Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sickle cell anemia
Summary
- Synonym
-
- Hb SC disease
- Hb-S/Hb-C disease
- Hb-SS disease without crisis
- Hemoglobin S disease without crisis
- Sickle-cell/Hb-C disease without crisis
- drepanocytosis
- haemoglobin SC disease
- hemoglobin SC disease
- sickle cell anaemia
- Definition
- A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
- Super Class
- autosomal recessive disease blood protein disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 338 | APOB | apolipoprotein B | |
| 629 | CFB | complement factor B | |
| 718 | C3 | complement C3 | |
| 948 | CD36 | CD36 molecule (CD36 blood group) | |
| 959 | CD40LG | CD40 ligand | |
| 1557 | CYP2C19 | cytochrome P450 family 2 subfamily C member 19 | |
| 2147 | F2 | coagulation factor II, thrombin | |
| 2152 | F3 | coagulation factor III, tissue factor | |
| 2876 | GPX1 | glutathione peroxidase 1 | |
| 3043 | HBB | hemoglobin subunit beta |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12266 | C3 | complement component 3 | |
| 12491 | Cd36 | CD36 molecule | |
| 13095 | Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | |
| 14061 | F2 | coagulation factor II | |
| 14066 | F3 | coagulation factor III | |
| 14775 | Gpx1 | glutathione peroxidase 1 | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | |
| 14962 | Cfb | complement factor B | |
| 15275 | Hk1 | hexokinase 1 | |
| 18127 | Nos3 | nitric oxide synthase 3, endothelial cell |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24600 | Nos3 | nitric oxide synthase 3 | |
| 24835 | Tnf | tumor necrosis factor | |
| 25058 | Hk1 | hexokinase 1 | |
| 29583 | Pecam1 | platelet and endothelial cell adhesion molecule 1 | |
| 54225 | Apob | apolipoprotein B | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 84024 | Pon1 | paraoxonase 1 | |
| 84349 | Cd40lg | CD40 ligand | |
| 94203 | Pgf | placental growth factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171999 | poml-2 | Arylesterase | |
| 176673 | scav-3 | Sensory neuron membrane protein 2 | |
| 176787 | scav-2 | SCAVenger receptor (CD36 family) related | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like |
