GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **2074** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Loss of MECP2 binding ability to 5mC-DNA	Histone deacetylase 1 Paired amphipathic helix protein Sin3a	Q13547 Q96ST3	HDAC1 RPD3L1 SIN3A	Homo sapiens (human)
Zinc influx into cells by the SLC39 gene family	Metal cation symporter ZIP14 Metal cation symporter ZIP8 Zinc transporter SLC39A7 Zinc transporter ZIP10 Zinc transporter ZIP1 Zinc transporter ZIP2 Zinc transporter ZIP3 Zinc transporter ZIP4 Zinc transporter ZIP5 Zinc transporter ZIP6	Q13433 Q15043 Q6P5W5 Q6ZMH5 Q92504 Q9BRY0 Q9C0K1 Q9NP94 Q9NY26 Q9ULF5	BIGM103 HKE4 IRT1 KIAA0062 KIAA1265 LIV1 RING5 SLC39A1 SLC39A10 SLC39A14 SLC39A2 SLC39A3 SLC39A4 SLC39A5 SLC39A6 SLC39A7 SLC39A8 ZIP1 ZIP10 ZIP14 ZIP2 ZIP3 ZIP4 ZIP5 ZIP6 ZIP8 ZIRTL	Homo sapiens (human)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 1 Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein 5 High affinity choline transporter 1 Multidrug and toxin extrusion protein 1 Multidrug and toxin extrusion protein 2 Sodium-dependent organic anion transporter Urea transporter 1 Urea transporter 2	Q13336 Q15849 Q3KNW5 Q53GD3 Q86VL8 Q8IWA5 Q8N4M1 Q8NCS7 Q8WWI5 Q96FL8 Q9GZV3	C6orf29 CD92 CDW92 CHT1 CTL1 CTL2 CTL3 CTL4 CTL5 HUT11 HUT2 JK MATE1 MATE2 NG22 RACH1 SLC10A6 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 SLC47A1 SLC47A2 SLC5A7 SOAT TPPT1 UT1 UT2 UTE	Homo sapiens (human)
Leukotriene receptors	Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Uracil nucleotide/cysteinyl leukotriene receptor	Q13304 Q15722 Q9NPC1 Q9NS75 Q9Y271	BLT BLT1 BLT2R BLTR BLTR2 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 GPR16 GPR17 LTB4R LTB4R2 P2RY7	Homo sapiens (human)
Sodium-coupled sulphate, di- and tri-carboxylate transporters	Na(+)/citrate cotransporter Na(+)/dicarboxylate cotransporter 3 Solute carrier family 13 member 1 Solute carrier family 13 member 2 Solute carrier family 13 member 4	Q13183 Q86YT5 Q8WWT9 Q9BZW2 Q9UKG4	NACT NADC1 NADC3 NAS1 NASI1 SDCT1 SDCT2 SLC13A1 SLC13A2 SLC13A3 SLC13A4 SLC13A5 SUT1	Homo sapiens (human)
Signalling to ERK5	Dual specificity mitogen-activated protein kinase kinase 5 Mitogen-activated protein kinase 7	Q13163 Q13164	BMK1 ERK5 MAP2K5 MAPK7 MEK5 MKK5 PRKM7 PRKMK5	Homo sapiens (human)
Coenzyme A biosynthesis	Bifunctional coenzyme A synthase Dephospho-CoA kinase domain-containing protein Pantothenate kinase 1 Pantothenate kinase 2, mitochondrial Pantothenate kinase 3 Phosphopantothenate--cysteine ligase Phosphopantothenoylcysteine decarboxylase	Q13057 Q8TE04 Q8WVC6 Q96CD2 Q9BZ23 Q9H999 Q9HAB8	C20orf48 COAB COAC COASY DCAKD PANK PANK1 PANK2 PANK3 PPCDC PPCS	Homo sapiens (human)
Defective RIPK1-mediated regulated necrosis	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein	Q12933 Q13158 Q13546 Q14790 Q15628	CASP8 FADD MCH5 MORT1 RIP RIP1 RIPK1 TRADD TRAF2 TRAP3	Homo sapiens (human)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	Cell division cycle protein 20 homolog Mitotic spindle assembly checkpoint protein MAD2A	Q12834 Q13257	CDC20 MAD2 MAD2L1	Homo sapiens (human)
MPS IX - Natowicz syndrome	Hyaluronidase-1	Q12794	HYAL1 LUCA1	Homo sapiens (human)	G35674CY
Acetylcholine inhibits contraction of outer hair cells	Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Neuronal acetylcholine receptor subunit alpha-10 Neuronal acetylcholine receptor subunit alpha-9 Small conductance calcium-activated potassium channel protein 2	Q12791 Q16558 Q9GZZ6 Q9H2S1 Q9UGM1	CHRNA10 CHRNA9 KCNMA KCNMA1 KCNMB1 KCNN2 NACHRA10 NACHRA9 SLO	Homo sapiens (human)
Defective MGAT2 causes CDG-2a	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2	Homo sapiens (human)
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
Reactions specific to the hybrid N-glycan synthesis pathway	Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Q09327	GGNT3 MGAT3	Homo sapiens (human)
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)	Sodium-dependent phosphate transporter 2	Q08357	GLVR2 PIT2 SLC20A2	Homo sapiens (human)
Sodium-coupled phosphate cotransporters	Sodium-dependent phosphate transporter 1 Sodium-dependent phosphate transporter 2	Q08357 Q8WUM9	GLVR1 GLVR2 PIT1 PIT2 SLC20A1 SLC20A2	Homo sapiens (human)
NTRK3 as a dependence receptor	Apoptosis regulator BAX NT-3 growth factor receptor Negative elongation factor B	Q07812 Q16288 Q8WX92	BAX BCL2L4 COBRA1 KIAA1182 NELFB NTRK3 TRKC	Homo sapiens (human)
Apoptotic factor-mediated response	Complement component 1 Q subcomponent-binding protein, mitochondrial Tumor suppressor ARF	Q07021 Q8N726	C1QBP CDKN2 CDKN2A GC1QBP HABP1 MLM SF2P32	Homo sapiens (human)
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function	Complement component 1 Q subcomponent-binding protein, mitochondrial Tumor suppressor ARF	Q07021 Q8N726	C1QBP CDKN2 CDKN2A GC1QBP HABP1 MLM SF2P32	Homo sapiens (human)
Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1)	Sodium-dependent phosphate transport protein 2A	Q06495	NPT2 SLC17A2 SLC34A1	Homo sapiens (human)
mRNA decay by 3' to 5' exoribonuclease	7-methylguanosine phosphate-specific 5'-nucleotidase Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 HBS1-like protein Superkiller complex protein 2 Superkiller complex protein 3 Superkiller complex protein 8 m7GpppX diphosphatase	Q06265 Q13868 Q15024 Q15477 Q5RKV6 Q6PGP7 Q969T7 Q96B26 Q96C86 Q9GZS3 Q9NPD3 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2 Q9Y450	CML28 CSL4 DCPS DCS1 DDX13 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 HBS1 HBS1L HINT5 KIAA0116 KIAA0372 KIAA1008 KIAA1038 MTR3 NT5C3B NT5C3L OIP2 PMSCL1 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SKI2W SKI6 SKIC2 SKIC3 SKIC8 SKIV2 SKIV2L TTC37 W WDR61	Homo sapiens (human)
Defective GFPT1 causes CMSTA1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	Q06210	GFAT GFPT GFPT1	Homo sapiens (human)
MECP2 regulates transcription of genes involved in GABA signaling	Glutamate decarboxylase 1 Glutamate decarboxylase 2	Q05329 Q99259	GAD GAD1 GAD2 GAD65 GAD67	Homo sapiens (human)
Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)	Ammonium transporter Rh type A	Q02094	RH50 RHAG	Homo sapiens (human)
Rhesus glycoproteins mediate ammonium transport	Ammonium transporter Rh type A Ammonium transporter Rh type B Ammonium transporter Rh type C	Q02094 Q9H310 Q9UBD6	C15orf6 CDRC2 PDRC2 RH50 RHAG RHBG RHCG RHGK	Homo sapiens (human)

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