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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
human immunodeficiency virus infectious disease
Summary
- Synonym
-
- HIV infection
- Definition
- A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
- Super Class
- viral infectious disease
External Links
- Disease Ontology
- DOID:526
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 50615 | IL21R | interleukin 21 receptor | |
| 54210 | TREM1 | triggering receptor expressed on myeloid cells 1 | |
| 55904 | KMT2E | lysine methyltransferase 2E (inactive) | |
| 59067 | IL21 | interleukin 21 | |
| 340061 | STING1 | stimulator of interferon response cGAMP interactor 1 | |
| 729230 | CCR2 | C-C motif chemokine receptor 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18671 | Abcb1a | ATP-binding cassette, sub-family B member 1A | |
| 18793 | Plaur | plasminogen activator, urokinase receptor | |
| 19225 | Ptgs2 | prostaglandin-endoperoxide synthase 2 | |
| 20292 | Ccl11 | C-C motif chemokine ligand 11 | |
| 20296 | Ccl2 | C-C motif chemokine ligand 2 | |
| 20344 | Selp | selectin, platelet | |
| 20700 | Serpina1a | serine (or cysteine) peptidase inhibitor, clade A, member 1A | |
| 20701 | Serpina1b | serine (or cysteine) preptidase inhibitor, clade A, member 1B | |
| 20702 | Serpina1c | serine (or cysteine) peptidase inhibitor, clade A, member 1C | |
| 20703 | Serpina1d | serine (or cysteine) peptidase inhibitor, clade A, member 1D |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24536 | Lepr | leptin receptor | |
| 24588 | Nefm | neurofilament medium chain | |
| 24648 | Serpina1 | serpin family A member 1 | |
| 24770 | Ccl2 | C-C motif chemokine ligand 2 | |
| 24835 | Tnf | tumor necrosis factor | |
| 25325 | Il10 | interleukin 10 | |
| 25419 | Crp | C-reactive protein | |
| 25518 | Ppia | peptidylprolyl isomerase A | |
| 25601 | Oprm1 | opioid receptor, mu 1 |
