15 MMP16 MMP17 MMP2 MMP24 MMP25 MMP3 MMP7 MMP8 MMP9 PLG PRSS2 TIMP2 TPSB1	Bos taurus (cattle)
Activation of NF-kappaB in B cells	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell CLL/lymphoma 10 Caspase recruitment domain family member 11 Cullin 1 F-box and WD repeat domain containing 11 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta MALT1 paracaspase NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit NFKB inhibitor epsilon Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein kinase C beta type REL proto-onco, NF-kB subunit S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M118 A0A3S5ZPB2 A0A452DI44 A0A452DIY4 A1XG22 A7MBA2 E1BD83 F1MBI1 F1MBS7 F1MJH6 F1MKW9 F1MLV1 F1MVS1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N6Z0 G5E589 P05126 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q0IIB2 Q17QJ6 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	BCL10 CARD11 CHUK CUL1 FBXW11 IKBKB IKBKG IKKA MALT1 NEMO NFKB1 NFKBIA NFKBIB NFKBIE PRKCB PRKCB1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 REL RELA RPS27A SKP1 SKP1A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 bIkBa	Bos taurus (cattle)
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Cyclic nucleotide-gated channel alpha-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Phosphodiesterase Phosphodiesterase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin	E1B957 E1BK80 F1MTS7 P02698 P02699 P04695 P04972 P62871 Q00194	CNCG CNCG1 CNGA1 CNGB1 GNAT1 GNB1 GNGT1 PDE6A PDE6B PDE6G PDEG RHO	Bos taurus (cattle)
Acyl chain remodelling of PC	Cytosolic phospholipase A2 LPCAT4 protein Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 2 Lysophospholipid acyltransferase 5 Lysoplasmalogenase TMEM86B Membrane bound O-acyltransferase domain containing 2 PLA2G12A protein Patatin like phospholipase domain containing 8 Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor phospholipase A2 phospholipase A2	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1MPE0 A0A3Q1NMD6 A0JNE8 A4IFJ5 A5D7L0 E1BB89 E1BE78 E1BEM2 E1BGU4 F1MG30 F1MH02 F1MNU5 F1MSG5 F1MTK4 G8JL05 P00593 P49259 Q3T0W0 Q56JZ2 Q9GL30	CPLA2 LOC613966 LPCAT1 LPCAT2 LPCAT3 LPCAT4 MBOAT2 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G3 PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2G6 PLA2R1 PLBD1 PNPLA8 TMEM86B	Bos taurus (cattle)
Acyl chain remodelling of PE	Abhydrolase domain containing 4, N-acyl phospholipase B Cytosolic phospholipase A2 HRASLS5 protein LPCAT4 protein Lysophospholipid acyltransferase 5 Membrane bound O-acyltransferase domain containing 1 Membrane bound O-acyltransferase domain containing 2 PLA2G12A protein Patatin like phospholipase domain containing 8 Phospholipase A and acyltransferase 1 Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor phospholipase A2 phospholipase A2	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1NMD6 A0A452DIS9 A0JNE8 A4IFJ5 A5D7L0 E1BB89 E1BE78 E1BEM2 E1BGU4 E1BNI4 F1MG30 F1MH02 F1MNU5 F1MSG5 F6QAQ8 G8JL05 P00593 P49259 Q32KQ8 Q56JZ2 Q9GL30	ABHD4 CPLA2 HRASLS5 LOC613966 LPCAT3 LPCAT4 MBOAT1 MBOAT2 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G3 PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2G6 PLA2R1 PLAAT1 PLAAT5 PLBD1 PNPLA8	Bos taurus (cattle)
Acyl chain remodelling of PG	Cytosolic phospholipase A2 LPCAT4 protein LPGAT1 protein Lysophosphatidylcholine acyltransferase 1 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Secretory phospholipase A2 receptor cardiolipin synthase (CMP-forming) phospholipase A2	A0A3Q1MNU5 A0JNE8 A4IFJ5 A4IFP8 A5D7L0 A5PJS7 E1BEM2 E1BGU4 F1MG30 F1MNU5 F1MSG5 F1MTK4 P00593 P49259 Q56JZ2	CPLA2 CRLS1 LOC613966 LPCAT1 LPCAT4 LPGAT1 PLA2G12A PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G3 PLA2G4 PLA2G4A PLA2G4D PLA2G4F PLA2R1	Bos taurus (cattle)
Acyl chain remodelling of PI	Cytosolic phospholipase A2 Lysophospholipid acyltransferase 7 PLA2G12A protein Phospholipase A2, group XVI Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like 1 Secretory phospholipase A2 receptor	A0A3Q1LYR5 A0A3Q1MNU5 A0A3Q1NMD6 A4IFJ5 A5D7L0 E1BGU4 F1MG30 F1MNU5 F1MSG5 P00593 P49259 Q0VCY6 Q56JZ2 Q9GL30	CPLA2 LENG4 LOC613966 MBOAT7 OACT7 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2G4E PLA2G4F PLA2R1 PLBD1	Bos taurus (cattle)

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