age related macular degeneration

Summary
Synonym
  • Age Related Maculopathies
  • Age Related Maculopathy
  • Senile macular degeneration
  • Senile macular retinal degeneration
  • age-related macular degeneration
Definition
A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.
Super Class
autosomal dominant disease degeneration of macula and posterior pole
External Links
Disease Ontology
DOID:10871
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 21 - 30 of 68 in total
Gene ID Gene Symbol Description Source
2878 GPX3 glutathione peroxidase 3
3290 HSD11B1 hydroxysteroid 11-beta dehydrogenase 1
3339 HSPG2 heparan sulfate proteoglycan 2
3383 ICAM1 intercellular adhesion molecule 1
3956 LGALS1 galectin 1
3990 LIPC lipase C, hepatic type
3992 FADS1 fatty acid desaturase 1
4023 LPL lipoprotein lipase
4125 MAN2B1 mannosidase alpha class 2B member 1
4153 MBL2 mannose binding lectin 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Displaying 1 entry
Gene ID Gene Symbol Description Source
83516 Ppargc1a PPARG coactivator 1 alpha

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024