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Standards Ontologies Notations
asthma

Summary
Synonym
  • bronchial hyperreactivity
  • chronic obstructive asthma
  • chronic obstructive asthma with acute exacerbation
  • chronic obstructive asthma with status asthmaticus
Definition
A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
Super Class
bronchial disease
Disease Ontology
DOID:2841
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 206 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
101 ADAM8 ADAM metallopeptidase domain 8
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
134 ADORA1 adenosine A1 receptor
135 ADORA2A adenosine A2a receptor
142 PARP1 poly(ADP-ribose) polymerase 1
154 ADRB2 adrenoceptor beta 2
177 AGER advanced glycosylation end-product specific receptor
185 AGTR1 angiotensin II receptor type 1
186 AGTR2 angiotensin II receptor type 2
Displaying entries 1 - 10 of 191 in total
Gene ID Gene Symbol Description Source
11421 Ace angiotensin I converting enzyme
11501 Adam8 a disintegrin and metallopeptidase domain 8
11539 Adora1 adenosine A1 receptor
11540 Adora2a adenosine A2a receptor
11555 Adrb2 adrenergic receptor, beta 2
11596 Ager advanced glycosylation end product-specific receptor
11607 Agtr1a angiotensin II receptor, type 1a
11609 Agtr2 angiotensin II receptor, type 2
11699 Ambp alpha 1 microglobulin/bikunin precursor
12062 Bdkrb2 bradykinin receptor, beta 2
Displaying entries 91 - 100 of 112 in total
Gene ID Gene Symbol Description Source
170926 Cysltr2 cysteinyl leukotriene receptor 2
192155 Sftpb surfactant protein B
246097 Fas Fas cell surface death receptor
260320 F7 coagulation factor VII
286934 Havcr1 hepatitis A virus cellular receptor 1
286963 Cyp2d5 cytochrome P450, family 2, subfamily d, polypeptide 5
287222 Timd2 T-cell immunoglobulin and mucin domain containing 2
287287 Il4 interleukin 4
287561 Ccl7 C-C motif chemokine ligand 7
289211 Fcgr2b Fc gamma receptor 2B
Displaying entries 21 - 30 of 33 in total
Gene ID Gene Symbol Description Source
41286 TkR86C Tachykinin-like receptor at 86C
41549 Octbeta2R Octopamine beta2 receptor
42245 ChT Choline transporter
42795 VAChT Vesicular acetylcholine transporter
42803 Hmgcr HMG Coenzyme A reductase
42890 Orct2 Organic cation transporter 2
42891 Orct Organic cation transporter
43222 Tl Toll
43551 TkR99D Tachykinin-like receptor at 99D
44885 mys myospheroid
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
394082 slc18a3b solute carrier family 18 member 3b
406411 rhoaa ras homolog gene family, member Aa
406659 rhoac ras homolog gene family, member Ac
436718 rhocb ras homolog family member Cb
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
Displaying entries 11 - 14 of 14 in total
Gene ID Gene Symbol Description Source Organism
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
172841 45566 Organic cation transporter 1
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175504 pat-3 Integrin beta pat-3
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178118 trpa-1 Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog
178215 pgp-1 Multidrug resistance protein pgp-1
178274 cho-1 High-affinity choline transporter 1
Displaying all 8 entries
Gene ID Gene Symbol Description Source
850462 GIT1 Git1p
851171 HMG2 hydroxymethylglutaryl-CoA reductase (NADPH) HMG2
851977 CTS2 putative chitinase
853671 STE6 ATP-binding cassette a-factor transporter STE6
853978 NFT1 putative multidrug transporter NFT1
854394 STE13 Ste13p
854900 HMG1 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1
856294 RHO1 Rho family GTPase RHO1
The Human Phenotype Ontology
Displaying all 3 entries
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
HP:0000006 Autosomal dominant inheritance
HP:0002099 Asthma
Displaying 1 entry
Gene ID Gene Symbol Description
240 ALOX5 arachidonate 5-lipoxygenase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024