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Standards Ontologies Notations
human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 41 - 50 of 56 in total
Gene ID Gene Symbol Description Source
6347 CCL2 C-C motif chemokine ligand 2
6352 CCL5 C-C motif chemokine ligand 5
6356 CCL11 C-C motif chemokine ligand 11
6403 SELP selectin P
7098 TLR3 toll like receptor 3
7124 TNF tumor necrosis factor
9021 SOCS3 suppressor of cytokine signaling 3
9332 CD163 CD163 molecule
29126 CD274 CD274 molecule
30835 CD209 CD209 molecule
Displaying entries 61 - 62 of 62 in total
Gene ID Gene Symbol Description Source
268373 Ppia peptidylprolyl isomerase A
100504404 H2-Ea histocompatibility 2, class II antigen E alpha
Displaying entries 11 - 20 of 25 in total
Gene ID Gene Symbol Description Source
25651 Selp selectin P
25670 Il15 interleukin 15
25712 Ifng interferon gamma
29397 Ccl11 C-C motif chemokine ligand 11
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
50692 Plaur plasminogen activator, urokinase receptor
54258 Cxcr1 C-X-C motif chemokine receptor 1
83613 Nefl neurofilament light chain
84349 Cd40lg CD40 ligand
117029 Ccr5 C-C motif chemokine receptor 5
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024