GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **268** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Sphingolipid de novo biosynthesis	3-dehydrosphinganine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 heme-binding domain-containing protein Delta 4-desaturase, sphingolipid 2 Fatty acid 2-hydroxylase Major facilitator superfamily domain containing 2B Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 ORM1-like protein ORM1-like protein ORM1-like protein SPNS lysolipid transporter 2, sphingosine-1-phosphate Serine palmitoyltransferase 1 Serine palmitoyltransferase long chain base subunit 2 Serine palmitoyltransferase long chain base subunit 3 Sphingolipid delta(4)-desaturase DES1 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Uncharacterized protein Uncharacterized protein	A0A8I3MDB1 A0A8I3MDX2 A0A8I3MH69 A0A8I3MTG4 A0A8I3MVV0 A0A8I3MZT5 A0A8I3N0C8 A0A8I3N1I8 A0A8I3N6A8 A0A8I3N8H8 A0A8I3NCL9 A0A8I3NE51 A0A8I3NF48 A0A8I3P1Y0 A0A8I3P1Z6 A0A8I3P4B7 A0A8I3PAM7 A0A8I3PG24 A0A8I3PM33 A0A8I3PMG7 A0A8I3PQ53 A0A8I3Q2P7 A0A8I3S0D0 A0A8I3S194 A0A8I3S6X3 A0A8I3S790 B3RFJ1 Q6UR05	ABCC1 ABCG2 Abcg2 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CYB5B DEGS1 DEGS2 FA2H KDSR MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPNS2 SPTLC1 SPTLC2 SPTLC3 SPTSSA	Canis familiaris (dog)
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 7 Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Neurocan Sulfotransferase Versican core protein	A0A8I3MD46 A0A8I3MZ05 A0A8I3N108 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NAW4 A0A8I3NGD4 A0A8I3NHS7 A0A8I3NUF9 A0A8I3NUH2 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3Q1Q4 A0A8I3Q2X9 A0A8I3Q6I3 A0A8I3RX33 E2RLE9 Q29393	BCAN BGN CHPF CHPF2 CHST11 CHST12 CHST13 CHST3 CHST7 CHST9 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 CSPG4 CSPG5 DCN DCN1C NCAN VCAN	Canis familiaris (dog)
Passive transport by Aquaporins	Aquaporin 10 Aquaporin 12 Aquaporin 8 Aquaporin 9 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin Lens fiber major intrinsic protein Uncharacterized protein	A0A8I3MCV0 A0A8I3N7P7 A0A8I3NP65 A0A8I3NT67 A0A8I3P6A6 A0A8I3P7C5 A0A8I3PD19 A0A8I3PFQ0 A0A8I3QCN1 A0A8I3S111 A2IBY8 Q9N2J4	AQP0 AQP1 AQP10 AQP11 AQP12 AQP2 AQP3 AQP4 AQP6 AQP7 AQP8 AQP9 MIP	Canis familiaris (dog)
Lewis blood group biosynthesis	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A8I3MCT3 A0A8I3NB27 A0A8I3NB67 A0A8I3NFY5 A0A8I3NLH2 A0A8I3NR40 A0A8I3NRD0 A0A8I3P0Y9 A0A8I3PNT8 A0A8I3PQF7 A0A8I3Q8H7 A0A8I3RVW4 A0A8I3S1H8 Q5TJE8 Q659L1	B3GALT2 B3GALT4 B3GALT5 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT5 FUT7 FUT9 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Canis familiaris (dog)	G39211DH G81971FM G83633HB G90387AM G98173LG
Glycosphingolipid biosynthesis	Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 1 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase ceramide glucosyltransferase	A0A8I3MCT3 A0A8I3MQ19 A0A8I3MWM9 A0A8I3MXG6 A0A8I3NA60 A0A8I3NB27 A0A8I3NFU6 A0A8I3NNC5 A0A8I3NPC1 A0A8I3NTR2 A0A8I3P0Y9 A0A8I3PUA8 A0A8I3PVY1 A0A8I3QHY8 A0A8I3RSF2 Q5TJE8	A4GALT B3GALNT1 B3GALT4 B4GALNT1 B4GALT5 B4GALT6 CERK FUT2 ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8	Canis familiaris (dog)
Collagen degradation	5-phosphohydroxy-L-lysine phospho-lyase 72 kDa type IV collagenase Cathepsin B Cathepsin D Collagen type XII alpha 1 chain Collagen type XIII alpha 1 chain Collagen type XIX alpha 1 chain Collagen type XV alpha 1 chain Collagen type XVIII alpha 1 chain Collagen type XXV alpha 1 chain Collagen type XXVI alpha 1 chain Collagenase 3 Matrix metallopeptidase 12 Matrix metallopeptidase 15 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Stromelysin-1 Transmembrane serine protease 6 furin interstitial collagenase trypsin	A0A8I3MCQ8 A0A8I3MGS0 A0A8I3MJI6 A0A8I3MND9 A0A8I3MSY3 A0A8I3MWG8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N1T9 A0A8I3N1V6 A0A8I3N4V8 A0A8I3NL35 A0A8I3P478 A0A8I3PD99 A0A8I3PHE2 A0A8I3QKG6 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3RVF8 A0A8I3S0M3 Q4LAL9 Q6Y4Q5	COL12A1 COL13A1 COL15A1 COL18A1 COL19A1 COL25A1 COL26A1 CTSB CTSD FURIN MMP1 MMP12 MMP13 MMP14 MMP15 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 PHYKPL PRSS2 TMPRSS6	Canis familiaris (dog)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase domain 8 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Alpha-2-macroglobulin Basigin Brevican core protein CD44 antigen Cadherin-1 Cadherin-1 Calpain 10 Calpain 11 Calpain 12 Calpain 13 Calpain 14 Calpain 15 Calpain 5 Calpain 6 Calpain 9 Calpain catalytic domain-containing protein Calpain catalytic domain-containing protein Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin G Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein D Matrix metallopeptidase 11 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 20 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 Nidogen 1 Opticin Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A8I3MCQ8 A0A8I3MDF9 A0A8I3MEZ7 A0A8I3MGS0 A0A8I3MM49 A0A8I3MND9 A0A8I3MS95 A0A8I3MTX4 A0A8I3MUT8 A0A8I3MWY2 A0A8I3MX21 A0A8I3MXC2 A0A8I3N8Z0 A0A8I3NAW1 A0A8I3NBM1 A0A8I3NET5 A0A8I3NF92 A0A8I3NG54 A0A8I3NHT2 A0A8I3NK04 A0A8I3NLH7 A0A8I3NNE0 A0A8I3NQ99 A0A8I3P0M4 A0A8I3P0U1 A0A8I3P1W2 A0A8I3P478 A0A8I3P4K7 A0A8I3P533 A0A8I3P8U9 A0A8I3PAG9 A0A8I3PCF8 A0A8I3PED9 A0A8I3PJW4 A0A8I3PMD6 A0A8I3PRM5 A0A8I3PVS1 A0A8I3Q3A2 A0A8I3Q5H9 A0A8I3QPC2 A0A8I3RPH1 A0A8I3RPK2 A0A8I3RU13 A0A8I3S3W1 A0A8I3S676 A0A8I3S9F9 A0A8I3SBJ8 E2FGH7 F1PAA9 Q29393 Q6Y4Q5 Q8MJD1 Q9GL24	A2M ACAN ADAM10 ADAM15 ADAM8 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS1 CAST CD44 CDH1 CTSG CTSL CTSL1 CTSS DCN DCN1C ELA2 ELANE HTRA1 KLK7 KLND MMP1 MMP11 MMP12 MMP13 MMP14 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 NID1 OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6	Canis familiaris (dog)
MET activates PTK2 signaling	Focal adhesion kinase 1 Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 3 Laminin subunit alpha 4 Multiple EGF like domains 6 Tyrosine-protein kinase	A0A8I3MC22 A0A8I3MMP8 A0A8I3NFG9 A0A8I3NGY1 A0A8I3NMY1 A0A8I3PA47 A0A8I3PGZ1 A0A8I3SBF9 Q867B7	HGF ITGA2 ITGA3 ITGB1 LAMA4 MEGF6 MET PTK2 SRC	Canis familiaris (dog)
ECM proteoglycans	Aggrecan core protein Agrin Biglycan Brevican core protein Cartilage oligomeric matrix protein Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Decorin Dentin matrix acidic phosphoprotein 1 Dentin sialophosphoprotein Fibronectin type-III domain-containing protein Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 7 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha V Matrilin 1 Matrilin 3 Matrilin 4 Neurocan Plasminogen activator inhibitor 1 SPARC Tenascin C Tenascin R Versican core protein Vitronectin	A0A8I3MC22 A0A8I3MDS4 A0A8I3MMP8 A0A8I3MS95 A0A8I3MWF4 A0A8I3N567 A0A8I3N600 A0A8I3N8Z0 A0A8I3NBB5 A0A8I3NFV4 A0A8I3NG24 A0A8I3NJU0 A0A8I3NL86 A0A8I3NUF9 A0A8I3P2A0 A0A8I3P4U9 A0A8I3P613 A0A8I3P787 A0A8I3P874 A0A8I3PAS0 A0A8I3PHY6 A0A8I3PLC3 A0A8I3PMU9 A0A8I3PZR7 A0A8I3QCJ7 A0A8I3RVA0 A0A8I3RVR5 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0V6 A0A8I3S0V9 A0A8I3S700 E2DP67 Q29393	ACAN AGRN BCAN BGN COL9A1 COL9A2 COL9A3 COMP DCN DCN1C DMP1 DSPP HAPLN1 ITGA2 ITGA2B ITGA7 ITGA8 ITGA9 ITGAD ITGAV ITGB1 ITGB3 ITGB5 ITGB6 MATN1 MATN3 MATN4 NCAN SEBOX SERPINE1 SPARC TNC TNR VCAN	Canis familiaris (dog)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cadherin-1 Cartilage oligomeric matrix protein Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin 1 Fibronectin Ig-like domain-containing protein Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 3 Integrin subunit alpha 4 Integrin subunit alpha 5 Integrin subunit alpha 6 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha E Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein Junctional adhesion molecule 3 Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Mucosal vascular addressin cell adhesion molecule 1 Platelet and endothelial cell adhesion molecule 1 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 Vascular cell adhesion molecule 1 Vitronectin	A0A8I3MC22 A0A8I3MCY9 A0A8I3MJI6 A0A8I3MMP8 A0A8I3MQ67 A0A8I3N050 A0A8I3N567 A0A8I3NBM1 A0A8I3NFG9 A0A8I3NFV4 A0A8I3NG24 A0A8I3NL86 A0A8I3NM06 A0A8I3NNW2 A0A8I3NNX0 A0A8I3NS51 A0A8I3NUR7 A0A8I3NV00 A0A8I3NXU0 A0A8I3P0Q0 A0A8I3P1W2 A0A8I3P4K7 A0A8I3P4U9 A0A8I3P613 A0A8I3P684 A0A8I3P787 A0A8I3P7W0 A0A8I3PCF8 A0A8I3PCH7 A0A8I3PED8 A0A8I3PEP1 A0A8I3PHE2 A0A8I3PI20 A0A8I3PJI8 A0A8I3PMU9 A0A8I3PNK7 A0A8I3PPU8 A0A8I3PRY8 A0A8I3PUD7 A0A8I3PZA9 A0A8I3PZR7 A0A8I3Q3A8 A0A8I3Q413 A0A8I3Q8L7 A0A8I3QCJ7 A0A8I3RVE5 A0A8I3RVR5 A0A8I3RW71 A0A8I3RZG7 A0A8I3S0U4 A0A8I3S0V6 A0A8I3S131 A0A8I3S2B2 A0A8I3S700 A0A8I3S8N4 A0A8I3SBL1 E2DP67 F1PAA9	BSG CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM3 LOC119867047 LUM MADCAM1 PECAM1 SEBOX SPP1 THBS1 TNC VCAM1	Canis familiaris (dog)
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine rich repeats and immunoglobulin like domains 1 SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase ubiquitinyl hydrolase 1	A0A8I3MBU4 A0A8I3MMN5 A0A8I3MZ64 A0A8I3N2P0 A0A8I3N8H2 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGY1 A0A8I3NKR3 A0A8I3NRM5 A0A8I3NTR3 A0A8I3P598 A0A8I3PMU1 A0A8I3PNU1 A0A8I3PT69 A0A8I3PXV2 A0A8I3Q5C2 A0A8I3QYD0 P63050 Q867B7	CBL EPS15 GRB2 HGF HGS LRIG1 MET PTPN1 PTPN2 PTPRJ RPS27A SH3GL1 SH3GL2 SH3KBP1 STAM STAM2 UBA52 UBB UBC UBCEP2 USP8	Canis familiaris (dog)
Regulation of KIT signaling	E3 ubiquitin-protein ligase CBL Growth factor receptor bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C SH2B adaptor protein 2 SH2B adaptor protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A8I3MBU4 A0A8I3ML64 A0A8I3MTK2 A0A8I3NAC6 A0A8I3P3X1 A0A8I3PT69 A0A8I3PUN0 A0A8I3PUQ8 A0A8I3PWC6 A0A8I3QRG3 A0A8I3S3D9 A0A8I3SBF9 O97799 Q06220	CBL FYN GRB2 KIT KITLG LCK LYN MGF PRKCA PTPN6 SH2B2 SH2B3 SOS1 SRC YES1	Canis familiaris (dog)
Na+/Cl- dependent neurotransmitter transporters	Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent glycine transporter 1 Solute carrier family 18 member A1 Solute carrier family 18 member A2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 6 member 13 Solute carrier family 6 member 6 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A8I3MBP6 A0A8I3MM56 A0A8I3MNK2 A0A8I3N6A1 A0A8I3N7M6 A0A8I3NCF6 A0A8I3NLL1 A0A8I3P2T9 A0A8I3PHP5 A0A8I3PME4 A0A8I3PQT8 A0A8I3PSN6 A0A8I3PV06 A0A8I3Q066 A0A8I3QQP1 A0A8I3QS48 A0A8I3RV00 A0A8I3S5V8 P27799	SLC18A1 SLC18A2 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9	Canis familiaris (dog)
MHC class II antigen presentation	ADP-ribosylation factor AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma Actin related protein 10 Actin related protein 1B Alpha-centractin CD74 molecule Calnexin Carboxypeptidase Cathepsin B Cathepsin D Cathepsin E Cathepsin F Cathepsin O Cathepsin S Centromere protein E Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain domain-containing protein Clathrin heavy chain Clathrin light chain Cytoplasmic dynein 1 intermediate chain 2 Dipeptidyl peptidase 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein cytoplasmic 1 heavy chain 1 Dynein cytoplasmic 1 intermediate chain 1 Dynein light chain Dynein light chain Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha F-actin-capping protein subunit alpha F-actin-capping protein subunit beta GTP-binding protein SAR1b Gamma-interferon-inducible lysosomal thiol reductase HLA class II histocompatibility antigen, DO alpha chain-like Kinesin associated protein 3 Kinesin family member 11 Kinesin family member 26A Kinesin family member 4A Kinesin family member 5A Kinesin light chain Kinesin light chain Kinesin light chain Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Legumain Lymphocyte activating 3 MHC class II DR alpha chain MHC class II antigen DM beta Major histocompatibility complex, class II, DM alpha Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Oxysterol-binding protein Pro-cathepsin H Procathepsin L Protein SEC13 homolog Protein transport protein SEC23 Protein transport protein Sec31A Queuine tRNA-ribosyltransferase catalytic subunit 1 Rab interacting lysosomal protein Rac GTPase activating protein 1 Ras-related protein Rab-7a SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SH3 domain containing GRB2 like 2, endophilin A1 Spectrin beta chain Uncharacterized protein Uncharacterized protein dynamin GTPase dynamin GTPase	A0A8I3MB83 A0A8I3MEF2 A0A8I3MGM6 A0A8I3MHS5 A0A8I3MQ01 A0A8I3MQ56 A0A8I3MSD7 A0A8I3MX81 A0A8I3MZR3 A0A8I3N2P7 A0A8I3N366 A0A8I3N413 A0A8I3N448 A0A8I3N536 A0A8I3N796 A0A8I3N7P9 A0A8I3N9C4 A0A8I3NBU3 A0A8I3NCI2 A0A8I3NCU8 A0A8I3NF50 A0A8I3NFH8 A0A8I3NH94 A0A8I3NHB2 A0A8I3NHV2 A0A8I3NIZ3 A0A8I3NMB7 A0A8I3NMT0 A0A8I3NPI1 A0A8I3NPK5 A0A8I3NPS2 A0A8I3NRM5 A0A8I3NTK0 A0A8I3NTV2 A0A8I3NUM0 A0A8I3NWA9 A0A8I3NX29 A0A8I3NYK0 A0A8I3NZH7 A0A8I3P2D4 A0A8I3P3K7 A0A8I3P4A1 A0A8I3P503 A0A8I3P5K8 A0A8I3P5S6 A0A8I3P8U9 A0A8I3P903 A0A8I3PA63 A0A8I3PC10 A0A8I3PDJ0 A0A8I3PFS2 A0A8I3PHA3 A0A8I3PK57 A0A8I3PQE6 A0A8I3PSF4 A0A8I3PSI0 A0A8I3PSI8 A0A8I3PSX7 A0A8I3PTU4 A0A8I3PVW4 A0A8I3PXL9 A0A8I3PZW5 A0A8I3Q2C8 A0A8I3Q4C7 A0A8I3Q5Y5 A0A8I3Q7H2 A0A8I3QA46 A0A8I3RR85 A0A8I3RSP2 A0A8I3RUA9 A0A8I3RZ95 A0A8I3S023 A0A8I3S0M3 A0A8I3S1I6 A0A8I3S2N1 A0A8I3S2X1 A0A8I3S449 A0A8I3S4X0 A0A8I3S565 A0A8I3S5V2 A0A8I3S7Q4 A0A8I3SB08 A0A8I3SB35 A0A8I3SCF9 A0A8I3SCQ9 P18067 P61162 Q4LAL9 Q5TJG5 Q5TJH0 Q9GL24	ACTR10 ACTR1A ACTR1B AP1B1 AP1M1 AP1M2 AP1S1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 CANX CAPZA2 CAPZA3 CAPZB CD74 CENPE CLTA CLTC CTRN1 CTSA CTSB CTSC CTSD CTSE CTSF CTSH CTSL CTSL1 CTSO CTSS DCTN1 DCTN3 DCTN4 DCTN5 DCTN6 DLA-DMA DLA-DMB DLA-DOA DLA-DQA1 DLA-DRA DNM1 DNM2 DNM3 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HLA-DQB2 IFI30 KIF11 KIF18A KIF20A KIF22 KIF23 KIF26A KIF2B KIF2C KIF3A KIF3C KIF4A KIF5A KIF5B KIFAP3 KLC1 KLC3 KLC4 LAG3 LGMN LOC100856399 LOC119868747 LOC119876190 LOC612266 OSBPL1A PHLPP2 QTRT1 RAB7 RAB7A RACGAP1 RILP SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SH3GL2 SPTBN2	Canis familiaris (dog)
EPH-Ephrin signaling	EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B2 Uncharacterized protein receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I3MB23 A0A8I3MBN5 A0A8I3MD88 A0A8I3MVS4 A0A8I3N250 A0A8I3NEL5 A0A8I3NQ24 A0A8I3NR10 A0A8I3NS68 A0A8I3NYD1 A0A8I3PTE3 A0A8I3PZY2 A0A8I3Q5U0 A0A8I3QB00 A0A8I3RP21 A0A8I3RVX4 A0A8I3RZP3 A0A8I3S0G7 A0A8I3SCP8 B0LDS6	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB2 EPHB3 EPHB4 EPHB6 efnB2	Canis familiaris (dog)
Cell surface interactions at the vascular wall	Apolipoprotein B CD2 molecule CD244 molecule CD44 antigen CD58 molecule CD74 molecule CD84 molecule CEA cell adhesion molecule 1 CEA cell adhesion molecule 20 CXADR Ig-like cell adhesion molecule E-selectin Endothelial cell adhesion molecule Epithelial cell adhesion molecule Fc alpha and mu receptor Fibronectin Glypican-1 Golgi apparatus protein 1 Growth arrest specific 6 High affinity immunoglobulin epsilon receptor subunit gamma Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Integrin beta Integrin beta Integrin subunit alpha 4 Integrin subunit alpha 5 Integrin subunit alpha D Integrin subunit alpha L Integrin subunit alpha M Joining chain of multimeric IgA and IgM Junction adhesion molecule like Junctional adhesion molecule 3 Junctional adhesion molecule A L-selectin Leukocyte surface antigen CD47 Macrophage migration inhibitory factor Oxidized low-density lipoprotein receptor 1 Platelet and endothelial cell adhesion molecule 1 Protein C receptor Prothrombin Selectin P ligand Selectin P Sialophorin Syndecan 4 Syndecan Syndecan Thrombomodulin Transforming growth factor beta Triggering receptor expressed on myeloid cells 1 Tyrosine-protein kinase Tyrosine-protein kinase UPAR/Ly6 domain-containing protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitamin K-dependent protein C Vitamin K-dependent protein S receptor protein-tyrosine kinase	A0A8I3MB16 A0A8I3MEX4 A0A8I3MFB3 A0A8I3MHM2 A0A8I3MHY1 A0A8I3MJX4 A0A8I3MMP8 A0A8I3MNI1 A0A8I3MNS0 A0A8I3MQ65 A0A8I3N050 A0A8I3N060 A0A8I3N3H1 A0A8I3N448 A0A8I3NG24 A0A8I3NKZ7 A0A8I3NQ82 A0A8I3NRC4 A0A8I3NS51 A0A8I3NUR7 A0A8I3NV00 A0A8I3NVW7 A0A8I3NWG4 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3T7 A0A8I3P3X1 A0A8I3P4F5 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P760 A0A8I3P941 A0A8I3PCF8 A0A8I3PCH7 A0A8I3PD67 A0A8I3PDU9 A0A8I3PED8 A0A8I3PIX4 A0A8I3PL11 A0A8I3PNK7 A0A8I3PQA6 A0A8I3PRY8 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWC1 A0A8I3PWK4 A0A8I3PWS3 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PXS2 A0A8I3PYF1 A0A8I3Q092 A0A8I3Q1K1 A0A8I3Q4U0 A0A8I3Q5B7 A0A8I3Q5E2 A0A8I3Q5Y3 A0A8I3Q8L7 A0A8I3QAV2 A0A8I3QAV8 A0A8I3QC57 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QM62 A0A8I3QSK6 A0A8I3QX83 A0A8I3RQK1 A0A8I3RVF3 A0A8I3RW25 A0A8I3RWV8 A0A8I3S0A6 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S2B2 A0A8I3S2M3 A0A8I3S4D1 A0A8I3S5W6 A0A8I3S6H5 A0A8I3S6W0 A0A8I3S8N4 A0A8I3S934 A0A8I3S9C3 A0A8I3SA76 A0A8I3SAS3 A0A8I3SAS7 Q28278	APOB B9D2 CD177 CD2 CD244 CD44 CD47 CD48 CD58 CD74 CD84 CEACAM1 CEACAM20 CXADR EPCAM ESAM F11R F2 FCAMR FCER1G FN1 FYN GAS6 GLG1 GP6 GPC1 ITGA4 ITGA5 ITGAD ITGAL ITGAM ITGB1 ITGB2 JAM3 JAML JCHAIN LOC119867047 LOC119868972 LYN MERTK MIF OLR1 PECAM1 PROC PROCR PROS1 SDC1 SDC3 SDC4 SELE SELL SELP SELPLG SIRPA SPN THBD TREM1	Canis familiaris (dog)
Cargo recognition for clathrin-mediated endocytosis	AP complex subunit beta AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Adaptin ear-binding coat-associated protein 1 Apolipoprotein B ArfGAP with FG repeats 1 Arginine vasopressin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 8 COP9 signalosome subunit 5 COP9 signalosome subunit 7A COP9 signalosome subunit 7B Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Clathrin heavy chain Clathrin heavy chain Clathrin light chain Clathrin light chain Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Frizzled-4 G protein pathway suppressor 1 G protein-coupled receptor kinase G protein-coupled receptor kinase Growth factor receptor bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Low-density lipoprotein receptor Mannose-6-phosphate receptor, cation dependent Muscarinic acetylcholine receptor NEDD8 Phosphatidylinositol binding clathrin assembly protein Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein Wnt RALBP1 associated Eps domain containing 1 RALBP1 associated Eps domain containing 2 Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin Synaptotagmin T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Torsin Torsin Trans-golgi network protein 2 Type-1 angiotensin II receptor Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vasopressin V2 receptor Vesicle associated membrane protein 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8	A0A8I3MAW6 A0A8I3MBG9 A0A8I3MBU4 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ91 A0A8I3MMN5 A0A8I3MQ56 A0A8I3MT64 A0A8I3MT80 A0A8I3MZG1 A0A8I3MZL3 A0A8I3N0H9 A0A8I3N1F4 A0A8I3N2C0 A0A8I3N2E5 A0A8I3N2P0 A0A8I3N399 A0A8I3N7P9 A0A8I3N8L8 A0A8I3N8T5 A0A8I3N970 A0A8I3NCI2 A0A8I3ND55 A0A8I3NE91 A0A8I3NF22 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NH32 A0A8I3NHL8 A0A8I3NHV2 A0A8I3NIR2 A0A8I3NKR3 A0A8I3NLC1 A0A8I3NPI2 A0A8I3NRM5 A0A8I3NS16 A0A8I3NTR3 A0A8I3NXQ1 A0A8I3NZX3 A0A8I3P087 A0A8I3P562 A0A8I3P6R3 A0A8I3P953 A0A8I3P9Q7 A0A8I3PCP2 A0A8I3PE10 A0A8I3PFJ2 A0A8I3PGA9 A0A8I3PGB9 A0A8I3PI71 A0A8I3PK82 A0A8I3PKW5 A0A8I3PMU1 A0A8I3PMU8 A0A8I3PP11 A0A8I3PPD9 A0A8I3PQE6 A0A8I3PRS1 A0A8I3PSX7 A0A8I3PT69 A0A8I3PV70 A0A8I3PVK3 A0A8I3PVM0 A0A8I3PWA8 A0A8I3Q314 A0A8I3Q374 A0A8I3Q3J5 A0A8I3Q545 A0A8I3Q5C2 A0A8I3Q5L9 A0A8I3QYD0 A0A8I3QZA5 A0A8I3RP69 A0A8I3RPS3 A0A8I3RR45 A0A8I3RTD0 A0A8I3RU23 A0A8I3RUS6 A0A8I3RV18 A0A8I3RV68 A0A8I3RYJ5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S1H6 A0A8I3S360 A0A8I3S4D1 A0A8I3S565 A0A8I3S6J8 A0A8I3S7E5 A0A8I3S9K7 A0A8I3SAF2 A0A8I3SBB3 B1H0W0 F1PHV6 P33705 P63050 Q5DUB3 Q5U820	AAK1 ABCC7 ADRB2 AGFG1 AGTR1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARRB1 ARRB2 AVP AVPR2 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CI-MPR/IGF2R CLTA CLTB CLTC CLTCL1 COPS2 COPS3 COPS5 COPS6 COPS7A COPS7B COPS8 DAB2 DVL2 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FZD4 GPS1 GRB2 GRK2 GRK3 HBEGF HGS IGF2R IL7R ITSN2 KIAA0319 LDLR LDLRAP1 LOC102156511 LOC119867035 LRP2 M6PR NECAP1 NECAP2 NEDD8 PICALM REPS2 RPS27A SCARB2 SH3GL1 SH3GL2 SH3KBP1 SLC18A3 SLC2A8 SNAP91 STAM STAM2 STON1 STON2 SYT1 SYT11 SYT2 SYT8 TACR1 TGFA TGOLN2 TOR1A TOR1B UBA52 UBB UBC UBCEP2 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 WNT5A	Canis familiaris (dog)
Clathrin-mediated endocytosis	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 6 AP complex subunit beta AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Amphiphysin Apolipoprotein B ArfGAP with FG repeats 1 Arginine vasopressin Arp2/3 complex 34 kDa subunit Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Bridging integrator 1 Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Clathrin heavy chain Clathrin heavy chain Clathrin light chain Clathrin light chain Cyclin G associated kinase Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 DnaJ heat shock protein family (Hsp40) member C6 E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Formin binding protein 1 Formin-binding protein 1-like Frizzled-4 GTPase activating protein and VPS9 domains 1 Growth factor receptor bound protein 2 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin interacting protein 1 related Huntingtin interacting protein 1 Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Low-density lipoprotein receptor Mannose-6-phosphate receptor, cation dependent Muscarinic acetylcholine receptor Phosphatidylinositol binding clathrin assembly protein Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein Wnt Protein kinase C and casein kinase substrate in neurons 1 Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Queuine tRNA-ribosyltransferase catalytic subunit 1 RALBP1 associated Eps domain containing 1 RALBP1 associated Eps domain containing 2 Ras-related protein Rab-5A Ras-related protein Rab-5C Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Sorting nexin 18 Sorting nexin 9 Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin Synaptotagmin T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Thyroid hormone receptor interactor 10 Trans-golgi network protein 2 Type-1 angiotensin II receptor Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vasopressin V2 receptor Vesicle associated membrane protein 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 WASP like actin nucleation promoting factor dynamin GTPase dynamin GTPase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase small monomeric GTPase	A0A8I3MAW6 A0A8I3MBG9 A0A8I3MBU4 A0A8I3MFQ5 A0A8I3MFY1 A0A8I3MIP1 A0A8I3MJ11 A0A8I3MJ91 A0A8I3MMN5 A0A8I3MNR2 A0A8I3MPK0 A0A8I3MPX3 A0A8I3MQ56 A0A8I3MQX2 A0A8I3MT64 A0A8I3MT80 A0A8I3MZG1 A0A8I3MZL3 A0A8I3N0H9 A0A8I3N156 A0A8I3N1F4 A0A8I3N1Q4 A0A8I3N1W7 A0A8I3N2E5 A0A8I3N2P0 A0A8I3N6A2 A0A8I3N7P9 A0A8I3N8J8 A0A8I3N8L8 A0A8I3N8T5 A0A8I3N970 A0A8I3NCI2 A0A8I3NCU8 A0A8I3ND55 A0A8I3NE45 A0A8I3NEW9 A0A8I3NF22 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NH32 A0A8I3NHL8 A0A8I3NHV2 A0A8I3NIE0 A0A8I3NKR3 A0A8I3NLC1 A0A8I3NNW3 A0A8I3NPI2 A0A8I3NRM5 A0A8I3NS16 A0A8I3NTR3 A0A8I3NW16 A0A8I3NXQ1 A0A8I3NZC2 A0A8I3NZX3 A0A8I3P087 A0A8I3P562 A0A8I3P6R3 A0A8I3P953 A0A8I3P9Q7 A0A8I3PFJ2 A0A8I3PFM7 A0A8I3PGA9 A0A8I3PGB9 A0A8I3PGP9 A0A8I3PJG5 A0A8I3PK72 A0A8I3PKW5 A0A8I3PLP7 A0A8I3PMU1 A0A8I3PMU8 A0A8I3PP11 A0A8I3PPD9 A0A8I3PPQ5 A0A8I3PQE6 A0A8I3PSX7 A0A8I3PT69 A0A8I3PWA8 A0A8I3PZW5 A0A8I3Q052 A0A8I3Q065 A0A8I3Q2I4 A0A8I3Q314 A0A8I3Q374 A0A8I3Q3J5 A0A8I3Q545 A0A8I3Q5C2 A0A8I3Q5L9 A0A8I3QYD0 A0A8I3QZA5 A0A8I3RP69 A0A8I3RPS3 A0A8I3RR45 A0A8I3RR73 A0A8I3RTD0 A0A8I3RU23 A0A8I3RUF5 A0A8I3RUS6 A0A8I3RV18 A0A8I3RV68 A0A8I3RYJ5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S1H6 A0A8I3S1K9 A0A8I3S1V5 A0A8I3S360 A0A8I3S4D1 A0A8I3S565 A0A8I3S6J8 A0A8I3S7E5 A0A8I3S7Q4 A0A8I3S7X1 A0A8I3S9K7 A0A8I3SAF2 A0A8I3SAR3 B1H0W0 F1PHV6 P18066 P33705 P51147 P63050 Q5DUB3 Q5U820	AAK1 ABCC7 ACTR2 ACTR3 ADRB2 AGFG1 AGTR1 AMPH AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARF6 ARFGAP1 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARRB1 ARRB2 AVP AVPR2 BIN1 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CI-MPR/IGF2R CLTA CLTB CLTC CLTCL1 DAB2 DNAJC6 DNM1 DNM2 DNM3 DVL2 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPVD1 GRB2 HBEGF HGS HIP1 HIP1R IGF2R IL7R ITSN2 KIAA0319 LDLR LDLRAP1 LOC102156511 LOC119867035 LOC607182 LRP2 M6PR NECAP1 NECAP2 OCRL PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C QTRT1 RAB5A RAB5B RAB5C REPS2 RPS27A SCARB2 SH3GL1 SH3GL2 SH3KBP1 SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 STAM STAM2 STON1 STON2 SYNJ1 SYNJ2 SYT1 SYT11 SYT2 SYT8 TACR1 TGFA TGOLN2 TRIP10 UBA52 UBB UBC UBCEP2 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 WASL WNT5A	Canis familiaris (dog)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor	A0A8I3MAV6 A0A8I3RRT3	ESR1 ESR2	Canis familiaris (dog)
Cargo concentration in the ER	Alpha 1 antitrypsin Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein Prolactin regulatory element-binding protein Protein cornichon homolog 2 Protein transport protein SEC23 SEC22 homolog B, vesicle trafficking protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Syntaxin 5 Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Vesicular integral-membrane protein VIP36 cathepsin X	A0A8I3MAV2 A0A8I3MLH1 A0A8I3MT80 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3N2I9 A0A8I3N5W4 A0A8I3N796 A0A8I3N9V0 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NYM5 A0A8I3NZH7 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PEN5 A0A8I3PQR9 A0A8I3PTW0 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RU45 A0A8I3RWZ7 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 P49256	AREG CD59 CNIH1 CNIH2 CNIH3 CTSC CTSZ F5 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 MIA2 PREB SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMED2	Canis familiaris (dog)
COPII-mediated vesicle transport	Alpha 1 antitrypsin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Casein kinase I isoform delta Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein NSF attachment protein alpha NSF attachment protein beta Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 2 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22 homolog A, vesicle trafficking protein SEC22 homolog B, vesicle trafficking protein SEC22 homolog C, vesicle trafficking protein SEC23 interacting protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Syntaxin 17 Syntaxin 5 TBC1 domain family member 20 Trafficking from ER to golgi regulator Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Trafficking protein particle complex subunit Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Vesicle-fusing ATPase Vesicular integral-membrane protein VIP36 YKT6 v-SNARE homolog cathepsin X small monomeric GTPase	A0A8I3MAV2 A0A8I3MJ74 A0A8I3MLH1 A0A8I3MLQ0 A0A8I3MT73 A0A8I3MT80 A0A8I3MUS5 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3MZY0 A0A8I3N2I9 A0A8I3N5A8 A0A8I3N5C1 A0A8I3N796 A0A8I3N7P4 A0A8I3N9C4 A0A8I3N9V0 A0A8I3NBA1 A0A8I3NCZ9 A0A8I3NFJ9 A0A8I3NKE3 A0A8I3NPG4 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NX57 A0A8I3NYM5 A0A8I3NZH7 A0A8I3NZS8 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PAS9 A0A8I3PEN5 A0A8I3PNK8 A0A8I3PQR9 A0A8I3PTJ0 A0A8I3PTW0 A0A8I3PU34 A0A8I3PV59 A0A8I3PVF9 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q4E7 A0A8I3Q5G1 A0A8I3Q7H2 A0A8I3QC45 A0A8I3QS42 A0A8I3RR85 A0A8I3RRF7 A0A8I3RSX1 A0A8I3RU45 A0A8I3RUA0 A0A8I3RVH6 A0A8I3RWZ7 A0A8I3RZB2 A0A8I3S3N8 A0A8I3S444 A0A8I3S449 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 E2QV03 P49256 P62822	ANKRD28 AREG BET1 CD59 CNIH1 CNIH2 CNIH3 CSNK1D CTSC CTSZ F5 GOLGA2 GORASP1 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 NAPA NAPB NAPG NSF PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A SCFD1 SEC13 SEC16A SEC16B SEC22A SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SERPINA1 STX17 STX5 TBC1D20 TFG TGFA TMED10 TMED2 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 USO1 YKT6	Canis familiaris (dog)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-3 Desmoplakin Occludin Plakophilin 1 Tight junction protein 1 Tight junction protein 2	A0A8I3MAQ1 A0A8I3NBM1 A0A8I3NIB1 A0A8I3NPT4 A0A8I3NRN4 A0A8I3NUM7 A0A8I3P212 A0A8I3RRA2 A0A8I3RW47 A0A8I3RY38 A0A8I3S0K7 F1PAA9 Q7YRU7	CASP3 CDH1 CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2	Canis familiaris (dog)
Initial triggering of complement	C4a anaphylatoxin Collectin subfamily member 10 Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MKD7 A0A8I3MRI0 A0A8I3NH95 A0A8I3NLF4 A0A8I3NQQ5 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PG15 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RST0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7	C1QA C1QB C1QC C1R C1S C2 COLEC10 FCN2 LOC481722 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
Regulation of Complement cascade	C3a anaphylatoxin chemotactic receptor C4a anaphylatoxin C5a anaphylatoxin chemotactic receptor 1 CD19 molecule Carboxypeptidase B2 Carboxypeptidase N subunit 1 Carboxypeptidase N subunit 2 Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor I Elastase, neutrophil expressed Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MAC-inhibitory protein Membrane cofactor protein Prothrombin Serpin family G member 1 Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Tetraspanin Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MDV8 A0A8I3MFV5 A0A8I3MKD7 A0A8I3MKJ7 A0A8I3MLF7 A0A8I3MPF4 A0A8I3MQ72 A0A8I3MQK6 A0A8I3MRL7 A0A8I3N180 A0A8I3N567 A0A8I3NC13 A0A8I3NH95 A0A8I3NLH3 A0A8I3NQA0 A0A8I3NQQ5 A0A8I3NT81 A0A8I3NVC1 A0A8I3NWR3 A0A8I3NYS7 A0A8I3P0T6 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PTW0 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q044 A0A8I3Q2F2 A0A8I3Q318 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RQ73 A0A8I3RQX0 A0A8I3RSI3 A0A8I3RSN2 A0A8I3RUJ7 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S1V7 A0A8I3S6H5 A0A8I3S7V8 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P25473 Q8MJD1	C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD19 CD55 CD59 CD81 CFB CFH CFHR5 CFI CLU CPB2 CPN1 CPN2 ELA2 ELANE F2 LOC102156626 LOC481722 LOC490269 SEBOX SERPING1	Canis familiaris (dog)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	Acyl-coenzyme A oxidase Bile acid-CoA Bile salt export pump Cytochrome P450 family 27 subfamily A member 1 Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Cytochrome P450 family 8 subfamily B member 1 Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 Hydroxysteroid 17-beta dehydrogenase 4 NADP-dependent oxidoreductase domain-containing protein Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Prostacyclin synthase Retinoic acid receptor RXR Sterol carrier protein 2 long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase palmitoyl-CoA hydrolase	A0A8I3MAI7 A0A8I3N1E1 A0A8I3N2S7 A0A8I3N3X9 A0A8I3NIH7 A0A8I3NZF5 A0A8I3P4G5 A0A8I3P7P8 A0A8I3PDX5 A0A8I3PFY5 A0A8I3PJM8 A0A8I3PRC4 A0A8I3PYI4 A0A8I3RWQ9 A0A8I3RZP4 A0A8I3S339 A0A8I3S6P6 A0A8I3SAZ3 B8K1W2	ACOT8 ACOX2 Abcb11e BAAT BSEP CYP27A1 CYP7A1 CYP7B1 CYP8B1 HSD17B4 HSD3B7 LOC119874618 NCOA1 NCOA2 NR1H4 PTGIS RXRA SCP2 SLC27A2 SLC27A5	Canis familiaris (dog)

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