ADORA2B mediated anti-inflammatory cytokines production

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
cAMPPKA tetramer:4xcAMPPKA tetramerPRKACA,PRKACB,PRKACGcAMP:PKA regulatory subunitPKA catalytic subunitsATPp-S133-CREB1CREBADPAde-RibADORA2B:Ade-RibADORA2BAde-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDPHeterotrimeric G-protein Gs (inactive)GTPGDPADORA2B:Ade-Rib:Heterotrimeric G-protein Gs:GTPGs:GTPG-protein beta-gamma complexAdenylate cyclase (Mg2+ cofactor)Gs-activated adenylate cyclaseATPPPiIL6 genep-S133-CREB1:IL6 geneIL6
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025