GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **268** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Golgi associated PDZ and coiled-coil motif containing Ras homolog family member Q	A0A8I3Q881 A0A8I3RUU0 A0A8I3RV68 Q5U820	ABCC7 CFTR GOPC RHOQ	Canis familiaris (dog)
Synthesis of bile acids and bile salts	Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Retinoic acid receptor RXR	A0A8I3N2S7 A0A8I3NA48 A0A8I3NIH7 A0A8I3NPK5 A0A8I3NS93 A0A8I3P033 A0A8I3P4G5 A0A8I3PNT4 A0A8I3PRC4 A0A8I3PYI4 A0A8I3S236 A0A8I3S5H8 A0A8I3SAZ3	CYP7A1 CYP7B1 NCOA1 NCOA2 NR1H4 OSBP OSBPL1A OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RXRA	Canis familiaris (dog)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Cytochrome P450 family 8 subfamily B member 1 Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase carbonyl reductase (NADPH) glutathione transferase	A0A8I3MUQ9 A0A8I3PFY5 A0A8I3PJM8 A0A8I3PV18 A0A8I3Q8L4 A0SYQ0 B4YY03 E5RQH2 Q8HZR1 Q8SPQ9	CBR1 COX-2 COX1 CYP8B1 H-PGDS HPGDS PGES PTGDS PTGES PTGES2 PTGIS PTGS1 PTGS2 TBXAS1	Canis familiaris (dog)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 G protein subunit alpha transducin 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Glucagon Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Leptin	A0A8I3MH22 A0A8I3P5C5 A0A8I3PJF2 A0A8I3PQY2 A0A8I3Q958 A0A8I3QXE0 A0A8I3QZL6 A0A8I3RQW9 A0A8I3S964 P62872 P79147	DPP4 FFAR1 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP LEP	Canis familiaris (dog)	G58161NS
Synaptic adhesion-like molecules	Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 Flotillin Flotillin Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor Leucine rich repeat and fibronectin type III domain containing 1 Leucine rich repeat and fibronectin type III domain containing 2 Leucine rich repeat and fibronectin type III domain containing 4 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Receptor-type tyrosine-protein phosphatase F Reticulon protein-tyrosine-phosphatase	A0A8I3MHF6 A0A8I3MLF1 A0A8I3MYK4 A0A8I3N069 A0A8I3N2F7 A0A8I3N7W4 A0A8I3NEU9 A0A8I3NRD6 A0A8I3NUJ0 A0A8I3NVY0 A0A8I3NZA0 A0A8I3P9B8 A0A8I3PJ11 A0A8I3PXY0 A0A8I3QNS7 A0A8I3RRH4 A0A8I3RS83 A0A8I3S101 Q5R1P0 Q5R1P3	DLG1 DLG3 DLG4 FLOT1 FLOT2 GRIA1 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D LRFN1 LRFN2 LRFN3 LRFN4 NMDAR1 PTPRD PTPRF RTN3	Canis familiaris (dog)
Thyroxine biosynthesis	Dual oxidase 1 Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 NAD(P)H oxidase (H2O2-forming) Solute carrier family 5 member 5 Thyroid peroxidase Thyrotropin subunit beta	A0A0F7RPW1 A0A8I3P5E5 A0A8I3PAJ8 A0A8I3PWH8 A0A8I3Q1X1 A0A8I3QSW1 Q9MZF4	CGA DUOX1 DUOX2 GPA1 IYD SLC5A5 THOX1 TPO TSHB	Canis familiaris (dog)
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit guidance ligand 2	A0A8I3NQC4 Q9TSZ6	DAG1 SLIT2	Canis familiaris (dog)
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine rich repeats and immunoglobulin like domains 1 SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase ubiquitinyl hydrolase 1	A0A8I3MBU4 A0A8I3MMN5 A0A8I3MZ64 A0A8I3N2P0 A0A8I3N8H2 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGY1 A0A8I3NKR3 A0A8I3NRM5 A0A8I3NTR3 A0A8I3P598 A0A8I3PMU1 A0A8I3PNU1 A0A8I3PT69 A0A8I3PXV2 A0A8I3Q5C2 A0A8I3QYD0 P63050 Q867B7	CBL EPS15 GRB2 HGF HGS LRIG1 MET PTPN1 PTPN2 PTPRJ RPS27A SH3GL1 SH3GL2 SH3KBP1 STAM STAM2 UBA52 UBB UBC UBCEP2 USP8	Canis familiaris (dog)
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MBU4 A0A8I3MIK8 A0A8I3MMN5 A0A8I3MP09 A0A8I3NFB9 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3PZP0 A0A8I3QYD0 A0A8I3RQD0 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P63050 P79150 Q20FD0	CBL FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 GRB2 KGF MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC UBCEP2	Canis familiaris (dog)
Negative regulation of FGFR3 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MBU4 A0A8I3MIK8 A0A8I3MMN5 A0A8I3NFB9 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3PZP0 A0A8I3QYD0 A0A8I3RQD0 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 P63050 Q20FD0	CBL FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 GRB2 MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC UBCEP2	Canis familiaris (dog)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C SH2B adaptor protein 2 SH2B adaptor protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A8I3MBU4 A0A8I3ML64 A0A8I3MTK2 A0A8I3NAC6 A0A8I3P3X1 A0A8I3PT69 A0A8I3PUN0 A0A8I3PUQ8 A0A8I3PWC6 A0A8I3QRG3 A0A8I3S3D9 A0A8I3SBF9 O97799 Q06220	CBL FYN GRB2 KIT KITLG LCK LYN MGF PRKCA PTPN6 SH2B2 SH2B3 SOS1 SRC YES1	Canis familiaris (dog)
Sodium/Calcium exchangers	EF-hand domain-containing protein Sodium/calcium exchanger 1 Solute carrier family 24 member 2 Solute carrier family 24 member 3 Solute carrier family 24 member 4 Solute carrier family 24 member 5 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Solute carrier family 8 member B1 Sorcin	A0A8I3MSQ7 A0A8I3MTJ5 A0A8I3NPM6 A0A8I3NX53 A0A8I3PDR2 A0A8I3PJY1 A0A8I3Q687 A0A8I3RTF4 A0A8I3RY81 P23685	CALM2 NCX1 SLC24A2 SLC24A3 SLC24A4 SLC24A5 SLC8A1 SLC8A2 SLC8A3 SLC8B1 SRI	Canis familiaris (dog)
EPH-Ephrin signaling	EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B2 Uncharacterized protein receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I3MB23 A0A8I3MBN5 A0A8I3MD88 A0A8I3MVS4 A0A8I3N250 A0A8I3NEL5 A0A8I3NQ24 A0A8I3NR10 A0A8I3NS68 A0A8I3NYD1 A0A8I3PTE3 A0A8I3PZY2 A0A8I3Q5U0 A0A8I3QB00 A0A8I3RP21 A0A8I3RVX4 A0A8I3RZP3 A0A8I3S0G7 A0A8I3SCP8 B0LDS6	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB2 EPHB3 EPHB4 EPHB6 efnB2	Canis familiaris (dog)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Toll-like receptor 9 Toll-like receptor 9 Uncharacterized protein non-specific serine/threonine protein kinase	A0A8I3MWD3 A0A8I3PJ50 A0A8I3PZW3 A0A8I3Q7B4 A0A8I3QFN1 Q5I2M8	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Canis familiaris (dog)
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 5 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I3MUC6 A0A8I3NVH4 A0A8I3PDX4 A0A8I3PSA1 A0A8I3RS40 A0A8I3RV66 A0A8I3RXB9 A0A8I3S4Z2 A0A8I3S6B0 A0A8I3SBB2 O77762 P41148 Q95LF0 Q9N0W9	GRP94 HSP90B1 HSPC4 IL13 IL13RA1 IL13RA2 IL4 IL4R JAK1 JAK2 JAK3 SOCS5 STAT1 STAT3 STAT6 TRA1 TYK2	Canis familiaris (dog)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor	A0A8I3MAV6 A0A8I3RRT3	ESR1 ESR2	Canis familiaris (dog)
Vitamin B2 (riboflavin) metabolism	FAD synthase Riboflavin transporter Riboflavin transporter Tartrate-resistant acid phosphatase type 5 Uncharacterized protein riboflavin kinase	A0A8I3NBD2 A0A8I3NDY6 A0A8I3P1H5 A0A8I3RQK2 A0A8I3S1B1 E2RBY6	ACP5 ENPP1 FLAD1 RFK SLC52A2 SLC52A3	Canis familiaris (dog)
FCGR activation	Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MFY1 A0A8I3ML64 A0A8I3MV98 A0A8I3NEM6 A0A8I3NQX3 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P3X1 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QHH1 A0A8I3QQ00 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S4F9 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 A0A8I3SBF9 E2RP87	CD247 CD3G FCGR1A FCGR2B FCGR3A FGR FYN HCK LOC478984 LYN SRC SYK YES1	Canis familiaris (dog)
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Toll-like receptor 9 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MWD3 A0A8I3N971 A0A8I3N9M7 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWT3 A0A8I3Q7B4 A0A8I3QFN1 A0A8I3RTN7 A0A8I3S0I1 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0 Q5I2M8	FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 GAB1 GAB2 GRB2 IRS1 IRS2 KGF KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Canis familiaris (dog)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NM39 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 FRS3 GRB2 HRAS KGF KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR2	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3N971 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 GAB1 GRB2 KGF PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 GRB2 HRAS KGF KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
FRS-mediated FGFR3 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NM39 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 FRS3 GRB2 HRAS KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
PI-3K cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha Tyrosine-protein phosphatase non-receptor type Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3N971 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3NXI8 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 FRS2 GAB1 GRB2 PIK3CA PIK3R1 PTPN11	Canis familiaris (dog)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GRB2 HRAS KRAS NRAS SHC1 SOS1	Canis familiaris (dog)

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