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acute chest syndrome
Summary
- Synonym
-
- acute chest syndrome in sickle cell disease
- Definition
- A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.
- Super Class
- lung disease
External Links
- Disease Ontology
- DOID:1584
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 8692 | HYAL2 | hyaluronidase 2 | |
| 8693 | GALNT4 | polypeptide N-acetylgalactosaminyltransferase 4 | |
| 9388 | LIPG | lipase G, endothelial type | |
| 23305 | ACSL6 | acyl-CoA synthetase long chain family member 6 | |
| 23583 | SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | |
| 23659 | PLA2G15 | phospholipase A2 group XV | |
| 51703 | ACSL5 | acyl-CoA synthetase long chain family member 5 | |
| 54898 | ELOVL2 | ELOVL fatty acid elongase 2 | |
| 55902 | ACSS2 | acyl-CoA synthetase short chain family member 2 | |
| 64116 | SLC39A8 | solute carrier family 39 member 8 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9Y5X9 | Endothelial lipase |
