Sjogren's syndrome

Summary
Synonym
  • Sicca syndrome
  • Sjogren syndrome
  • xerodermosteosis
Definition
An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Super Class
autoimmune disease of exocrine system
Disease Ontology
DOID:12894
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 21 - 30 of 46 in total
Gene ID Gene Symbol Description Source
3558 IL2 interleukin 2
3559 IL2RA interleukin 2 receptor subunit alpha
3565 IL4 interleukin 4
3569 IL6 interleukin 6
3586 IL10 interleukin 10
3596 IL13 interleukin 13
4049 LTA lymphotoxin alpha
4314 MMP3 matrix metallopeptidase 3
4318 MMP9 matrix metallopeptidase 9
4586 MUC5AC mucin 5AC, oligomeric mucus/gel-forming
Displaying entries 31 - 37 of 37 in total
Gene ID Gene Symbol Description Source
21947 Cd40lg CD40 ligand
22352 Vim vimentin
24099 Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b
59013 Hnrnph1 heterogeneous nuclear ribonucleoprotein H1
69550 Bst2 bone marrow stromal cell antigen 2
209590 Il23r interleukin 23 receptor
239611 Muc19 mucin 19
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
116562 Il2 interleukin 2
117029 Ccr5 C-C motif chemokine receptor 5
246097 Fas Fas cell surface death receptor
287287 Il4 interleukin 4
378947 Bst2 bone marrow stromal cell antigen 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9

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Acknowledgements

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Last updated: December 9, 2024