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Standards Ontologies Notations
pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 69 in total
Gene ID Gene Symbol Description Source
4312 MMP1 matrix metallopeptidase 1
4318 MMP9 matrix metallopeptidase 9
4586 MUC5AC mucin 5AC, oligomeric mucus/gel-forming
4780 NFE2L2 NFE2 like bZIP transcription factor 2
4803 NGF nerve growth factor
4851 NOTCH1 notch receptor 1
5054 SERPINE1 serpin family E member 1
5156 PDGFRA platelet derived growth factor receptor alpha
5328 PLAU plasminogen activator, urokinase
5743 PTGS2 prostaglandin-endoperoxide synthase 2
Displaying entries 11 - 20 of 56 in total
Gene ID Gene Symbol Description Source
12773 Ccr4 C-C motif chemokine receptor 4
12774 Ccr5 C-C motif chemokine receptor 5
12776 Ccr8 C-C motif chemokine receptor 8
12842 Col1a1 collagen, type I, alpha 1
12843 Col1a2 collagen, type I, alpha 2
12981 Csf2 colony stimulating factor 2 (granulocyte-macrophage)
13649 Egfr epidermal growth factor receptor
13653 Egr1 early growth response 1
15234 Hgf hepatocyte growth factor
15510 Hspd1 heat shock protein 1 (chaperonin)
Displaying entries 41 - 42 of 42 in total
Gene ID Gene Symbol Description Source
301252 Hsp90ab1 heat shock protein 90 alpha family class B member 1
310738 Ngf nerve growth factor
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31926 Idgf4 Imaginal disc growth factor 4
34189 Acer Angiotensin-converting enzyme-related
34282 GlcAT-S Glucuronyltransferase S
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174517 sqv-8 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175781 daf-4 Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase
176286 glp-1 glp-1/Notch intracellular domain
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178672 srp-3 Serpin domain-containing protein
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179962 gar-3 Muscarinic acetylcholine receptor gar-3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024