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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
graft-versus-host disease
Summary
- Synonym
-
- GvHD
- graft versus host disease
- Definition
- An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.
- Super Class
- immune system disease
External Links
- Disease Ontology
- DOID:0081267
- Mondo Disease Ontology
- MeSH
- ORDO
- OMIM
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3558 | IL2 | interleukin 2 | |
| 3586 | IL10 | interleukin 10 | |
| 3588 | IL10RB | interleukin 10 receptor subunit beta | |
| 3718 | JAK3 | Janus kinase 3 | |
| 4288 | MKI67 | marker of proliferation Ki-67 | |
| 5155 | PDGFB | platelet derived growth factor subunit B | |
| 6402 | SELL | selectin L | |
| 7035 | TFPI | tissue factor pathway inhibitor | |
| 7157 | TP53 | tumor protein p53 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 15234 | Hgf | hepatocyte growth factor | |
| 15481 | Hspa8 | heat shock protein 8 | |
| 15978 | Ifng | interferon gamma | |
| 16153 | Il10 | interleukin 10 | |
| 16155 | Il10rb | interleukin 10 receptor, beta | |
| 16175 | Il1a | interleukin 1 alpha | |
| 16181 | Il1rn | interleukin 1 receptor antagonist | |
| 16183 | Il2 | interleukin 2 | |
| 17345 | Mki67 | antigen identified by monoclonal antibody Ki 67 | |
| 18591 | Pdgfb | platelet derived growth factor, B polypeptide |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 60582 | Il1rn | interleukin 1 receptor antagonist | |
| 65270 | Abo3 | histo-blood group ABO system transferase 3 | |
| 83785 | Vegfa | vascular endothelial growth factor A | |
| 116562 | Il2 | interleukin 2 | |
| 246097 | Fas | Fas cell surface death receptor | |
| 296504 | Abo2 | histo-blood group ABO system transferase 2 | |
| 304966 | Fcgr3a | Fc gamma receptor 3A | |
| 100301568 | Abo | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 563897 | gbgt1l5 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5 | |
| 566487 | gbgt1l2 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2 | |
| 100005565 | gbgt1l8 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8 | |
| 100005704 | gbgt1l9 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 495825 | abo.3.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog | Xenopus laevis (African clawed frog) | |
| 549437 | abo.3 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 | Xenopus tropicalis (tropical clawed frog) | |
| 549858 | abo.2 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 | Xenopus tropicalis (tropical clawed frog) | |
| 550054 | abo | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100497509 | abo.4 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 | Xenopus tropicalis (tropical clawed frog) | |
| 108698211 | abo.2.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 108698863 | abo.4.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog | Xenopus laevis (African clawed frog) |
