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human immunodeficiency virus infectious disease
Summary
- Synonym
-
- HIV infection
- Definition
- A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
- Super Class
- viral infectious disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 50615 | IL21R | interleukin 21 receptor | |
| 54210 | TREM1 | triggering receptor expressed on myeloid cells 1 | |
| 55904 | KMT2E | lysine methyltransferase 2E (inactive) | |
| 59067 | IL21 | interleukin 21 | |
| 340061 | STING1 | stimulator of interferon response cGAMP interactor 1 | |
| 729230 | CCR2 | C-C motif chemokine receptor 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 20704 | Serpina1e | serine (or cysteine) peptidase inhibitor, clade A, member 1E | |
| 21926 | Tnf | tumor necrosis factor | |
| 21939 | Cd40 | CD40 antigen | |
| 21947 | Cd40lg | CD40 ligand | |
| 24015 | Abce1 | ATP-binding cassette, sub-family E member 1 | |
| 58217 | Trem1 | triggering receptor expressed on myeloid cells 1 | |
| 60504 | Il21r | interleukin 21 receptor | |
| 60505 | Il21 | interleukin 21 | |
| 60533 | Cd274 | CD274 antigen | |
| 69165 | Cd209b | CD209b antigen |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 246097 | Fas | Fas cell surface death receptor | |
| 304966 | Fcgr3a | Fc gamma receptor 3A | |
| 353253 | Kir3dl1 | killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 | |
| 365769 | Il21 | interleukin 21 | |
| 100360977 | Ppial4d | peptidylprolyl isomerase A (cyclophilin A)-like 4D |
