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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
- Super Class
- interstitial lung disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1672 | DEFB1 | defensin beta 1 | |
| 1906 | EDN1 | endothelin 1 | |
| 1956 | EGFR | epidermal growth factor receptor | |
| 1958 | EGR1 | early growth response 1 | |
| 1991 | ELANE | elastase, neutrophil expressed | |
| 3026 | HABP2 | hyaluronan binding protein 2 | |
| 3082 | HGF | hepatocyte growth factor | |
| 3326 | HSP90AB1 | heat shock protein 90 alpha family class B member 1 | |
| 3329 | HSPD1 | heat shock protein family D (Hsp60) member 1 | |
| 3383 | ICAM1 | intercellular adhesion molecule 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 16449 | Jag1 | jagged 1 | |
| 17128 | Smad4 | SMAD family member 4 | |
| 17195 | Mbl2 | mannose-binding lectin (protein C) 2 | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 17833 | Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | |
| 18024 | Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | |
| 18049 | Ngf | nerve growth factor | |
| 18128 | Notch1 | notch 1 | |
| 18595 | Pdgfra | platelet derived growth factor receptor, alpha polypeptide | |
| 19225 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 89824 | Chi3l1 | chitinase 3 like 1 | |
| 114099 | Cysltr1 | cysteinyl leukotriene receptor 1 | |
| 114114 | Dnm1l | dynamin 1-like | |
| 116510 | Timp1 | TIMP metallopeptidase inhibitor 1 | |
| 116553 | Il13 | interleukin 13 | |
| 116630 | Csf2 | colony stimulating factor 2 | |
| 117029 | Ccr5 | C-C motif chemokine receptor 5 | |
| 117108 | B3gat1 | beta-1,3-glucuronyltransferase 1 | |
| 192155 | Sftpb | surfactant protein B | |
| 287287 | Il4 | interleukin 4 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34282 | GlcAT-S | Glucuronyltransferase S | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30718 | notch1a | notch receptor 1a | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | |
| 548607 | b3gat1a | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100332644 | b3gat1b | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100037907 | b3gat1 | beta-1,3-glucuronyltransferase 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174517 | sqv-8 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8 | |
| 175182 | ver-1 | Protein ver-1 | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 175781 | daf-4 | Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 | |
| 179962 | gar-3 | Muscarinic acetylcholine receptor gar-3 |
