GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **597** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Transcriptional activtion and repression of REL-68 target genes	High mobility group protein DSP1 Histone acetyltransferase GCN5 Histone deacetylase HDAC1 Nuclear factor NF-kappa-B p110 subunit Signal transducer and transcription activator Transcription factor Jra Transcription factor kayak, isoforms A/B/F	O76216 P18289 P21525 Q24151 Q24537 Q94517 Q94527	Dsp1 Fra Gcn5 HDAC1 Jra MARE Pcaf Rel Rpd3 Stat Stat92E jun kay mrL ssrp2	Drosophila melanogaster (fruit fly)
Nectin/Necl trans heterodimerization	Fasciclin-3	P15278	Fas3	Drosophila melanogaster (fruit fly)
N-HH ligand not bound to PTC receptor complex	Transcriptional activator cubitus interruptus	P19538	ci ci-D	Drosophila melanogaster (fruit fly)
Activation of non-muscle Myosin II	Diego, isoform A Dishevelled associated activator of morphogenesis, isoform B FI18194p1 Frizzled Myosin heavy chain, non-muscle Myosin regulatory light chain sqh Myosin-2 essential light chain Protein prickle Protocadherin-like wing polarity protein stan Ras-like GTP-binding protein Rho1 Rho-associated protein kinase Segment polarity protein dishevelled Serine/threonine-protein phosphatase alpha-2 isoform Serine/threonine-protein phosphatase beta isoform Vang-like protein	A1Z6W3 O45030 P12982 P18537 P40423 P48148 P48462 P51140 P54357 Q7JUF2 Q8IQN4 Q8IRY0 Q99323 Q9U779 Q9V5N8	0573/06 0953/04 CG5600 CG5891 DAAM DAAM1 DGO DMBS DMYPT DMbs Daam Dgo Dmel\CG12342 Dmel\CG14622 Dmel\CG32156 EG:114D9.2 EP(2)2619 EP2619 MBS Mbs Mbs-RI Mlc-c Mypt PP1-9C PP1-BETA-9C Pp1-87B Rhk Rho1 Rok Vang anon-EST:Posey148 dDAAM dDaam daam dgo dsh flw fmi fz l(3)03802 l(3)72Dd l(3)S005331b l(3)S057306 l(3)S057306b l(3)S095304 l(3)j3B4 l(3)j7A1 mbs pk rok sqh stan stbm zip	Drosophila melanogaster (fruit fly)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cdc25-like protein phosphatase twine GH11341p GH17761p LD45860p M-phase inducer phosphatase Ovarian-specific serine/threonine-protein kinase Lok Polyubiquitin Probable 26S proteasome non-ATPase regulatory subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit alpha type-7-1A Proteasome subunit alpha type-7-1B Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Regulatory particle triple-A ATPase 4 Serine/threonine-protein kinase grp Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein proteasome endopeptidase complex	A0AQH0 O18413 O61267 O61661 P0CG69 P12881 P15357 P18053 P20483 P22769 P25161 P26270 P40301 P48601 P55035 Q03019 Q24178 Q27575 Q7K148 Q7KLV9 Q7KMP8 Q7KMQ0 Q8INY4 Q8T915 Q95083 Q9V3G7 Q9V3H2 Q9V3P3 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V436 Q9V5C6 Q9V637 Q9VFS8 Q9VJJ0 Q9VNA5 Q9VUJ1 Q9VW54 Q9VYG1 Q9W1S5 Q9W414 Q9W418 Q9W470 Q9XYN7 Q9XZJ4 R9PY16	0718/06 1(2)05070 1341 16916 17331 31742 3329 718/06 8392 B[[1]] B[[2]] BcDNA.GH12068 BcDNA:GH12068 BcDNA:LD21723 Beta 2 subunit Beta-1 Beta-2 Beta-4 Beta-5 CG12096 CG18282 CG9588 CR11700 CR32744 CT28749 DTS-7 DTS57 DTS7 DUG DmREGgamma DmTBP-1 DmUb DmUbi-p5E Dm_Rpt1 Dm_Rpt3a Dm_Rpt4a Dm_Rpt4b Dm_Rpt5a Dm_Rpt5b Dmel\CG10230 Dmel\CG10370 Dmel\CG1100 Dmel\CG11700 Dmel\CG12161 Dmel\CG12323 Dmel\CG1341 Dmel\CG1591 Dmel\CG16916 Dmel\CG17331 Dmel\CG18341 Dmel\CG31742 Dmel\CG32744 Dmel\CG3329 Dmel\CG3455 Dmel\CG4157 Dmel\CG7762 Dmel\CG8392 Dmel\CG9868 Dmp42D Dmp48A Dmp48B Dox-A2 Dts7 ESTS:143G11T ESTS:199A6T GC17331 LD08717 Mov34 P26s4 PI31 PROS-25 PROS-28.1 PROS-29 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMB5 PSMD13 Pros b5 Pros beta4 Pros-beta-2 Pros-beta-5 Pros-beta-5R1 Pros25 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros28.1A Pros28.1B Pros29 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha3 Prosalpha4 Prosalpha4T1 Prosalpha4T2 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta2R1 Prosbeta2R2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta5R Prosbeta5R1 Prosbeta5R1-RA Prosbeta5R2 Prosbeta7 Psmb2 Q7KMQ0_DROME REG REGgamma RPN1 RPN5 RPT5 RpS27A Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S10b S11 S14 S2 S6 S6' S6B S7 TBP-1 TBP7 Tbp-1 Tbp1 UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Ug anon-AE003657.1 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.116 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 anon-sts41 b2 beta 2 beta-1 beta-2 beta-4 beta-5 beta1 beta2 beta2R1 beta2R2 beta2_dm beta4 beta5 beta5R1 beta5R2 cdc25 dREG dREGgamma dReg dReggamma dRpn12 dRpt1 dRpt5 dbeta5 grp l(1)G0052 l(1)G0114 l(1)G0227 l(1)G0345 l(2)05070 l(2)05070-RA l(2)05643 l(2)43Ed l(3)04210 l(3)DTS7 l(3)S071806 l(3)S071806b lok p30 p39A p42D p48A p48B p50 p55 p97 poly-ub prosbeta prosbeta1 prosbeta2 rpn1 rpn12 rpn5 rpn9 rpt3 stg tbp-1 twe yip5	Drosophila melanogaster (fruit fly)
Interleukin-3, Interleukin-5 and GM-CSF signaling	Protein vav Tyrosine-protein kinase Btk	P08630 Q9NHV9	Btk Btk29A Src2 Src29A Tec29 Vav	Drosophila melanogaster (fruit fly)
Na+/Cl- dependent neurotransmitter transporters	Beta-alanine transporter Carcinine transporter FI01439p FI05810p FI17140p1 FI18149p1 FI18650p1 FI24011p1 GH01326p GH09241p GH10249p GH28654p IP11961p IP21853p IP21962p LP02775p LP04053p MIP13952p Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Organic cation transporter protein Organic cation transporter-like protein Portabella RE69557p RH23644p Sodium-dependent dopamine transporter Sodium-dependent nutrient amino acid transporter 1 Solute carrier family 22 member 3 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Uncharacterized protein, isoform B Uncharacterized protein, isoform B Uncharacterized protein, isoform B Uncharacterized protein	A0A0B4K7V4 A0A0B4KFK6 A1Z8V9 A1ZBC7 B7Z122 D2NUL5 Q7K330 Q7K3M6 Q7K4Y6 Q7KTJ8 Q8IH57 Q95R48 Q95TF4 Q961J5 Q961R9 Q9I7N9 Q9V4E7 Q9VCA0 Q9VCA2 Q9VCJ5 Q9VD40 Q9VDR9 Q9VDS0 Q9VDS2 Q9VDV5 Q9VDV6 Q9VDV7 Q9VDV8 Q9VDV9 Q9VDW0 Q9VFG0 Q9VFG1 Q9VFG2 Q9VIK2 Q9VJR4 Q9VLY3 Q9VLY4 Q9VLY5 Q9VNW8 Q9VNX2 Q9VRQ8 Q9VRR0 Q9VRT4 Q9VSV2 Q9W1J0 Q9W4C5	BG:DS03431.1 Balat CG12588 CG13795-RB CG13796 CG13796-PA CG13796-RA CG14654 CG14856-RA CG1732a CG18590 CG31530 CG31530-RA CG31904-PD CG42510 CG43006 CG4462-RA CG4476-RB CG5226 CG6139 CG6231-RD CG6596 CG6600 CG7342-RA CG7458-RA CG8654-RA CG8850-RB CG9767 CT19169 CT33284 CT42497 CarT DAT DS03431.1 DVMAT DVMAT-A DVMAT-B DmGAT DmNAT2 DmNAT3 DmNAT4 DmNAT5 DmNAT6 DmSLC22A Dmel\CG10251 Dmel\CG10486 Dmel\CG10804 Dmel\CG13793 Dmel\CG13794 Dmel\CG13795 Dmel\CG13796 Dmel\CG14855 Dmel\CG14856 Dmel\CG14857 Dmel\CG15088 Dmel\CG15279 Dmel\CG16727 Dmel\CG1698 Dmel\CG1732 Dmel\CG17751 Dmel\CG17752 Dmel\CG31904 Dmel\CG33296 Dmel\CG33528 Dmel\CG42269 Dmel\CG43066 Dmel\CG44098 Dmel\CG4459 Dmel\CG4462 Dmel\CG4465 Dmel\CG4476 Dmel\CG4630 Dmel\CG5549 Dmel\CG5592 Dmel\CG6126 Dmel\CG6231 Dmel\CG6356 Dmel\CG7084 Dmel\CG7333 Dmel\CG7342 Dmel\CG7442 Dmel\CG7458 Dmel\CG8654 Dmel\CG8850 GAT Gat GlyT List NAAT1 Orct Orct2 SLC22A Slc22a15 VMAT Vmat Vmt anon-WO0149848.1 anon-WO0149848.11 anon-WO0149848.5 anon-WO0149848.7 anon-WO0149848.9 dGAT dGlyT dVMAT fmn gat l(2)SH0459 l(2)SH2 0459 prt vmat	Drosophila melanogaster (fruit fly)
HuR (ELAVL1) binds and stabilizes mRNA	Acidic leucine-rich nuclear phosphoprotein 32 family member A Exportin-1 Found in neurons, isoform A Nuclear pore complex protein Nup214 Protein SET Protein eiger Protein elav Protein kinase C, brain isozyme Putative protein kinase C delta type homolog RNA-binding protein 9, isoform J	M9PBZ2 P05130 P16914 P53997 P83099 Q8MUJ1 Q9TVM2 Q9V895 Q9VYI0 Q9W1X4	Anp32a BEST:HL02010 BcDNA:HL02010 BcDNA:RE25290 CG15402 CR32646 Crm1 Darth Dmel\CG3151 Dmel\CG4396 FNE Fne MRE28 Mapmodulin Nup214 PKC1 Pkc53E Pkcdelta RBP9 RBP9-2 RRM10 RRM9 Rbp10 Rbp9 Rpb9 Set cg4396 egr elav emb fes fne fne-RB fs(2)B lincRNA.985 rbp rbp9 rbp9a rrm10 rrm9	Drosophila melanogaster (fruit fly)
Surfactant metabolism	ATP binding cassette subfamily A, isoform B Adenosine receptor, isoform A BcDNA.GH08312 Box A-binding factor Cathepsin D FI19405p1 GATA-binding factor A GATAe, isoform A Peptidase A1 domain-containing protein Testin adenosine deaminase	A1ZAT5 P52168 P52172 Q7K485 Q9VAA2 Q9VEK4 Q9VF00 Q9VKZ0 Q9VRG4 Q9VVK5 Q9Y125	ABCA ABF ADGDF-A ADGF ADGF-A Abca3 Adgf-A Adgf-a AdgfA AdoR Apa BcDNA.GH08312 BcDNA:GH08312 CATH CG10278-PA CG17134 CT3996 CTSD CathD DAPA DmAdoR Dmel\CG10278 Dmel\CG12070 Dmel\CG1548 Dmel\CG1718 Dmel\CG5034 Dmel\CG5860 Dmel\CG5992 Dmel\CG6522 Dmel\CG9753 FBgn0038506 GATA-A GATAd GATAd-RA GATAe Ov9 P110 Sap-R Sap-r Sapr T17 Tes adgf-a adgfa adoR anon-EST:ParkEST270 anon-WO0170980.109 anon-WO0170980.110 cathD dABCA dADOR dAdoR dGATA-D dGATA-E dGATAd dGATAe dTES pnr sap-r srp	Drosophila melanogaster (fruit fly)
Extra-nuclear estrogen signaling	Arginine methyltransferase 1 Arginine methyltransferase 2, isoform A Arginine methyltransferase 6 Arginine methyltransferase 8 Arginine methyltransferase 9 Connector of kinase to AP-1, isoform E DShc protein Estrogen-related receptor splice variant FI14603p G protein alpha i subunit Gbeta5 Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma-1 Guanine nucleotide-binding protein subunit gamma-e Guanine nucleotide-binding protein subunit gamma Heat shock protein 83 Insulin-like receptor Knirps-related protein Nitric oxide synthase Palmitoyltransferase Protein embryonic gonad RAC serine/threonine-protein kinase Tyrosine-protein kinase Src64B Uncharacterized protein, isoform D Zygotic gap protein knirps sphingosine kinase	A0A0B4K838 D3DML3 P00528 P02828 P09208 P10734 P13054 P15370 P20353 P26308 P29829 P38040 Q27571 Q7K3T4 Q8INB9 Q8IQ15 Q8SX32 Q8WS79 Q9NFZ3 Q9V3C8 Q9VFP8 Q9VFP9 Q9VGW7 Q9VQX9 Q9VYY8 Q9W3J1 X2JB47	5836 Akt Akt1 Art1 Art2 Art6 Art8 Art9 CBP1 CG10022 CG15844 CG31960-RA CKA Cka Cka-RB D-Shc DART1 DART2 DART6 DART8 DART9 DSHC Dart Dart1 Dart2 Dart8 Dcka Derr Dir-a Dmel\CG10763 Dmel\CG16840 Dmel\CG1747 Dmel\CG31960 Dmel\CG32152 Dmel\CG3675 Dmel\CG3715 Dmel\CG43324 Dmel\CG6554 Dmel\CG7392 Dmel\CG7404 Dmel\CG8314 Dmel\CG9927 Dmel\CG9929 ERR G-OA65C G-beta-5 G-ialpha65A G1 GNB5 G[[beta5]] G[[beta]] Galphai Gb13F Gb76C Gbe Gbeta Gbeta 5 Gbeta13F Gbeta5 Gbeta76C Gbetae Gbetagamma Ggamma1 Ggamma30A Ggammae Hsp82 Hsp83 Hsp90 IR InR Inr-a NR0A1 NR0A2 NR0A3 NR3B4 Nos SK1 Shc Shc-RA Sk1 SphK1 Sphk1 Src1 Src64B anon-WO0118547.93 anon-WO0172774.174 anon-WO0172774.175 anon-WO0172774.177 anon-WO0172774.179 cka dART8 dERR dShc dart1 dshc eg egon kni knrl l(2)05836 l(2)s1883 shc spry	Drosophila melanogaster (fruit fly)
Degradation of PER	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory complex subunit p42D 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Circadian locomoter output cycles protein kaput Discs overgrown protein kinase GH11341p LD25378p Period circadian protein Polyubiquitin Probable 26S proteasome complex subunit sem1 Probable 26S proteasome non-ATPase regulatory subunit 3 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit beta type-1 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein cycle Slimb Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O18413 O44382 O61734 O61735 O76324 P07663 P0CG69 P12881 P15357 P18101 P22769 P25161 P26270 P40301 P40304 P48601 P55035 Q7KLV9 Q7KMP8 Q7KMQ0 Q8SYQ2 Q95083 Q9NHX7 Q9U7A2 Q9V3G7 Q9V3H2 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V436 Q9V5C6 Q9VJJ0 Q9VKZ8 Q9VM46 Q9VNA5 Q9VUJ1 Q9VW54 Q9XYN7 Q9XZ61 Q9XZJ4 Q9Y1A7	0718/06 1341 16916 17331 3329 718/06 B[[2]] BcDNA.GH12068 BcDNA.LD24440 BcDNA:GH12068 BcDNA:LD21723 BcDNA:LD24440 Beta 2 subunit Beta-2 Beta-4 CLOCK CT28749 Clk DTS-7 DTS57 DTS7 DUG DmTBP-1 DmUsp14 Dm_Rpt1 Dm_Rpt3a Dm_Rpt5a Dm_Rpt5b Dmel\CG10230 Dmel\CG10370 Dmel\CG1100 Dmel\CG1341 Dmel\CG16916 Dmel\CG17331 Dmel\CG3297 Dmel\CG3329 Dmel\CG3431 Dmel\CG4157 Dmel\CG5384 Dmel\CG7762 Dmp48A Dmp48B Dox-A2 Dts7 GC17331 Mnd Mov34 P26s4 PAS1 PROS-25 PROS-26 PROS-28.1 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMD13 Pros beta4 Pros-beta-2 Pros-beta-5 Pros25 Pros26 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha4 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta6 Prosbeta7 Psmb2 Q7KMQ0_DROME Q9VKZ8 Q9XZ61 RPN1 RPN5 RPT5 RpL40 RpS27A Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S11 S14 S2 S6 S6' S6B S7 SG29 Sem1 TBP-1 TBP7 Tbp-1 Tbp1 UB3-D UBI-F52 UBI-F80 UCH UCH 37 UCHL5 USP14 Ubi-f Ubi-m Ubi-p63E Ubp6p Uch-L3 Uch-L5 Uch37 Uchl3 Ug Usp14 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 b2 beta 2 beta-2 beta-4 beta2 beta2_dm beta4 beta5 cyc dRpn12 dRpt1 dRpt5 dUCH37 dUCHL5 dbt dco jrk l(1)G0052 l(2)05070 l(2)05643 l(2)43Ed l(3)04210 l(3)73Ai l(3)B5 l(3)DTS7 l(3)S071806 l(3)S071806b l(3)SG29 l(3)ds-5 l(3)ds5 l(3)o52 md mnd p30 p37A p39A p48A p48B p50 p55 p97 per prosbeta prosbeta2 rpn1 rpn12 rpn5 rpn9 rpt3 slimb slmb tbp-1 uch-L3 uch-l5 uchl3 usp14 yip5	Drosophila melanogaster (fruit fly)
Class C/3 (Metabotropic glutamate/pheromone receptors)	IP03705p Metabotropic GABA-B receptor subtype 2, isoform C Metabotropic glutamate receptor	A0A0B4LHR4 P91685 Q9V3Q9	BG:DS00929.6 BcDNA:GH07312 D-GABA-B-R1 D-GABA[[B]]R1 D-GABA[[B]]R2 D-Gaba1 D-Gaba2 Dmel\CG15274 Dmel\CG6706 GABA GABA B R2 GABA(B)R1 GABA-B-R1 GABA-B-R2 GABA-BR1 GABA-BR2 GABA-[[B]]-R1 GABA-[[B]]R2 GABA1 GABAB(R1) GABAB-R1 GABABR-R2 GABABR2 GABA[[B]] GABA[[B]]-R GABA[[B]]-R1 GABA[[B]]-R2 GABA[[B]]R GABA[[B]]R1 GABA[[B]]R2 GB1 GB2 GBR GH07312 Gaba-b-r1 Glu-RA GluRA anon-WO0170980.175 anon-WO0170980.176 anon-WO0170980.58 anon-WO0170980.59 dGB1 mGluR mGluRA	Drosophila melanogaster (fruit fly)
Crosslinking of collagen fibrils	Dorsal-ventral patterning protein tolloid Lysyl oxidase-like 2 Protein tolkin	P25723 Q9VC47 Q9W2C9	Dmel\CG4402 Dmloxl-2 LOX Loxl2 dmlox-2 lox2 tld tlr tlr-1 tok	Drosophila melanogaster (fruit fly)
Orc1 removal from chromatin	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division control protein Cullin homolog 1 Cyclin-dependent kinase 2 DNA replication licensing factor MCM4 DNA replication licensing factor Mcm2 DNA replication licensing factor Mcm3 DNA replication licensing factor Mcm5 DNA replication licensing factor Mcm6 DNA replication licensing factor Mcm7 DNA replication licensing factor REC Double parked, isoform A G2/mitotic-specific cyclin-A GEO01111p1 GH11341p GH17761p LD45860p Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin Probable 26S proteasome non-ATPase regulatory subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit alpha type-7-1A Proteasome subunit alpha type-7-1B Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RING-box protein 1A Regulatory particle triple-A ATPase 4 S-phase kinase-associated protein 2, isoform A Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein proteasome endopeptidase complex	A0AQH0 O16810 O18413 O77430 P0CG69 P12881 P14785 P15357 P18053 P22769 P23573 P25161 P26270 P40301 P48601 P49735 P55035 Q24168 Q24169 Q24178 Q24311 Q26454 Q27575 Q7JVY2 Q7K148 Q7K2L1 Q7KLV9 Q7KMP8 Q7KMQ0 Q7YZ95 Q8INY4 Q8T915 Q95083 Q9V3G7 Q9V3H2 Q9V3P3 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V436 Q9V461 Q9V5C6 Q9V637 Q9VF30 Q9VFS8 Q9VGW6 Q9VJJ0 Q9VNA5 Q9VSM9 Q9VUJ1 Q9VW54 Q9VYG1 Q9W102 Q9W1S5 Q9W414 Q9W418 Q9W470 Q9W5E1 Q9XYN7 Q9XYU0 Q9XYU1 Q9XZJ4 Q9Y1B2 R9PY16	0718/06 1(2)05070 1341 153298_at 16916 17331 19k 31742 3329 718/06 8392 B[[1]] B[[2]] BcDNA.GH12068 BcDNA:GH12068 BcDNA:LD21723 Beta 2 subunit Beta-1 Beta-2 Beta-4 Beta-5 CDC6 CDT1 CDT1/DUP CG12096 CG18282 CG34315-RB CG9588 CR11700 CR32744 CT28749 Cdc6 Cdk2 Cdt1 Cul1 CycA DTS-7 DTS57 DTS7 DUG DUP DUP/CDT1 DmCdc6 DmORC3 DmORC4 DmOrc3 DmREGgamma DmTBP-1 DmUb DmUbi-p5E Dm_Rpt1 Dm_Rpt3a Dm_Rpt4a Dm_Rpt4b Dm_Rpt5a Dm_Rpt5b Dmel\CG10230 Dmel\CG10370 Dmel\CG1100 Dmel\CG11700 Dmel\CG12161 Dmel\CG12323 Dmel\CG1341 Dmel\CG1591 Dmel\CG16916 Dmel\CG16983 Dmel\CG17331 Dmel\CG18341 Dmel\CG2917 Dmel\CG31742 Dmel\CG32744 Dmel\CG3329 Dmel\CG3455 Dmel\CG4088 Dmel\CG4157 Dmel\CG5971 Dmel\CG7762 Dmel\CG8171 Dmel\CG8392 Dmel\CG9772 Dmel\CG9868 Dmp42D Dmp48A Dmp48B Dox-A2 Dredd Dts7 Dup EG:115C2.4 ESTS:143G11T ESTS:199A6T F-box FBXL1 GC17331 LAT LD08717 Lat Mcm2 Mcm3 Mcm3-RA Mcm5 Mcm6 Mcm7 Mov34 ORC ORC3 ORC4 Orc1 Orc2 Orc3 Orc4 Orc5 Orc6 P26s4 PI31 PROS-25 PROS-28.1 PROS-29 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMB5 PSMD13 Pros b5 Pros beta4 Pros-beta-2 Pros-beta-5 Pros-beta-5R1 Pros25 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros28.1A Pros28.1B Pros29 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha3 Prosalpha4 Prosalpha4T1 Prosalpha4T2 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta2R1 Prosbeta2R2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta5R Prosbeta5R1 Prosbeta5R1-RA Prosbeta5R2 Prosbeta7 Psmb2 Q7KMQ0_DROME REG REGgamma RPN1 RPN5 RPT5 Roc1a RpS27A Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S10b S11 S14 S2 S6 S6' S6B S7 SKP1 SKP2 SKPA Skp Skp1 Skp2 SkpA TBP-1 TBP7 Tbp-1 Tbp1 UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Ug anon-AE003657.1 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.116 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 anon-WO0257455.31 anon-WO03040301.234 anon-WO03040301.236 anon-WO03040301.238 anon-sts41 b2 beta 2 beta-1 beta-2 beta-4 beta-5 beta1 beta2 beta2R1 beta2R2 beta2_dm beta4 beta5 beta5R1 beta5R2 cdc2c cdc6 cdt1 cdt1/dup cul-1 dREG dREGgamma dReg dReggamma dRpn12 dRpt1 dRpt5 dSKP1 dSkip-1 dSkp-1 dSkp2 dSkpA dbeta5 dmOrc4 dpa dskpA dup fs(2)51Fa fs(2)PA77 fs(2)ltoPA77 l(1)G0037 l(1)G0052 l(1)G0058 l(1)G0109 l(1)G0114 l(1)G0227 l(1)G0345 l(1)G0389 l(2)05070 l(2)05070-RA l(2)05643 l(2)43Ed l(2)49Fd l(2)51Ec l(2)k03308 l(2)vr6 l(3)04210 l(3)DTS7 l(3)S071806 l(3)S071806b lat lat-RA latheo lin19 orc3 orc4 p30 p39A p42D p48A p48B p50 p55 p97 poly-ub prosbeta prosbeta1 prosbeta2 rDmORC rec rpn1 rpn12 rpn5 rpn9 rpt3 skpA skpA-RC skpA-RH spkA tbp-1 vr-6 vr6 yip5	Drosophila melanogaster (fruit fly)
Insulin processing	Ero1-like protein Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 4 Exocyst complex component 5 Exocyst complex component 6 Exocyst complex component 7 Exocyst complex component 8 LD05335p Protein disulfide-isomerase	P54399 Q7KRZ3 Q8T0G1 Q9V3A6 Q9V8K2 Q9VDE6 Q9VNH6 Q9VQQ9 Q9VSJ8 Q9VVG4 Q9XTM1	BEST:CK02137 CK02137 DExo84 Dmel\CG11163 Dmel\CG6095 Ero1L Exo70 Exo84 Exo84p Pdi Sec10 Sec15 Sec3 Sec5 Sec6 Sec8 ZNT41F ZnT41F anon-WO0153538.55 cg11163 dZNT41F dZnT41F exo84 onr	Drosophila melanogaster (fruit fly)
Downregulation of ERBB2 signaling	Cullin-5 E3 ubiquitin-protein ligase CHIP Epidermal growth factor receptor GH17761p Heat shock protein 83 Hsp90 co-chaperone Cdc37 Low-density lipoprotein receptor-related protein Polyubiquitin Protein cueball Protein vein Tyrosine-protein kinase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A1Z9D7 P02828 P04412 P0CG69 P15357 Q24276 Q8INJ8 Q94918 Q95RU0 Q9VAQ0 Q9W418 Q9XYW6 R9PY16	Arr BEST:CK00539 CG17309 CG18282 CG32852 CHIP CK00539 CR11700 CR32744 CSK CT15575 CUL5 Cdc37 Chip Csk Cul-5 Cul-5-RA Cul5 Cullin5 DCsk DER Dm Arr DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG1401 Dmel\CG32744 Dmel\CG42317 Dmel\CG5203 Dmel\CG5912 E(sev)3B ESTS:143G11T ESTS:199A6T Egfr Hsp82 Hsp83 Hsp90 Irp6 LRP LRP/Arr LRP5/6 LRP6 RpS27A STUB1 Src Stub1 UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin anon-sts41 arr arr-RA c-erbB csk cue cul-5 cul5 d-Csk dCHIP dCSK dCsk dcsk ddd flik l(2)k08131 l(3)S017909 l(3)j1D8 poly-ub top vn	Drosophila melanogaster (fruit fly)
Catecholamine biosynthesis	Aromatic-L-amino-acid decarboxylase Tyramine beta-hydroxylase Tyrosine 3-monooxygenase	P05031 P18459 Q86B61	Ddc TH Tbh ple	Drosophila melanogaster (fruit fly)
Sema4D induced cell migration and growth-cone collapse	Epidermal growth factor receptor MIP07328p Plexin-B Ras-like GTP-binding protein Rho1 Rho guanine nucleotide exchange factor 2, isoform D Rho-associated protein kinase Semaphorin 2b, isoform D Semaphorin-1A Semaphorin-2A	A0A0B4KG38 A1ZAN6 P04412 P48148 Q24322 Q24323 Q7KK54 Q9V4A7 Q9VXE3	BcDNA:GH03186 CG30322 CG4383 D-semaIII DER DROK DRhk DRhoGEF DRhoGEF2 DRok Dmel\CG33960 Dmel\CG6446 Dmel\CG9635 Dmel\CG9774 DrhoGEF2 Drok Dsema-I Egfr Gef2 MRLC PlexB RG2 ROCK ROCK-1 ROCK1 ROCK2 ROK ROKalpha/beta Rhk Rho-GEF2 Rho1 RhoGEF RhoGEF2 RhoGF2 RhoGef2 RhoK Rock Rok Rok/ROCK Sema 1b Sema III Sema-1a Sema-1b Sema-1b-RB Sema-2a Sema-2b Sema1a Sema1b Sema2a Sema2b SemaIIB Su(Rho1)2B T2 c-erbB dROK dRhoGEF dRhoGEF2 dRok drok l(2)04291 rhoGEF2 rhogef2 rok rok-RA sema-2b sema-III sema1b sema2b semaphorin-like shar top	Drosophila melanogaster (fruit fly)
MAPK6/MAPK4 signaling	Cdc42 homolog ETV5-related protein Ets96B Forkhead box protein O Ras-related protein Rac1 Serine/threonine-protein kinase Pak Taiman, isoform G non-specific serine/threonine protein kinase	A0A0B4KGS4 M9ND53 P40792 P40793 Q8MRW5 Q95V55 Q9VI13	58/2 Afx CG18494 Cdc42 D-Pak3 DAIB1 DPAK DPAK3 DPak3 DmPAK3 DmTai DmTaiman Dmel\CG13109 Dmel\CG14895 Dpak1 Dpak3 EP(2)2630 Ets96B NEST:bs13g05 PAK-3 PAK3 PaK3 Pak Pak3 Rac1 RacA TAI Tai Taiman anon-WO0118547.285 bs13g05.y1 dPAK3 dpak3 foxo l(2)01351 l(2)k05802 l(2)k05809 pak3 tai	Drosophila melanogaster (fruit fly)
PI-3K cascade:FGFR3	FI23523p1 Fibroblast growth factor receptor homolog 1 Fibroblast growth factor receptor homolog 2 Fibroblast growth factor Growth factor receptor-bound protein 2 Pi3K21B, isoform B Protein daughter of sevenless	Q07407 Q08012 Q09147 Q7KTZ2 Q9VDT9 Q9VLL4 Q9VZZ9	BNL Bnl Branchless CG13398-RA DFGF DmBnl Dmel\CG13398 Dmel\CG2699 Dmel\CG4608 Dp60 E(sev)2B FGF FR1 FR2 Grb2 HD-311 P60 PI(3)K PI3 kinase PI3K PI3K-p60 PI3K-reg PI3K21B PI[[3]]K Pi3K Pi3K21B Pi3Kp60 Pi3k21B Tk1 Tk2 bnl btl dFGF dP60 dPI3K deltap60 dos dp60 drk droPIK57 htl l(3)06916 l(3)neo52 p60 p85	Drosophila melanogaster (fruit fly)
G alpha (z) signalling events	Alpha2-adrenergic-like octopamine receptor, isoform B Gbeta5 Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma-1 Guanine nucleotide-binding protein subunit gamma-e Guanine nucleotide-binding protein subunit gamma Tyramine/octopamine receptor	A0A0B4K838 A0A0B4KHD0 P22270 P26308 P29829 P38040 Q9NFZ3 Q9W3J1	CG15844 DmOctalpha2R Dmel\CG10763 Dmel\CG18208 Dmel\CG43324 G-beta-5 G1 GNB5 G[[beta5]] G[[beta]] Gb13F Gb76C Gbe Gbeta Gbeta 5 Gbeta13F Gbeta5 Gbeta76C Gbetae Gbetagamma Ggamma1 Ggamma30A Ggammae OcR Oct-TyrR Octalpha2R OctyR99AB TYR TyrR	Drosophila melanogaster (fruit fly)
Assembly of active LPL and LIPC lipase complexes	FI01450p FI01825p FI22312p1 Furin-like protease 1, isoforms 1/1-X/2 GH01208p GH15759p IP10831p IP12247p IP13478p LD47264p LP07116p LP08709p Lipase domain-containing protein Lipase domain-containing protein Lipase domain-containing protein Lipase domain-containing protein MIP10846p1 MIP30168p Protein quiver RE23868p RE51539p RE56633p RH13166p RT07891p Uncharacterized protein, isoform A Uncharacterized protein, isoform A Uncharacterized protein, isoform B Uncharacterized protein, isoform B Uncharacterized protein, isoform C Uncharacterized protein, isoform C Uncharacterized protein, isoform C	A1ZAL5 A1ZBJ7 A8DYT7 M9MRT1 M9NFL7 P26016 Q0E8T1 Q4V566 Q7K3Z8 Q9V9P0 Q9VB88 Q9VB89 Q9VB90 Q9VB91 Q9VB92 Q9VB93 Q9VB94 Q9VBQ2 Q9VEY9 Q9VJH1 Q9VLU1 Q9VQ96 Q9VQC2 Q9VRW5 Q9VU78 Q9VX01 Q9VX69 Q9VX70 Q9VZN6 Q9W304 Q9W448	141233_at BP1009 CG10163-RA CG11535 CG18641-RB CG31684 CG31686 CG34448-RA CG6847-RA CG9966 CT41369 DmelL1 DmelL2 DmelL3 DmelL4 DmelL5 DmelL6 DmelL7 Dmel\CG10116 Dmel\CG10163 Dmel\CG10357 Dmel\CG13282 Dmel\CG14034 Dmel\CG17191 Dmel\CG17192 Dmel\CG17292 Dmel\CG18258 Dmel\CG18641 Dmel\CG1986 Dmel\CG34045 Dmel\CG34447 Dmel\CG34448 Dmel\CG4267 Dmel\CG4582 Dmel\CG4979 Dmel\CG5162 Dmel\CG5665 Dmel\CG5966 Dmel\CG6271 Dmel\CG6277 Dmel\CG6283 Dmel\CG6295 Dmel\CG6296 Dmel\CG6431 Dmel\CG6472 Dmel\CG6675 Dmel\CG6847 Dmel\CG7367 Fur1 TL anon-SAGE:Wang-051 anon-SAGE:Wang-122 cg5665 chr2L_10724193_10724543.0 sxe2	Drosophila melanogaster (fruit fly)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Aldehyde reductase Y, isoform D Aldo-keto reductase 1B, isoform C BcDNA.GH10614 FI02878p FI19917p1 Glutathione S-transferase S1 LD24696p NADP-dependent oxidoreductase domain-containing protein Prostaglandin E synthase 3 homolog Uncharacterized protein, isoform A Uncharacterized protein glutathione transferase glutathione transferase glutathione transferase	D2A6K3 M9PF61 P41043 Q7JVH6 Q86B54 Q8IND7 Q8SY19 Q9V420 Q9VH95 Q9VTL0 Q9VTY2 Q9VZK8 Q9Y112 X2JF29	34F4T AKR ARY Akr1B Aldehyde reductase BcDNA.GH10614 BcDNA:GH10614 BcDNA:RE10696 BcDNA:RH14671 BcDNA:RH59553 CG14872 CG32101 CG33178-RA CG5579 CG6083-RA Dmel\CG10638 Dmel\CG10863 Dmel\CG12766 Dmel\CG1742 Dmel\CG33177 Dmel\CG33178 Dmel\CG40064 Dmel\CG4086 Dmel\CG44014 Dmel\CG6083 Dmel\CG6084 Dmel\CG9436 ESTS:34F4T GST2 GSTS1-1 GstS1 Mgst1 Mgstl Su(P) Y anon-WO0172774.89 dAR1 dm1/AKR2E3 p23	Drosophila melanogaster (fruit fly)
Adrenaline,noradrenaline inhibits insulin secretion	Alpha2-adrenergic-like octopamine receptor, isoform B G protein alpha i subunit Gbeta5 Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma-1 Guanine nucleotide-binding protein subunit gamma-e Guanine nucleotide-binding protein subunit gamma Tyramine/octopamine receptor adenylate cyclase	A0A0B4K838 A0A0B4KHD0 A8JNU1 P20353 P22270 P26308 P29829 P38040 Q9NFZ3 Q9W3J1	AC Ago2 CG12436 CG15844 CG32158 CG42513 DmOctalpha2R Dmel\CG10763 Dmel\CG18208 Dmel\CG43324 Dmel\CG43373 G-OA65C G-beta-5 G-ialpha65A G1 GNB5 G[[beta5]] G[[beta]] Galphai Gb13F Gb76C Gbe Gbeta Gbeta 5 Gbeta13F Gbeta5 Gbeta76C Gbetae Gbetagamma Ggamma1 Ggamma30A Ggammae OcR Oct-TyrR Octalpha2R OctyR99AB TYR TyrR	Drosophila melanogaster (fruit fly)
Glutathione conjugation	Aldehyde reductase Y, isoform D Aldo-keto reductase 1B, isoform C BcDNA.GH10614 FI19917p1 GH16740p Glutathione S transferase O1 Glutathione S transferase O2, isoform A Glutathione S transferase O3 Glutathione S transferase T1 Glutathione S transferase T2 Glutathione S transferase T3, isoform B Glutathione S-transferase S1 LD24696p NADP-dependent oxidoreductase domain-containing protein Probable maleylacetoacetate isomerase 2 Pyrimidodiazepine synthase S-formylglutathione hydrolase Uncharacterized protein, isoform A glutathione transferase	A1Z7X7 D2A6K3 E1JJS1 M9PF61 P41043 Q7JVH6 Q7K0B6 Q7KSB5 Q8MRM0 Q8SY19 Q9VHD2 Q9VSL2 Q9VSL3 Q9VSL5 Q9VSL6 Q9VTL0 Q9VTY2 Q9VZK8 Q9Y112	34F4T AKR ARY Akr1B Aldehyde reductase BcDNA.GH10614 BcDNA:GH10614 BcDNA:RE10696 BcDNA:RE63575 BcDNA:RH59553 CG12930 CG12930A CG12930B CG32101 CG6083-RA CG6673-A CG6673-B CG6673A CG6673B DmGSTO1 DmGSTO2a DmGSTO2b DmGSTO3 DmGSTT1 DmGSTT2 DmGSTT3a DmGSTT3b DmGSTT4 Dmel\CG10638 Dmel\CG10863 Dmel\CG12766 Dmel\CG1681 Dmel\CG1702 Dmel\CG1742 Dmel\CG30000 Dmel\CG30005 Dmel\CG40064 Dmel\CG4390 Dmel\CG6083 Dmel\CG6084 Dmel\CG6662 Dmel\CG6673 Dmel\CG6776 Dmel\CG9436 ESTS:34F4T GST-theta GST2 GSTO1 GSTO2 GSTO2a GSTO2b GSTO3 GSTS1-1 GSTT1 GSTT2 GSTT3 GSTT3a GSTT3b GSTT4 GstO1 GstO2 GstO3 GstS1 GstT1 GstT2 GstT3 GstT4 GstZ2 Mgst1 Mgstl T14 Y anon-EST:Posey29 anon-WO0172774.89 cg1702 dAR1 dGstO1 dm1/AKR2E3 gsto2 gstt1 gstt2 gstt3 gstt4 se	Drosophila melanogaster (fruit fly)

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