GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **268** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Neutrophil degranulation	1-acyl-sn-glycerol-3-phosphate acyltransferase 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 6 26S proteasome regulatory subunit 7 ABC transporter domain-containing protein ADAM metallopeptidase domain 8 ADP ribosylation factor like GTPase 8A ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase AMP deaminase AP-1 complex subunit mu-1 AP-2 complex subunit alpha ATP-citrate synthase ATP-dependent 6-phosphofructokinase ATPase family AAA domain containing 3A Acetyl-CoA acyltransferase 1 Acid ceramidase Actin related protein 10 Actin related protein 1B Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Acylamino-acid-releasing enzyme Adenine phosphoribosyltransferase Adenylyl cyclase-associated protein Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Adhesion G protein-coupled receptor G3 Aldehyde dehydrogenase domain-containing protein Alpha 1 antitrypsin Alpha-1,4 glucan phosphorylase Alpha-1,4 glucan phosphorylase Alpha-1-B glycoprotein Alpha-1-acid glycoprotein Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-L-fucosidase Alpha-galactosidase Alpha-mannosidase Aminopeptidase Annexin A2 Anoctamin Apoptotic protease-activating factor 1 Arachidonate 5-lipoxygenase Arginase Armadillo repeat-containing protein 8 Arylsulfatase A Arylsulfatase B Aspartylglucosaminidase Bactericidal permeability-increasing protein Beta-1,4-galactosyltransferase Beta-2-microglobulin Beta-galactosidase Beta-glucuronidase Beta-hexosaminidase Bone marrow stromal antigen 2 Bridging integrator 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-type lectin domain family 4 member D C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 CD44 antigen CD58 molecule CD68 molecule CD93 molecule CEA cell adhesion molecule 1 CEA cell adhesion molecule 20 CKLF like MARVEL transmembrane domain containing 6 COMM domain containing 9 Calcium binding protein 39 Calcium release activated channel regulator 2A Calmodulin like 5 Calpain-1 catalytic subunit Calponin Carboxypeptidase Casein kinase II subunit beta Catalase Cathelicidin Cathepsin B Cathepsin D Cathepsin G Cathepsin S Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Cell cycle control protein Cellular repressor of E1A stimulated genes 1 Centrosomal protein 290 Chitinase-3-like protein 1 Choline transporter-like protein Chromosome 1 open reading frame 35 Coactosin like F-actin binding protein 1 Coatomer subunit beta Complement C3 Complement factor D Complement factor properdin Copine 3 Cullin-associated NEDD8-dissociated protein 1 Cyclin dependent kinase 13 Cystatin B Cysteine rich secretory protein LCCL domain containing 2 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoskeleton associated protein 4 DSN1 component of MIS12 kinetochore complex Dedicator of cytokinesis 2 Delta-aminolevulinic acid dehydratase Deoxyribonuclease Desmoglein 1 Desmoplakin Diaphanous related formin 1 Dipeptidyl peptidase 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ heat shock protein family (Hsp40) member C13 DnaJ homolog subfamily C member 3 DnaJ homolog subfamily C member 5 Docking protein 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dynein cytoplasmic 1 heavy chain 1 Dynein light chain Tctex-type 1 Dynein light chain Dynein light intermediate chain E3 ubiquitin-protein ligase KCMF1 Elastase, neutrophil expressed Elongation factor 1-alpha Elongation factor 1-alpha Endoplasmic reticulum protein 44 Eosinophil peroxidase Eukaryotic translation elongation factor 2 FERM and PDZ domain containing 3 Fas associated factor family member 2 Fatty acid-binding protein 5 Ferritin heavy chain Ferritin light chain Ferritin Fibrinogen C-terminal domain-containing protein Folate receptor-like domain-containing protein Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase G protein-coupled receptor 84 GH3 domain containing GTPase NRas Galectin 3 Galectin-3 Ganglioside GM2 activator Gasdermin D Gelsolin Glia maturation factor Globin A2 Glucose-6-phosphate isomerase Glutaminyl-peptide cyclotransferase Glutathione S-transferase Glutathione S-transferase Glycogen debranching enzyme Golgin subfamily A member 7 Grancalcin Granulin precursor HECT-type E3 ubiquitin transferase Heat shock 70 kDa protein 1 Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heme binding protein 2 Heparan-alpha-glucosaminide N-acetyltransferase catalytic domain-containing protein Heparanase High affinity immunoglobulin epsilon receptor subunit gamma High mobility group protein B1 IQ motif containing GTPase activating protein 2 IST1 homolog Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin C1-set domain-containing protein Inosine-5'-monophosphate dehydrogenase Inosine-5'-monophosphate dehydrogenase Integrin beta Integrin subunit alpha D Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Interleukin enhancer binding factor 2 Isocitrate dehydrogenase [NADP] Junction plakoglobin Karyopherin subunit beta 1 L-selectin Lactotransferrin LamG-like jellyroll fold domain-containing protein Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Leucine rich alpha-2-glycoprotein 1 Leucine rich repeat containing 7 Leukocyte immunoglobulin-like receptor subfamily B member 3 Leukocyte surface antigen CD47 Leukocyte-associated immunoglobulin-like receptor 1 Leukotriene A(4) hydrolase Lipocalin 2 Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Lysophosphatidylcholine acyltransferase 1 Lysosomal alpha-glucosidase Lysosomal associated membrane protein 1 Lysosomal associated membrane protein 2 Lysozyme C, spleen isozyme MAC-inhibitory protein MHC class I DLA-12 MHC class I DLA-64 MHC class I DLA-88 MHC class Ib Macrophage migration inhibitory factor Magnesium transporter protein 1 Major vault protein Malectin Maltase-glucoamylase Mast cell expressed membrane protein 1 Matrix metallopeptidase 25 Matrix metallopeptidase 8 Matrix metalloproteinase-9 Membrane protein BRI3 Membrane-associated progesterone receptor component 1 Metalloproteinase inhibitor 2 Microsomal glutathione S-transferase 1 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase Monocyte differentiation antigen CD14 Motile sperm domain containing 2 Multifunctional fusion protein Myeloid cell nuclear differentiation antigen Myeloperoxidase N-acetylgalactosamine-6-sulfatase N-acetylglucosamine-6-sulfatase NADH dehydrogenase [ubiquinone] 1 subunit C2 NADH-cytochrome b5 reductase 3 NCK associated protein 1 like NFAT activating protein with ITAM motif 1 NHL repeat containing 3 NPC intracellular cholesterol transporter 2 NPC intracellular cholesterol transporter 2 Natural resistance-associated macrophage protein 1 Neprilysin Neurobeachin like 2 Neurofascin Neuronal acetylcholine receptor subunit beta-4 Nicastrin Nicotinate phosphoribosyltransferase Nuclear factor NF-kappa-B p105 subunit Nuclear pore associated protein 1 Nucleoside diphosphate kinase B Nucleoside diphosphate kinase O-acyltransferase ORM1-like protein Olfactomedin 4 Omega-amidase NIT2 Osteoclast associated Ig-like receptor Osteoclast-stimulating factor 1 Oxidized low-density lipoprotein receptor 1 P2X purinoceptor PDGFA associated protein 1 PYD and CARD domain containing Pantetheinase Peptidoglycan-recognition protein Peptidyl-prolyl cis-trans isomerase A Peroxiredoxin-6 Phosphoglucomutase 2 Phosphoglycerate mutase Phospholipase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Placenta associated 8 Plakophilin 1 Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-activating factor acetylhydrolase IB subunit alpha2 Platelet-activating factor receptor Pleckstrin homology domain containing O2 Polymeric immunoglobulin receptor Presenilin Pro-cathepsin H Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Proliferation-associated 2G4 Prolylcarboxypeptidase Prosaposin Prostaglandin E synthase 2 Protease inhibitor Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Protein S100-A9 Protein S100 Protein kinase C delta type Protein yippee-like Protein-arginine deiminase Proteoglycan 3, pro eosinophil major basic protein 2 Purine nucleoside phosphorylase Pyridoxal kinase RAB24, member RAS oncogene family RAB37, member RAS oncogene family RAB44, member RAS oncogene family RAB9B, member RAS oncogene family RNA helicase Rab GDP dissociation inhibitor Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ras homolog family member F, filopodia associated Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-10 Ras-related protein Rab-18 Ras-related protein Rab-27A Ras-related protein Rab-3 Ras-related protein Rab-3 Ras-related protein Rab-4B Ras-related protein Rab-5C Ras-related protein Rab-7a Ras-related protein Rap-2 Ras-related protein Rap-2 Renin receptor Rho GTPase activating protein 45 Rho GTPase activating protein 9 Rho-associated protein kinase Ribonuclease T2 S100 calcium binding protein P Secretory carrier-associated membrane protein Serine/threonine-protein kinase 11-interacting protein Serine/threonine-protein phosphatase CPPED1 Serpin B10 Serpin B6 Serpin domain-containing protein Serpin family A member 3 Serpin family B member 12 Serpin family B member 1 Sialidase-1 Signal recognition particle 14 kDa protein Small VCP interacting protein Solute carrier family 15 member 4 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 5 Solute carrier organic anion transporter family member Sorbin and SH3 domain containing 2 Spectrin alpha, non-erythrocytic 1 Sphingolipid delta(4)-desaturase DES1 Starch binding domain 1 Stomatin Sulfhydryl oxidase Surfeit locus protein 4 Sushi domain-containing protein Synaptogyrin 1 Synaptosomal-associated protein 29 Synaptosomal-associated protein T-complex protein 1 subunit beta T-complex protein 1 subunit theta TBC1 domain family member 10C TNF alpha induced protein 6 TNF receptor superfamily member 1B TYRO protein tyrosine kinase-binding protein Target of myb1 membrane trafficking protein Tetraspanin Tetraspanin Tetraspanin Thioredoxin domain-containing protein Toll interacting protein Toll like receptor adaptor molecule 2 Toll-like receptor 2 Trafficking protein particle complex subunit Transcobalamin-like C-terminal domain-containing protein Transforming protein RhoA Transient receptor potential cation channel subfamily M member 2 Transitional endoplasmic reticulum ATPase Transmembrane BAX inhibitor motif containing 1 Transmembrane channel-like protein Transmembrane protein 179B Transmembrane protein 63A Transthyretin Tubulin beta chain Tubulin beta chain Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type UPAR/Ly6 domain-containing protein UPAR/Ly6 domain-containing protein Ubiquitin protein ligase E3 component n-recognin 4 Ubiquitin-like modifier-activating enzyme ATG7 Unc-13 homolog D Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Urokinase-type plasminogen activator V-type proton ATPase proteolipid subunit V-type proton ATPase subunit D V-type proton ATPase subunit a V-type proton ATPase subunit a VPS35 endosomal protein-sorting factor-like Vesicle amine transport 1 Vesicle-associated membrane protein 8 Vesicle-associated membrane protein-associated protein A Vinculin Voltage-gated hydrogen channel 1 Voltage-gated potassium channel subunit beta-1 X-ray repair cross complementing 5 X-ray repair cross complementing 6 acid phosphatase beta-mannosidase bis(5'-adenosyl)-triphosphatase cathepsin X deoxyribose-phosphate aldolase folate gamma-glutamyl hydrolase glycogenin glucosyltransferase heme oxygenase (biliverdin-producing) hexokinase long-chain-fatty-acid--CoA ligase non-specific serine/threonine protein kinase protein-tyrosine-phosphatase protein-tyrosine-phosphatase protein-tyrosine-phosphatase small monomeric GTPase small monomeric GTPase small monomeric GTPase thioredoxin-dependent peroxiredoxin trypsin	A0A1K0GGH0 A0A1S7J0A8 A0A8I3MB16 A0A8I3MC47 A0A8I3MDD5 A0A8I3MEA7 A0A8I3MEB5 A0A8I3MEX4 A0A8I3MF83 A0A8I3MFY4 A0A8I3MGN1 A0A8I3MGS3 A0A8I3MH42 A0A8I3MH54 A0A8I3MHW7 A0A8I3MHY1 A0A8I3MIF9 A0A8I3MJD4 A0A8I3MJP4 A0A8I3MK65 A0A8I3MKQ5 A0A8I3MLA2 A0A8I3MLE4 A0A8I3MLF7 A0A8I3MLR7 A0A8I3MMC4 A0A8I3MMP6 A0A8I3MN42 A0A8I3MN73 A0A8I3MNI1 A0A8I3MNR2 A0A8I3MP74 A0A8I3MQ69 A0A8I3MQC8 A0A8I3MQE5 A0A8I3MQK6 A0A8I3MQM8 A0A8I3MR78 A0A8I3MR81 A0A8I3MRC6 A0A8I3MRI6 A0A8I3MS83 A0A8I3MSC7 A0A8I3MSD7 A0A8I3MSE1 A0A8I3MSG1 A0A8I3MSJ8 A0A8I3MT07 A0A8I3MT53 A0A8I3MTF3 A0A8I3MTH4 A0A8I3MTX9 A0A8I3MUM3 A0A8I3MUZ6 A0A8I3MVB2 A0A8I3MVN4 A0A8I3MXC2 A0A8I3MXF6 A0A8I3MXX8 A0A8I3MY05 A0A8I3MY15 A0A8I3MYD5 A0A8I3MYE2 A0A8I3MYT7 A0A8I3MYY5 A0A8I3MZE8 A0A8I3MZT8 A0A8I3N083 A0A8I3N153 A0A8I3N1I2 A0A8I3N2C3 A0A8I3N2H6 A0A8I3N2Q2 A0A8I3N3H0 A0A8I3N3J7 A0A8I3N3K9 A0A8I3N3S4 A0A8I3N3T0 A0A8I3N466 A0A8I3N4H6 A0A8I3N518 A0A8I3N580 A0A8I3N5F1 A0A8I3N5K8 A0A8I3N5Z6 A0A8I3N6A8 A0A8I3N6N0 A0A8I3N6P9 A0A8I3N6Z5 A0A8I3N709 A0A8I3N7C0 A0A8I3N7F9 A0A8I3N7P9 A0A8I3N7Q3 A0A8I3N7S1 A0A8I3N7Y9 A0A8I3N8F9 A0A8I3N8T4 A0A8I3N9G3 A0A8I3N9K2 A0A8I3N9K7 A0A8I3N9V3 A0A8I3NAE2 A0A8I3NAI4 A0A8I3NAP3 A0A8I3NBB4 A0A8I3NBJ3 A0A8I3NBV6 A0A8I3NCT5 A0A8I3NDA5 A0A8I3NDF9 A0A8I3NDU0 A0A8I3NDZ2 A0A8I3NE51 A0A8I3NEJ3 A0A8I3NEU6 A0A8I3NFA2 A0A8I3NFB2 A0A8I3NFK0 A0A8I3NFM6 A0A8I3NFP5 A0A8I3NG14 A0A8I3NG24 A0A8I3NGT3 A0A8I3NGU2 A0A8I3NH32 A0A8I3NH42 A0A8I3NH46 A0A8I3NH98 A0A8I3NHX4 A0A8I3NHY9 A0A8I3NIB1 A0A8I3NIC8 A0A8I3NII5 A0A8I3NIM8 A0A8I3NIT3 A0A8I3NJ07 A0A8I3NK04 A0A8I3NKK7 A0A8I3NKR0 A0A8I3NL10 A0A8I3NLF4 A0A8I3NLW8 A0A8I3NLY0 A0A8I3NMM6 A0A8I3NMR3 A0A8I3NMT6 A0A8I3NMY9 A0A8I3NN43 A0A8I3NN65 A0A8I3NNG3 A0A8I3NNU1 A0A8I3NNW3 A0A8I3NP54 A0A8I3NP58 A0A8I3NPX1 A0A8I3NQA0 A0A8I3NQC1 A0A8I3NQX3 A0A8I3NR35 A0A8I3NR39 A0A8I3NRG2 A0A8I3NS26 A0A8I3NS45 A0A8I3NS51 A0A8I3NSU2 A0A8I3NT24 A0A8I3NT46 A0A8I3NTN1 A0A8I3NUD9 A0A8I3NUH8 A0A8I3NUL4 A0A8I3NUW9 A0A8I3NUX4 A0A8I3NV00 A0A8I3NV28 A0A8I3NV46 A0A8I3NVI8 A0A8I3NVN8 A0A8I3NVY9 A0A8I3NVZ2 A0A8I3NW54 A0A8I3NWA9 A0A8I3NWF7 A0A8I3NWQ3 A0A8I3NWY6 A0A8I3NXK9 A0A8I3NY48 A0A8I3NY55 A0A8I3NYF9 A0A8I3NYH1 A0A8I3NZ71 A0A8I3NZE3 A0A8I3NZH2 A0A8I3NZI2 A0A8I3NZP6 A0A8I3NZQ2 A0A8I3P0C9 A0A8I3P0M0 A0A8I3P0M4 A0A8I3P0N3 A0A8I3P1P3 A0A8I3P212 A0A8I3P230 A0A8I3P268 A0A8I3P2G0 A0A8I3P313 A0A8I3P3M6 A0A8I3P3N3 A0A8I3P478 A0A8I3P4F9 A0A8I3P4R2 A0A8I3P4U9 A0A8I3P528 A0A8I3P598 A0A8I3P626 A0A8I3P6A5 A0A8I3P6E2 A0A8I3P737 A0A8I3P7A7 A0A8I3P7P5 A0A8I3P836 A0A8I3P8U9 A0A8I3P8X9 A0A8I3P949 A0A8I3P9G9 A0A8I3P9U6 A0A8I3PAV8 A0A8I3PAY1 A0A8I3PAY5 A0A8I3PB92 A0A8I3PBB2 A0A8I3PBR6 A0A8I3PBS1 A0A8I3PC89 A0A8I3PCE5 A0A8I3PCF8 A0A8I3PCG1 A0A8I3PCG6 A0A8I3PCH7 A0A8I3PCP1 A0A8I3PD14 A0A8I3PD99 A0A8I3PDI3 A0A8I3PDN5 A0A8I3PDP4 A0A8I3PDV0 A0A8I3PDX5 A0A8I3PE71 A0A8I3PF55 A0A8I3PFD2 A0A8I3PGJ4 A0A8I3PGP9 A0A8I3PH48 A0A8I3PHA3 A0A8I3PHE3 A0A8I3PHH6 A0A8I3PHK5 A0A8I3PHN0 A0A8I3PI36 A0A8I3PI60 A0A8I3PII6 A0A8I3PIK8 A0A8I3PIY0 A0A8I3PJ87 A0A8I3PJ90 A0A8I3PJI1 A0A8I3PJZ4 A0A8I3PK00 A0A8I3PK26 A0A8I3PKH4 A0A8I3PKQ3 A0A8I3PLJ3 A0A8I3PMB7 A0A8I3PMF9 A0A8I3PMK1 A0A8I3PMT8 A0A8I3PN84 A0A8I3PNE3 A0A8I3PNK7 A0A8I3PNW5 A0A8I3PP24 A0A8I3PP92 A0A8I3PPE1 A0A8I3PPW7 A0A8I3PPY6 A0A8I3PQY3 A0A8I3PRM5 A0A8I3PSC3 A0A8I3PSP7 A0A8I3PSY9 A0A8I3PT92 A0A8I3PTV1 A0A8I3PTW0 A0A8I3PU34 A0A8I3PU36 A0A8I3PUF0 A0A8I3PUK3 A0A8I3PUM8 A0A8I3PUQ2 A0A8I3PV33 A0A8I3PV90 A0A8I3PVV6 A0A8I3PWC6 A0A8I3PWN4 A0A8I3PWS3 A0A8I3PXA4 A0A8I3PXH7 A0A8I3PXS2 A0A8I3PYZ5 A0A8I3PZ81 A0A8I3PZE0 A0A8I3PZH5 A0A8I3PZJ7 A0A8I3PZP0 A0A8I3PZT2 A0A8I3PZU6 A0A8I3Q020 A0A8I3Q024 A0A8I3Q0M4 A0A8I3Q165 A0A8I3Q1F4 A0A8I3Q2F2 A0A8I3Q3G7 A0A8I3Q3M9 A0A8I3Q466 A0A8I3Q4A0 A0A8I3Q4B1 A0A8I3Q4C7 A0A8I3Q4Q6 A0A8I3Q590 A0A8I3Q5B6 A0A8I3Q5B7 A0A8I3Q5R6 A0A8I3Q7R1 A0A8I3Q7W6 A0A8I3Q9B0 A0A8I3Q9Y4 A0A8I3QA46 A0A8I3QAA2 A0A8I3QAL4 A0A8I3QAR9 A0A8I3QBX8 A0A8I3QC57 A0A8I3QCP6 A0A8I3QCT3 A0A8I3QCU8 A0A8I3QHH1 A0A8I3QNM5 A0A8I3QNP3 A0A8I3QQ00 A0A8I3QRM6 A0A8I3QSK6 A0A8I3QV78 A0A8I3QYQ3 A0A8I3RQ73 A0A8I3RQ75 A0A8I3RQL9 A0A8I3RRR2 A0A8I3RRW0 A0A8I3RS37 A0A8I3RS62 A0A8I3RSP2 A0A8I3RSZ1 A0A8I3RT77 A0A8I3RTC9 A0A8I3RTE8 A0A8I3RTP3 A0A8I3RTV0 A0A8I3RU18 A0A8I3RUF3 A0A8I3RUF5 A0A8I3RUU8 A0A8I3RV44 A0A8I3RV50 A0A8I3RV84 A0A8I3RVF3 A0A8I3RVH7 A0A8I3RWI5 A0A8I3RWL6 A0A8I3RXI3 A0A8I3RXW5 A0A8I3RY39 A0A8I3RY80 A0A8I3RYQ6 A0A8I3RYZ8 A0A8I3RZ86 A0A8I3RZ95 A0A8I3S046 A0A8I3S0A6 A0A8I3S0E0 A0A8I3S0K7 A0A8I3S0M3 A0A8I3S0N5 A0A8I3S0Q3 A0A8I3S140 A0A8I3S1D9 A0A8I3S1K5 A0A8I3S1Q9 A0A8I3S1T6 A0A8I3S2M3 A0A8I3S2X1 A0A8I3S309 A0A8I3S5V2 A0A8I3S5W6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S6W0 A0A8I3S705 A0A8I3S758 A0A8I3S7C1 A0A8I3S7N5 A0A8I3S8N4 A0A8I3S972 A0A8I3S9F9 A0A8I3SA30 A0A8I3SA57 A0A8I3SAT0 A0A8I3SC19 A0A8I3SCF8 A1ILJ0 A7E3K7 A8QWU1 B1H0W0 B4YY03 E2RP87 F1PQS8 F1PZA1 F2Z4P4 F5C3N2 O02812 O97492 P18067 P38486 P51147 P61017 P62999 P81709 Q0X0E5 Q1HE58 Q2Q423 Q32KH5 Q32KI4 Q4LAL9 Q50KA8 Q53VB8 Q6F3J0 Q6TEQ7 Q6TN20 Q6YKA4 Q7YQC6 Q8MJD1 Q95MP7 Q9TRY9 Q9TSX8 Q9TTY1	607076 A1BG ABCA13 ACAA1 ACLY ACP3 ACTR10 ACTR1B ACTR2 ADAM10 ADAM8 ADGRE3 ADGRE5 ADGRG3 AGA AGL AGPAT2 AHSG ALAD ALDH3B1 ALDOA ALDOC ALOX5 AMPD3 ANO6 ANPEP ANX2 ANXA2 AP1M1 AP2A2 APAF1 APEH APRT ARG1 ARHGAP45 ARHGAP9 ARL8A ARMC8 ARPC5 ARSA ARSB ASAH1 ATAD3A ATG7 ATP11A ATP11B ATP6AP2 ATP6V0A1 ATP6V0C ATP6V1D ATP8A1 ATP8B4 B2M B4GALT1 BIN2 BPI BRI3 BST1 BST2 C12H6orf120 C1orf35 C3 C3AR1 C5AR1 C5BR CAB39 CALML5 CAMP CAND1 CAP1 CAPN1 CAT CCT2 CCT8 CD14 CD177 CD36 CD44 CD47 CD53 CD55 CD58 CD59 CD63 CD68 CD93 CDA CDK13 CEACAM1 CEACAM20 CEP290 CFD CFP CHI3L1 CHRNB4 CI-MPR/IGF2R CKAP4 CLEC4D CLEC5A CMTM6 CNN2 COMMD9 COPB1 COTL1 CPNE3 CPPED1 CRACR2A CREG1 CRISPLD2 CSBP1 CSBP2 CSNK2B CSTB CTSA CTSB CTSC CTSD CTSG CTSH CTSS CTSZ CXCR2 CYB5R3 CYBA CYBB CYFIP1 DDOST DDX3X DEGS1 DERA DGAT1 DIA1 DIAPH1 DLA-12 DLA-79 DLA88 DNAJC13 DNAJC3 DNAJC5 DNASE1L1 DOCK2 DOK3 DPP7 DSG1 DSN1 DSP DYNC1H1 DYNC1LI1 DYNLL1 DYNLT1 EEF1A1 EEF2 ELA2 ELANE ENPP4 EPX ERP44 FAF2 FCER1G FCGR2B FCGR3A FCN2 FGL2 FGR FPR2 FRK FRMPD3 FTH FTH1 FTL FUCA1 FUCA2 GAA GALNS GCA GDI2 GGH GHDC GLA GLB1 GLIPR1 GLNA2 GLNA3 GM2A GMFG GNS GOLGA7 GPI GPR84 GRN GSDMD GSN GSTP1 GUSB GYG1 HEBP2 HEXB HGSNAT HK3 HMGB1 HMOX2 HPSE HSP90AA1 HSP90AB1 HSPA1 HUWE1 HVCN1 Hsp70 IDH1 IGF2R ILF2 IMPDH IMPDH1 IMPDH2 IQGAP2 IST1 ITGAD ITGAL ITGAM ITGAV ITGB2 JUP KCMF1 KCNAB2 KPNB1 LAIR1 LAMP1 LAMP2 LAMTOR1 LAMTOR2 LAMTOR3 LCN2 LGALS3 LOC100685620 LOC100686511 LOC102152131 LOC102155828 LOC102155967 LOC119865338 LOC119868972 LOC119876012 LOC119876868 LOC119881359 LOC119881386 LOC476396 LOC476816 LOC478984 LOC484306 LOC484309 LOC484314 LOC484343 LOC490269 LOC607182 LOC607874 LOC609402 LOC609800 LOC611446 LPCAT1 LRG1 LRRC7 LTA4H LTF MAGT1 MAN2B1 MANBA MAPK1 MAPK14 MCEMP1 MGAM MGST1 MIF MLEC MME MMP25 MMP8 MMP9 MNDA MOSPD2 MPO MVP NAPRT NBEAL2 NCKAP1L NCSTN NDUFC2 NEU1 NFAM1 NFASC NFKB1 NHLRC3 NIT2 NM23B NME2 NRAS Nox2 OLFM4 OLR1 ORMDL3 OSCAR OSTF1 P2RX1 PA2G4 PADI2 PAFAH1B2 PDAP1 PDXK PECAM1 PFKL PGAM1 PGLYRP1 PGM2 PGRMC1 PIGR PKP1 PLAC8B PLAU PLD1 PLEKHO2 PNP PPBP PPIA PRCP PRDX4 PRDX6 PRG3 PRKCD PRSS2 PSAP PSEN1 PSMA2 PSMA5 PSMB1 PSMB7 PSMC2 PSMC3 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PTAFR PTGES2 PTPN6 PTPRB PTPRC PTPRJ PTX3 PYCARD PYGB PYGL QPCT QSOX1 RAB10 RAB18 RAB24 RAB27A RAB37 RAB3A RAB3D RAB44 RAB4B RAB5B RAB5C RAB7 RAB7A RAB9B RAC1 RAP1A RAP1B RAP2B RAP2C RETN RHOA RHOF RHOG RNASET2 ROCK1 S100A12 S100A9 S100P SCAMP1 SDCBP SELL SERPINA1 SERPINA3 SERPINB1 SERPINB10 SERPINB12 SERPINB6 SIGLEC11 SIRPA SLC11A1 SLC15A4 SLC27A2 SLC2A3 SLC2A5 SLC44A2 SLCO4C1 SLPI SNAP23 SNAP25 SNAP29 SORBS2 SPTAN1 SRP14 STBD1 STK10 STK11IP STOM SURF4 SVIP SYNGR1 TBC1D10C TCIRG1 TCN1 TICAM2 TIMP2 TLR2 TMBIM1 TMC6 TMEM179B TMEM30A TMEM63A TNFAIP6 TNFRSF1B TOLLIP TOM1 TRAPPC1 TRPM2 TSPAN14 TTR TUBB TUBB4B TXNDC5 TYROBP UBR4 UNC13D VAMP8 VAPA VAT1 VCL VCP VNN1 VPS35L XRCC5 XRCC6 YPEL YPEL5 arsb ckpi	Canis familiaris (dog)
Synthesis, secretion, and deacylation of Ghrelin	1-alkyl-2-acetylglycerophosphocholine esterase Appetite-regulating hormone Carboxylic ester hydrolase Glucagon Insulin-like growth factor I Insulin Leptin Membrane bound O-acyltransferase domain containing 4 Neuroendocrine convertase 1 Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin Uncharacterized protein	A0A8I3NP76 A0A8I3PBA0 A0A8I3PYH6 A0A8I3QXE0 A0A8I3RR59 A0A8I3RXD7 A0A8I3S964 P01321 P33711 P33712 P61008 P67811 P83362 Q28250 Q9BEF8	BCHE GCG GH GH1 GHRL IGF1 IGFIA INS LEP MBOAT4 MTLRP PCSK1 PLA2G7 SEC11A SEC11L1 SPC12 SPC18 SPC22 SPC25 SPCS1 SPCS2 SPCS3	Canis familiaris (dog)	G58161NS
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C delta 4 Phospholipase C zeta 1 Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A8I3MH68 A0A8I3MSQ7 A0A8I3MYA9 A0A8I3N810 A0A8I3NFE2 A0A8I3NWQ5 A0A8I3NY96 A0A8I3NZG2 A0A8I3PAP4 A0A8I3PAT0 A0A8I3PB87 A0A8I3PC05 A0A8I3PFD9 A0A8I3PLP7 A0A8I3PN52 A0A8I3PQK7 A0A8I3Q2Q7 A0A8I3Q4W3 A0A8I3Q7I7 A0A8I3Q9F2 A0A8I3QSE4 A0A8I3S2X3 A0A8I3S6D4 A0A8I3S7X1 A0A8I3SCI7 P60483	CALM2 INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC MMAC1 OCRL PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCZ1 PLD4 PTEN SHIP2 SYNJ1	Canis familiaris (dog)
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 5'-3' exonuclease PLD3 Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Phospholipase Phospholipase Phospholipid phosphatase 4 Protein kinase C delta type Protein kinase C epsilon type T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phospholipase A2	A0A5F4C2B1 A0A8I3MFY1 A0A8I3MMY6 A0A8I3MQR0 A0A8I3MV98 A0A8I3N971 A0A8I3NEM6 A0A8I3NWR3 A0A8I3NYY2 A0A8I3NZG2 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PAT0 A0A8I3PCM7 A0A8I3PD67 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PWT0 A0A8I3PWT3 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3PZJ7 A0A8I3Q258 A0A8I3Q590 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3QHH1 A0A8I3QQ00 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S3N2 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 A0A8I3SCI7 E2RP87	CD247 CD3G FCGR1A FCGR2B FCGR3A LOC478984 PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD PRKCE SYK	Canis familiaris (dog)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk BCAR1 scaffold protein, Cas family member CRK like proto-oncogene, adaptor protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B RAS p21 protein activator 1 Rap guanine nucleotide exchange factor 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N1K5 A0A8I3N488 A0A8I3N971 A0A8I3N974 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NGQ0 A0A8I3NID0 A0A8I3P5F5 A0A8I3PDZ1 A0A8I3PMT9 A0A8I3PN08 A0A8I3PSA1 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3RV66 A0A8I3RVE7 A0A8I3RXB9 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S602 A0A8I3S8J3 A0A8I3SBF9 A0A8I3SCI7 Q6Q7I7	BCAR1 CRK CRKL GRB2 GRB7 HRAS KRAS NCK1 NCK2 NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PTPN11 RAPGEF1 RASA1 SOS1 SRC STAT1 STAT3 STAT5A STAT5B STAT6	Canis familiaris (dog)
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Beta-2-microglobulin C-type lectin domain-containing protein C-type lectin domain-containing protein GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Immunoglobulin subtype domain-containing protein Lymphocyte cytosolic protein 2 NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 TYRO protein tyrosine kinase-binding protein Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3MDD5 A0A8I3MGV8 A0A8I3MMK3 A0A8I3N971 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NUU1 A0A8I3NVH5 A0A8I3NZG2 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P6Q8 A0A8I3P7Z3 A0A8I3PNL2 A0A8I3PNS2 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PWV8 A0A8I3PXH7 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3S3N2 A0A8I3SCI7 P62999 Q38HS3	B2M BTK CD94 FYN GRAP2 GRB2 HRAS KLRD1 KLRK1 KRAS LAT LCK LCP2 LOC119863908 LOC119866326 NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PLCG1 PLCG2 RAC1 SHC1 SOS1 SYK TYROBP VAV2 VAV3	Canis familiaris (dog)
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma CD101 molecule Cytoplasmic protein FYN binding protein 1 GRB2 related adaptor protein 2 Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Lymphocyte cytosolic protein 2 MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 P21 (RAC1) activated kinase 3 Phosphoinositide phospholipase C T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A8I3MED5 A0A8I3MFY1 A0A8I3MGV8 A0A8I3MJ11 A0A8I3MKK6 A0A8I3MMK2 A0A8I3MMK3 A0A8I3MMZ1 A0A8I3MV98 A0A8I3MZ69 A0A8I3NAC6 A0A8I3NMF7 A0A8I3NTK0 A0A8I3NZG2 A0A8I3P4A1 A0A8I3P564 A0A8I3P6Q8 A0A8I3P8U2 A0A8I3PAB8 A0A8I3PNN9 A0A8I3Q5D2 A0A8I3QD39 A0A8I3S023 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S602 A0A8I3SCI7 P27597 P33705	CD101 CD247 CD3D CD3E CD3G CD4 DLA-DQA1 DLA-DRA FYB1 GRAP2 HLA-DQB2 ITK LAT LCK LCP2 NCK1 PAK1 PAK2 PAK3 PLCG1 PLCG2 TRAV29DV5 ZAP70	Canis familiaris (dog)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 KGF PLCG1	Canis familiaris (dog)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 PLCG1	Canis familiaris (dog)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 KL PLCG1	Canis familiaris (dog)
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin Appetite-regulating hormone Arginine vasopressin B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 Cholecystokinin Coagulation factor II thrombin receptor like 2 Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 Free fatty acid receptor 1 Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 4 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 143 G protein-coupled receptor 17 G protein-coupled receptor 68 G protein-coupled receptor kinase G-protein coupled receptor family C group 6 member A G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Glucagon Glutamate metabotropic receptor 1 Glutamate metabotropic receptor 5 Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H1 receptor Hypocretin neuropeptide precursor KISS1 receptor Kininogen 1 Kisspeptin Leukotriene B4 receptor 2 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 5 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanopsin Motilin receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Neuromedin B receptor Neuromedin B Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-K receptor Neuromedin-K Neuromedin-S Neuromedin-U-25 Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor 1 Neuropeptide S Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y receptor family member 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-activating factor receptor Pro-MCH Progonadoliberin Prokineticin 1 Prokineticin 2 Prokineticin receptor 1 Promotilin Prostaglandin E2 receptor EP1 subtype Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Prothrombin Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide Regulator of G protein signaling 13 Regulator of G protein signaling 17 Regulator of G protein signaling 18 Regulator of G protein signaling 19 Regulator of G protein signaling 21 Regulator of G protein signaling 3 Regulator of G protein signaling 5 Regulator of G protein signaling like 1 Regulator of G-protein signaling 16 Regulator of G-protein signaling 1 Regulator of G-protein signaling 2 Regulator of G-protein signaling 4 Rho guanine nucleotide exchange factor 25 Substance-K receptor Substance-P receptor Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Urotensin 2B Urotensin-2 receptor Urotensin-2 Vasopressin V1a receptor Vasopressin V1b receptor non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3M9P4 A0A8I3MBK3 A0A8I3ME07 A0A8I3MH22 A0A8I3MHA7 A0A8I3MIG1 A0A8I3MKF9 A0A8I3MKX3 A0A8I3MM75 A0A8I3MM87 A0A8I3MN59 A0A8I3MNZ2 A0A8I3MPF9 A0A8I3MPW0 A0A8I3MQB9 A0A8I3MRG9 A0A8I3MRI6 A0A8I3MSX9 A0A8I3MTW1 A0A8I3MU21 A0A8I3MYE3 A0A8I3MZ62 A0A8I3N081 A0A8I3N0R9 A0A8I3N125 A0A8I3N190 A0A8I3N2K3 A0A8I3N4T4 A0A8I3N4Y4 A0A8I3N5K9 A0A8I3N7G1 A0A8I3N8M9 A0A8I3N971 A0A8I3N9Q6 A0A8I3NAP0 A0A8I3NCM2 A0A8I3NE44 A0A8I3NE91 A0A8I3NEI6 A0A8I3NEL6 A0A8I3NFC7 A0A8I3NFE6 A0A8I3NFL3 A0A8I3NFV9 A0A8I3NHY0 A0A8I3NK63 A0A8I3NKP7 A0A8I3NL60 A0A8I3NN89 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NPT8 A0A8I3NPX3 A0A8I3NQV1 A0A8I3NT15 A0A8I3NTE8 A0A8I3NX67 A0A8I3NZX3 A0A8I3P1U0 A0A8I3P519 A0A8I3P5C5 A0A8I3P7Z3 A0A8I3P9H6 A0A8I3PBE4 A0A8I3PBK9 A0A8I3PC67 A0A8I3PCA6 A0A8I3PCK7 A0A8I3PED5 A0A8I3PEX2 A0A8I3PFJ2 A0A8I3PH67 A0A8I3PJF2 A0A8I3PJM2 A0A8I3PL97 A0A8I3PLY8 A0A8I3PM36 A0A8I3PM57 A0A8I3PMD7 A0A8I3PN52 A0A8I3PPA3 A0A8I3PQK7 A0A8I3PS75 A0A8I3PTJ5 A0A8I3PTY7 A0A8I3PUT1 A0A8I3PV05 A0A8I3PVE7 A0A8I3PVZ2 A0A8I3PW94 A0A8I3PWB5 A0A8I3PWE8 A0A8I3PYW9 A0A8I3Q0U9 A0A8I3Q141 A0A8I3Q2R9 A0A8I3Q3G9 A0A8I3Q3M6 A0A8I3Q4W3 A0A8I3Q5H2 A0A8I3Q9F7 A0A8I3QB92 A0A8I3QBR1 A0A8I3QEQ9 A0A8I3QXE0 A0A8I3RQW9 A0A8I3RQZ1 A0A8I3RR88 A0A8I3RSX8 A0A8I3RTK7 A0A8I3RV82 A0A8I3RVA9 A0A8I3RX12 A0A8I3RXY8 A0A8I3RY80 A0A8I3RYN2 A0A8I3RZH5 A0A8I3S015 A0A8I3S0K5 A0A8I3S0V2 A0A8I3S0Y6 A0A8I3S1Q6 A0A8I3S2W1 A0A8I3S3N2 A0A8I3S3Q7 A0A8I3S4W4 A0A8I3S5G1 A0A8I3S6D4 A0A8I3S7S8 A0A8I3SAA7 A0A8I3SBJ6 A2SXS6 A5HKU8 B2NIZ6 E2R3W5 J9NWZ9 O46635 O97564 P01353 P10673 P12064 P13206 P30552 P62872 P63210 P79147 Q28294 Q45FN0 Q5DUB2 Q5DUB3 Q5J7U3 Q5XX73 Q5XXR2 Q8MIP6 Q9BDQ4 Q9BDQ5 Q9BEF8 Q9BGL8 Q9GLF6 Q9TUP7	5-HTR2A ADRA1A ADRA1B ADRA1D AGT AGTR1 ANXA1 APP ARHGEF25 AVP AVPR1A AVPR1B BDKRB1 BDKRB2 BRS3 BTK Bdkrb2 CASR CCK CCKBR CCL23 CHRM1 CHRM3 CHRM5 CYSLTR1 CYSLTR2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FFAR1 FFAR2 FFAR4 FPR2 GAS GAST GCG GCGR GHRL GHSR GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 GNRH1 GNRHR GPR132 GPR143 GPR17 GPR39 GPR68 GPRC6A GRK2 GRM1 GRM5 GRP GRPR HCRT HCRTR1 HCRTR2 HRH1 HTR2A HTR2B HTR2C KALRN KISS1R KNG1 Kiss1 LOC100856339 LOC116183080 LOC119863873 LOC119865171 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LTB4R2 MCH MCHR1 MCHR2 MLN MLNR MTLR MTLRP NMB NMBR NMS NMU NMUR1 NMUR2 NPFFR1 NPFFR2 NPS NPSR1 NTS NTSR1 NTSR2 OPN4 OX OXT OXTR P2RY1 P2RY10 P2RY11 P2RY2 P2RY6 PIK3CA PIK3R1 PIK3R2 PLCB1 PLCB2 PLCB3 PLCB4 PMCH PPOX PROK1 PROK2 PROKR1 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL1 TAC1 TACR1 TACR2 TACR3 TBXA2R TRH TRHR UTS2B UTS2R XCR1	Canis familiaris (dog)
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Vav guanine nucleotide exchange factor 1 cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3N974 A0A8I3NA65 A0A8I3NBM3 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PBB4 A0A8I3PMT9 A0A8I3PRW9 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q4Y8 A0A8I3Q525 A0A8I3RVE7 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3N2 P48749 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB IL3 IL5 IL5RA JAK2 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ	Canis familiaris (dog)
GP1b-IX-V activation signalling	14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase von Willebrand factor von Willebrand factor	A0A8I3PZA0 A0A8I3Q4Y8 A0A8I3SBF9 A0A8I3SCK0 Q28295	F8VWF RAF1 SRC VWF YWHAZ	Canis familiaris (dog)
Downstream TCR signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 BCL10 immune signaling adaptor Caspase recruitment domain family member 11 Cullin 1 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme F-box and WD repeat domain containing 11 Ig-like domain-containing protein IkappaB kinase Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein kinase C RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha variable 29/delta variable 5 T cell receptor associated transmembrane adaptor 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ82 A0A8I3MKK6 A0A8I3MKL4 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MNA4 A0A8I3MNI0 A0A8I3MQX7 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV98 A0A8I3MZ69 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N7L6 A0A8I3N952 A0A8I3N971 A0A8I3N9G3 A0A8I3NAC6 A0A8I3NFB9 A0A8I3NH42 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NT57 A0A8I3NT75 A0A8I3NTK0 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NW81 A0A8I3NXK9 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4A1 A0A8I3P4Z1 A0A8I3P564 A0A8I3P6I7 A0A8I3P6M2 A0A8I3PAB8 A0A8I3PAP4 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PFI5 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PMA2 A0A8I3PR42 A0A8I3PWT3 A0A8I3PZT2 A0A8I3QV78 A0A8I3QYD0 A0A8I3RR14 A0A8I3RRK6 A0A8I3RRL7 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S023 A0A8I3S1Z6 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S3N2 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P27597 P33705 P60483 P63050 Q5W412 Q5W416 Q6F3J0	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CDC34 CHUK CUL1 DLA-DQA1 DLA-DRA FBXW11 HLA-DQB2 IKBKB IKBKG INPP5D LCK LOC100686569 LOC100687259 LOC119881719 LOC610717 MALT1 MAP3K7 MMAC1 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN RELA RIPK2 RPS27A SKP1 TAB2 TRAF6 TRAT1 TRAV29DV5 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2N	Canis familiaris (dog)
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily A member 4 ATP binding cassette subfamily A member 8 ATP binding cassette subfamily B member 1 ATP binding cassette subfamily B member 4 ATP binding cassette subfamily B member 5 ATP binding cassette subfamily B member 9 ATP binding cassette subfamily C member 10 ATP binding cassette subfamily C member 11 ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 ATP binding cassette subfamily C member 9 ATP binding cassette subfamily F member 1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Derlin Derlin Derlin E3 ubiquitin-protein ligase RNF Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein protein-synthesizing GTPase	A0A8I3MFR7 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV19 A0A8I3N0P1 A0A8I3N153 A0A8I3N165 A0A8I3N1B7 A0A8I3N1I8 A0A8I3N222 A0A8I3N2I4 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N6K4 A0A8I3N6T3 A0A8I3N6X7 A0A8I3N7G8 A0A8I3N952 A0A8I3N9B0 A0A8I3N9G3 A0A8I3NB03 A0A8I3NFB9 A0A8I3NH42 A0A8I3NKE8 A0A8I3NN65 A0A8I3NND5 A0A8I3NNJ9 A0A8I3NNW7 A0A8I3NP66 A0A8I3NPX1 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NV30 A0A8I3NVA4 A0A8I3NW81 A0A8I3NXK9 A0A8I3NXV6 A0A8I3NZK9 A0A8I3P6M2 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PGC3 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PM01 A0A8I3PMA2 A0A8I3PME6 A0A8I3PVZ3 A0A8I3PZT2 A0A8I3Q3Z7 A0A8I3Q7I5 A0A8I3QV78 A0A8I3QYD0 A0A8I3RRR7 A0A8I3RT39 A0A8I3RU74 A0A8I3RV68 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S0X8 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3SCV5 B8K1W7 P63050 Q5U820 Q5W412 Q5W416 Q6UR05	ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 Abcc4 CFTR DERL1 DERL2 DERL3 EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 KCNJ11 LOC100686569 LOC100687259 LOC610717 MRP1 OS9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RNF5 RPS27A SEL1L UBA52 UBB UBC UBCEP2 VCP	Canis familiaris (dog)
Ub-specific processing proteases	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ADRM1 26S proteasome ubiquitin receptor Androgen receptor Ataxin 7 Axin 2 Axin-1 Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cell division cycle 20 Cellular tumor antigen p53 Centriolar coiled-coil protein 110 Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DNA polymerase E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Farnesylated proteins-converting enzyme 2 Forkhead box O4 GATA binding protein 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Hypoxia-inducible factor 1-alpha Insulin degrading enzyme Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase Mitochondrial import receptor subunit TOM20 homolog Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein Mdm4 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RNA helicase Receptor interacting serine/threonine kinase 1 Ring finger protein 128 RuvB-like helicase SDS3 homolog, SIN3A corepressor complex component Signal transducing adaptor molecule 2 TATA-box binding protein associated factor 9b TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta receptor type-1 TNF receptor-associated factor 6 TNF receptor-associated factor Tankyrase 2 Transcription initiation factor TFIID subunit 10 Transcriptional adapter 3 Transcriptional adapter Transformation/transcription domain associated protein Translocase of outer mitochondrial membrane 70 USP domain-containing protein Ubiquitin B Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin specific peptidase 28 Ubiquitin specific peptidase 42 Ubiquitin thioesterase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat domain 20 WD repeat-containing protein 48 histone acetyltransferase peptidyl-tRNA hydrolase peptidylprolyl isomerase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A7R7V602 A0A8I3MC37 A0A8I3MCW5 A0A8I3MDM0 A0A8I3MDQ5 A0A8I3MFT9 A0A8I3MJQ1 A0A8I3MKL2 A0A8I3MKL4 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MPG9 A0A8I3MQC7 A0A8I3MR89 A0A8I3MRP8 A0A8I3MSL4 A0A8I3MU16 A0A8I3MUE2 A0A8I3MWJ0 A0A8I3MWQ7 A0A8I3MZA5 A0A8I3N0P1 A0A8I3N165 A0A8I3N2P0 A0A8I3N371 A0A8I3N3A0 A0A8I3N3R0 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N683 A0A8I3N6Q2 A0A8I3N7L6 A0A8I3N7R6 A0A8I3N952 A0A8I3N9G3 A0A8I3NA81 A0A8I3NAP2 A0A8I3NAV8 A0A8I3NBQ5 A0A8I3NDB6 A0A8I3NEM9 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGL0 A0A8I3NGV0 A0A8I3NH42 A0A8I3NH60 A0A8I3NHL8 A0A8I3NLI9 A0A8I3NM89 A0A8I3NMN1 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP66 A0A8I3NP69 A0A8I3NPX1 A0A8I3NR70 A0A8I3NRK8 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NUT4 A0A8I3NV88 A0A8I3NW63 A0A8I3NW81 A0A8I3NWA6 A0A8I3NXK9 A0A8I3NY77 A0A8I3NYC7 A0A8I3NYE9 A0A8I3NYK2 A0A8I3NZ86 A0A8I3P0Y8 A0A8I3P135 A0A8I3P2V4 A0A8I3P616 A0A8I3P6B7 A0A8I3P6G1 A0A8I3P6J5 A0A8I3P6M2 A0A8I3P738 A0A8I3P7J9 A0A8I3P9V4 A0A8I3PB52 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCC0 A0A8I3PCE5 A0A8I3PCI4 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PE84 A0A8I3PF55 A0A8I3PF76 A0A8I3PFL3 A0A8I3PG60 A0A8I3PGG8 A0A8I3PHC7 A0A8I3PI05 A0A8I3PJL4 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PLL0 A0A8I3PMA2 A0A8I3PMH0 A0A8I3PNU1 A0A8I3PQ44 A0A8I3PQ52 A0A8I3PQD9 A0A8I3PU69 A0A8I3PVR3 A0A8I3PW10 A0A8I3PWL6 A0A8I3PWM3 A0A8I3PWW2 A0A8I3PX43 A0A8I3PY49 A0A8I3PYV8 A0A8I3PZ26 A0A8I3PZ42 A0A8I3PZ96 A0A8I3PZT2 A0A8I3Q0K8 A0A8I3Q3S2 A0A8I3Q4M1 A0A8I3Q5J1 A0A8I3Q610 A0A8I3Q7Y0 A0A8I3Q883 A0A8I3QA55 A0A8I3QBV9 A0A8I3QCQ3 A0A8I3QV78 A0A8I3QYD0 A0A8I3RP35 A0A8I3RRR7 A0A8I3RS56 A0A8I3RSX0 A0A8I3RT18 A0A8I3RT39 A0A8I3RV68 A0A8I3RVA5 A0A8I3RWV3 A0A8I3RWY9 A0A8I3RXL5 A0A8I3RXS6 A0A8I3RXV3 A0A8I3RZ76 A0A8I3RZD9 A0A8I3RZF7 A0A8I3RZF8 A0A8I3RZP6 A0A8I3RZQ8 A0A8I3S1Z6 A0A8I3S2L7 A0A8I3S2R9 A0A8I3S3G6 A0A8I3S4J6 A0A8I3S4R5 A0A8I3S6C6 A0A8I3S6H8 A0A8I3S6Q5 A0A8I3S789 A0A8I3S792 A0A8I3S794 A0A8I3S7M5 A0A8I3S9E1 A0A8I3S9T4 A0A8I3SCL5 A1E2V0 D2YYC0 E2RK09 E7FIY6 H9GWB1 J9P6S8 O97863 P56950 P60483 P63050 Q5U820 Q5W412 Q5W416	ABCC7 ADRB2 ADRM1 AR ARRB1 ARRB2 ATXN7 AXIN1 AXIN2 BECN1 BIRC2 BIRC3 CCNA1 CCNA2 CCP110 CDC20 CDC25A CDK16 CFTR CLSPN CYLD FKBP8 FOXO4 GATA3 H2AC1 H2AC13 H2AC14 H2AC16 H2AC19 H2AC21 H2AC25 H2AC4 H2AC6 H2BC10 H2BC15 H2BC2 H2BC21 H2BC26 H2BC3 HGS HIF1A IDE IFIH1 IKBKG IL33 KAT2A KEAP1 LOC100686569 LOC100687259 LOC100688437 LOC119867694 LOC119867696 LOC119867718 LOC119868881 LOC119869165 LOC119869175 LOC119869178 LOC119869187 LOC119869258 LOC119874734 LOC482940 LOC610717 MAP3K7 MAT2B MDM2 MDM4 MMAC1 MUL1 MYC Madh3 NFKBIA OTUB1 POLB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN PTRH2 RCE1 RHOT1 RIPK1 RNF123 RNF128 RNF146 RPS27A RUVBL1 SIAH2 SMAD1 SMAD2 SMAD3 SMAD7 SMURF2 STAM2 SUDS3 TAB1 TADA2B TADA3 TAF10 TAF9B TGFBR1 TNKS TNKS2 TOMM20 TOMM70 TP53 TRAF2 TRAF6 TRRAP UBA52 UBB UBC UBCEP2 USP10 USP12 USP13 USP14 USP15 USP16 USP18 USP19 USP2 USP20 USP21 USP22 USP26 USP28 USP3 USP30 USP33 USP34 USP37 USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 VDAC1 VDAC2 VDAC3 WDR20 WDR48 p53	Canis familiaris (dog)
TNFR2 non-canonical NF-kB pathway	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand LIGHT Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor superfamily member 1B TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 13b Tumor necrosis factor (ligand) superfamily, member 12 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5 Tumor necrosis factor Uncharacterized protein Uncharacterized protein	A0A8I3MDM0 A0A8I3MEA7 A0A8I3MES0 A0A8I3MNI0 A0A8I3MQC7 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MWN3 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N952 A0A8I3N9G3 A0A8I3NGJ3 A0A8I3NH42 A0A8I3NLQ1 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP66 A0A8I3NPX1 A0A8I3NRP3 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NW81 A0A8I3NXK9 A0A8I3P6H0 A0A8I3P6M2 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PMA2 A0A8I3PTD2 A0A8I3PZM4 A0A8I3PZT2 A0A8I3QV78 A0A8I3RR83 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A1E2V0 J9JHM5 J9P2Z1 J9P753 O97626 P51742 Q5W412 Q5W416 Q5WR07	BIRC2 BIRC3 CD40 CD40L CD40LG LOC100686569 LOC100687259 LOC610717 LTA LTB LTBR MAP3K14 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 TNF TNFA TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF2 TNFSF5 TNLG1C TNLG1D TNLG7A TRAF2 TRAF3	Canis familiaris (dog)
Interleukin-1 signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase pellino homolog E3 ubiquitin-protein ligase pellino homolog IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Interleukin 1 receptor accessory protein Interleukin 1 receptor associated kinase 3 Interleukin 1 receptor type 1 Interleukin 1 receptor type 2 Interleukin-1 receptor antagonist protein Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Interleukin-1 Mitogen-activated protein kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase 7 Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Pellino E3 ubiquitin protein ligase family member 3 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RELA proto-oncogene, NF-kB subunit Ring-box 1 S-phase kinase-associated protein 1 Sequestosome 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Toll interacting protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A8I3MKL4 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3N0P1 A0A8I3N165 A0A8I3N2A1 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N5F6 A0A8I3N7L6 A0A8I3N952 A0A8I3N9G3 A0A8I3NBF5 A0A8I3NFB9 A0A8I3NH42 A0A8I3NHA9 A0A8I3NJ31 A0A8I3NMB6 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPR4 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NVB6 A0A8I3NW81 A0A8I3NXK9 A0A8I3NXW3 A0A8I3NZN1 A0A8I3P046 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4Z1 A0A8I3P6I7 A0A8I3P6M2 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PGC5 A0A8I3PJH9 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PLL0 A0A8I3PMA2 A0A8I3PN81 A0A8I3PV99 A0A8I3PZT2 A0A8I3Q059 A0A8I3Q209 A0A8I3QV78 A0A8I3QYD0 A0A8I3RRR7 A0A8I3RT39 A0A8I3RUU8 A0A8I3RXV3 A0A8I3RY59 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P63050 Q5W412 Q5W416 Q6F3J0 Q9BEH0	CHUK CUL1 IKBKB IKBKG IL1A IL1B IL1R1 IL1R2 IL1RAP IL1RN IRAK1 IRAK2 IRAK3 IRAK4 LOC100686569 LOC100687259 LOC119881719 LOC610717 MAP2K6 MAP3K3 MAP3K7 MYD88 NFKB1 NFKBIA PELI1 PELI2 PELI3 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RBX1 RELA RPS27A SKP1 SQSTM1 TAB1 TAB2 TAB3 TOLLIP TRAF6 UBA52 UBB UBC UBCEP2 UBE2N	Canis familiaris (dog)
Sphingolipid de novo biosynthesis	3-dehydrosphinganine reductase Broad substrate specificity ATP-binding cassette transporter ABCG2 Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Cytochrome b5 heme-binding domain-containing protein Delta 4-desaturase, sphingolipid 2 Fatty acid 2-hydroxylase Major facilitator superfamily domain containing 2B Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 ORM1-like protein ORM1-like protein ORM1-like protein SPNS lysolipid transporter 2, sphingosine-1-phosphate Serine palmitoyltransferase 1 Serine palmitoyltransferase long chain base subunit 2 Serine palmitoyltransferase long chain base subunit 3 Sphingolipid delta(4)-desaturase DES1 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Uncharacterized protein Uncharacterized protein	A0A8I3MDB1 A0A8I3MDX2 A0A8I3MH69 A0A8I3MTG4 A0A8I3MVV0 A0A8I3MZT5 A0A8I3N0C8 A0A8I3N1I8 A0A8I3N6A8 A0A8I3N8H8 A0A8I3NCL9 A0A8I3NE51 A0A8I3NF48 A0A8I3P1Y0 A0A8I3P1Z6 A0A8I3P4B7 A0A8I3PAM7 A0A8I3PG24 A0A8I3PM33 A0A8I3PMG7 A0A8I3PQ53 A0A8I3Q2P7 A0A8I3S0D0 A0A8I3S194 A0A8I3S6X3 A0A8I3S790 B3RFJ1 Q6UR05	ABCC1 ABCG2 Abcg2 CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CYB5B DEGS1 DEGS2 FA2H KDSR MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPNS2 SPTLC1 SPTLC2 SPTLC3 SPTSSA	Canis familiaris (dog)
Integrin signaling	3-phosphoinositide-dependent protein kinase 1 Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Fibronectin Focal adhesion kinase 1 Integrin beta Integrin subunit alpha 2b RAS guanyl releasing protein 2 RAS guanyl-releasing protein 1 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 SHC-transforming protein 1 Talin 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type small monomeric GTPase small monomeric GTPase von Willebrand factor von Willebrand factor	A0A8I3MQX7 A0A8I3N6K0 A0A8I3N737 A0A8I3NMY1 A0A8I3NUL4 A0A8I3NUU1 A0A8I3P3G0 A0A8I3P4Z0 A0A8I3PED8 A0A8I3PMU9 A0A8I3PW63 A0A8I3PWD7 A0A8I3PXV2 A0A8I3PZ28 A0A8I3Q868 A0A8I3RUF3 A0A8I3RVR5 A0A8I3SBF9 A0A8I3SCK0 Q28295	APBB1IP CSK F8VWF FN1 ITGA2B ITGB3 PDPK1 PTK2 PTPN1 RAP1A RAP1B RAPGEF3 RAPGEF4 RASGRP1 RASGRP2 SHC1 SRC SYK TLN1 VWF	Canis familiaris (dog)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 B7-1 protein CD19 molecule CD86 molecule EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor accessory protein Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Kit Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proline rich 5 RPTOR independent companion of MTOR complex 2 Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase Sgk1 Serine/threonine-protein kinase mTOR Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MAV6 A0A8I3MIK8 A0A8I3MJG3 A0A8I3MN72 A0A8I3MP09 A0A8I3MPF4 A0A8I3MQX7 A0A8I3MRL6 A0A8I3MT80 A0A8I3MX71 A0A8I3MZ71 A0A8I3MZG1 A0A8I3N0H9 A0A8I3N488 A0A8I3N5M3 A0A8I3N8T5 A0A8I3N971 A0A8I3N9M7 A0A8I3NA65 A0A8I3NAC6 A0A8I3NAN8 A0A8I3NEF4 A0A8I3NFQ7 A0A8I3NGY1 A0A8I3NH46 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NIT3 A0A8I3NKX5 A0A8I3NLT7 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVK5 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NWK3 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P2V4 A0A8I3P3M1 A0A8I3P3X1 A0A8I3P4L9 A0A8I3P519 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PKX6 A0A8I3PMT9 A0A8I3PN81 A0A8I3PR42 A0A8I3PT69 A0A8I3PV99 A0A8I3PWT3 A0A8I3Q059 A0A8I3Q1C3 A0A8I3Q209 A0A8I3Q314 A0A8I3Q525 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RR99 A0A8I3RRT3 A0A8I3RSF1 A0A8I3RTN7 A0A8I3RYJ5 A0A8I3S0I1 A0A8I3S0T0 A0A8I3S333 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 A0A8I3SBF9 E2REX2 J9P0B3 J9P3I7 J9P8K0 O97799 O97863 P62999 P79150 Q06220 Q20FD0 Q6Q7I7 Q7YR73 Q867B7 Q9TQX1	AILIM AREG BTC CD19 CD28 CD80 CD86 EGF EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GRB2 HBEGF HGF ICOS IL1RAP IL33 IRAK1 IRAK4 IRS1 IRS2 KGF KIT KITLG KL KLB LCK LOC100856339 MAPKAP1 MET MGF MLST8 MTOR MYD88 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRR5 PTPN11 RAC1 RAC2 RHOG RICTOR SGK1 SRC STRN TGFA TRAF6 TRAT1 VAV1	Canis familiaris (dog)
GPVI-mediated activation cascade	3-phosphoinositide-dependent protein kinase 1 C-type lectin domain-containing protein Cell division control protein 42 homolog High affinity immunoglobulin epsilon receptor subunit gamma Lymphocyte cytosolic protein 2 Megakaryocyte and platelet inhibitory receptor G6b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide phospholipase C Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Phosphoinositide-3-kinase regulatory subunit 6 Podoplanin Rac family small GTPase 2 Ras homolog family member B Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Transforming protein RhoA Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MGV8 A0A8I3MHV4 A0A8I3MMK3 A0A8I3MQX7 A0A8I3MY22 A0A8I3N060 A0A8I3N5M3 A0A8I3N971 A0A8I3NA65 A0A8I3NAC6 A0A8I3NC73 A0A8I3NEZ8 A0A8I3NH46 A0A8I3NHC2 A0A8I3NIT3 A0A8I3NZG2 A0A8I3P075 A0A8I3P3G0 A0A8I3P3X1 A0A8I3P519 A0A8I3PMT9 A0A8I3PUN0 A0A8I3PVV6 A0A8I3PWC6 A0A8I3PWT3 A0A8I3PY16 A0A8I3QSK6 A0A8I3S3N2 A0A8I3S601 P60952 P62999 Q95152	CDC42 CLEC1B FCER1G FYN GP40 GP6 LAT LCK LCP2 LOC100856339 LYN MPIG6B PDPK1 PDPN PIK3CA PIK3CB PIK3CG PIK3R1 PIK3R2 PIK3R5 PIK3R6 PLCG2 PTPN11 PTPN6 RAC1 RAC2 RHOA RHOB RHOG SYK VAV1 VAV2 VAV3	Canis familiaris (dog)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Solute carrier family 25 member 16 Solute carrier family 5 member 6	A0A8I3MUX5 A0A8I3MVX3 A0A8I3MY61 A0A8I3PCZ1 A0A8I3Q2U7 A0A8I3RQN4 A0A8I3S3J2 Q9TSX8	AASDHPPT FASN PANK4 PDZD11 SLC25A16 SLC25A42 SLC5A6 VNN1	Canis familiaris (dog)
Lewis blood group biosynthesis	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A8I3MCT3 A0A8I3NB27 A0A8I3NB67 A0A8I3NFY5 A0A8I3NLH2 A0A8I3NR40 A0A8I3NRD0 A0A8I3P0Y9 A0A8I3PNT8 A0A8I3PQF7 A0A8I3Q8H7 A0A8I3RVW4 A0A8I3S1H8 Q5TJE8 Q659L1	B3GALT2 B3GALT4 B3GALT5 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT5 FUT7 FUT9 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Canis familiaris (dog)	G39211DH G81971FM G83633HB G90387AM G98173LG
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4	Canis familiaris (dog)

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