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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
schizophrenia
Summary
- Synonym
-
- schizophrenia-1
- Definition
- A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness.
- Super Class
- psychotic disorder
External Links
- Disease Ontology
- DOID:5419
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
-
- 5521202
- 5694657
- 5689835
- 5689331
- 5661067
- 5660929
- 5620953
- 5574284
- 5559028
- 5694660
- 5519120
- 5486680
- 5486142
- 5485349
- 5485273
- 5465282
- 5462366
- 5444462
- 6189180
- 7378550
- 6828730
- 6810192
- 6423106
- 6315641
- 6294898
- 6283412
- 6189202
- 5428448
- 5800496
- 5790635
- 5784537
- 5776380
- 5762957
- 5752786
- 5699086
- 3606460
- 3720943
- 3713111
- 3707975
- 3623286
- 3623253
- 3606731
- 3606703
- 3606580
- 3758089
- 3579532
- 3530740
- 3530450
- 3041140
- 2674288
- 2663269
- 2654500
- 4358724
- 5428306
- 5428133
- 5293444
- 5285873
- 5085985
- 5085920
- 4843272
- 4438921
- 2175046
- 4354165
- 4353812
- 3841583
- 3819267
- 3818698
- 3806713
- 3785829
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 4684 | NCAM1 | neural cell adhesion molecule 1 | |
| 4803 | NGF | nerve growth factor | |
| 4842 | NOS1 | nitric oxide synthase 1 | |
| 4855 | NOTCH4 | notch receptor 4 | |
| 4914 | NTRK1 | neurotrophic receptor tyrosine kinase 1 | |
| 4915 | NTRK2 | neurotrophic receptor tyrosine kinase 2 | |
| 4923 | NTSR1 | neurotensin receptor 1 | |
| 4976 | OPA1 | OPA1 mitochondrial dynamin like GTPase | |
| 4982 | TNFRSF11B | TNF receptor superfamily member 11b | |
| 4988 | OPRM1 | opioid receptor mu 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12289 | Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | |
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 12661 | Chl1 | cell adhesion molecule L1-like | |
| 12799 | Cnp | 2',3'-cyclic nucleotide 3' phosphodiesterase | |
| 12801 | Cnr1 | cannabinoid receptor 1 | |
| 12846 | Comt | catechol-O-methyltransferase | |
| 13032 | Ctsc | cathepsin C | |
| 13162 | Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | |
| 13433 | Dnmt1 | DNA methyltransferase 1 | |
| 13489 | Drd2 | dopamine receptor D2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24185 | Akt1 | AKT serine/threonine kinase 1 | |
| 24267 | Comt | catechol-O-methyltransferase | |
| 24310 | Ace | angiotensin I converting enzyme | |
| 24318 | Drd2 | dopamine receptor D2 | |
| 24408 | Grin1 | glutamate ionotropic receptor NMDA type subunit 1 | |
| 24409 | Grin2a | glutamate ionotropic receptor NMDA type subunit 2A | |
| 24410 | Grin2b | glutamate ionotropic receptor NMDA type subunit 2B | |
| 24412 | Grin2d | glutamate ionotropic receptor NMDA type subunit 2D | |
| 24415 | Grm2 | glutamate metabotropic receptor 2 | |
| 24418 | Grm5 | glutamate metabotropic receptor 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 31364 | Fas2 | Fasciclin 2 | |
| 31792 | Nrg | Neuroglian | |
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 32162 | fw | furrowed | |
| 32273 | sno | strawberry notch | |
| 32661 | if | inflated | |
| 33007 | Dop2R | Dopamine 2-like receptor | |
| 33913 | CG9550 | uncharacterized protein | |
| 33914 | CG31637 | uncharacterized protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 403310 | cacna1da | calcium channel, voltage-dependent, L type, alpha 1D subunit, a | |
| 445060 | b3gat2 | beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) | |
| 556800 | chst3b | carbohydrate (chondroitin 6) sulfotransferase 3b | |
| 559721 | chst3a | carbohydrate (chondroitin 6) sulfotransferase 3a | |
| 561372 | comta | catechol-O-methyltransferase a | |
| 565370 | comtb | catechol-O-methyltransferase b | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373759 | cnr1.S | cannabinoid receptor 1 (brain) S homeolog | Xenopus laevis (African clawed frog) | |
| 378584 | drd2.L | dopamine receptor D2 L homeolog | Xenopus laevis (African clawed frog) | |
| 397761 | ncam1.S | neural cell adhesion molecule 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 397762 | ncam1.L | neural cell adhesion molecule 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 399170 | akt1.S | AKT serine/threonine kinase 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 399190 | fzd3.L | frizzled class receptor 3 L homeolog | Xenopus laevis (African clawed frog) | |
| 594928 | b3gat2 | beta-1,3-glucuronyltransferase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 733177 | b3gat2.S | beta-1,3-glucuronyltransferase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 100127346 | grin2a.L | glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog | Xenopus laevis (African clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175182 | ver-1 | Protein ver-1 | |
| 175999 | glr-2 | Glutamate receptor 2 | |
| 176204 | glr-1 | Glutamate receptor 1 | |
| 176240 | pat-2 | Integrin alpha pat-2 | |
| 176282 | lin-12 | lin-12/Notch intracellular domain | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 176304 | dat-1 | Sodium-dependent dopamine transporter | |
| 177078 | lad-2 | Ig-like domain-containing protein;Neuroglian | |
| 177602 | sax-7 | Fibronectin type-III domain-containing protein;Neuroglian | |
| 178167 | nlr-1 | Neurexin like receptor 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 851977 | CTS2 | putative chitinase | |
| 852470 | SMY2 | Smy2p | |
| 853313 | PBS2 | mitogen-activated protein kinase kinase PBS2 | |
| 853770 | BUD2 | GTPase-activating protein BUD2 | |
| 855999 | SYH1 | Syh1p | |
| 856382 | STE20 | mitogen-activated protein kinase kinase kinase kinase STE20 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002353 | EEG abnormality |
| HP:0000738 | Hallucinations |
| HP:0100753 | Schizophrenia |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0007086 | Social and occupational deterioration |
| HP:0000746 | Delusion |
