adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 1 - 10 of 38 in total
Gene ID Gene Symbol Description Source
12 SERPINA3 serpin family A member 3
177 AGER advanced glycosylation end-product specific receptor
259 AMBP alpha-1-microglobulin/bikunin precursor
718 C3 complement C3
719 C3AR1 complement C3a receptor 1
727 C5 complement C5
728 C5AR1 complement C5a receptor 1
1906 EDN1 endothelin 1
2152 F3 coagulation factor III, tissue factor
3308 HSPA4 heat shock protein family A (Hsp70) member 4
Displaying entries 11 - 20 of 36 in total
Gene ID Gene Symbol Description Source
16168 Il15 interleukin 15
16181 Il1rn interleukin 1 receptor antagonist
16198 Il9 interleukin 9
16625 Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C
16846 Lep leptin
16992 Lta lymphotoxin A
17195 Mbl2 mannose-binding lectin (protein C) 2
17395 Mmp9 matrix metallopeptidase 9
17829 Muc1 mucin 1, transmembrane
20388 Sftpb surfactant associated protein B
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
25350 Sftpd surfactant protein D
25377 Ambp alpha-1-microglobulin/bikunin precursor
25464 Icam1 intercellular adhesion molecule 1
25608 Lep leptin
25625 Tnfrsf1a TNF receptor superfamily member 1A
25670 Il15 interleukin 15
54320 Pdpn podoplanin
58966 Ramp2 receptor activity modifying protein 2
60582 Il1rn interleukin 1 receptor antagonist
81687 Mmp9 matrix metallopeptidase 9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024