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luminal breast carcinoma A
Summary
- Synonym
-
- Luminal A Breast Carcinoma
- Definition
- A breast carcinoma that is characterized by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3.
- Super Class
- breast carcinoma
External Links
- Disease Ontology
- DOID:0060548
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31 | ACACA | acetyl-CoA carboxylase alpha | |
| 142 | PARP1 | poly(ADP-ribose) polymerase 1 | |
| 1012 | CDH13 | cadherin 13 | |
| 1588 | CYP19A1 | cytochrome P450 family 19 subfamily A member 1 | |
| 2194 | FASN | fatty acid synthase | |
| 3161 | HMMR | hyaluronan mediated motility receptor | |
| 3418 | IDH2 | isocitrate dehydrogenase (NADP(+)) 2 | |
| 5162 | PDHB | pyruvate dehydrogenase E1 subunit beta | |
| 5290 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | |
| 5335 | PLCG1 | phospholipase C gamma 1 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | |
| Q13085 | Acetyl-CoA carboxylase 1 | |
| Q13478 | Interleukin-18 receptor 1 |
