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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sickle cell anemia
Summary
- Synonym
-
- Hb SC disease
- Hb-S/Hb-C disease
- Hb-SS disease without crisis
- Hemoglobin S disease without crisis
- Sickle-cell/Hb-C disease without crisis
- drepanocytosis
- haemoglobin SC disease
- hemoglobin SC disease
- sickle cell anaemia
- Definition
- A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
- Super Class
- autosomal recessive disease blood protein disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1636 | ACE | angiotensin I converting enzyme | |
| 1727 | CYB5R3 | cytochrome b5 reductase 3 | |
| 2215 | FCGR3B | Fc gamma receptor IIIb | |
| 2224 | FDPS | farnesyl diphosphate synthase | |
| 2271 | FH | fumarate hydratase | |
| 2519 | FUCA2 | alpha-L-fucosidase 2 | |
| 2523 | FUT1 | fucosyltransferase 1 (H blood group) | |
| 2539 | G6PD | glucose-6-phosphate dehydrogenase | |
| 2571 | GAD1 | glutamate decarboxylase 1 | |
| 2597 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P21589 | 5'-nucleotidase | |
| P21964 | Catechol O-methyltransferase | |
| P22309 | UDP-glucuronosyltransferase 1A1 | |
| P22310 | UDP-glucuronosyltransferase 1A4 | |
| P28907 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | |
| P29218 | Inositol monophosphatase 1 | |
| P35247 | Pulmonary surfactant-associated protein D | |
| P35503 | UDP-glucuronosyltransferase 1A3 | |
| P35504 | UDP-glucuronosyltransferase 1A5 | |
| P37837 | Transaldolase |
