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MIRAGE
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
E2F1/2/3:DP1/2RB1 mutants (E2F binding)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O96020 G1/S-specific cyclin-E2
  • CCNE2
 view
P06400 Retinoblastoma-associated protein
  • RB1
 view
P46527 Cyclin-dependent kinase inhibitor 1B
  • CDKN1B
  • KIP1
  • p27
 view
Q01094 Transcription factor E2F1
  • E2F1
  • RBBP3
 view
Q14209 Transcription factor E2F2
  • E2F2
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025