systemic scleroderma

Summary
Synonym
  • Scleroderma
  • Scleroderma syndrome
  • progressive systemic sclerosis
  • systemic sclerosis
Definition
A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Super Class
scleroderma
Disease Ontology
DOID:418
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 21 - 30 of 66 in total
Gene ID Gene Symbol Description Source
2313 FLI1 Fli-1 proto-oncogene, ETS transcription factor
2324 FLT4 fms related receptor tyrosine kinase 4
2355 FOSL2 FOS like 2, AP-1 transcription factor subunit
2833 CXCR3 C-X-C motif chemokine receptor 3
2878 GPX3 glutathione peroxidase 3
3082 HGF hepatocyte growth factor
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3146 HMGB1 high mobility group box 1
3383 ICAM1 intercellular adhesion molecule 1
3458 IFNG interferon gamma
Displaying entries 11 - 20 of 57 in total
Gene ID Gene Symbol Description Source
12825 Col3a1 collagen, type III, alpha 1
12842 Col1a1 collagen, type I, alpha 1
12870 Cp ceruloplasmin
12977 Csf1 colony stimulating factor 1 (macrophage)
13982 Esr1 estrogen receptor 1 (alpha)
14061 F2 coagulation factor II
14118 Fbn1 fibrillin 1
14257 Flt4 FMS-like tyrosine kinase 4
14284 Fosl2 fos-like antigen 2
14960 H2-Aa histocompatibility 2, class II antigen A, alpha
Displaying entries 21 - 30 of 36 in total
Gene ID Gene Symbol Description Source
29591 Tgfbr1 transforming growth factor, beta receptor 1
81687 Mmp9 matrix metallopeptidase 9
83785 Vegfa vascular endothelial growth factor A
84032 Col3a1 collagen type III alpha 1 chain
84475 Cxcr3 C-X-C motif chemokine receptor 3
89808 Cx3cl1 C-X3-C motif chemokine ligand 1
89824 Chi3l1 chitinase 3 like 1
114110 Flt4 Fms related receptor tyrosine kinase 4
116479 F11r F11 receptor
116553 Il13 interleukin 13
Displaying all 10 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42490 Mvl Malvolio
Displaying all 5 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
175182 ver-1 Protein ver-1
176076 fbn-1 EGF-like domain-containing protein
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176829 daf-1 Cell surface receptor daf-1
177044 smf-3 NRAMP-like transporter smf-3
178672 srp-3 Serpin domain-containing protein
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
851977 CTS2 putative chitinase

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024